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The map label for this gene is xylA

Identifier: 186477093

GI number: 186477093

Start: 2627793

End: 2629118

Strand: Reverse

Name: xylA

Synonym: Bphy_2342

Alternate gene names: 186477093

Gene position: 2629118-2627793 (Counterclockwise)

Preceding gene: 186477097

Following gene: 186477092

Centisome position: 75.57

GC content: 60.56

Gene sequence:

>1326_bases
ATGTCTTACTTCGAACACTTGCCCGCTGTGCGCTACGAAGGCCCGCAGACGGACAACCCGTTCGCTTATCGCCATTACGA
CAAGGACAAGCTGGTGCTCGGCAAGCGCATGGAAGACCATCTGCGCGTTGCCGTTTGCTACTGGCACACGTTCGTTTGGC
CTGGTGCGGACATGTTCGGTCCCGGCACGTTCGAGCGTCCGTGGCACCACGCCGGCGACGCACTCGAAATGGCGCACGCG
AAGGCCGACCATGCGTTCGAGCTGTTCTCGAAACTGGGCACGCCCTTCTATACGTTCCATGATCTCGACGTCGCGCCCGA
AGGCGACAGCATCAAGAGCTACGTGAACAACTTCAAGGCAATGACGGACGTGCTCGCGCGCAAGCAGGAGCAGACGGGCA
TCAAGCTGCTGTGGGGCACGGCGAACCTGTTCTCGCATCCGCGCTATGCGGCGGGCGCAGCGACCAATCCGAATCCCGAC
GTATTCGCGTTTGCCGCGACGCAGGTCCTCAACGCGCTCGAAGCGACACAACGTCTGGGCGGAGCGAACTACGTGCTGTG
GGGCGGACGCGAAGGCTACGAGACGTTGCTCAATACGGATCTCAAGCGCGAGCGCGAGCAGCTTGGCCGTTTCATGAGCA
TGGTCGTCGAGCACAAGCACAAGACGGGCTTCAAGGGTGCGCTGCTGATCGAGCCGAAGCCGCAGGAACCGACCAAGCAT
CAGTACGACTACGACGTCGCGACGGTGCATGGCTTTCTCACGCAGTTCGGTCTGCAGGACGAAATCCGCGTGAACATCGA
GGCGAATCATGCAACGCTCGCCGGTCATTCGTTTCACCACGAAATCGCCAATGCGTTTGCGCTCGGCATCTTCGGCAGCG
TCGATGCAAATCGCGGCGATGCGCAAAACGGCTGGGACACGGACCAGTTCCCAAATAGTGTCGAAGAACTGACGCTCGCG
TTCTACGAGATTCTGCGCAACGGCGGCTTCACGACGGGCGGCATGAACTTCGATGCGAAGGTCCGGCGCCAGAGCATCGA
TCCCGAAGACATCGTGCATGGTCATATCGGTGCGATCGACGTGCTGGCGGTTGCATTGGAACGCGCCGCGCATCTGATCG
AGCACGACCGTCTGGCTGCGTTCAAGCAGCAGCGCTATGCGGGTTGGGACAGCGACTTCGGACGCAAGATACTGGCAGGC
GGCTATTCGCTCGAGTCGCTGGCAAGCGACGCCGTGCAGCGAAACATCGCGCCTCGTCATGTGAGCGGACAGCAGGAGCG
TCTGGAGAACATCGTCAATCAGGCGATCTTCTCATCCGCGAAATAG

Upstream 100 bases:

>100_bases
CGGATTTCGCAATTGCCGCGCAATCGCGCAAGCGTCAGCATGGCGTCACATCACGCACGGTTCGATGCGGGCGCATCGGC
CGACACTACAGGAGACGCGC

Downstream 100 bases:

>100_bases
CGCATTCAGGCAGCACGAAAAATCGTTAGCAGCGCCGGTAGATTTCGCAATTGCTCGGCCGGCGCACACGGCACACGCTG
TCGTGCACCCCGAAATGAGG

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSYFEHLPAVRYEGPQTDNPFAYRHYDKDKLVLGKRMEDHLRVAVCYWHTFVWPGADMFGPGTFERPWHHAGDALEMAHA
KADHAFELFSKLGTPFYTFHDLDVAPEGDSIKSYVNNFKAMTDVLARKQEQTGIKLLWGTANLFSHPRYAAGAATNPNPD
VFAFAATQVLNALEATQRLGGANYVLWGGREGYETLLNTDLKREREQLGRFMSMVVEHKHKTGFKGALLIEPKPQEPTKH
QYDYDVATVHGFLTQFGLQDEIRVNIEANHATLAGHSFHHEIANAFALGIFGSVDANRGDAQNGWDTDQFPNSVEELTLA
FYEILRNGGFTTGGMNFDAKVRRQSIDPEDIVHGHIGAIDVLAVALERAAHLIEHDRLAAFKQQRYAGWDSDFGRKILAG
GYSLESLASDAVQRNIAPRHVSGQQERLENIVNQAIFSSAK

Sequences:

>Translated_441_residues
MSYFEHLPAVRYEGPQTDNPFAYRHYDKDKLVLGKRMEDHLRVAVCYWHTFVWPGADMFGPGTFERPWHHAGDALEMAHA
KADHAFELFSKLGTPFYTFHDLDVAPEGDSIKSYVNNFKAMTDVLARKQEQTGIKLLWGTANLFSHPRYAAGAATNPNPD
VFAFAATQVLNALEATQRLGGANYVLWGGREGYETLLNTDLKREREQLGRFMSMVVEHKHKTGFKGALLIEPKPQEPTKH
QYDYDVATVHGFLTQFGLQDEIRVNIEANHATLAGHSFHHEIANAFALGIFGSVDANRGDAQNGWDTDQFPNSVEELTLA
FYEILRNGGFTTGGMNFDAKVRRQSIDPEDIVHGHIGAIDVLAVALERAAHLIEHDRLAAFKQQRYAGWDSDFGRKILAG
GYSLESLASDAVQRNIAPRHVSGQQERLENIVNQAIFSSAK
>Mature_440_residues
SYFEHLPAVRYEGPQTDNPFAYRHYDKDKLVLGKRMEDHLRVAVCYWHTFVWPGADMFGPGTFERPWHHAGDALEMAHAK
ADHAFELFSKLGTPFYTFHDLDVAPEGDSIKSYVNNFKAMTDVLARKQEQTGIKLLWGTANLFSHPRYAAGAATNPNPDV
FAFAATQVLNALEATQRLGGANYVLWGGREGYETLLNTDLKREREQLGRFMSMVVEHKHKTGFKGALLIEPKPQEPTKHQ
YDYDVATVHGFLTQFGLQDEIRVNIEANHATLAGHSFHHEIANAFALGIFGSVDANRGDAQNGWDTDQFPNSVEELTLAF
YEILRNGGFTTGGMNFDAKVRRQSIDPEDIVHGHIGAIDVLAVALERAAHLIEHDRLAAFKQQRYAGWDSDFGRKILAGG
YSLESLASDAVQRNIAPRHVSGQQERLENIVNQAIFSSAK

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=436, Percent_Identity=68.8073394495413, Blast_Score=642, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_BURP8 (B2JFE9)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858563.1
- ProteinModelPortal:   B2JFE9
- SMR:   B2JFE9
- GeneID:   6243828
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2342
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- ProtClustDB:   PRK05474
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49398; Mature: 49267

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 100-100 ACT_SITE 103-103

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFEHLPAVRYEGPQTDNPFAYRHYDKDKLVLGKRMEDHLRVAVCYWHTFVWPGADMFG
CCHHHHCCCEECCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
PGTFERPWHHAGDALEMAHAKADHAFELFSKLGTPFYTFHDLDVAPEGDSIKSYVNNFKA
CCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHH
MTDVLARKQEQTGIKLLWGTANLFSHPRYAAGAATNPNPDVFAFAATQVLNALEATQRLG
HHHHHHHHHHCCCEEEEEECHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCC
GANYVLWGGREGYETLLNTDLKREREQLGRFMSMVVEHKHKTGFKGALLIEPKPQEPTKH
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
QYDYDVATVHGFLTQFGLQDEIRVNIEANHATLAGHSFHHEIANAFALGIFGSVDANRGD
CCCCHHHHHHHHHHHHCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCCC
AQNGWDTDQFPNSVEELTLAFYEILRNGGFTTGGMNFDAKVRRQSIDPEDIVHGHIGAID
CCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHCCCCHHHH
VLAVALERAAHLIEHDRLAAFKQQRYAGWDSDFGRKILAGGYSLESLASDAVQRNIAPRH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHCCCCHHHHHHHHHHHCCCCCC
VSGQQERLENIVNQAIFSSAK
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYFEHLPAVRYEGPQTDNPFAYRHYDKDKLVLGKRMEDHLRVAVCYWHTFVWPGADMFG
CHHHHCCCEECCCCCCCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
PGTFERPWHHAGDALEMAHAKADHAFELFSKLGTPFYTFHDLDVAPEGDSIKSYVNNFKA
CCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHH
MTDVLARKQEQTGIKLLWGTANLFSHPRYAAGAATNPNPDVFAFAATQVLNALEATQRLG
HHHHHHHHHHCCCEEEEEECHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCC
GANYVLWGGREGYETLLNTDLKREREQLGRFMSMVVEHKHKTGFKGALLIEPKPQEPTKH
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCC
QYDYDVATVHGFLTQFGLQDEIRVNIEANHATLAGHSFHHEIANAFALGIFGSVDANRGD
CCCCHHHHHHHHHHHHCCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCCCCCCC
AQNGWDTDQFPNSVEELTLAFYEILRNGGFTTGGMNFDAKVRRQSIDPEDIVHGHIGAID
CCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHCCCCHHHH
VLAVALERAAHLIEHDRLAAFKQQRYAGWDSDFGRKILAGGYSLESLASDAVQRNIAPRH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHCCCCHHHHHHHHHHHCCCCCC
VSGQQERLENIVNQAIFSSAK
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA