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The map label for this gene is aroA

Identifier: 186475509

GI number: 186475509

Start: 840037

End: 841341

Strand: Direct

Name: aroA

Synonym: Bphy_0744

Alternate gene names: 186475509

Gene position: 840037-841341 (Clockwise)

Preceding gene: 186475508

Following gene: 186475510

Centisome position: 24.14

GC content: 65.13

Gene sequence:

>1305_bases
ATGGAACATCTCGATCTCGGACCATTTTCCCGTGCTTCCGGCACGGTTCGTCTGCCAGGCTCGAAGAGCATTTCGAACCG
CGTGCTGCTGCTCGCGGCGTTGGCCGAAGGCGAGACGACGATCACGAATCTGCTCGATTCCGACGACACGCGGGTGATGC
TCGACGCGCTCGAAAAGCTCGGCGTGAAGTTCAAGCGCGACGGCGACACCTGTGTCGTGACAGGCACGCGCGGCGCGCTG
CCTGCGGCGCGCGCGGACCTCTTTCTCGGGAACGCCGGCACGGCGGTGCGGCCGCTGACAGCGGCGCTCGCCGTGAATGG
CGGCGACTACCGGATTCACGGGGTGCCGCGCATGCACGAGCGGCCGATCGGCGATCTGGTCGACGGATTGCGGCAGATCG
GCGCGAAGATCGACTACGAAGAGAACGAAGGCTTCCCGCCGCTGCGCATCCGCCCGGCGCAGATTTCGGTCGACGCGCCC
ATCCGCGTGCGCGGCGACGTGTCGAGCCAGTTCCTGACGGCGCTGCTGATGACGCTGCCGCTCGTGAAGACGGAAAGCGG
CGAGACGATTGTCGAAGTGTCAGGCGAACTGATTTCCAAGCCGTACATCGAGATCACGATCCGGCTGATGGAACGCTTCG
GCATCAAGGTCGAGCGTTTCGGCTGGGAGCGCTTCACGATTCCGAGTGGCGTGCGTTATCAGTCGCCGGGCAAGATCATG
GTGGAAGGCGACGCATCGTCGGCGTCGTACTTCCTCGCGGCGGGCGCGCTGGGCGGGGGGCCGCTGCGGGTCGAAGGCGT
GGGGCGCGCGAGCATTCAGGGGGACGTCGGTTTCGCGACGGCGCTGATGAAGATGGGCGCGAACGTGACGATGGGGGACG
ACTGGATCGAAGTGCGCGGCGTGGGCAACGATCACGGAAAGCTGGACCCGATCGACATGGACTTCAACCTGATCCCCGAT
GCGGCGATGACCATCGCAGTGGCCGCGCTGTTCGCGGACGGCACGACCACGCTGCGCAATATCGGGAGCTGGCGCGTGAA
GGAAACGGATCGGATCGCCGCGATGGCGACGGAGTTGAGCAAGGTCGGCGCAAAGGTGCAGGCGGGTGAGGATTTTCTCG
TCGTGACGCCACCCGAGCAACTGACGCCGAACGCCGCGATCGACACCTACGACGACCACCGGATGGCGATGTGCTTCTCT
CTGGTGAGCCTCGGCGGCGTGCCCGTCCGGATCAACGATCCGAAATGCGTCGGCAAGACGTTCCCCGATTATTTCGAGCG
TTTCCTGGCGCTCACGCAACCCTGA

Upstream 100 bases:

>100_bases
CGCAGCGCCTGGCAGGAGCGCGCTGCGTCCGCACGTCAGGCATCGCCCGCACGTTCGGCCAACGACGAAGCGTCGAAATA
AAGGACCTTGGAATTCATAT

Downstream 100 bases:

>100_bases
CACCGCATTGCTAACCCGTGCCGCCCGTTCCGACGGACGACCTTTTCGATGAAACCGACCCGCCCCTTTCACCAGACGCC
CGTTATCACGATCGACGGCC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MEHLDLGPFSRASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALEKLGVKFKRDGDTCVVTGTRGAL
PAARADLFLGNAGTAVRPLTAALAVNGGDYRIHGVPRMHERPIGDLVDGLRQIGAKIDYEENEGFPPLRIRPAQISVDAP
IRVRGDVSSQFLTALLMTLPLVKTESGETIVEVSGELISKPYIEITIRLMERFGIKVERFGWERFTIPSGVRYQSPGKIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFATALMKMGANVTMGDDWIEVRGVGNDHGKLDPIDMDFNLIPD
AAMTIAVAALFADGTTTLRNIGSWRVKETDRIAAMATELSKVGAKVQAGEDFLVVTPPEQLTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFERFLALTQP

Sequences:

>Translated_434_residues
MEHLDLGPFSRASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALEKLGVKFKRDGDTCVVTGTRGAL
PAARADLFLGNAGTAVRPLTAALAVNGGDYRIHGVPRMHERPIGDLVDGLRQIGAKIDYEENEGFPPLRIRPAQISVDAP
IRVRGDVSSQFLTALLMTLPLVKTESGETIVEVSGELISKPYIEITIRLMERFGIKVERFGWERFTIPSGVRYQSPGKIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFATALMKMGANVTMGDDWIEVRGVGNDHGKLDPIDMDFNLIPD
AAMTIAVAALFADGTTTLRNIGSWRVKETDRIAAMATELSKVGAKVQAGEDFLVVTPPEQLTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFERFLALTQP
>Mature_434_residues
MEHLDLGPFSRASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALEKLGVKFKRDGDTCVVTGTRGAL
PAARADLFLGNAGTAVRPLTAALAVNGGDYRIHGVPRMHERPIGDLVDGLRQIGAKIDYEENEGFPPLRIRPAQISVDAP
IRVRGDVSSQFLTALLMTLPLVKTESGETIVEVSGELISKPYIEITIRLMERFGIKVERFGWERFTIPSGVRYQSPGKIM
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFATALMKMGANVTMGDDWIEVRGVGNDHGKLDPIDMDFNLIPD
AAMTIAVAALFADGTTTLRNIGSWRVKETDRIAAMATELSKVGAKVQAGEDFLVVTPPEQLTPNAAIDTYDDHRMAMCFS
LVSLGGVPVRINDPKCVGKTFPDYFERFLALTQP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=436, Percent_Identity=57.5688073394495, Blast_Score=466, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6320332, Length=450, Percent_Identity=40.2222222222222, Blast_Score=254, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_BURP8 (B2JF04)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001856979.1
- ProteinModelPortal:   B2JF04
- SMR:   B2JF04
- GeneID:   6242242
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_0744
- HOGENOM:   HBG646626
- OMA:   GADIEWG
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46632; Mature: 46632

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLDLGPFSRASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALEKL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHC
GVKFKRDGDTCVVTGTRGALPAARADLFLGNAGTAVRPLTAALAVNGGDYRIHGVPRMHE
CCEEEECCCEEEEECCCCCCCCCHHEEEECCCCCCHHHEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAKIDYEENEGFPPLRIRPAQISVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEECCCEEEECCCHHHHHHHHHHHHC
LVKTESGETIVEVSGELISKPYIEITIRLMERFGIKVERFGWERFTIPSGVRYQSPGKIM
CEECCCCCEEEEECHHHHCCCHHHHHHHHHHHHCCEEEEECCEEEECCCCCEECCCCEEE
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFATALMKMGANVTMGDDWIEVRG
EECCCCCCEEEEEECCCCCCCEEEEECCCEECCCCHHHHHHHHHCCCCEEECCCEEEEEE
VGNDHGKLDPIDMDFNLIPDAAMTIAVAALFADGTTTLRNIGSWRVKETDRIAAMATELS
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCHHHHHCCCEEECCHHHHHHHHHHHH
KVGAKVQAGEDFLVVTPPEQLTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKT
HHCCEEECCCCEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCC
FPDYFERFLALTQP
CHHHHHHHHHCCCC
>Mature Secondary Structure
MEHLDLGPFSRASGTVRLPGSKSISNRVLLLAALAEGETTITNLLDSDDTRVMLDALEKL
CCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHC
GVKFKRDGDTCVVTGTRGALPAARADLFLGNAGTAVRPLTAALAVNGGDYRIHGVPRMHE
CCEEEECCCEEEEECCCCCCCCCHHEEEECCCCCCHHHEEEEEEECCCCEEEECCCCHHC
RPIGDLVDGLRQIGAKIDYEENEGFPPLRIRPAQISVDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCEEEECCCEEEECCCHHHHHHHHHHHHC
LVKTESGETIVEVSGELISKPYIEITIRLMERFGIKVERFGWERFTIPSGVRYQSPGKIM
CEECCCCCEEEEECHHHHCCCHHHHHHHHHHHHCCEEEEECCEEEECCCCCEECCCCEEE
VEGDASSASYFLAAGALGGGPLRVEGVGRASIQGDVGFATALMKMGANVTMGDDWIEVRG
EECCCCCCEEEEEECCCCCCCEEEEECCCEECCCCHHHHHHHHHCCCCEEECCCEEEEEE
VGNDHGKLDPIDMDFNLIPDAAMTIAVAALFADGTTTLRNIGSWRVKETDRIAAMATELS
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCHHHHHCCCEEECCHHHHHHHHHHHH
KVGAKVQAGEDFLVVTPPEQLTPNAAIDTYDDHRMAMCFSLVSLGGVPVRINDPKCVGKT
HHCCEEECCCCEEEECCCHHCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCC
FPDYFERFLALTQP
CHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA