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The map label for this gene is hisC1 [H]

Identifier: 186475507

GI number: 186475507

Start: 837889

End: 839004

Strand: Direct

Name: hisC1 [H]

Synonym: Bphy_0742

Alternate gene names: 186475507

Gene position: 837889-839004 (Clockwise)

Preceding gene: 186475506

Following gene: 186475508

Centisome position: 24.08

GC content: 63.08

Gene sequence:

>1116_bases
ATGACAACGTCGTCTTTCGGTCCCTCCTACGTTCGCGCGATCGCGCCCTATGTGGCTGGCAAGCCGATCTCGGAAGTCGC
ACGCGAATTCGGGCTGGACGAAGCGCGTATCGTGAAGCTGGCGTCGAACGAAAATCCGCTCGGCATGCCCGAGTCCGCGA
AGACGGCGATGGCGCAGGCTGCAAGCGAACTCAGCCGCTATCCGGATGCCAACGCATTCGAACTGAAGGCCGCGCTCTCC
GCGCATTACGACGTGCCCGCCGACTGGATCACGCTCGGCAACGGCAGCAACGACATTCTCGAACTGGCCGCGCACGCGTT
CGTCGAGAAGAGCCAGTCGGTGATCTACGCGCAATATTCTTTCGCCGTGTACGCGCTGGCGACGCAGGGACTGGGCGCGC
GCGCGATCGTCGTGCCCGCCGTCGGATACGGTCACGATCTCGACGCAATGCTCGCCGCGATCACTGACGACACGCGCCTC
GTTTTCGTCGCAAATCCGAACAATCCGACGGGCACGTTCATCGACGGCGCGACGATCGAAGCATTCCTGGCGAAGGTGCC
GCGCAGCGTCGTGGTGGTACTCGACGAGGCGTACACGGAATATCTGGCCGCCGACAAGCGCTATGACTCGATCGCGTGGG
TGCGCCGTTATCCGAATCTGCTGGTGTCGCGCACGTTCTCGAAGGCGTTCGGTCTCGCGGGGCTGCGCGTTGGTTTCGCG
ATTGCGCAGCCGGAACTGACGGATCTGATGAACCGTCTGCGTCAGCCGTTCAATGTGAACACGCTGGCGCAAGCCGCCGC
GGTCGCCGCGCTGAACGACAAGCGGTTCCTGCAGAAAAGCGCGGAATTGAATGCGCAGGGCTATCGCCGCCTGACGGAAG
CGTTCGACAAACTCGGTCTCGAGTACGTGCCCTCGTACGGCAACTTCGTGCTGGTGCGCGTCGGCCATGACGATGCGGCC
GGCAACCGCGTCAATCTGGAACTGCTGAAGCAGGGCGTGATCGTGCGACCCGTGGGAAGCTACGGTCTGCCGCAGTGGTT
GCGCGTGACGATCGGCCTGCCCGAAGAAAATGAAGCGTTTATCGCGGCGCTCGAAAAGACCCTGGCGACGGCCTGA

Upstream 100 bases:

>100_bases
CTCGTATCCGCGCGCCCGCTGACACACGGCTCGCATTCGTTTCGCAATCACGCAACCCGCGCAACCAACAAGAAGCCTGA
CAGCTATCCGGAGCTTTTCC

Downstream 100 bases:

>100_bases
GCGGATCCATGCAATCCATGCGCCTCATCGACTACGAGGCGCTTTTTTCTGTGACTGACGTGGCAGCGTTCTCTTTCGAC
AAACTGGTGATTTTTGGCGT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTTSSFGPSYVRAIAPYVAGKPISEVAREFGLDEARIVKLASNENPLGMPESAKTAMAQAASELSRYPDANAFELKAALS
AHYDVPADWITLGNGSNDILELAAHAFVEKSQSVIYAQYSFAVYALATQGLGARAIVVPAVGYGHDLDAMLAAITDDTRL
VFVANPNNPTGTFIDGATIEAFLAKVPRSVVVVLDEAYTEYLAADKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFA
IAQPELTDLMNRLRQPFNVNTLAQAAAVAALNDKRFLQKSAELNAQGYRRLTEAFDKLGLEYVPSYGNFVLVRVGHDDAA
GNRVNLELLKQGVIVRPVGSYGLPQWLRVTIGLPEENEAFIAALEKTLATA

Sequences:

>Translated_371_residues
MTTSSFGPSYVRAIAPYVAGKPISEVAREFGLDEARIVKLASNENPLGMPESAKTAMAQAASELSRYPDANAFELKAALS
AHYDVPADWITLGNGSNDILELAAHAFVEKSQSVIYAQYSFAVYALATQGLGARAIVVPAVGYGHDLDAMLAAITDDTRL
VFVANPNNPTGTFIDGATIEAFLAKVPRSVVVVLDEAYTEYLAADKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFA
IAQPELTDLMNRLRQPFNVNTLAQAAAVAALNDKRFLQKSAELNAQGYRRLTEAFDKLGLEYVPSYGNFVLVRVGHDDAA
GNRVNLELLKQGVIVRPVGSYGLPQWLRVTIGLPEENEAFIAALEKTLATA
>Mature_370_residues
TTSSFGPSYVRAIAPYVAGKPISEVAREFGLDEARIVKLASNENPLGMPESAKTAMAQAASELSRYPDANAFELKAALSA
HYDVPADWITLGNGSNDILELAAHAFVEKSQSVIYAQYSFAVYALATQGLGARAIVVPAVGYGHDLDAMLAAITDDTRLV
FVANPNNPTGTFIDGATIEAFLAKVPRSVVVVLDEAYTEYLAADKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFAI
AQPELTDLMNRLRQPFNVNTLAQAAAVAALNDKRFLQKSAELNAQGYRRLTEAFDKLGLEYVPSYGNFVLVRVGHDDAAG
NRVNLELLKQGVIVRPVGSYGLPQWLRVTIGLPEENEAFIAALEKTLATA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=371, Percent_Identity=26.9541778975741, Blast_Score=117, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6322075, Length=360, Percent_Identity=29.7222222222222, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40137; Mature: 40006

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSSFGPSYVRAIAPYVAGKPISEVAREFGLDEARIVKLASNENPLGMPESAKTAMAQA
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHEEEEEECCCCCCCCCHHHHHHHHHH
ASELSRYPDANAFELKAALSAHYDVPADWITLGNGSNDILELAAHAFVEKSQSVIYAQYS
HHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEHH
FAVYALATQGLGARAIVVPAVGYGHDLDAMLAAITDDTRLVFVANPNNPTGTFIDGATIE
HEEEEEHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCEECCHHHH
AFLAKVPRSVVVVLDEAYTEYLAADKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFA
HHHHHCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEE
IAQPELTDLMNRLRQPFNVNTLAQAAAVAALNDKRFLQKSAELNAQGYRRLTEAFDKLGL
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHCCC
EYVPSYGNFVLVRVGHDDAAGNRVNLELLKQGVIVRPVGSYGLPQWLRVTIGLPEENEAF
EECCCCCCEEEEEECCCCCCCCEEEHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCHH
IAALEKTLATA
HHHHHHHHHCC
>Mature Secondary Structure 
TTSSFGPSYVRAIAPYVAGKPISEVAREFGLDEARIVKLASNENPLGMPESAKTAMAQA
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHEEEEEECCCCCCCCCHHHHHHHHHH
ASELSRYPDANAFELKAALSAHYDVPADWITLGNGSNDILELAAHAFVEKSQSVIYAQYS
HHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEEHH
FAVYALATQGLGARAIVVPAVGYGHDLDAMLAAITDDTRLVFVANPNNPTGTFIDGATIE
HEEEEEHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCEECCHHHH
AFLAKVPRSVVVVLDEAYTEYLAADKRYDSIAWVRRYPNLLVSRTFSKAFGLAGLRVGFA
HHHHHCCCEEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEE
IAQPELTDLMNRLRQPFNVNTLAQAAAVAALNDKRFLQKSAELNAQGYRRLTEAFDKLGL
ECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHCCC
EYVPSYGNFVLVRVGHDDAAGNRVNLELLKQGVIVRPVGSYGLPQWLRVTIGLPEENEAF
EECCCCCCEEEEEECCCCCCCCEEEHHHHHCCCEEEECCCCCCCCEEEEEECCCCCCCHH
IAALEKTLATA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA