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The map label for this gene is epsA [H]

Identifier: 186475825

GI number: 186475825

Start: 1190212

End: 1191393

Strand: Direct

Name: epsA [H]

Synonym: Bphy_1060

Alternate gene names: 186475825

Gene position: 1190212-1191393 (Clockwise)

Preceding gene: 186475824

Following gene: 186475826

Centisome position: 34.21

GC content: 64.89

Gene sequence:

>1182_bases
ATGCTGAAACGACACATCACGATATCTCTTGCGCTGACGACTTTTCTGTCGGCATGCGCGACCGCGCCGGGGAACTACCT
CGACACGTCGCGCCTGAAGGAAGACCAGCAGAACAAGCCTGCTGAGACGTACCCGGTCACGCTGATCGATGCCTCCGTCA
TCCAGAAGCAGCAGGCACAAACGGCGGACGCGATCGCGCATCAGGTGCTGCCGCCGCCGGGTCCGTTTGCCGATCCGACC
CAGTACGTCTATCGCATCGCGCCACAGGACATTCTCGGCATCACCGTGTGGGACCACCCGGAACTGACGACGCCGAACGG
CAGCACGCTGTCCTCGGGCGGCAACACCACGCAGACGCTCGGCGGCGCGTTGCAGCAGCCGTACACGCAGGCACTGCCTG
GCCAGGCCGATCCGTATGGGCAGACGGTCGCGCCCGACGGCACGATCTATTTCCCATTCGTCGGCCGAATCCGCGCGTCG
GGGCGGACGACGGCGCAAATCCGCGACGAGCTGTCGAAGAAGCTCGTGCCGTACATCCGTGACCCGCAAGTCGACGTGCG
CGTGCTGTCTTACCGCAGTCAGAAGGTGCAGGTGACGGGCGACGTGAAGACGCCGGGCCCGCTCGCGCTGTCCGATGTGC
CGCTCACGCTGGTCGACGCGATCACCCGCTCGGGCGGCTCGACGGACAACGCGGATCTGCAGCGCGTGCGTCTCACGCGC
AAGGGCAAGCTCTATGTGCTCGACGCGAACCGCATGCTCGACAAGGGCGACGCGACGCAGAACGTGATGCTCGAACCGGG
CGACATCGTCAACGTGCCGGACCGCAGCGACACGCGCATCTTCGTGATGGGCGAAGTGAAAACGCCGATCCCCGTGCCGA
TGAACAAGGGCGAGCTGACCATCGCCGATGCGCTCACGCAGGCGGGCGGCATTCTCGACACCGACGCCAACCCGCGCCAG
ATCTACGTGATGCGCGGCATGAAGGACAAGCCGACCACGCCAGACGTGTATCGCCTCGACATGACGCAGCCCGACGCGAT
CATGCTGTCGTCGCAATTCGAACTGCAGCCGATGGACGTGGTGTACGTCGGCACGGCCGCCTCGACGACGTTCAACCGCG
TGTTGCAGCAGGTGCTGCCGACGGTGCAGACGCTGTTCTATCTGAAGCAGTTGACGCGCTGA

Upstream 100 bases:

>100_bases
GCAGCGCCGACGTCGTCGATCCGCACGGACGCGACGAAGCCGTGTATCGCGACAGCCTCGCGCACATCGAACACCTCGTC
ATGGGATGGCTGAACAAAAT

Downstream 100 bases:

>100_bases
TGCCTTCATCGACGTCTGCATCGGCATTCCGTTGCGGACGCGTTGCCTGAACCGCTGCCCGCATGCCGGCGCTTCGCATC
CCGAACAGGACGGATGCAAC

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MLKRHITISLALTTFLSACATAPGNYLDTSRLKEDQQNKPAETYPVTLIDASVIQKQQAQTADAIAHQVLPPPGPFADPT
QYVYRIAPQDILGITVWDHPELTTPNGSTLSSGGNTTQTLGGALQQPYTQALPGQADPYGQTVAPDGTIYFPFVGRIRAS
GRTTAQIRDELSKKLVPYIRDPQVDVRVLSYRSQKVQVTGDVKTPGPLALSDVPLTLVDAITRSGGSTDNADLQRVRLTR
KGKLYVLDANRMLDKGDATQNVMLEPGDIVNVPDRSDTRIFVMGEVKTPIPVPMNKGELTIADALTQAGGILDTDANPRQ
IYVMRGMKDKPTTPDVYRLDMTQPDAIMLSSQFELQPMDVVYVGTAASTTFNRVLQQVLPTVQTLFYLKQLTR

Sequences:

>Translated_393_residues
MLKRHITISLALTTFLSACATAPGNYLDTSRLKEDQQNKPAETYPVTLIDASVIQKQQAQTADAIAHQVLPPPGPFADPT
QYVYRIAPQDILGITVWDHPELTTPNGSTLSSGGNTTQTLGGALQQPYTQALPGQADPYGQTVAPDGTIYFPFVGRIRAS
GRTTAQIRDELSKKLVPYIRDPQVDVRVLSYRSQKVQVTGDVKTPGPLALSDVPLTLVDAITRSGGSTDNADLQRVRLTR
KGKLYVLDANRMLDKGDATQNVMLEPGDIVNVPDRSDTRIFVMGEVKTPIPVPMNKGELTIADALTQAGGILDTDANPRQ
IYVMRGMKDKPTTPDVYRLDMTQPDAIMLSSQFELQPMDVVYVGTAASTTFNRVLQQVLPTVQTLFYLKQLTR
>Mature_393_residues
MLKRHITISLALTTFLSACATAPGNYLDTSRLKEDQQNKPAETYPVTLIDASVIQKQQAQTADAIAHQVLPPPGPFADPT
QYVYRIAPQDILGITVWDHPELTTPNGSTLSSGGNTTQTLGGALQQPYTQALPGQADPYGQTVAPDGTIYFPFVGRIRAS
GRTTAQIRDELSKKLVPYIRDPQVDVRVLSYRSQKVQVTGDVKTPGPLALSDVPLTLVDAITRSGGSTDNADLQRVRLTR
KGKLYVLDANRMLDKGDATQNVMLEPGDIVNVPDRSDTRIFVMGEVKTPIPVPMNKGELTIADALTQAGGILDTDANPRQ
IYVMRGMKDKPTTPDVYRLDMTQPDAIMLSSQFELQPMDVVYVGTAASTTFNRVLQQVLPTVQTLFYLKQLTR

Specific function: Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1788376, Length=392, Percent_Identity=35.4591836734694, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1787218, Length=407, Percent_Identity=33.9066339066339, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 42953; Mature: 42953

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRHITISLALTTFLSACATAPGNYLDTSRLKEDQQNKPAETYPVTLIDASVIQKQQAQ
CCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHH
TADAIAHQVLPPPGPFADPTQYVYRIAPQDILGITVWDHPELTTPNGSTLSSGGNTTQTL
HHHHHHHHCCCCCCCCCCHHHHHEEECCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHH
GGALQQPYTQALPGQADPYGQTVAPDGTIYFPFVGRIRASGRTTAQIRDELSKKLVPYIR
HHHHHCCHHHHCCCCCCCCCCEECCCCEEEECEEEEEECCCCCHHHHHHHHHHHHCCCCC
DPQVDVRVLSYRSQKVQVTGDVKTPGPLALSDVPLTLVDAITRSGGSTDNADLQRVRLTR
CCCCEEEEEEECCCEEEEEECCCCCCCEEECCCCHHHHHHHHHCCCCCCCCHHHHEEEEC
KGKLYVLDANRMLDKGDATQNVMLEPGDIVNVPDRSDTRIFVMGEVKTPIPVPMNKGELT
CCEEEEEECCHHCCCCCCCCCEEECCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCEE
IADALTQAGGILDTDANPRQIYVMRGMKDKPTTPDVYRLDMTQPDAIMLSSQFELQPMDV
HHHHHHHCCCEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCE
VYVGTAASTTFNRVLQQVLPTVQTLFYLKQLTR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKRHITISLALTTFLSACATAPGNYLDTSRLKEDQQNKPAETYPVTLIDASVIQKQQAQ
CCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHH
TADAIAHQVLPPPGPFADPTQYVYRIAPQDILGITVWDHPELTTPNGSTLSSGGNTTQTL
HHHHHHHHCCCCCCCCCCHHHHHEEECCCCEEEEEEECCCCCCCCCCCEECCCCCCHHHH
GGALQQPYTQALPGQADPYGQTVAPDGTIYFPFVGRIRASGRTTAQIRDELSKKLVPYIR
HHHHHCCHHHHCCCCCCCCCCEECCCCEEEECEEEEEECCCCCHHHHHHHHHHHHCCCCC
DPQVDVRVLSYRSQKVQVTGDVKTPGPLALSDVPLTLVDAITRSGGSTDNADLQRVRLTR
CCCCEEEEEEECCCEEEEEECCCCCCCEEECCCCHHHHHHHHHCCCCCCCCHHHHEEEEC
KGKLYVLDANRMLDKGDATQNVMLEPGDIVNVPDRSDTRIFVMGEVKTPIPVPMNKGELT
CCEEEEEECCHHCCCCCCCCCEEECCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCEE
IADALTQAGGILDTDANPRQIYVMRGMKDKPTTPDVYRLDMTQPDAIMLSSQFELQPMDV
HHHHHHHCCCEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCE
VYVGTAASTTFNRVLQQVLPTVQTLFYLKQLTR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]