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The map label for this gene is rcsB [H]

Identifier: 186475124

GI number: 186475124

Start: 400234

End: 400944

Strand: Direct

Name: rcsB [H]

Synonym: Bphy_0355

Alternate gene names: 186475124

Gene position: 400234-400944 (Clockwise)

Preceding gene: 186475123

Following gene: 186475125

Centisome position: 11.5

GC content: 60.2

Gene sequence:

>711_bases
GTGAATATCAGGAAGGACGGGACACTGCCAATTCGCACCATCATCGCCGACGACCACCCGCTCGTCTTGCTGGCGATGGA
GAATCTGATGTCGGGCTTTCCCAACATTGAAATCGTCGGCAAGGCAACGGATTCATCTGAGCTGTTCGCTGAGGCGCAGC
GTGTCAAATGCGAACTCGTCGTGATGGATCTATACATGCCCGGCGGTTTGCATGGCGACGGTGTCGAGATGGTACGGCAG
TTCAAGGAACGCCACCCTGACGTCGTCGTCGTGGTGCTGACCATGGAGACTTCGGCCGATGCGTTGCAAAAGGTGATTGC
GCTCGGCGTGGGCGCCGTCGTGAGCAAACGTGACCGAATCGACCTCATTCACGTGGCGATCATCACTGCGCTGGCGCGCG
AATGCTATGTCGGCCCCGCCATTCGCGCATTGCTCGCCGACGCCACCCTCTCGCGCCGGATCGACTATGTCAGACAGGTC
CTGTCGCGGCGCGAACTCGAAGTGCTGACGCACTATGCGACAGGGCGCGGTGTGACCGAAATAGCAATGAGGCTCGGCCG
CAGCGTCAAGACGATCAGCGCGCAGAAGTGCACTGCGATGCGCAAGTTGTCCCTGCAAAGCGATGCCGATCTGTTCCGGT
TCGCCGTCGAACATGGTCTGGTAACTGACGAGCAATCCACAGCGGCAGGCAGGACAGGCGGGCGAGGCTGA

Upstream 100 bases:

>100_bases
GGAACCATCTGATGTCTGCGGGAGGGTGGATGTCTGATTCTCGCCGGCTAACGGATCGCCGGATTTATACCAAGTTGCAG
GGTACAGGGAGAGACCACGC

Downstream 100 bases:

>100_bases
CGCGGCGGCACTCCGGACATAGAGAATTGACCGTTGTCGAGGGGACATTGTGCGATGACGGTTCAAGAACAAGAACAGAA
CAAGATGGAAGACAAGATTC

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MNIRKDGTLPIRTIIADDHPLVLLAMENLMSGFPNIEIVGKATDSSELFAEAQRVKCELVVMDLYMPGGLHGDGVEMVRQ
FKERHPDVVVVVLTMETSADALQKVIALGVGAVVSKRDRIDLIHVAIITALARECYVGPAIRALLADATLSRRIDYVRQV
LSRRELEVLTHYATGRGVTEIAMRLGRSVKTISAQKCTAMRKLSLQSDADLFRFAVEHGLVTDEQSTAAGRTGGRG

Sequences:

>Translated_236_residues
MNIRKDGTLPIRTIIADDHPLVLLAMENLMSGFPNIEIVGKATDSSELFAEAQRVKCELVVMDLYMPGGLHGDGVEMVRQ
FKERHPDVVVVVLTMETSADALQKVIALGVGAVVSKRDRIDLIHVAIITALARECYVGPAIRALLADATLSRRIDYVRQV
LSRRELEVLTHYATGRGVTEIAMRLGRSVKTISAQKCTAMRKLSLQSDADLFRFAVEHGLVTDEQSTAAGRTGGRG
>Mature_236_residues
MNIRKDGTLPIRTIIADDHPLVLLAMENLMSGFPNIEIVGKATDSSELFAEAQRVKCELVVMDLYMPGGLHGDGVEMVRQ
FKERHPDVVVVVLTMETSADALQKVIALGVGAVVSKRDRIDLIHVAIITALARECYVGPAIRALLADATLSRRIDYVRQV
LSRRELEVLTHYATGRGVTEIAMRLGRSVKTISAQKCTAMRKLSLQSDADLFRFAVEHGLVTDEQSTAAGRTGGRG

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=31.8627450980392, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788222, Length=215, Percent_Identity=26.046511627907, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=25.7281553398058, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786747, Length=227, Percent_Identity=27.3127753303965, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25808; Mature: 25808

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRKDGTLPIRTIIADDHPLVLLAMENLMSGFPNIEIVGKATDSSELFAEAQRVKCELV
CCCCCCCCCEEEEEEECCCCEEEEEHHHHHCCCCCEEEEEECCCHHHHHHHHHHCEEEEE
VMDLYMPGGLHGDGVEMVRQFKERHPDVVVVVLTMETSADALQKVIALGVGAVVSKRDRI
EEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCH
DLIHVAIITALARECYVGPAIRALLADATLSRRIDYVRQVLSRRELEVLTHYATGRGVTE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IAMRLGRSVKTISAQKCTAMRKLSLQSDADLFRFAVEHGLVTDEQSTAAGRTGGRG
HHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIRKDGTLPIRTIIADDHPLVLLAMENLMSGFPNIEIVGKATDSSELFAEAQRVKCELV
CCCCCCCCCEEEEEEECCCCEEEEEHHHHHCCCCCEEEEEECCCHHHHHHHHHHCEEEEE
VMDLYMPGGLHGDGVEMVRQFKERHPDVVVVVLTMETSADALQKVIALGVGAVVSKRDRI
EEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCH
DLIHVAIITALARECYVGPAIRALLADATLSRRIDYVRQVLSRRELEVLTHYATGRGVTE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IAMRLGRSVKTISAQKCTAMRKLSLQSDADLFRFAVEHGLVTDEQSTAAGRTGGRG
HHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]