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The map label for this gene is rcsB [H]

Identifier: 186475125

GI number: 186475125

Start: 400999

End: 401670

Strand: Direct

Name: rcsB [H]

Synonym: Bphy_0356

Alternate gene names: 186475125

Gene position: 400999-401670 (Clockwise)

Preceding gene: 186475124

Following gene: 186475126

Centisome position: 11.53

GC content: 61.01

Gene sequence:

>672_bases
ATGACGGTTCAAGAACAAGAACAGAACAAGATGGAAGACAAGATTCGCGTCATCGTCGCCGACGATCACGCATGCGTGCG
CGCGGGCGTCAGGTCATTGCTGGGGCAGATTGGCCATGTCGCGGTGGCCGGCGAAGCGGACAGCACGCAGGCTCTCGCCG
AATTGCTCGACTCCTGCGCGTGCGACGTCGTCGTGACGGATCTCGGCATGCCGGGCATCGACGGAGAGAGCAATGCCATT
CAGTTCCTGCGACGTCTGTTGGACCAGGCGCCGCATTTGCCCGTCGTCGTGCTCACGATGATCCATCAACCGTCCATCCT
GATGGGGTTGCTGCAGCATGGCGTTGCCGCGATCGTCGACAAGCGCGACATGACCGCGTCGTTGATACACGCGATCGACG
CTGGCCTGACGGGTCAAGGCTATCTGTCCGATCACGCATGCGCCGCAATCGCAAAGGCGGAAGCGCCGCAACCTCGCGCA
GGCGTAATGAGCGCCGGCGAATGGAAAGTCTTCACGATGTACGTGAGTGGGATGACGATCAGCCAGATTGCTGTCCGGCT
CAACCGCAGCGCCAAGACGATCAGCACGCAGAAGCGCAACGCAATGCGCAAGCTTGGACTGGAAACGGAAGCCGACGTGA
TCGACTACGCGTGCCAGATCGGCCTCACCTGA

Upstream 100 bases:

>100_bases
TGACGAGCAATCCACAGCGGCAGGCAGGACAGGCGGGCGAGGCTGACGCGGCGGCACTCCGGACATAGAGAATTGACCGT
TGTCGAGGGGACATTGTGCG

Downstream 100 bases:

>100_bases
TTGCATTTTCGGAGTTATCTGATTCGCAGCACTGTTCGCGGGATCAATAATTGTAGGTTGAACTCCCGGATTGCGAGTGT
GGCGCCACGTCATTGATTCG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTVQEQEQNKMEDKIRVIVADDHACVRAGVRSLLGQIGHVAVAGEADSTQALAELLDSCACDVVVTDLGMPGIDGESNAI
QFLRRLLDQAPHLPVVVLTMIHQPSILMGLLQHGVAAIVDKRDMTASLIHAIDAGLTGQGYLSDHACAAIAKAEAPQPRA
GVMSAGEWKVFTMYVSGMTISQIAVRLNRSAKTISTQKRNAMRKLGLETEADVIDYACQIGLT

Sequences:

>Translated_223_residues
MTVQEQEQNKMEDKIRVIVADDHACVRAGVRSLLGQIGHVAVAGEADSTQALAELLDSCACDVVVTDLGMPGIDGESNAI
QFLRRLLDQAPHLPVVVLTMIHQPSILMGLLQHGVAAIVDKRDMTASLIHAIDAGLTGQGYLSDHACAAIAKAEAPQPRA
GVMSAGEWKVFTMYVSGMTISQIAVRLNRSAKTISTQKRNAMRKLGLETEADVIDYACQIGLT
>Mature_222_residues
TVQEQEQNKMEDKIRVIVADDHACVRAGVRSLLGQIGHVAVAGEADSTQALAELLDSCACDVVVTDLGMPGIDGESNAIQ
FLRRLLDQAPHLPVVVLTMIHQPSILMGLLQHGVAAIVDKRDMTASLIHAIDAGLTGQGYLSDHACAAIAKAEAPQPRAG
VMSAGEWKVFTMYVSGMTISQIAVRLNRSAKTISTQKRNAMRKLGLETEADVIDYACQIGLT

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=33.6492890995261, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=26.7605633802817, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786747, Length=203, Percent_Identity=26.1083743842365, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=27.5, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23829; Mature: 23698

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQEQEQNKMEDKIRVIVADDHACVRAGVRSLLGQIGHVAVAGEADSTQALAELLDSCA
CCCCHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
CDVVVTDLGMPGIDGESNAIQFLRRLLDQAPHLPVVVLTMIHQPSILMGLLQHGVAAIVD
HHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHC
KRDMTASLIHAIDAGLTGQGYLSDHACAAIAKAEAPQPRAGVMSAGEWKVFTMYVSGMTI
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCHH
SQIAVRLNRSAKTISTQKRNAMRKLGLETEADVIDYACQIGLT
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVQEQEQNKMEDKIRVIVADDHACVRAGVRSLLGQIGHVAVAGEADSTQALAELLDSCA
CCCHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHH
CDVVVTDLGMPGIDGESNAIQFLRRLLDQAPHLPVVVLTMIHQPSILMGLLQHGVAAIVD
HHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHC
KRDMTASLIHAIDAGLTGQGYLSDHACAAIAKAEAPQPRAGVMSAGEWKVFTMYVSGMTI
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCHH
SQIAVRLNRSAKTISTQKRNAMRKLGLETEADVIDYACQIGLT
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]