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The map label for this gene is xerD [H]

Identifier: 186475291

GI number: 186475291

Start: 594612

End: 595559

Strand: Direct

Name: xerD [H]

Synonym: Bphy_0523

Alternate gene names: 186475291

Gene position: 594612-595559 (Clockwise)

Preceding gene: 186475290

Following gene: 186475293

Centisome position: 17.09

GC content: 66.46

Gene sequence:

>948_bases
ATGACTGATGTGCTGACCGAAGACGCGCAGCCCGCGTCGCCTGCTGTTTCGCCGCTGCTGCTGACGAGCGGCGCGTCGAT
CGATGCCTTCTGCGATGCGCTATGGCTCGAACATGGCCTCGCGCGCAACACGCTCGACGCATACCGACGCGACTTGCGGC
TCTTTTCCGAATGGCTCGCCGAGCGGCGCGACGCTTCTCTCGATGCCGCGAGCGAAGCCGATCTGACGGCCTATAGCGCC
GCGCGCTCGGCCGACAAGTCGACCTCCGCGAACCGGCGTCTGTCTGTGTTTCGCCGCTACTATGCGTGGGCCGTGCGCGA
GCATCGCGCGTCAGCGGATCCAACCTTGCGCATCCGTTCGGCCAAGCAGCCGCCGCGTTTCCCGTCGACCTTGACGGAAG
CGCAGGTCGAAGCGCTGCTCGGGGCGCCGGACGTGACGACGCCGCTCGGCCTGCGCGACCGCACGATGCTCGAACTGATG
TACGCGAGCGGCTTGCGCGTCAGCGAACTGGTCACGTTGAAGACGGTGGAGGTCGGGCTGAACGAGGGCGTCGTGCGCGT
GATGGGCAAGGGCTCGAAAGAGCGGCTGATACCGTTCGGCGAAGAGGCGCACGCCTGGATTGAACGCTATCTGCGCGAGT
CTCGCCCCGCATTGCTCGGCCAGCGTTCCGCTGATGCGCTGTTCGTCACCGCGCGCGCCGAAGGCATGACGCGCCAGCAG
TTCTGGAACATCATCAAGCGTCATGCGCTGACGGCGCATGTGCACGCGCCCCTGTCACCGCACACGCTGCGGCACGCGTT
CGCGACGCATCTGCTGAATCACGGCGCGGACCTGCGTGTCGTGCAGCTGCTGCTCGGCCACACCGATATCTCGACCACGC
AGATTTACACGCACGTCGCACGTGAGCGGCTCAAGTCGCTGCACGCGGCTCACCATCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TCGCATCGGGCGGCATCGGCGGCTTTGCGCATACGGGCGGCGACGGCTACTATCGCAACGTCAAACGCTGGCTACTGAAA
CACGAGGGCGTACCTTACGC

Downstream 100 bases:

>100_bases
ATTTCCGGATCCGATTCGCGCGAGTCAGATGAGATCGCGCAGCCGGTGCTTGAGTATCTTGCCCGTCGAGGCCGCCGGTA
ATGCAGCGAGCACCCTGATT

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTDVLTEDAQPASPAVSPLLLTSGASIDAFCDALWLEHGLARNTLDAYRRDLRLFSEWLAERRDASLDAASEADLTAYSA
ARSADKSTSANRRLSVFRRYYAWAVREHRASADPTLRIRSAKQPPRFPSTLTEAQVEALLGAPDVTTPLGLRDRTMLELM
YASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLIPFGEEAHAWIERYLRESRPALLGQRSADALFVTARAEGMTRQQ
FWNIIKRHALTAHVHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHTDISTTQIYTHVARERLKSLHAAHHPRG

Sequences:

>Translated_315_residues
MTDVLTEDAQPASPAVSPLLLTSGASIDAFCDALWLEHGLARNTLDAYRRDLRLFSEWLAERRDASLDAASEADLTAYSA
ARSADKSTSANRRLSVFRRYYAWAVREHRASADPTLRIRSAKQPPRFPSTLTEAQVEALLGAPDVTTPLGLRDRTMLELM
YASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLIPFGEEAHAWIERYLRESRPALLGQRSADALFVTARAEGMTRQQ
FWNIIKRHALTAHVHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHTDISTTQIYTHVARERLKSLHAAHHPRG
>Mature_314_residues
TDVLTEDAQPASPAVSPLLLTSGASIDAFCDALWLEHGLARNTLDAYRRDLRLFSEWLAERRDASLDAASEADLTAYSAA
RSADKSTSANRRLSVFRRYYAWAVREHRASADPTLRIRSAKQPPRFPSTLTEAQVEALLGAPDVTTPLGLRDRTMLELMY
ASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLIPFGEEAHAWIERYLRESRPALLGQRSADALFVTARAEGMTRQQF
WNIIKRHALTAHVHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHTDISTTQIYTHVARERLKSLHAAHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=56.8027210884354, Blast_Score=314, Evalue=5e-87,
Organism=Escherichia coli, GI1790244, Length=299, Percent_Identity=38.4615384615385, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=29.0697674418605, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35069; Mature: 34938

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVLTEDAQPASPAVSPLLLTSGASIDAFCDALWLEHGLARNTLDAYRRDLRLFSEWLA
CCCCCCCCCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRDASLDAASEADLTAYSAARSADKSTSANRRLSVFRRYYAWAVREHRASADPTLRIRS
HHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
AKQPPRFPSTLTEAQVEALLGAPDVTTPLGLRDRTMLELMYASGLRVSELVTLKTVEVGL
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCC
NEGVVRVMGKGSKERLIPFGEEAHAWIERYLRESRPALLGQRSADALFVTARAEGMTRQQ
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCCCHHH
FWNIIKRHALTAHVHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHTDISTTQIYTHVA
HHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH
RERLKSLHAAHHPRG
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDVLTEDAQPASPAVSPLLLTSGASIDAFCDALWLEHGLARNTLDAYRRDLRLFSEWLA
CCCCCCCCCCCCCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERRDASLDAASEADLTAYSAARSADKSTSANRRLSVFRRYYAWAVREHRASADPTLRIRS
HHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
AKQPPRFPSTLTEAQVEALLGAPDVTTPLGLRDRTMLELMYASGLRVSELVTLKTVEVGL
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCC
NEGVVRVMGKGSKERLIPFGEEAHAWIERYLRESRPALLGQRSADALFVTARAEGMTRQQ
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCCCHHH
FWNIIKRHALTAHVHAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHTDISTTQIYTHVA
HHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH
RERLKSLHAAHHPRG
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]