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The map label for this gene is yusP [H]

Identifier: 186475931

GI number: 186475931

Start: 1306536

End: 1308038

Strand: Reverse

Name: yusP [H]

Synonym: Bphy_1166

Alternate gene names: 186475931

Gene position: 1308038-1306536 (Counterclockwise)

Preceding gene: 186475932

Following gene: 186475929

Centisome position: 37.6

GC content: 65.07

Gene sequence:

>1503_bases
ATGTCGAATCATCCCCAGACGAAGCGTCATCTCGTCATCGCGGCCGTCATGGCTTCGATGGCGATGGTGGCCATCGAGGC
CACCATCGTCTCGACGGCGATGCCGCAAATCGTTACGCAACTTGGCGGCCTGCGTCTTTACAGCTGGGTCTTCTCGTCGT
TCCTGCTCGCGCAGACGGCGATGACCGTCGTGTTCGGCAAGCTCGCCGATCTGTACGGCCGCAAGCCGACCGTGCTGGTC
GGCATCACTATCTTCCTGATCGGATCGATCGGCGCGGGCTTTGCGTGGTCGATGCCCGCGATGATCGCGTTCCGGCTGAT
ACAGGGCATGGGCGCAGGCGCGATCCAGCCGGTCACACTGACCATCGTCGCCGATCTGTATCCGGCGCGCGAGCGCGGCA
AGATCCAGGGCTATCTGGCGAGCGTCTGGGCGATCTCGGCCGTGATCGGTCCGATGGCGGGAGGGCTGCTGATCCGCGAT
CTGTCGTGGTCGTGGATCTTCTGGATCAACGTGCCCATCGGCATTCTGGCCGCGTCCGGCTTCATCACGTACCTGCACGA
AGAAAAGCGCCATCAGCGTCCGTCGATCGACATCATGGGCGCCGTGCTGTTCACGATCGCGATCGGCGCGCTGATGATGG
CGCTCACGGACGCCGGCTCGGAAACCGATGGCCGTGCGCTGTTCGAAGTCGCGTTGTGCGTCGTGGCGGGGGCGTGGTTC
GTGTGGCACGAGCGGCGCGTGTCCGAGCCGATGATTTCGTTCGCGCTGTGGAGCCAGCGGCCCATCGCCGCGTGCAATGC
GGCGACTGTGATGTCCGGCATGGCGCTGATGGGCCTCACCACCTTCCTGCCGATGTATGTGCAGGGCGTGCTGCATCAAT
CGCCTGTGATCGCGGGCCTCGCGCTGACGATGGTGATGCTCGGCTGGCCGTCGGGCGCAACGTTTACCGCGAAGTCGTTC
CACCGGCTCGGGCTGCGGCGCACGATGGTGGCGGGCAGCTTCTTCCTGCCGCTCGGCGCGATCGCGTTCGCGTTGCTGCA
GCCGGACGGGTCGCCCGTCACGGCGGGCGTGGGGTCGCTGGTGATGGGACTGGGCATGGGTATCGTCAGCGTCAGTTCGC
TGATCCTGATCCAGGAGATCGTGCAGCCGCTGCAACGCGGTTCGGCCACGGCGTCGAATCTGTTTTCACGGAATCTGGGC
AGTACGCTCGGTGCGGCGATCTTCGGCGCCGTGCTGAATTTCGGGCTGAGCCACTTCAAAGGCATGTCGATCACATCCGA
CCAATTGCGCTCGCTGCTCGACGCGACGCCGGGCGCGGCGCAGGCCGCGCTGTCGGGCAACGACATGGTGCGCGCGGCGC
TGCATCACTCGCTGCACCTGACGTTCCTGTCGATCTTCGTGATCTGTGTCGGTGCCGTGCTGTCGGTGATGATGGTGCCG
CACATCAAGATCGGCGGACAGCCGCGCGAGACGTCGGCAGCGGCGCATCTGTCCGAGATGTGA

Upstream 100 bases:

>100_bases
AGCGGTAGCATACAATTCTTTGCGCATCGAATGGCTTGCGAAACGCGCGCTGTTTCCGCGAACTTTCGGCACGTCCGCGC
AGCACACAACTACAGTCCCC

Downstream 100 bases:

>100_bases
GGATGCGTGACCCGGGTGAAGCGTGCATCACGACGCTTCGCCTGACGATTCGATCCCTTCCGCCATTCCCTCTGCTTCCG
TCGCGAGCCACTGACTGAAC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MSNHPQTKRHLVIAAVMASMAMVAIEATIVSTAMPQIVTQLGGLRLYSWVFSSFLLAQTAMTVVFGKLADLYGRKPTVLV
GITIFLIGSIGAGFAWSMPAMIAFRLIQGMGAGAIQPVTLTIVADLYPARERGKIQGYLASVWAISAVIGPMAGGLLIRD
LSWSWIFWINVPIGILAASGFITYLHEEKRHQRPSIDIMGAVLFTIAIGALMMALTDAGSETDGRALFEVALCVVAGAWF
VWHERRVSEPMISFALWSQRPIAACNAATVMSGMALMGLTTFLPMYVQGVLHQSPVIAGLALTMVMLGWPSGATFTAKSF
HRLGLRRTMVAGSFFLPLGAIAFALLQPDGSPVTAGVGSLVMGLGMGIVSVSSLILIQEIVQPLQRGSATASNLFSRNLG
STLGAAIFGAVLNFGLSHFKGMSITSDQLRSLLDATPGAAQAALSGNDMVRAALHHSLHLTFLSIFVICVGAVLSVMMVP
HIKIGGQPRETSAAAHLSEM

Sequences:

>Translated_500_residues
MSNHPQTKRHLVIAAVMASMAMVAIEATIVSTAMPQIVTQLGGLRLYSWVFSSFLLAQTAMTVVFGKLADLYGRKPTVLV
GITIFLIGSIGAGFAWSMPAMIAFRLIQGMGAGAIQPVTLTIVADLYPARERGKIQGYLASVWAISAVIGPMAGGLLIRD
LSWSWIFWINVPIGILAASGFITYLHEEKRHQRPSIDIMGAVLFTIAIGALMMALTDAGSETDGRALFEVALCVVAGAWF
VWHERRVSEPMISFALWSQRPIAACNAATVMSGMALMGLTTFLPMYVQGVLHQSPVIAGLALTMVMLGWPSGATFTAKSF
HRLGLRRTMVAGSFFLPLGAIAFALLQPDGSPVTAGVGSLVMGLGMGIVSVSSLILIQEIVQPLQRGSATASNLFSRNLG
STLGAAIFGAVLNFGLSHFKGMSITSDQLRSLLDATPGAAQAALSGNDMVRAALHHSLHLTFLSIFVICVGAVLSVMMVP
HIKIGGQPRETSAAAHLSEM
>Mature_499_residues
SNHPQTKRHLVIAAVMASMAMVAIEATIVSTAMPQIVTQLGGLRLYSWVFSSFLLAQTAMTVVFGKLADLYGRKPTVLVG
ITIFLIGSIGAGFAWSMPAMIAFRLIQGMGAGAIQPVTLTIVADLYPARERGKIQGYLASVWAISAVIGPMAGGLLIRDL
SWSWIFWINVPIGILAASGFITYLHEEKRHQRPSIDIMGAVLFTIAIGALMMALTDAGSETDGRALFEVALCVVAGAWFV
WHERRVSEPMISFALWSQRPIAACNAATVMSGMALMGLTTFLPMYVQGVLHQSPVIAGLALTMVMLGWPSGATFTAKSFH
RLGLRRTMVAGSFFLPLGAIAFALLQPDGSPVTAGVGSLVMGLGMGIVSVSSLILIQEIVQPLQRGSATASNLFSRNLGS
TLGAAIFGAVLNFGLSHFKGMSITSDQLRSLLDATPGAAQAALSGNDMVRAALHHSLHLTFLSIFVICVGAVLSVMMVPH
IKIGGQPRETSAAAHLSEM

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1790195, Length=357, Percent_Identity=27.4509803921569, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87081983, Length=309, Percent_Identity=27.831715210356, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789042, Length=342, Percent_Identity=28.9473684210526, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788710, Length=290, Percent_Identity=25.5172413793103, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788392, Length=353, Percent_Identity=27.7620396600567, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790146, Length=145, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI48994889, Length=116, Percent_Identity=31.8965517241379, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788509, Length=117, Percent_Identity=29.9145299145299, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=291, Percent_Identity=28.1786941580756, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319770, Length=444, Percent_Identity=23.8738738738739, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321663, Length=149, Percent_Identity=34.8993288590604, Blast_Score=98, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322958, Length=194, Percent_Identity=27.8350515463918, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325455, Length=129, Percent_Identity=29.4573643410853, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52954; Mature: 52822

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHPQTKRHLVIAAVMASMAMVAIEATIVSTAMPQIVTQLGGLRLYSWVFSSFLLAQTA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MTVVFGKLADLYGRKPTVLVGITIFLIGSIGAGFAWSMPAMIAFRLIQGMGAGAIQPVTL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
TIVADLYPARERGKIQGYLASVWAISAVIGPMAGGLLIRDLSWSWIFWINVPIGILAASG
EEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCHHHHHHHH
FITYLHEEKRHQRPSIDIMGAVLFTIAIGALMMALTDAGSETDGRALFEVALCVVAGAWF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VWHERRVSEPMISFALWSQRPIAACNAATVMSGMALMGLTTFLPMYVQGVLHQSPVIAGL
HHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALTMVMLGWPSGATFTAKSFHRLGLRRTMVAGSFFLPLGAIAFALLQPDGSPVTAGVGSL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VMGLGMGIVSVSSLILIQEIVQPLQRGSATASNLFSRNLGSTLGAAIFGAVLNFGLSHFK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMSITSDQLRSLLDATPGAAQAALSGNDMVRAALHHSLHLTFLSIFVICVGAVLSVMMVP
CCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HIKIGGQPRETSAAAHLSEM
CEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SNHPQTKRHLVIAAVMASMAMVAIEATIVSTAMPQIVTQLGGLRLYSWVFSSFLLAQTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MTVVFGKLADLYGRKPTVLVGITIFLIGSIGAGFAWSMPAMIAFRLIQGMGAGAIQPVTL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEE
TIVADLYPARERGKIQGYLASVWAISAVIGPMAGGLLIRDLSWSWIFWINVPIGILAASG
EEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCHHHHHHHH
FITYLHEEKRHQRPSIDIMGAVLFTIAIGALMMALTDAGSETDGRALFEVALCVVAGAWF
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VWHERRVSEPMISFALWSQRPIAACNAATVMSGMALMGLTTFLPMYVQGVLHQSPVIAGL
HHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALTMVMLGWPSGATFTAKSFHRLGLRRTMVAGSFFLPLGAIAFALLQPDGSPVTAGVGSL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VMGLGMGIVSVSSLILIQEIVQPLQRGSATASNLFSRNLGSTLGAAIFGAVLNFGLSHFK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMSITSDQLRSLLDATPGAAQAALSGNDMVRAALHHSLHLTFLSIFVICVGAVLSVMMVP
CCCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HIKIGGQPRETSAAAHLSEM
CEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]