Click here to switch to the map view.

The map label for this gene is bcd [H]

Identifier: 186475529

GI number: 186475529

Start: 860321

End: 862111

Strand: Direct

Name: bcd [H]

Synonym: Bphy_0764

Alternate gene names: 186475529

Gene position: 860321-862111 (Clockwise)

Preceding gene: 186475528

Following gene: 186475531

Centisome position: 24.73

GC content: 64.94

Gene sequence:

>1791_bases
ATGAGCTACGCGGCACCCATCAAGGACATGCTGTTCGTGATGCAGGAACTTGCCGGACTGGAAGACATGGCAGGCCTGCC
CGGCTTCGAAGAAGCGGGTCTGGAAACGGCGCAGGCCGTGCTGGAAGAATCGTCGAAGCTGTGCGGCGAAGTGCTGGCGC
CGCTGAACGTCGAAGGCGACCGGAATCCGAGCACGTGGAAAGACGGCAAGGTGACGGCGAGCCCCGGTTTCGCCGACGCG
TTTCGCCAGTTCGCCGCGGGCGGCTGGCAGGGCGTGCAGCATCCCGCCGAATACGAAGGCCAGGGCCTGCCGAAGCTGAT
CGGGACGGCTTGCATCGAGATGCTGAATGCGTCGAACCTGGCATTCGCGCTGTGTCCGCTGCTGACCGACGGCGCCATCG
AGGCGCTGCTCACCGCCGGCAGCGAAGAACAGAAACAGACCTACGTGCCGCGCCTGATCTCGGGCAACTGGACGGGCACG
ATGAACCTCACCGAGCCGCAGGCCGGCTCGGATCTCGCGCTGGTGCGCACGCGCGCCGAGCCGCAGGGCGACGGTTCGTA
CCGGATCTTCGGCACGAAGATCTTCATCACGTGGGGCGAGCACGACATGGCGGACAACATCGTCCACCTGGTGCTCGCGC
GTACGCCGGATGCGCCCGAAGGCGTGAAGGGCATTTCGCTGTTCGTGGTGCCCAAGTTCCTCGTCCATGCTGATGGCTCG
CTCGGTGAGCGCAACGACGTGCACTGCGTGTCGATCGAACACAAGCTCGGCATCAAGGCGAGCCCGACGGCCGTGCTGCA
GTTCGGCGACCACGGTGGCGCAATCGGTCACCTGATCGGCGAGGAAAATCGCGGCCTCGAATATATGTTCATCATGATGA
ACGCGGCGCGTTTCGCGGTCGGCATGCAGGGCGTGGCCATTTCGGATCGCGCATACCAGAAGGCGGCCGCGTACGCGAAG
GAGCGCGTGCAGAGCCGGCCCGTCGATGGTTCGTCGAAACAGGCGGTATCGATCATTCATCATCCGGACGTGCGTCGCAT
GCTGTCGACGATGCGTGCGCTCACGGAAGGTTCGCGCGCGCTGGCGTATGTGGCCGCGGCGCACAGCGACATCGCGCACC
ATCACGCGGATCAGGCGAAGCGTGCGGAGCATCTCGCGATCTACGAATACCTGGTGCCGATCGTAAAGGGCTGGAGCACG
GAGCTGTCGGTCGACGTGACGAGCCTGGGCGTGCAGGTGCATGGCGGCATGGGCTTCATCGAGGAAACGGGTGCCGCGCA
GTACTACCGCGACGCCCGTATCCTGCCGATCTACGAAGGCACGACGGCGATCCAGGCAAACGATCTGGTCGGCCGCAAGA
CGCTGCGCGACGGCGGCGCGGTGGCGAAGGCGCTGCTGGCGGACATCGCACAGACGGTCGAAGCACTCAAGCAGCACAAG
GGCGCAGCCTTCGCGTCAATGCAGAAGCATCTGTCGCGTGGGCATGACGCGTTGCAAACGACGGTGGCGTTCGTCGTCGC
GAATGCGAAGAGCGATCCGAACGCGGTGTTTGCGGGCAGCGTCGCATATCTGAAGCTCGCGGGAATCGTGCTGGGCGGCT
GGCAGATGGCGCGCGCGATGCTCGCCGCGCAGGCGAAGCTCGATAACGATCCGTCGTTCTATGGCGCGAAGATCGCGACG
GCCCAGTTCTTCGCGGAGCACGTGCTGCCGCAGGCCGTGGCGCTGGAGGCGTCGATTGTCAGCACGAAGGACGGCGAAGG
CATGCTGGCCTTGCGCGAAGACCAGTTCTGA

Upstream 100 bases:

>100_bases
GACTGACGCGCCGCCTGGCGGCGCGCGACACCGGCGGAAAGAGGCGCTAGGATGACGAATCCAGCGCCTCTTTTTTCTTT
GGGGGCGGAAGGAGACACAG

Downstream 100 bases:

>100_bases
CATCCCCGGTGCATCGAACAACAACGGCGCCCGAGGGCGCCGTTGTTTCGTCAACAAAATCCCATCGCGGAATCAGGCAT
AAGCCGGACGCGTCTGGCCT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 596; Mature: 595

Protein sequence:

>596_residues
MSYAAPIKDMLFVMQELAGLEDMAGLPGFEEAGLETAQAVLEESSKLCGEVLAPLNVEGDRNPSTWKDGKVTASPGFADA
FRQFAAGGWQGVQHPAEYEGQGLPKLIGTACIEMLNASNLAFALCPLLTDGAIEALLTAGSEEQKQTYVPRLISGNWTGT
MNLTEPQAGSDLALVRTRAEPQGDGSYRIFGTKIFITWGEHDMADNIVHLVLARTPDAPEGVKGISLFVVPKFLVHADGS
LGERNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGHLIGEENRGLEYMFIMMNAARFAVGMQGVAISDRAYQKAAAYAK
ERVQSRPVDGSSKQAVSIIHHPDVRRMLSTMRALTEGSRALAYVAAAHSDIAHHHADQAKRAEHLAIYEYLVPIVKGWST
ELSVDVTSLGVQVHGGMGFIEETGAAQYYRDARILPIYEGTTAIQANDLVGRKTLRDGGAVAKALLADIAQTVEALKQHK
GAAFASMQKHLSRGHDALQTTVAFVVANAKSDPNAVFAGSVAYLKLAGIVLGGWQMARAMLAAQAKLDNDPSFYGAKIAT
AQFFAEHVLPQAVALEASIVSTKDGEGMLALREDQF

Sequences:

>Translated_596_residues
MSYAAPIKDMLFVMQELAGLEDMAGLPGFEEAGLETAQAVLEESSKLCGEVLAPLNVEGDRNPSTWKDGKVTASPGFADA
FRQFAAGGWQGVQHPAEYEGQGLPKLIGTACIEMLNASNLAFALCPLLTDGAIEALLTAGSEEQKQTYVPRLISGNWTGT
MNLTEPQAGSDLALVRTRAEPQGDGSYRIFGTKIFITWGEHDMADNIVHLVLARTPDAPEGVKGISLFVVPKFLVHADGS
LGERNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGHLIGEENRGLEYMFIMMNAARFAVGMQGVAISDRAYQKAAAYAK
ERVQSRPVDGSSKQAVSIIHHPDVRRMLSTMRALTEGSRALAYVAAAHSDIAHHHADQAKRAEHLAIYEYLVPIVKGWST
ELSVDVTSLGVQVHGGMGFIEETGAAQYYRDARILPIYEGTTAIQANDLVGRKTLRDGGAVAKALLADIAQTVEALKQHK
GAAFASMQKHLSRGHDALQTTVAFVVANAKSDPNAVFAGSVAYLKLAGIVLGGWQMARAMLAAQAKLDNDPSFYGAKIAT
AQFFAEHVLPQAVALEASIVSTKDGEGMLALREDQF
>Mature_595_residues
SYAAPIKDMLFVMQELAGLEDMAGLPGFEEAGLETAQAVLEESSKLCGEVLAPLNVEGDRNPSTWKDGKVTASPGFADAF
RQFAAGGWQGVQHPAEYEGQGLPKLIGTACIEMLNASNLAFALCPLLTDGAIEALLTAGSEEQKQTYVPRLISGNWTGTM
NLTEPQAGSDLALVRTRAEPQGDGSYRIFGTKIFITWGEHDMADNIVHLVLARTPDAPEGVKGISLFVVPKFLVHADGSL
GERNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGHLIGEENRGLEYMFIMMNAARFAVGMQGVAISDRAYQKAAAYAKE
RVQSRPVDGSSKQAVSIIHHPDVRRMLSTMRALTEGSRALAYVAAAHSDIAHHHADQAKRAEHLAIYEYLVPIVKGWSTE
LSVDVTSLGVQVHGGMGFIEETGAAQYYRDARILPIYEGTTAIQANDLVGRKTLRDGGAVAKALLADIAQTVEALKQHKG
AAFASMQKHLSRGHDALQTTVAFVVANAKSDPNAVFAGSVAYLKLAGIVLGGWQMARAMLAAQAKLDNDPSFYGAKIATA
QFFAEHVLPQAVALEASIVSTKDGEGMLALREDQF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=320, Percent_Identity=28.75, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4501859, Length=405, Percent_Identity=26.6666666666667, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4557233, Length=310, Percent_Identity=30.9677419354839, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4557235, Length=388, Percent_Identity=28.3505154639175, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI76496475, Length=388, Percent_Identity=28.3505154639175, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958412, Length=416, Percent_Identity=25.9615384615385, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI21361497, Length=418, Percent_Identity=26.0765550239234, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=25.8855585831063, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI7656849, Length=387, Percent_Identity=26.6149870801034, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI187960098, Length=310, Percent_Identity=27.0967741935484, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4557231, Length=310, Percent_Identity=27.0967741935484, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI87082384, Length=351, Percent_Identity=29.6296296296296, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17506239, Length=433, Percent_Identity=27.2517321016166, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=27.1978021978022, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71985184, Length=425, Percent_Identity=28.4705882352941, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI86563383, Length=394, Percent_Identity=29.6954314720812, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI86563381, Length=394, Percent_Identity=29.6954314720812, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=367, Percent_Identity=28.3378746594005, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=427, Percent_Identity=27.1662763466042, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17570075, Length=389, Percent_Identity=24.6786632390745, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=26.9333333333333, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17533517, Length=370, Percent_Identity=25.9459459459459, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=410, Percent_Identity=26.3414634146341, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=299, Percent_Identity=28.7625418060201, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=30.672268907563, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=283, Percent_Identity=27.5618374558304, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551932, Length=366, Percent_Identity=25.9562841530055, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=242, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281363737, Length=361, Percent_Identity=27.4238227146814, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=27.9255319148936, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24660351, Length=354, Percent_Identity=29.9435028248588, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24666513, Length=415, Percent_Identity=25.5421686746988, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21355753, Length=429, Percent_Identity=27.039627039627, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24646207, Length=385, Percent_Identity=26.4935064935065, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 63702; Mature: 63571

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYAAPIKDMLFVMQELAGLEDMAGLPGFEEAGLETAQAVLEESSKLCGEVLAPLNVEGD
CCCCCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RNPSTWKDGKVTASPGFADAFRQFAAGGWQGVQHPAEYEGQGLPKLIGTACIEMLNASNL
CCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
AFALCPLLTDGAIEALLTAGSEEQKQTYVPRLISGNWTGTMNLTEPQAGSDLALVRTRAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCEEEEEECCCCCCCCEEEEEECCC
PQGDGSYRIFGTKIFITWGEHDMADNIVHLVLARTPDAPEGVKGISLFVVPKFLVHADGS
CCCCCCEEEEEEEEEEEECCCCHHHHHHEEHEECCCCCCCCCCCEEEEEEHHHHHCCCCC
LGERNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGHLIGEENRGLEYMFIMMNAARFAV
CCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEHEECCCCCCCEEEEEEEHHHHHHH
GMQGVAISDRAYQKAAAYAKERVQSRPVDGSSKQAVSIIHHPDVRRMLSTMRALTEGSRA
CCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHH
LAYVAAAHSDIAHHHADQAKRAEHLAIYEYLVPIVKGWSTELSVDVTSLGVQVHGGMGFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCH
EETGAAQYYRDARILPIYEGTTAIQANDLVGRKTLRDGGAVAKALLADIAQTVEALKQHK
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GAAFASMQKHLSRGHDALQTTVAFVVANAKSDPNAVFAGSVAYLKLAGIVLGGWQMARAM
CHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
LAAQAKLDNDPSFYGAKIATAQFFAEHVLPQAVALEASIVSTKDGEGMLALREDQF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHEEECCCCCCEEEEECCCC
>Mature Secondary Structure 
SYAAPIKDMLFVMQELAGLEDMAGLPGFEEAGLETAQAVLEESSKLCGEVLAPLNVEGD
CCCCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RNPSTWKDGKVTASPGFADAFRQFAAGGWQGVQHPAEYEGQGLPKLIGTACIEMLNASNL
CCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
AFALCPLLTDGAIEALLTAGSEEQKQTYVPRLISGNWTGTMNLTEPQAGSDLALVRTRAE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCEEEEEECCCCCCCCEEEEEECCC
PQGDGSYRIFGTKIFITWGEHDMADNIVHLVLARTPDAPEGVKGISLFVVPKFLVHADGS
CCCCCCEEEEEEEEEEEECCCCHHHHHHEEHEECCCCCCCCCCCEEEEEEHHHHHCCCCC
LGERNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGHLIGEENRGLEYMFIMMNAARFAV
CCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCEEHEECCCCCCCEEEEEEEHHHHHHH
GMQGVAISDRAYQKAAAYAKERVQSRPVDGSSKQAVSIIHHPDVRRMLSTMRALTEGSRA
CCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHH
LAYVAAAHSDIAHHHADQAKRAEHLAIYEYLVPIVKGWSTELSVDVTSLGVQVHGGMGFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCH
EETGAAQYYRDARILPIYEGTTAIQANDLVGRKTLRDGGAVAKALLADIAQTVEALKQHK
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GAAFASMQKHLSRGHDALQTTVAFVVANAKSDPNAVFAGSVAYLKLAGIVLGGWQMARAM
CHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHH
LAAQAKLDNDPSFYGAKIATAQFFAEHVLPQAVALEASIVSTKDGEGMLALREDQF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHEEECCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]