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The map label for this gene is rpiA

Identifier: 186476451

GI number: 186476451

Start: 1927395

End: 1928090

Strand: Reverse

Name: rpiA

Synonym: Bphy_1693

Alternate gene names: 186476451

Gene position: 1928090-1927395 (Counterclockwise)

Preceding gene: 186476452

Following gene: 186476450

Centisome position: 55.42

GC content: 65.66

Gene sequence:

>696_bases
ATGACTCAAGACGAACTCAAGCAACTGGTCGGCCAGGCGGCCGCCGACTACGTGATCGCCAACGTGCCCGAAGGCACGAT
CATCGGCGTTGGCACCGGCTCGACCGCGAACTGTTTCATCGACGCGCTCGCCGCGCACAAAGCGCGCTTTCGCGGCGCCG
TGTCCAGCTCGGTCGCGACGACGGCGCGCCTGCAATCGCACGGTATTCCGGTGTTCGACCTGAACGACATCGAATCGCTG
CCCGTCTACGTCGACGGCGCCGACGAAATCGATCATGGTGGCGCGATGATCAAGGGCGGTGGCGGCGCGCTCACGCGCGA
GAAAATCGTCGCGTCGGTGGCGGAGAAATTCCTCTGCATCGCCGACGCGAGCAAGGTCGTCGACGTGCTCGGCCAGTTTC
CGCTACCCGTCGAAGTCGTGCCGATGGCGCGCACGGCAATCGGCCGCCGTGTGACGGCCTTGGGCGGCGTGCCAATCGTG
CGTGTGACGAAGGACGGCGCGCCGTTCTTGACTGACAACGGCAATGAGATCATCGACGTCAAAGGCCTGCGCATCACCGA
TCCGCGCACGCTCGAAGCGCACGTCAACGCGTGGCCGGGTGTGGTGACGGTGGGCCTGTTCGCGGCGCGCGGCGCGGATC
TCTGCCTGCTCGGCACGCAGAAGGGTGTCGAGACGATCGTCTACCCGAATCGCTGA

Upstream 100 bases:

>100_bases
GTGCGCGCCAGATGCCGGGCCGGATGCGCAATAAACCCGGGCGAACGCCTCGACTCCGGTAAACTTGCAGTTTTTCCGCT
TGCCCAGGCATTTCCCCATC

Downstream 100 bases:

>100_bases
CAAACCAGCCGCCGGCGCGCGTGAGCGCAATGCGACCGCGCCGGCATCCCTCGCGCAGTGCCGTCGGCGACATTACTGAC
GAAGCAGCCTGGGCCAGCAC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MTQDELKQLVGQAAADYVIANVPEGTIIGVGTGSTANCFIDALAAHKARFRGAVSSSVATTARLQSHGIPVFDLNDIESL
PVYVDGADEIDHGGAMIKGGGGALTREKIVASVAEKFLCIADASKVVDVLGQFPLPVEVVPMARTAIGRRVTALGGVPIV
RVTKDGAPFLTDNGNEIIDVKGLRITDPRTLEAHVNAWPGVVTVGLFAARGADLCLLGTQKGVETIVYPNR

Sequences:

>Translated_231_residues
MTQDELKQLVGQAAADYVIANVPEGTIIGVGTGSTANCFIDALAAHKARFRGAVSSSVATTARLQSHGIPVFDLNDIESL
PVYVDGADEIDHGGAMIKGGGGALTREKIVASVAEKFLCIADASKVVDVLGQFPLPVEVVPMARTAIGRRVTALGGVPIV
RVTKDGAPFLTDNGNEIIDVKGLRITDPRTLEAHVNAWPGVVTVGLFAARGADLCLLGTQKGVETIVYPNR
>Mature_230_residues
TQDELKQLVGQAAADYVIANVPEGTIIGVGTGSTANCFIDALAAHKARFRGAVSSSVATTARLQSHGIPVFDLNDIESLP
VYVDGADEIDHGGAMIKGGGGALTREKIVASVAEKFLCIADASKVVDVLGQFPLPVEVVPMARTAIGRRVTALGGVPIVR
VTKDGAPFLTDNGNEIIDVKGLRITDPRTLEAHVNAWPGVVTVGLFAARGADLCLLGTQKGVETIVYPNR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=227, Percent_Identity=36.1233480176211, Blast_Score=107, Evalue=7e-24,
Organism=Escherichia coli, GI1789280, Length=227, Percent_Identity=62.9955947136564, Blast_Score=266, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17551758, Length=200, Percent_Identity=38, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=197, Percent_Identity=31.9796954314721, Blast_Score=85, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281364072, Length=209, Percent_Identity=35.8851674641148, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_BURP8 (B2JKP8)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001857921.1
- ProteinModelPortal:   B2JKP8
- SMR:   B2JKP8
- GeneID:   6243184
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_1693
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- ProtClustDB:   PRK00702
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24068; Mature: 23937

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKQLVGQAAADYVIANVPEGTIIGVGTGSTANCFIDALAAHKARFRGAVSSSVAT
CCHHHHHHHHHHHHHCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TARLQSHGIPVFDLNDIESLPVYVDGADEIDHGGAMIKGGGGALTREKIVASVAEKFLCI
HHHHHHCCCCEEECCCCCCCCEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
ADASKVVDVLGQFPLPVEVVPMARTAIGRRVTALGGVPIVRVTKDGAPFLTDNGNEIIDV
HHHHHHHHHHCCCCCCEEEECHHHHHHHCEEEECCCCEEEEEECCCCCEEECCCCEEEEE
KGLRITDPRTLEAHVNAWPGVVTVGLFAARGADLCLLGTQKGVETIVYPNR
CCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEECCC
>Mature Secondary Structure 
TQDELKQLVGQAAADYVIANVPEGTIIGVGTGSTANCFIDALAAHKARFRGAVSSSVAT
CHHHHHHHHHHHHHCEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TARLQSHGIPVFDLNDIESLPVYVDGADEIDHGGAMIKGGGGALTREKIVASVAEKFLCI
HHHHHHCCCCEEECCCCCCCCEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
ADASKVVDVLGQFPLPVEVVPMARTAIGRRVTALGGVPIVRVTKDGAPFLTDNGNEIIDV
HHHHHHHHHHCCCCCCEEEECHHHHHHHCEEEECCCCEEEEEECCCCCEEECCCCEEEEE
KGLRITDPRTLEAHVNAWPGVVTVGLFAARGADLCLLGTQKGVETIVYPNR
CCEEECCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA