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The map label for this gene is pheA [H]

Identifier: 186475506

GI number: 186475506

Start: 836728

End: 837810

Strand: Direct

Name: pheA [H]

Synonym: Bphy_0741

Alternate gene names: 186475506

Gene position: 836728-837810 (Clockwise)

Preceding gene: 186475505

Following gene: 186475507

Centisome position: 24.05

GC content: 64.82

Gene sequence:

>1083_bases
ATGGACGACGAACTCAATTCTCAACTCAAACCGCTGCGCGAACGTATCGACGCGATCGACGCGCAGCTCATTGCGCTGCT
GAATCAACGCGCGGCGGTCGCGCTCGAAGTCGGCGAGGTGAAGAAGCACTTCAACGCGCCCGTGTTTCGTCCGGAGCGCG
AGCAACAGGTCATCGCGCGTCTGCAGGAGATGAGCGAAGGTCCGCTCGCAGGCGAACACATCAGCGCGATCTGGCGCGAG
ATCATGGCCGCGAGCCGCGCGCTCGAAAAGAACATCACGGCTGCCTACCTCGGGCCGGCTGGCACGTATAGCGAACAGGC
GATGCACGAATACTTCGGTCAGTCGATCGAAGGCCTGCCGTGTTCGTCCATCGACGAGGTGTTCCGTTCGGTCGAAGCGG
GCGGCGCGGAGTTCGGCGTCGTGCCCATCGAGAATTCGACGGAAGGCGCAGTCTCGCGCACGCTGGATCTTTTGCTGCAA
ACCCAGTTGCTGATCGGCGGCGAACTGGCTCTGCCCATCCACCACAATCTGCTGACGCTCAATGGCGGCCTGACGGGCGT
GACACGCGTATGCGCGCATGCGCAGGCACTCGCGCAGTGCCAGCGCTGGCTCGCGACGCACGCGCCGCATATCGAGCGCC
AGGCGGTATCGAGCAATGCCGAAGCCGCGCGCATGGCGGCCGACGATCCAACCATCGCCGCCATCGCCGGCGACCGCGCC
GCGACCCAGTACGGGTTGCAGGTCGCTCACGCGCTGATCCAGGACGATCCGCACAACCGCACGCGCTTCGTGATGATCGG
CAAACAGCCGACAGGTGCCAGCGGCTATGACAAGACCTCGCTGATCGTGTCGGTGGCGAACGAGCCGGGCGCGATGTTCA
AGCTGCTGGAGCCGCTCGCGAAGCACGGCGTGTCGATGACGCGCTTCGAGTCGCGTCCCGCGCGAGTCGGCACGTGGGAG
TACTACTTTTACATCGACCTCGAAGGCCATCGCGACGACGCATCCGTGTCCGCCGCGCTCGCCGAACTCGGCCAGAAGGC
CGACTTCCTGAAGATTCTCGGCTCGTATCCGCGCGCCCGCTGA

Upstream 100 bases:

>100_bases
GAGGGAATTCGAACAGCGCGGCGCGTGATCTTACTGGTTGCGGTGCGCGCATCCTCTCCGAACCGGGCCCTGGCTGGACC
CGAATTGGCCCTTTAGAAGC

Downstream 100 bases:

>100_bases
CACACGGCTCGCATTCGTTTCGCAATCACGCAACCCGCGCAACCAACAAGAAGCCTGACAGCTATCCGGAGCTTTTCCAT
GACAACGTCGTCTTTCGGTC

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MDDELNSQLKPLRERIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIARLQEMSEGPLAGEHISAIWRE
IMAASRALEKNITAAYLGPAGTYSEQAMHEYFGQSIEGLPCSSIDEVFRSVEAGGAEFGVVPIENSTEGAVSRTLDLLLQ
TQLLIGGELALPIHHNLLTLNGGLTGVTRVCAHAQALAQCQRWLATHAPHIERQAVSSNAEAARMAADDPTIAAIAGDRA
ATQYGLQVAHALIQDDPHNRTRFVMIGKQPTGASGYDKTSLIVSVANEPGAMFKLLEPLAKHGVSMTRFESRPARVGTWE
YYFYIDLEGHRDDASVSAALAELGQKADFLKILGSYPRAR

Sequences:

>Translated_360_residues
MDDELNSQLKPLRERIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIARLQEMSEGPLAGEHISAIWRE
IMAASRALEKNITAAYLGPAGTYSEQAMHEYFGQSIEGLPCSSIDEVFRSVEAGGAEFGVVPIENSTEGAVSRTLDLLLQ
TQLLIGGELALPIHHNLLTLNGGLTGVTRVCAHAQALAQCQRWLATHAPHIERQAVSSNAEAARMAADDPTIAAIAGDRA
ATQYGLQVAHALIQDDPHNRTRFVMIGKQPTGASGYDKTSLIVSVANEPGAMFKLLEPLAKHGVSMTRFESRPARVGTWE
YYFYIDLEGHRDDASVSAALAELGQKADFLKILGSYPRAR
>Mature_360_residues
MDDELNSQLKPLRERIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIARLQEMSEGPLAGEHISAIWRE
IMAASRALEKNITAAYLGPAGTYSEQAMHEYFGQSIEGLPCSSIDEVFRSVEAGGAEFGVVPIENSTEGAVSRTLDLLLQ
TQLLIGGELALPIHHNLLTLNGGLTGVTRVCAHAQALAQCQRWLATHAPHIERQAVSSNAEAARMAADDPTIAAIAGDRA
ATQYGLQVAHALIQDDPHNRTRFVMIGKQPTGASGYDKTSLIVSVANEPGAMFKLLEPLAKHGVSMTRFESRPARVGTWE
YYFYIDLEGHRDDASVSAALAELGQKADFLKILGSYPRAR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=372, Percent_Identity=34.1397849462366, Blast_Score=195, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324013, Length=324, Percent_Identity=24.6913580246914, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39140; Mature: 39140

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDELNSQLKPLRERIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCCCCCHHHHHHHH
LQEMSEGPLAGEHISAIWREIMAASRALEKNITAAYLGPAGTYSEQAMHEYFGQSIEGLP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCC
CSSIDEVFRSVEAGGAEFGVVPIENSTEGAVSRTLDLLLQTQLLIGGELALPIHHNLLTL
CCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEE
NGGLTGVTRVCAHAQALAQCQRWLATHAPHIERQAVSSNAEAARMAADDPTIAAIAGDRA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCCCCCEEEEECCHH
ATQYGLQVAHALIQDDPHNRTRFVMIGKQPTGASGYDKTSLIVSVANEPGAMFKLLEPLA
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KHGVSMTRFESRPARVGTWEYYFYIDLEGHRDDASVSAALAELGQKADFLKILGSYPRAR
HCCCEEEHHCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MDDELNSQLKPLRERIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCCCCCHHHHHHHH
LQEMSEGPLAGEHISAIWREIMAASRALEKNITAAYLGPAGTYSEQAMHEYFGQSIEGLP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCC
CSSIDEVFRSVEAGGAEFGVVPIENSTEGAVSRTLDLLLQTQLLIGGELALPIHHNLLTL
CCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCEEEE
NGGLTGVTRVCAHAQALAQCQRWLATHAPHIERQAVSSNAEAARMAADDPTIAAIAGDRA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCCCCCEEEEECCHH
ATQYGLQVAHALIQDDPHNRTRFVMIGKQPTGASGYDKTSLIVSVANEPGAMFKLLEPLA
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
KHGVSMTRFESRPARVGTWEYYFYIDLEGHRDDASVSAALAELGQKADFLKILGSYPRAR
HCCCEEEHHCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]