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The map label for this gene is holC [H]

Identifier: 186476975

GI number: 186476975

Start: 2496782

End: 2497198

Strand: Reverse

Name: holC [H]

Synonym: Bphy_2224

Alternate gene names: 186476975

Gene position: 2497198-2496782 (Counterclockwise)

Preceding gene: 186476976

Following gene: 186476974

Centisome position: 71.78

GC content: 63.55

Gene sequence:

>417_bases
ATGACCCGAATCGACTTTCATTCGAACGTCGGCGATTCGTTGCTGTATGCATGCCGTCTCGTGCGCAAGGCGTATCAGGC
CGGCCAGCCGCTCGTCGTGCTAGCCGAGCCGCCGCGTCTGCGCGCGTTTGACGAGCAGTTGTGGACCTTCTCCGCACTGG
ATTTCATCCCGCACTGCCTCGCGACGAGTCCGCTCGCGGCGCAAACGCCCATCGTGCTCGCGTCGTCGCTCGACGAGGCG
CCGCATCATCAGATACTGTTGAATCTGGGCGCGACCGTGCCGCCGCAGTTCGCGCGCTTCGAGCGCCTGCTGGAAATCGT
CGGCAACGCGCCCGACGAACTGGCTGCGGGACGCGACCGCTATCGCTTCTATCGCGATCGCGGCTATGCTTTGAACAATT
ACAAGCAGGGCGCCTGA

Upstream 100 bases:

>100_bases
GGCCGTCCCGTGCCGCTGCTCGCGCAGTTCCTGATCGACCGCGCCGCACAATGACGCGTCGCAGTTCGATCGTACGCCAG
GCAGTAAACCGGGATCGCCG

Downstream 100 bases:

>100_bases
CCGGTTCCTGTCCGCTCGGTGCGCGGTCTTGTCCCGCATTCTTGTCCGATAGGCGCAGATCCGGCGCGTCCGATCTTTAA
AGGGAGAGTTTTCGTGTCCC

Product: DNA polymerase III subunit chi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MTRIDFHSNVGDSLLYACRLVRKAYQAGQPLVVLAEPPRLRAFDEQLWTFSALDFIPHCLATSPLAAQTPIVLASSLDEA
PHHQILLNLGATVPPQFARFERLLEIVGNAPDELAAGRDRYRFYRDRGYALNNYKQGA

Sequences:

>Translated_138_residues
MTRIDFHSNVGDSLLYACRLVRKAYQAGQPLVVLAEPPRLRAFDEQLWTFSALDFIPHCLATSPLAAQTPIVLASSLDEA
PHHQILLNLGATVPPQFARFERLLEIVGNAPDELAAGRDRYRFYRDRGYALNNYKQGA
>Mature_137_residues
TRIDFHSNVGDSLLYACRLVRKAYQAGQPLVVLAEPPRLRAFDEQLWTFSALDFIPHCLATSPLAAQTPIVLASSLDEAP
HHQILLNLGATVPPQFARFERLLEIVGNAPDELAAGRDRYRFYRDRGYALNNYKQGA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 15481; Mature: 15350

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIDFHSNVGDSLLYACRLVRKAYQAGQPLVVLAEPPRLRAFDEQLWTFSALDFIPHCL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ATSPLAAQTPIVLASSLDEAPHHQILLNLGATVPPQFARFERLLEIVGNAPDELAAGRDR
HCCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHH
YRFYRDRGYALNNYKQGA
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TRIDFHSNVGDSLLYACRLVRKAYQAGQPLVVLAEPPRLRAFDEQLWTFSALDFIPHCL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ATSPLAAQTPIVLASSLDEAPHHQILLNLGATVPPQFARFERLLEIVGNAPDELAAGRDR
HCCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHH
YRFYRDRGYALNNYKQGA
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9864319; 10984043 [H]