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The map label for this gene is rcsB [H]

Identifier: 186475123

GI number: 186475123

Start: 399472

End: 400125

Strand: Direct

Name: rcsB [H]

Synonym: Bphy_0354

Alternate gene names: 186475123

Gene position: 399472-400125 (Clockwise)

Preceding gene: 186475122

Following gene: 186475124

Centisome position: 11.48

GC content: 61.31

Gene sequence:

>654_bases
ATGCTTGCAGACGATCACCCGTTTGTCCTGCTCGGTATCCGGGCCACGCTGATCGCGCACGGCGGATTCACAATCGTAGG
CGAGGCGACGAGCCCTTCGTCGCTCGTTCAGTTAATGGAAAAGGCGTCATGCGACGTACTGGTCACGGATCTGACCATGC
CGGATGCATCGGGCGACGCCGACGACGGGCTGCGGCTGATCCGGCGCATTCGAAGCGGCTGGCCGGAGGTCCACATCGTC
GTGCTGACCAGTCTGACCAACGCGGCCATTCTCCGCTCCATCATGTCCGACGGCGTGATCGGCATGCTCAACAAGAGTGA
ATCGATGGATGAACTGGCCGCTGCAATACGCGCGGCGGGTGCAGGACGTTCCTACGTCAGCCGGTCGATACTTCAGACAC
TCGCTGAGGCGAGCGGCGAGCCGCTCGGCATGTCGCCAATGCGCCATCTTTCCCCGCGCCAGTCAGAGGTGATCCGCATG
TTCGTGCGGGGCAAGTCCATATCCGAAATCGCCCGCGATCTGGGGCGGGACGTCCGGACGGTTAGCCGGCAAAAGCGCGA
CGCAATGGCGAAACTGGGCGTCAGCAATGACCCCGGGCTTTTTGCTTTCGTGCGCGCATATGGTCTTGCATCGGAATTCA
TTTTGGATCGCTAA

Upstream 100 bases:

>100_bases
CTGTATTAAAGCGGGCTCGTTTTGACGTTGTGTCGAAATGGGCGTTTCGGCGTCGACAACACAAACCAATAACCAGGCGG
CAACTGTGAATCTTCGAATC

Downstream 100 bases:

>100_bases
TCAAATTCGGAACCATCTGATGTCTGCGGGAGGGTGGATGTCTGATTCTCGCCGGCTAACGGATCGCCGGATTTATACCA
AGTTGCAGGGTACAGGGAGA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MLADDHPFVLLGIRATLIAHGGFTIVGEATSPSSLVQLMEKASCDVLVTDLTMPDASGDADDGLRLIRRIRSGWPEVHIV
VLTSLTNAAILRSIMSDGVIGMLNKSESMDELAAAIRAAGAGRSYVSRSILQTLAEASGEPLGMSPMRHLSPRQSEVIRM
FVRGKSISEIARDLGRDVRTVSRQKRDAMAKLGVSNDPGLFAFVRAYGLASEFILDR

Sequences:

>Translated_217_residues
MLADDHPFVLLGIRATLIAHGGFTIVGEATSPSSLVQLMEKASCDVLVTDLTMPDASGDADDGLRLIRRIRSGWPEVHIV
VLTSLTNAAILRSIMSDGVIGMLNKSESMDELAAAIRAAGAGRSYVSRSILQTLAEASGEPLGMSPMRHLSPRQSEVIRM
FVRGKSISEIARDLGRDVRTVSRQKRDAMAKLGVSNDPGLFAFVRAYGLASEFILDR
>Mature_217_residues
MLADDHPFVLLGIRATLIAHGGFTIVGEATSPSSLVQLMEKASCDVLVTDLTMPDASGDADDGLRLIRRIRSGWPEVHIV
VLTSLTNAAILRSIMSDGVIGMLNKSESMDELAAAIRAAGAGRSYVSRSILQTLAEASGEPLGMSPMRHLSPRQSEVIRM
FVRGKSISEIARDLGRDVRTVSRQKRDAMAKLGVSNDPGLFAFVRAYGLASEFILDR

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=211, Percent_Identity=36.4928909952607, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=29.7169811320755, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788712, Length=205, Percent_Identity=24.8780487804878, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788521, Length=194, Percent_Identity=28.3505154639175, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23365; Mature: 23365

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLADDHPFVLLGIRATLIAHGGFTIVGEATSPSSLVQLMEKASCDVLVTDLTMPDASGDA
CCCCCCCEEEEEHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCH
DDGLRLIRRIRSGWPEVHIVVLTSLTNAAILRSIMSDGVIGMLNKSESMDELAAAIRAAG
HHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
AGRSYVSRSILQTLAEASGEPLGMSPMRHLSPRQSEVIRMFVRGKSISEIARDLGRDVRT
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VSRQKRDAMAKLGVSNDPGLFAFVRAYGLASEFILDR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLADDHPFVLLGIRATLIAHGGFTIVGEATSPSSLVQLMEKASCDVLVTDLTMPDASGDA
CCCCCCCEEEEEHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCH
DDGLRLIRRIRSGWPEVHIVVLTSLTNAAILRSIMSDGVIGMLNKSESMDELAAAIRAAG
HHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHCC
AGRSYVSRSILQTLAEASGEPLGMSPMRHLSPRQSEVIRMFVRGKSISEIARDLGRDVRT
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VSRQKRDAMAKLGVSNDPGLFAFVRAYGLASEFILDR
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]