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The map label for this gene is ppa [H]

Identifier: 186476924

GI number: 186476924

Start: 2435389

End: 2435916

Strand: Reverse

Name: ppa [H]

Synonym: Bphy_2173

Alternate gene names: 186476924

Gene position: 2435916-2435389 (Counterclockwise)

Preceding gene: 186476928

Following gene: 186476920

Centisome position: 70.01

GC content: 60.61

Gene sequence:

>528_bases
ATGAGCTTCAATCACGTTCCCGCTGGTAAAGACCTTCCGCAAGACTTTAACGTCATCATCGAAATTCCGGCGCAAAGCGA
CCCCGTGAAGTACGAGGCCGACAAGGATCTGGGTCTGCTCGTCGTCGATCGCTTCATCGGCACGGGTATGCGCTATCCCG
CGAACTACGGCTTTATTCCGCAGACGCTGTCGGGCGACGGCGATCCCGTCGACGTGCTCGTGATCACGCCGTTCCCGCTG
CTGGCCGGCTCGGTGGTGCGCGCACGCGCGCTGGGCATGCTGCAGATGACGGACGAATCGGGCGTCGACGCGAAGTTGAT
CGCCGTGCCGCACGACAAGATCTGCCCGATGACGGCGGACCTGAAGTCGGTCGACGACGTGCCGCAATACCTGAAGGATC
AGATCAAGCACTTCTTCGAGCAGTACAAGGCGCTCGAAAAGGGCAAGTGGGTGAAGGTGGAAGGCTGGGCGGGCGTCGAC
GCCGCGCACAAGGAAATCACCGACGGCGTAGCGAACTACAAGAAGTAA

Upstream 100 bases:

>100_bases
AGGCACGCAGTATCCGCGCAGTGTGCGGTCTGCGGCGCCACGTCCCGTATCCGGCGGCGCCGCGCGCCATGTTCCCATTT
CATCCTGATCAGAGAGCGCC

Downstream 100 bases:

>100_bases
CGGGTTCACTCACGCTTCGTGGCTGACAGGACGCTCCCTCGGGAGCGTCTTTGTTTTTGGGCAACCCGTTGCGCTCGAAT
GGAGCGCCGACCCCTATGCG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSFNHVPAGKDLPQDFNVIIEIPAQSDPVKYEADKDLGLLVVDRFIGTGMRYPANYGFIPQTLSGDGDPVDVLVITPFPL
LAGSVVRARALGMLQMTDESGVDAKLIAVPHDKICPMTADLKSVDDVPQYLKDQIKHFFEQYKALEKGKWVKVEGWAGVD
AAHKEITDGVANYKK

Sequences:

>Translated_175_residues
MSFNHVPAGKDLPQDFNVIIEIPAQSDPVKYEADKDLGLLVVDRFIGTGMRYPANYGFIPQTLSGDGDPVDVLVITPFPL
LAGSVVRARALGMLQMTDESGVDAKLIAVPHDKICPMTADLKSVDDVPQYLKDQIKHFFEQYKALEKGKWVKVEGWAGVD
AAHKEITDGVANYKK
>Mature_174_residues
SFNHVPAGKDLPQDFNVIIEIPAQSDPVKYEADKDLGLLVVDRFIGTGMRYPANYGFIPQTLSGDGDPVDVLVITPFPLL
AGSVVRARALGMLQMTDESGVDAKLIAVPHDKICPMTADLKSVDDVPQYLKDQIKHFFEQYKALEKGKWVKVEGWAGVDA
AHKEITDGVANYKK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=175, Percent_Identity=61.1428571428571, Blast_Score=219, Evalue=1e-58,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19243; Mature: 19112

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNHVPAGKDLPQDFNVIIEIPAQSDPVKYEADKDLGLLVVDRFIGTGMRYPANYGFIP
CCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCC
QTLSGDGDPVDVLVITPFPLLAGSVVRARALGMLQMTDESGVDAKLIAVPHDKICPMTAD
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCCCCCC
LKSVDDVPQYLKDQIKHFFEQYKALEKGKWVKVEGWAGVDAAHKEITDGVANYKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFNHVPAGKDLPQDFNVIIEIPAQSDPVKYEADKDLGLLVVDRFIGTGMRYPANYGFIP
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCC
QTLSGDGDPVDVLVITPFPLLAGSVVRARALGMLQMTDESGVDAKLIAVPHDKICPMTAD
CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCCCCCCCCCC
LKSVDDVPQYLKDQIKHFFEQYKALEKGKWVKVEGWAGVDAAHKEITDGVANYKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]