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The map label for this gene is rsmB [H]

Identifier: 186475344

GI number: 186475344

Start: 654461

End: 655720

Strand: Direct

Name: rsmB [H]

Synonym: Bphy_0577

Alternate gene names: 186475344

Gene position: 654461-655720 (Clockwise)

Preceding gene: 186475343

Following gene: 186475345

Centisome position: 18.81

GC content: 65.63

Gene sequence:

>1260_bases
ATGAGACTGCATGGATTTTTGATCGGACAAACCGAGACTTTGCTCGCGGACGTCCTAAAGTTCACCGGTCCCGCCGATGC
CGCGACCAGCCGCTTCTTCCGCGCGCATCCGAAGCTCGGCCACGGCGAGCGCGGCGTGATCGCGGAAGCGGTGTTCGCGG
TGCTCCGTCGCCGGATGGAATTTGCGCATCTGGCGGAAAGCGGCGCTGGTAGTCCGAACCGGCGCCTTGCGCTGCTTGGA
CTGATGCAGACGGCGGGCCGTACGGCGCTGAAGCCGTTCGTGTCGGAAGCAGAAAACGTTTGGCTGGAGCATGTCGCGAA
GATCGATCCGCAGAGCCTGCCGCTGCGAATCCGCATGAATCTGCCCGACTGGATCTATCAGGCGCTCAGCAACCGCTTCG
AAGCCGAGGAACTCGCGCATCTCGCCGCCGCGCTGAACTACCCGGCGCCGCTCGATCTGCGCGCGAACCCGATCAAGGCG
AGCCGCGACGACGTGCTGGGCGTGCTGTCGAAGGCGGCGATCGAAGCGGCTGCGACGCCTTACGCGCCGCTCGGTATCCG
GGTGGTCGGCAAGCCGCCTCTTACGAAGCTCGACGCGTTTCAGAGCGGCTGGCTCGAAGTGCAGGACGAAGGCAGCCAGC
TGCTGTGTTCGCTGGTCGCGCCCAAGCGCGGCGAGATGATCGTTGACTTTTGCGCGGGCGCGGGCGGCAAGACGCTGGCG
CTCGGCGCGATGATGCGTTCGACGGGTCGCCTGTACGCATTCGACATTTCCGAGCGGCGCCTCGCCAAGCTCAAGCCGCG
CCTCGCGCGCAGCGGCCTGTCGAATGTGAATCCCGTGCTGATCGACAGCGAGCACGACGCGAAGATCAAGCGGCTCGCGG
GCAAGATCGACCGTGTGTTGGTCGACGCGCCCTGCAGCGGCCTCGGCACGCTGCGCCGCAATCCGGATCTGAAATGGCGC
CAGTCGCCGGAATCGATCGCCGAGCTGACGCCCAAGCAGCTGTCGATCCTGACGAGCGCCGCGCGTCTCGTGAAGAAGGG
CGGACGGCTCGTGTATGCGACCTGCAGCATTCTCGACGCGGAAAACGAAGGGGTCGTGCAGCAGTTTCTCGCCGCTCACT
CCGATTTCGAACTCGTGCCCGCGCGTGACGTGCTCGCCGAGCAGCGCATCGATCTGGAAATGGGCGACTTTCTGTCGCTG
TGGCCGCACCGTCATTCGACGGACGGCTTCTTCGCGGCCGTGCTGGAGCGCCGCGGCTAG

Upstream 100 bases:

>100_bases
GGCGTCTCGCCGTCGACGGTCTGCGCGTCACCGTGACGCCGCCTGAGCCTCAGTGGCTTTTCCTTGATACAACAAGCAAG
TACAACGCCGGGGAGGGCGC

Downstream 100 bases:

>100_bases
AGGTATCCCGCCAATGGCCGGACTTCGCGCGGTCCGGCCGGCGCACGCCGCGTAAGCGGCGCGGCGCGCCGGCTGCTGGA
AATATCATGCAAAACCATCT

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRLHGFLIGQTETLLADVLKFTGPADAATSRFFRAHPKLGHGERGVIAEAVFAVLRRRMEFAHLAESGAGSPNRRLALLG
LMQTAGRTALKPFVSEAENVWLEHVAKIDPQSLPLRIRMNLPDWIYQALSNRFEAEELAHLAAALNYPAPLDLRANPIKA
SRDDVLGVLSKAAIEAAATPYAPLGIRVVGKPPLTKLDAFQSGWLEVQDEGSQLLCSLVAPKRGEMIVDFCAGAGGKTLA
LGAMMRSTGRLYAFDISERRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QSPESIAELTPKQLSILTSAARLVKKGGRLVYATCSILDAENEGVVQQFLAAHSDFELVPARDVLAEQRIDLEMGDFLSL
WPHRHSTDGFFAAVLERRG

Sequences:

>Translated_419_residues
MRLHGFLIGQTETLLADVLKFTGPADAATSRFFRAHPKLGHGERGVIAEAVFAVLRRRMEFAHLAESGAGSPNRRLALLG
LMQTAGRTALKPFVSEAENVWLEHVAKIDPQSLPLRIRMNLPDWIYQALSNRFEAEELAHLAAALNYPAPLDLRANPIKA
SRDDVLGVLSKAAIEAAATPYAPLGIRVVGKPPLTKLDAFQSGWLEVQDEGSQLLCSLVAPKRGEMIVDFCAGAGGKTLA
LGAMMRSTGRLYAFDISERRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QSPESIAELTPKQLSILTSAARLVKKGGRLVYATCSILDAENEGVVQQFLAAHSDFELVPARDVLAEQRIDLEMGDFLSL
WPHRHSTDGFFAAVLERRG
>Mature_419_residues
MRLHGFLIGQTETLLADVLKFTGPADAATSRFFRAHPKLGHGERGVIAEAVFAVLRRRMEFAHLAESGAGSPNRRLALLG
LMQTAGRTALKPFVSEAENVWLEHVAKIDPQSLPLRIRMNLPDWIYQALSNRFEAEELAHLAAALNYPAPLDLRANPIKA
SRDDVLGVLSKAAIEAAATPYAPLGIRVVGKPPLTKLDAFQSGWLEVQDEGSQLLCSLVAPKRGEMIVDFCAGAGGKTLA
LGAMMRSTGRLYAFDISERRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QSPESIAELTPKQLSILTSAARLVKKGGRLVYATCSILDAENEGVVQQFLAAHSDFELVPARDVLAEQRIDLEMGDFLSL
WPHRHSTDGFFAAVLERRG

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=318, Percent_Identity=30.5031446540881, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI76150623, Length=318, Percent_Identity=30.5031446540881, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI32698918, Length=223, Percent_Identity=30.9417040358744, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI23199998, Length=242, Percent_Identity=29.7520661157025, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI270288818, Length=242, Percent_Identity=29.7520661157025, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI8922322, Length=310, Percent_Identity=27.4193548387097, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI270288816, Length=310, Percent_Identity=27.4193548387097, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI301336155, Length=201, Percent_Identity=31.8407960199005, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI39995082, Length=201, Percent_Identity=31.8407960199005, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40316918, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=307, Percent_Identity=31.9218241042345, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI87081985, Length=286, Percent_Identity=29.3706293706294, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=295, Percent_Identity=30.5084745762712, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25143471, Length=326, Percent_Identity=27.3006134969325, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534021, Length=221, Percent_Identity=31.2217194570136, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71998419, Length=221, Percent_Identity=31.2217194570136, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=311, Percent_Identity=26.3665594855305, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319447, Length=243, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI22024126, Length=314, Percent_Identity=26.7515923566879, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356579, Length=298, Percent_Identity=26.8456375838926, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355201, Length=296, Percent_Identity=26.0135135135135, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356513, Length=192, Percent_Identity=30.2083333333333, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668781, Length=192, Percent_Identity=30.2083333333333, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19920494, Length=157, Percent_Identity=33.1210191082803, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 45794; Mature: 45794

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLHGFLIGQTETLLADVLKFTGPADAATSRFFRAHPKLGHGERGVIAEAVFAVLRRRME
CCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
FAHLAESGAGSPNRRLALLGLMQTAGRTALKPFVSEAENVWLEHVAKIDPQSLPLRIRMN
HHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
LPDWIYQALSNRFEAEELAHLAAALNYPAPLDLRANPIKASRDDVLGVLSKAAIEAAATP
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
YAPLGIRVVGKPPLTKLDAFQSGWLEVQDEGSQLLCSLVAPKRGEMIVDFCAGAGGKTLA
CCCCCEEEECCCCCHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
LGAMMRSTGRLYAFDISERRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQSPESIAELTPKQLSILTSAARLVKKGGRLVYATCSILDA
EECCCCCCHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
ENEGVVQQFLAAHSDFELVPARDVLAEQRIDLEMGDFLSLWPHRHSTDGFFAAVLERRG
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MRLHGFLIGQTETLLADVLKFTGPADAATSRFFRAHPKLGHGERGVIAEAVFAVLRRRME
CCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
FAHLAESGAGSPNRRLALLGLMQTAGRTALKPFVSEAENVWLEHVAKIDPQSLPLRIRMN
HHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
LPDWIYQALSNRFEAEELAHLAAALNYPAPLDLRANPIKASRDDVLGVLSKAAIEAAATP
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
YAPLGIRVVGKPPLTKLDAFQSGWLEVQDEGSQLLCSLVAPKRGEMIVDFCAGAGGKTLA
CCCCCEEEECCCCCHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
LGAMMRSTGRLYAFDISERRLAKLKPRLARSGLSNVNPVLIDSEHDAKIKRLAGKIDRVL
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHEE
VDAPCSGLGTLRRNPDLKWRQSPESIAELTPKQLSILTSAARLVKKGGRLVYATCSILDA
EECCCCCCHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECC
ENEGVVQQFLAAHSDFELVPARDVLAEQRIDLEMGDFLSLWPHRHSTDGFFAAVLERRG
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]