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The map label for this gene is lhr [C]

Identifier: 186475932

GI number: 186475932

Start: 1308206

End: 1310440

Strand: Reverse

Name: lhr [C]

Synonym: Bphy_1167

Alternate gene names: 186475932

Gene position: 1310440-1308206 (Counterclockwise)

Preceding gene: 186475933

Following gene: 186475931

Centisome position: 37.67

GC content: 66.76

Gene sequence:

>2235_bases
ATGAGCTTGCCAGCTTCCGGCTCAACTGATTCGCGCAGCTTCGACCTGCTCGACGAGCGCATTCGCCGCTGGATCTGGCG
CGAAGGCTGGACCGAGCTGCGCGATGCGCAGGAGCGGGCCGTGCCCGCGCTGATCGACGCCGATCGCGATGTCATCATCG
CGGCAGCAACGGCCGCCGGCAAAACGGAAGCGGCGTTTCTCCCCATTCTGTCCAATCTGCTGCGCGACGCGCCATGCCGC
GGCTCGGTGCTGTACATCAGTCCGCTCAAGGCATTGATCAACGATCAATGGTCGCGCCTCGACGGCCTGTGCGAAGCGCT
GCAGATCCCCGTCACCGGCTGGCACGGAGATGTATCGTCGGGCCGCAAGCAGCGTTTCGTGAAGAACCCGACGGGCGTGC
TGCTGATTACGCCCGAATCGCTCGAAGCGATGTTCGTCACGCGCGGCGCGTCGCTGGCCGCGACCTTCGGCGCGCTGCGC
TATGTCGTCGTCGACGAGCTGCATGCGTTCATCGGCTCCGAGCGCGGCATGCAGTTGCAGTCGCTGATGCAGCGCGTCGA
CCGGGTGTGCGGGCGCCGTGTGCCGCGCGTTGGTCTGTCGGCGACGCTCGGCGACATGCGGCTCGCCGCCGGATTTCTGC
GCCCGAAAGGCGCAGCGAGCGTGCAGATCGTCGAGTCGGCTGAGGCCGGCCAGGAACTCAAGATTCTCGTCAAAGGCTAT
GTCGAGAAGCCGCCGCGCATCCAGTCCGAGCCGGGCATCGAAAACCCCGGCCTCGAAGATGTCGTGCCCGCCAGCACGGT
GGACGTCGCGAATCACATGTACAAGGTGCTGCGCGGCTCGAACAATCTGATCTTTCCGAATAGCCGACGCCAGGTCGAGT
TGTACGCCGACCTGTTGCGCCGCGCGTGCGAGCGAGACGGTTATCCGAACGAATTCTGGCCGCATCACGGCAGCCTGTCG
AAGGAGTTGCGCGAGCAGACCGAACAGGCGCTGAAGAAGGGCGACCGGCCTGCTAGCGCCATCTGCACGACGACGCTCGA
ACTCGGCATCGACATCGGCGCGGTGAAGAGCGTCGCGCAGGTGGGGGCGCCGCCGTCGGTGGCAAGCCTGCGGCAGCGGC
TCGGACGCTCGGGCCGGCGCAAGGGCGAAGCGGCGATTCTGCGCTGCTATTGTGTCGAAGCCGAGTTGCACAGCGGCTCA
GATCTGTCGGACCGGCTGCGCGAGAGCCTCGTGCAATCGGTGGCGATGGTGAACCTGCTGCTGCGCGGCTGGTTTGAACC
GCCGCGCGCGGGCGGCATGCATCCGTCCACACTGGTTCAGCAGATCCTGTCCATCATCGCCGAGCGGGGCGGCGCACGGG
CGAACGAACTGTGGGACACGCTCGTCGCCCAAGGCCCGTTCGGCGCGATCGACAAGGCGACGTTCACGGCGATCTTGCGC
GGTCTCGGCGCGAGGGATCTGCTCGTCCAGGAAGCGGGCGGCTTGCTGCTGCATGGCACGGCGGGAGAGCGCCTCGTCAA
CCACTACGCGTTCTACGCATCGTTTTCTACCGACGACGAGTTTCGCATCGTCGCGGGCGCGAGGGTGCTCGGCTCGGTGC
CCGTGTCGCGTCCTCTGGCGCCGGGGCAGGGCCTCGTGTTCGGCGGGCAGCGCTGGCGCGTGCAGGAAGTGGATGCCGCG
AAGAAGACCGTGTACGTGAAGCCCGATCAGGGCGGCGTGCCGCCTGTGTTCGACGGCAACGGTTCGCTCGTGCACGACGA
GGTGCGGCGCGAGATGTTCAATGTGCTGAAGGACGGCGCGCCCGTGGTGTTTCTCGATTCGACGGGTCGCGAACTGCTCG
AAGAGGCGCGCCGCTATTTCGCTTCGAACGAACTGGCGACGCGCGCCGTGTTCACGCATGGCGGCAACACGGTACTCGCC
ACCTGGTCGGGCGACTGGATCAACGATGCGCTAGTCGTGCTGCTGCGCGCCGAAGGGTTTGATGCGTGGAATCAGGGGCC
GACGGTGAGCGTGCGCGTTCAGGGCGCCGCTTCGGTGAAAGACGCGTTGCAACGTCTCGCGGCGCTGACGCCCGCGCAGA
CCGCGGACGCCTTGCGCGCGATCGGCAACATCGACAACGAAAAGTGGGACTCGACCTTGCCCGATGACGTGAAGCGCAGC
GCGTATGCGTCGCTGCGGCTCGATTTGCCGGGCGCGCAGGCGCTGGCGCGGCGGCTTGCTGCCGCGTGCGAGTGA

Upstream 100 bases:

>100_bases
CCGTCGGCGGATTGGCGCGAGCTGATCGGCAGCATGGATATCGAACGCGACACGGGCGGCGCGGCCGACATCGTCAACGA
CGCCGCTTCCGATAGCGACG

Downstream 100 bases:

>100_bases
GCGGGCTGCATGAAACCCGTCGGCACCTCGTCGCCGCATGTGCAACCGCGTGCGCGCACATCAATTAAGCGGTAGCATAC
AATTCTTTGCGCATCGAATG

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 744; Mature: 743

Protein sequence:

>744_residues
MSLPASGSTDSRSFDLLDERIRRWIWREGWTELRDAQERAVPALIDADRDVIIAAATAAGKTEAAFLPILSNLLRDAPCR
GSVLYISPLKALINDQWSRLDGLCEALQIPVTGWHGDVSSGRKQRFVKNPTGVLLITPESLEAMFVTRGASLAATFGALR
YVVVDELHAFIGSERGMQLQSLMQRVDRVCGRRVPRVGLSATLGDMRLAAGFLRPKGAASVQIVESAEAGQELKILVKGY
VEKPPRIQSEPGIENPGLEDVVPASTVDVANHMYKVLRGSNNLIFPNSRRQVELYADLLRRACERDGYPNEFWPHHGSLS
KELREQTEQALKKGDRPASAICTTTLELGIDIGAVKSVAQVGAPPSVASLRQRLGRSGRRKGEAAILRCYCVEAELHSGS
DLSDRLRESLVQSVAMVNLLLRGWFEPPRAGGMHPSTLVQQILSIIAERGGARANELWDTLVAQGPFGAIDKATFTAILR
GLGARDLLVQEAGGLLLHGTAGERLVNHYAFYASFSTDDEFRIVAGARVLGSVPVSRPLAPGQGLVFGGQRWRVQEVDAA
KKTVYVKPDQGGVPPVFDGNGSLVHDEVRREMFNVLKDGAPVVFLDSTGRELLEEARRYFASNELATRAVFTHGGNTVLA
TWSGDWINDALVVLLRAEGFDAWNQGPTVSVRVQGAASVKDALQRLAALTPAQTADALRAIGNIDNEKWDSTLPDDVKRS
AYASLRLDLPGAQALARRLAAACE

Sequences:

>Translated_744_residues
MSLPASGSTDSRSFDLLDERIRRWIWREGWTELRDAQERAVPALIDADRDVIIAAATAAGKTEAAFLPILSNLLRDAPCR
GSVLYISPLKALINDQWSRLDGLCEALQIPVTGWHGDVSSGRKQRFVKNPTGVLLITPESLEAMFVTRGASLAATFGALR
YVVVDELHAFIGSERGMQLQSLMQRVDRVCGRRVPRVGLSATLGDMRLAAGFLRPKGAASVQIVESAEAGQELKILVKGY
VEKPPRIQSEPGIENPGLEDVVPASTVDVANHMYKVLRGSNNLIFPNSRRQVELYADLLRRACERDGYPNEFWPHHGSLS
KELREQTEQALKKGDRPASAICTTTLELGIDIGAVKSVAQVGAPPSVASLRQRLGRSGRRKGEAAILRCYCVEAELHSGS
DLSDRLRESLVQSVAMVNLLLRGWFEPPRAGGMHPSTLVQQILSIIAERGGARANELWDTLVAQGPFGAIDKATFTAILR
GLGARDLLVQEAGGLLLHGTAGERLVNHYAFYASFSTDDEFRIVAGARVLGSVPVSRPLAPGQGLVFGGQRWRVQEVDAA
KKTVYVKPDQGGVPPVFDGNGSLVHDEVRREMFNVLKDGAPVVFLDSTGRELLEEARRYFASNELATRAVFTHGGNTVLA
TWSGDWINDALVVLLRAEGFDAWNQGPTVSVRVQGAASVKDALQRLAALTPAQTADALRAIGNIDNEKWDSTLPDDVKRS
AYASLRLDLPGAQALARRLAAACE
>Mature_743_residues
SLPASGSTDSRSFDLLDERIRRWIWREGWTELRDAQERAVPALIDADRDVIIAAATAAGKTEAAFLPILSNLLRDAPCRG
SVLYISPLKALINDQWSRLDGLCEALQIPVTGWHGDVSSGRKQRFVKNPTGVLLITPESLEAMFVTRGASLAATFGALRY
VVVDELHAFIGSERGMQLQSLMQRVDRVCGRRVPRVGLSATLGDMRLAAGFLRPKGAASVQIVESAEAGQELKILVKGYV
EKPPRIQSEPGIENPGLEDVVPASTVDVANHMYKVLRGSNNLIFPNSRRQVELYADLLRRACERDGYPNEFWPHHGSLSK
ELREQTEQALKKGDRPASAICTTTLELGIDIGAVKSVAQVGAPPSVASLRQRLGRSGRRKGEAAILRCYCVEAELHSGSD
LSDRLRESLVQSVAMVNLLLRGWFEPPRAGGMHPSTLVQQILSIIAERGGARANELWDTLVAQGPFGAIDKATFTAILRG
LGARDLLVQEAGGLLLHGTAGERLVNHYAFYASFSTDDEFRIVAGARVLGSVPVSRPLAPGQGLVFGGQRWRVQEVDAAK
KTVYVKPDQGGVPPVFDGNGSLVHDEVRREMFNVLKDGAPVVFLDSTGRELLEEARRYFASNELATRAVFTHGGNTVLAT
WSGDWINDALVVLLRAEGFDAWNQGPTVSVRVQGAASVKDALQRLAALTPAQTADALRAIGNIDNEKWDSTLPDDVKRSA
YASLRLDLPGAQALARRLAAACE

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI169218225, Length=422, Percent_Identity=22.5118483412322, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1787942, Length=656, Percent_Identity=26.3719512195122, Blast_Score=143, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17537127, Length=314, Percent_Identity=26.7515923566879, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI9755332, Length=385, Percent_Identity=22.3376623376623, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321020, Length=198, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28574898, Length=419, Percent_Identity=24.8210023866348, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 80799; Mature: 80668

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPASGSTDSRSFDLLDERIRRWIWREGWTELRDAQERAVPALIDADRDVIIAAATAAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHCCCCCCEEEEEECCCC
KTEAAFLPILSNLLRDAPCRGSVLYISPLKALINDQWSRLDGLCEALQIPVTGWHGDVSS
CCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRKQRFVKNPTGVLLITPESLEAMFVTRGASLAATFGALRYVVVDELHAFIGSERGMQLQ
CHHHHHHCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
SLMQRVDRVCGRRVPRVGLSATLGDMRLAAGFLRPKGAASVQIVESAEAGQELKILVKGY
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
VEKPPRIQSEPGIENPGLEDVVPASTVDVANHMYKVLRGSNNLIFPNSRRQVELYADLLR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHH
RACERDGYPNEFWPHHGSLSKELREQTEQALKKGDRPASAICTTTLELGIDIGAVKSVAQ
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
VGAPPSVASLRQRLGRSGRRKGEAAILRCYCVEAELHSGSDLSDRLRESLVQSVAMVNLL
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHH
LRGWFEPPRAGGMHPSTLVQQILSIIAERGGARANELWDTLVAQGPFGAIDKATFTAILR
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
GLGARDLLVQEAGGLLLHGTAGERLVNHYAFYASFSTDDEFRIVAGARVLGSVPVSRPLA
HCCHHHHHHHHCCCEEEECCCHHHHHHHHHEEEEECCCCCEEEEECHHHHCCCCCCCCCC
PGQGLVFGGQRWRVQEVDAAKKTVYVKPDQGGVPPVFDGNGSLVHDEVRREMFNVLKDGA
CCCCEEECCCCCEEHHHCCCCCEEEECCCCCCCCCEECCCCCEEHHHHHHHHHHHHHCCC
PVVFLDSTGRELLEEARRYFASNELATRAVFTHGGNTVLATWSGDWINDALVVLLRAEGF
CEEEECCCCHHHHHHHHHHHHCCCHHHHEEEECCCCEEEEECCCCHHHHHHHEEEECCCC
DAWNQGPTVSVRVQGAASVKDALQRLAALTPAQTADALRAIGNIDNEKWDSTLPDDVKRS
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
AYASLRLDLPGAQALARRLAAACE
HHHEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SLPASGSTDSRSFDLLDERIRRWIWREGWTELRDAQERAVPALIDADRDVIIAAATAAG
CCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHCCCCCCEEEEEECCCC
KTEAAFLPILSNLLRDAPCRGSVLYISPLKALINDQWSRLDGLCEALQIPVTGWHGDVSS
CCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRKQRFVKNPTGVLLITPESLEAMFVTRGASLAATFGALRYVVVDELHAFIGSERGMQLQ
CHHHHHHCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
SLMQRVDRVCGRRVPRVGLSATLGDMRLAAGFLRPKGAASVQIVESAEAGQELKILVKGY
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
VEKPPRIQSEPGIENPGLEDVVPASTVDVANHMYKVLRGSNNLIFPNSRRQVELYADLLR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHH
RACERDGYPNEFWPHHGSLSKELREQTEQALKKGDRPASAICTTTLELGIDIGAVKSVAQ
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
VGAPPSVASLRQRLGRSGRRKGEAAILRCYCVEAELHSGSDLSDRLRESLVQSVAMVNLL
CCCCCCHHHHHHHHCCCCCCCCCCEEEEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHH
LRGWFEPPRAGGMHPSTLVQQILSIIAERGGARANELWDTLVAQGPFGAIDKATFTAILR
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
GLGARDLLVQEAGGLLLHGTAGERLVNHYAFYASFSTDDEFRIVAGARVLGSVPVSRPLA
HCCHHHHHHHHCCCEEEECCCHHHHHHHHHEEEEECCCCCEEEEECHHHHCCCCCCCCCC
PGQGLVFGGQRWRVQEVDAAKKTVYVKPDQGGVPPVFDGNGSLVHDEVRREMFNVLKDGA
CCCCEEECCCCCEEHHHCCCCCEEEECCCCCCCCCEECCCCCEEHHHHHHHHHHHHHCCC
PVVFLDSTGRELLEEARRYFASNELATRAVFTHGGNTVLATWSGDWINDALVVLLRAEGF
CEEEECCCCHHHHHHHHHHHHCCCHHHHEEEECCCCEEEEECCCCHHHHHHHEEEECCCC
DAWNQGPTVSVRVQGAASVKDALQRLAALTPAQTADALRAIGNIDNEKWDSTLPDDVKRS
CCCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
AYASLRLDLPGAQALARRLAAACE
HHHEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]