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The map label for this gene is etfA [H]

Identifier: 186475528

GI number: 186475528

Start: 859283

End: 860218

Strand: Direct

Name: etfA [H]

Synonym: Bphy_0763

Alternate gene names: 186475528

Gene position: 859283-860218 (Clockwise)

Preceding gene: 186475527

Following gene: 186475529

Centisome position: 24.7

GC content: 62.5

Gene sequence:

>936_bases
ATGACGATTCTGGTAATTGCTGAACACGACAACGCGTCGATCAAGGCTGCCACGCTGAATACGGTGGCGGCGGCACAGAA
GATCGGCGGTGATATCCACGTGCTGGTCGCAGGTCACAACGCGCAGGCTGCAGCCGATGCAGCGGCGAAGATCGCGGGTG
TCTCGAAAGTGCTGCTCGCCGATGCGCCGCAACTGGCCGAAGGCCTCGCTGAGAATGTCGAAGCGACCGTGCTGAACATC
GCGAAGGACTATTCGCACGTCCTCGCACCGGCCACGGCTTACGGCAAGAACATCGCGCCGCGTATCGCCGCAAAGCTGGA
CGTCGCGCAGATCAGCGACATCACGGCTGTCGATTCCGCCGATACGTTCGAGCGCCCGATCTACGCCGGCAATGCGATCG
CGATCGTGCAATCGGCTGATCCGATCAAGGTCATCACCGTGCGCGCAACGGGCTTCGATCCCGTGGCAGCCGAAGGCGGC
AGCGCATCGGTCGAAAAGATCGAAGCTGCGGCTGATAGCGGCATCTCGCAGTTCGTGAGCCGTGAAGTGACGAAGCTGGA
TCGTCCGGAACTGACGTCGGCGAACATCATCGTGTCGGGTGGCCGGGGCCTCGGCAGCGGCGAGAACTACACGAAAGTGC
TGGAGCCGCTCGCCGACAAGCTCGGCGCAGCGATGGGCGCGTCGCGTGCAGCCGTCGACGCTGGCTACGTGCCTAACGAC
TATCAGGTCGGCCAGACCGGCAAAATCGTCGCGCCCCAGCTCTACATCGCGGTCGGCATCTCAGGCGCGATCCAGCATCT
GGCGGGCATGAAGGACTCGAAGGTCATCGTCGCGATCAACAAGGACGAAGAAGCGCCGATTTTCAGCGTCGCGGATTACG
GTCTGGTTGGCGATCTCTTCACGGCGGTGCCGGATCTGGTGAAGGAACTCGGCTGA

Upstream 100 bases:

>100_bases
TTCGGCCGGCGTGAAGGTGGCCGACGTGAAGACGCTGGTCGAGAAGCTCAAGACGGAAGCCAAGGTGCTTTGATTTTTCG
GGCACACGGAGACGAATGAA

Downstream 100 bases:

>100_bases
CCGACTGACGCGCCGCCTGGCGGCGCGCGACACCGGCGGAAAGAGGCGCTAGGATGACGAATCCAGCGCCTCTTTTTTCT
TTGGGGGCGGAAGGAGACAC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQAAADAAAKIAGVSKVLLADAPQLAEGLAENVEATVLNI
AKDYSHVLAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIAIVQSADPIKVITVRATGFDPVAAEGG
SASVEKIEAAADSGISQFVSREVTKLDRPELTSANIIVSGGRGLGSGENYTKVLEPLADKLGAAMGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFSVADYGLVGDLFTAVPDLVKELG

Sequences:

>Translated_311_residues
MTILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQAAADAAAKIAGVSKVLLADAPQLAEGLAENVEATVLNI
AKDYSHVLAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIAIVQSADPIKVITVRATGFDPVAAEGG
SASVEKIEAAADSGISQFVSREVTKLDRPELTSANIIVSGGRGLGSGENYTKVLEPLADKLGAAMGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFSVADYGLVGDLFTAVPDLVKELG
>Mature_310_residues
TILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQAAADAAAKIAGVSKVLLADAPQLAEGLAENVEATVLNIA
KDYSHVLAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIAIVQSADPIKVITVRATGFDPVAAEGGS
ASVEKIEAAADSGISQFVSREVTKLDRPELTSANIIVSGGRGLGSGENYTKVLEPLADKLGAAMGASRAAVDAGYVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFSVADYGLVGDLFTAVPDLVKELG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=57.8778135048232, Blast_Score=346, Evalue=2e-95,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=58.9090909090909, Blast_Score=310, Evalue=1e-84,
Organism=Escherichia coli, GI1787990, Length=292, Percent_Identity=32.8767123287671, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786226, Length=234, Percent_Identity=35.8974358974359, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI87082157, Length=254, Percent_Identity=31.1023622047244, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=55.7692307692308, Blast_Score=334, Evalue=4e-92,
Organism=Saccharomyces cerevisiae, GI6325261, Length=318, Percent_Identity=43.3962264150943, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=60.5769230769231, Blast_Score=355, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=60.5769230769231, Blast_Score=355, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31730; Mature: 31599

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQAAADAAAKIAGVSKVLLA
CEEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
DAPQLAEGLAENVEATVLNIAKDYSHVLAPATAYGKNIAPRIAAKLDVAQISDITAVDSA
CCHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCHHHHCCCEECCCC
DTFERPIYAGNAIAIVQSADPIKVITVRATGFDPVAAEGGSASVEKIEAAADSGISQFVS
CHHCCCEECCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
REVTKLDRPELTSANIIVSGGRGLGSGENYTKVLEPLADKLGAAMGASRAAVDAGYVPND
HHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFSVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHH
TAVPDLVKELG
HHHHHHHHHCC
>Mature Secondary Structure 
TILVIAEHDNASIKAATLNTVAAAQKIGGDIHVLVAGHNAQAAADAAAKIAGVSKVLLA
EEEEEEECCCCEEEEEHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
DAPQLAEGLAENVEATVLNIAKDYSHVLAPATAYGKNIAPRIAAKLDVAQISDITAVDSA
CCHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCHHHHCCCEECCCC
DTFERPIYAGNAIAIVQSADPIKVITVRATGFDPVAAEGGSASVEKIEAAADSGISQFVS
CHHCCCEECCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
REVTKLDRPELTSANIIVSGGRGLGSGENYTKVLEPLADKLGAAMGASRAAVDAGYVPND
HHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFSVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHH
TAVPDLVKELG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]