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The map label for this gene is pgm [H]

Identifier: 186477018

GI number: 186477018

Start: 2540508

End: 2541902

Strand: Reverse

Name: pgm [H]

Synonym: Bphy_2267

Alternate gene names: 186477018

Gene position: 2541902-2540508 (Counterclockwise)

Preceding gene: 186477033

Following gene: 186477017

Centisome position: 73.06

GC content: 62.58

Gene sequence:

>1395_bases
ATGATCTCGCAATCCATATTCAAGGCATATGACATCCGCGGAGTGATCGGCAAGACGCTCGACGCCGAGACCGCGCGTTC
GATCGGCCGCGCATTCGGCAGCGAAGTGCGCGCACAGGGCGGCGATGCCGTCGTCGTTGCGCGTGACGGACGTCTGTCCG
GTCCCGAACTGATCCAGGCGCTGTCTGACGGCCTGCGCTCGGCGGGTGTCGACGTGGTCAACGTCGGCATGGTGCCGACG
CCCGTCGGCTATTTCGCAGCCAGCGTGCCGCTCAAGCTGGACGGTGGCGAGCGCCGCATCGACTCGTGCATCGTGGTGAC
GGGCAGCCACAATCCGCCCGACTACAACGGCTTCAAGATGGTGCTGCGCGGCGCGGCCATCTACGGCGAGCAGATTCAAG
GCCTGTACAAACGCATCACCGAGAACCGCTTCGAGAGCGGCAACGGCACGTATCAGGAGTACGACATCGCCGACGCGTAC
CTCGAGCGCATCACGAGCGACATCAAGCTCGCGCGGCCGCTGAAGCTGGTGGTCGACACGGGCAACGGCGTCGCGGGCGG
CCTCGCGCCGCGCCTGTTCAAGGCGCTCGGCTGCGAACTGGTCGAACTGTTCACGGAGATCGACGGCAACTTCCCGAATC
ACCATCCGGACCCGGCGCATCCCGAGAACCTGCAGGACGTGATTCGCGCGCTGAAGGAAACGGACGCCGAGATCGGCTTT
GCGTTCGACGGCGACGGCGATCGTCTGGGCGTGGTCACGAAGGACGGCCAGATCATTTATCCCGACCGTCAGCTGATGCT
GTTCGCCGAAGAAGTGCTGTCGCGCAACAAGGGCGCGCAGATCATTTACGACGTGAAGTGCACGCGTAATCTCGCGAAGT
GGGTCAAGGAGAAGGGCGGCGAGCCGTTGATGTGGAAGACGGGGCACTCGCTGGTGAAGGCGAAGCTGCGCGAAACGGGC
GCGCCGCTGGCGGGCGAAATGAGCGGCCACGTGTTCTTCAAGGACCGCTGGTATGGGTTCGACGATGGCTTGTACACGGG
TGCGCGTCTGCTCGAAATCCTCGCACGCGTGCAGGACCCGAGCGCGCTGCTCAACAGCCTGCCGAATTCGCATTCGACGC
CGGAATTGCAGCTAAAGCTCCAGGAAGGCGAAAACTTTGAATTGATCGCGCGTTTGCAGAAGAGCGCAACGTTTCCCGAC
GCCGATCAGGTTGTGACGATTGACGGCTTGCGCGTCGAGTATCCTGATGGATTCGGGCTGGCGCGCTCGTCGAATACGAC
GCCTGTCGTTGTCATGAGGTTTGAGGCCGACAATGATGCGGCCTTGAAGAGGATTCAGGAAGACTTCCGCCGTGTCATTC
TGGCCGAGAAGGCTGACGCGAAGTTGCCGTTCTGA

Upstream 100 bases:

>100_bases
GCGCAATTATAAGTTGTATCCGGATCGCTTCCGGCAAGCCACAGTGCCATGACCACGCTGTGTCAAACCCATTTCCCATT
GCACGTAAGTGAGCCAATCC

Downstream 100 bases:

>100_bases
TTTCCTGGTTATTGTTTTCAAGCTGTGTGCGACGCCTTTCACCTCAAGGCGTCGTTTTTTTGCTCGCGGCCGCGTGACGG
TTTCTGCTGGCAGCGTTGCG

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MISQSIFKAYDIRGVIGKTLDAETARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELIQALSDGLRSAGVDVVNVGMVPT
PVGYFAASVPLKLDGGERRIDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQGLYKRITENRFESGNGTYQEYDIADAY
LERITSDIKLARPLKLVVDTGNGVAGGLAPRLFKALGCELVELFTEIDGNFPNHHPDPAHPENLQDVIRALKETDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNKGAQIIYDVKCTRNLAKWVKEKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARVQDPSALLNSLPNSHSTPELQLKLQEGENFELIARLQKSATFPD
ADQVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEADNDAALKRIQEDFRRVILAEKADAKLPF

Sequences:

>Translated_464_residues
MISQSIFKAYDIRGVIGKTLDAETARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELIQALSDGLRSAGVDVVNVGMVPT
PVGYFAASVPLKLDGGERRIDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQGLYKRITENRFESGNGTYQEYDIADAY
LERITSDIKLARPLKLVVDTGNGVAGGLAPRLFKALGCELVELFTEIDGNFPNHHPDPAHPENLQDVIRALKETDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNKGAQIIYDVKCTRNLAKWVKEKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARVQDPSALLNSLPNSHSTPELQLKLQEGENFELIARLQKSATFPD
ADQVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEADNDAALKRIQEDFRRVILAEKADAKLPF
>Mature_464_residues
MISQSIFKAYDIRGVIGKTLDAETARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELIQALSDGLRSAGVDVVNVGMVPT
PVGYFAASVPLKLDGGERRIDSCIVVTGSHNPPDYNGFKMVLRGAAIYGEQIQGLYKRITENRFESGNGTYQEYDIADAY
LERITSDIKLARPLKLVVDTGNGVAGGLAPRLFKALGCELVELFTEIDGNFPNHHPDPAHPENLQDVIRALKETDAEIGF
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNKGAQIIYDVKCTRNLAKWVKEKGGEPLMWKTGHSLVKAKLRETG
APLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARVQDPSALLNSLPNSHSTPELQLKLQEGENFELIARLQKSATFPD
ADQVVTIDGLRVEYPDGFGLARSSNTTPVVVMRFEADNDAALKRIQEDFRRVILAEKADAKLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=458, Percent_Identity=36.4628820960699, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789566, Length=485, Percent_Identity=24.7422680412371, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 50826; Mature: 50826

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISQSIFKAYDIRGVIGKTLDAETARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELIQA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LSDGLRSAGVDVVNVGMVPTPVGYFAASVPLKLDGGERRIDSCIVVTGSHNPPDYNGFKM
HHHHHHHCCCCEEEECCCCCCHHHHHEECCEEECCCCEEECEEEEEECCCCCCCCCHHHH
VLRGAAIYGEQIQGLYKRITENRFESGNGTYQEYDIADAYLERITSDIKLARPLKLVVDT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEEEC
GNGVAGGLAPRLFKALGCELVELFTEIDGNFPNHHPDPAHPENLQDVIRALKETDAEIGF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNKGAQIIYDVKCTRNLAKWVKEKGG
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCC
EPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARVQDP
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCH
SALLNSLPNSHSTPELQLKLQEGENFELIARLQKSATFPDADQVVTIDGLRVEYPDGFGL
HHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCEEEECCCCCCC
ARSSNTTPVVVMRFEADNDAALKRIQEDFRRVILAEKADAKLPF
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISQSIFKAYDIRGVIGKTLDAETARSIGRAFGSEVRAQGGDAVVVARDGRLSGPELIQA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
LSDGLRSAGVDVVNVGMVPTPVGYFAASVPLKLDGGERRIDSCIVVTGSHNPPDYNGFKM
HHHHHHHCCCCEEEECCCCCCHHHHHEECCEEECCCCEEECEEEEEECCCCCCCCCHHHH
VLRGAAIYGEQIQGLYKRITENRFESGNGTYQEYDIADAYLERITSDIKLARPLKLVVDT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEEEC
GNGVAGGLAPRLFKALGCELVELFTEIDGNFPNHHPDPAHPENLQDVIRALKETDAEIGF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
AFDGDGDRLGVVTKDGQIIYPDRQLMLFAEEVLSRNKGAQIIYDVKCTRNLAKWVKEKGG
EECCCCCEEEEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCC
EPLMWKTGHSLVKAKLRETGAPLAGEMSGHVFFKDRWYGFDDGLYTGARLLEILARVQDP
CCEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCH
SALLNSLPNSHSTPELQLKLQEGENFELIARLQKSATFPDADQVVTIDGLRVEYPDGFGL
HHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCEEEECCCCCCC
ARSSNTTPVVVMRFEADNDAALKRIQEDFRRVILAEKADAKLPF
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]