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The map label for this gene is ptp [H]

Identifier: 186475824

GI number: 186475824

Start: 1189757

End: 1190218

Strand: Direct

Name: ptp [H]

Synonym: Bphy_1059

Alternate gene names: 186475824

Gene position: 1189757-1190218 (Clockwise)

Preceding gene: 186475823

Following gene: 186475825

Centisome position: 34.2

GC content: 66.02

Gene sequence:

>462_bases
ATGTTCGCGAACGTGCTGATCGTCTGCCATGCCAACGTGTGCCGCTCGCCCGCCGCCGAGTGGCTGTTCCGTTCCCGGCA
ACACGGACGCGGCGCGCGGCCCATCGCGTTTCGCTCGGCGGGTCTGCGCGCGATCGACGGACATGGCATGGACCCCGTGA
TGCGGCGTCTTCTCGAAGAACGCGGCGTCGATGGCGGCACGACGGGCGGGCATCGCTCACGGCGGCTCGATCGCCGCAGC
GTGCGCGATGCGGACCTGATTCTCGTCACCGAACAGCGGCAAGTAAAAGACGTGGAAGACCTCGAACCCACTTCGCGCGG
CAAGGTGTACTCGCTCGGCAAGTGGGACGCGTGCGGCAGCGCCGACGTCGTCGATCCGCACGGACGCGACGAAGCCGTGT
ATCGCGACAGCCTCGCGCACATCGAACACCTCGTCATGGGATGGCTGAACAAAATATGCTGA

Upstream 100 bases:

>100_bases
CAACGCACGCCGCACGACGCGGCCCCGTCGTTGACGACGCTGGCGACGGCCGCCGCGCTGTAACGCTGCAAGACCTCATC
GACCTGTACGGAGGCCGCCC

Downstream 100 bases:

>100_bases
AACGACACATCACGATATCTCTTGCGCTGACGACTTTTCTGTCGGCATGCGCGACCGCGCCGGGGAACTACCTCGACACG
TCGCGCCTGAAGGAAGACCA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MFANVLIVCHANVCRSPAAEWLFRSRQHGRGARPIAFRSAGLRAIDGHGMDPVMRRLLEERGVDGGTTGGHRSRRLDRRS
VRDADLILVTEQRQVKDVEDLEPTSRGKVYSLGKWDACGSADVVDPHGRDEAVYRDSLAHIEHLVMGWLNKIC

Sequences:

>Translated_153_residues
MFANVLIVCHANVCRSPAAEWLFRSRQHGRGARPIAFRSAGLRAIDGHGMDPVMRRLLEERGVDGGTTGGHRSRRLDRRS
VRDADLILVTEQRQVKDVEDLEPTSRGKVYSLGKWDACGSADVVDPHGRDEAVYRDSLAHIEHLVMGWLNKIC
>Mature_153_residues
MFANVLIVCHANVCRSPAAEWLFRSRQHGRGARPIAFRSAGLRAIDGHGMDPVMRRLLEERGVDGGTTGGHRSRRLDRRS
VRDADLILVTEQRQVKDVEDLEPTSRGKVYSLGKWDACGSADVVDPHGRDEAVYRDSLAHIEHLVMGWLNKIC

Specific function: Dephosphorylates ptk. May be involved in the production and the transport of exopolysaccharides [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=148, Percent_Identity=33.7837837837838, Blast_Score=85, Evalue=2e-18,
Organism=Escherichia coli, GI87081812, Length=151, Percent_Identity=27.1523178807947, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17126; Mature: 17126

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFANVLIVCHANVCRSPAAEWLFRSRQHGRGARPIAFRSAGLRAIDGHGMDPVMRRLLEE
CCCCEEEEECCHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHH
RGVDGGTTGGHRSRRLDRRSVRDADLILVTEQRQVKDVEDLEPTSRGKVYSLGKWDACGS
CCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHCCHHHCCCCCCCCEEECCCCCCCCC
ADVVDPHGRDEAVYRDSLAHIEHLVMGWLNKIC
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFANVLIVCHANVCRSPAAEWLFRSRQHGRGARPIAFRSAGLRAIDGHGMDPVMRRLLEE
CCCCEEEEECCHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCEEECCCCCCHHHHHHHHH
RGVDGGTTGGHRSRRLDRRSVRDADLILVTEQRQVKDVEDLEPTSRGKVYSLGKWDACGS
CCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHCCHHHCCCCCCCCEEECCCCCCCCC
ADVVDPHGRDEAVYRDSLAHIEHLVMGWLNKIC
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9434192; 9571056 [H]