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The map label for this gene is ssb [H]

Identifier: 186475110

GI number: 186475110

Start: 385525

End: 386043

Strand: Direct

Name: ssb [H]

Synonym: Bphy_0341

Alternate gene names: 186475110

Gene position: 385525-386043 (Clockwise)

Preceding gene: 186475109

Following gene: 186475112

Centisome position: 11.08

GC content: 64.35

Gene sequence:

>519_bases
ATGGCATCCGTGAACAAGGTCATTCTCGTCGGCAATCTGGGCGCCGATCCGGAAGTTCGTTATCTTCCGAGCGGCGACGC
GGTGGCGAACATTCGCCTTGCCACGACCGATCGCTACAAGGACAAGCAGTCGGGCGAATTCAAGGAAATGACGGAATGGC
ACCGCATTTCGTTCTTCGGGCGCCTCGCTGAAATCGTGTCCGAATACCTGAAGAAGGGCTCGTCGGTGTATATCGAAGGC
CGCATCCGTACGCGCAAGTACCAGGCACAGGACGGCACCGACCGTTATTCGACGGAAATCGTCGCTGACCAGATGCAGAT
GCTCGGCGGCCGTAGCGGTGGCGGTGGTGGTGGCGACGACGGCGGCTACAGCCGCGGCGAACCGATGGAGCGCGGCGGTG
GCCGTATGTCGGGCGGCGGCGGTGGCCGTGTCGCGGGCGGCGGTGGCGGCGGTCAGAGCCGTCCGAGCGCGCCGGCCGGC
GGCGGCTTCGACGAGATGGACGACGATATTCCGTTCTAG

Upstream 100 bases:

>100_bases
GGCGGGTAACGGGGCGCGCTTTCCGGTCACTCTGAGGCGGCCGTGGCGTAGACAGCCATCCAGTGCCGCGTCGCCGGAAC
GGAATCAACAGGAGAAACTC

Downstream 100 bases:

>100_bases
CCGTTCGAGGCTGCACACGCGCATCGAGCATCGTGCGTCGAACGAATGCAAGAAAAAACACCCCGCCCATCGAGCGGGGT
GTTTTTTTAAGGGCAGGCGA

Product: single-stranded DNA-binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MASVNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDKQSGEFKEMTEWHRISFFGRLAEIVSEYLKKGSSVYIEG
RIRTRKYQAQDGTDRYSTEIVADQMQMLGGRSGGGGGGDDGGYSRGEPMERGGGRMSGGGGGRVAGGGGGGQSRPSAPAG
GGFDEMDDDIPF

Sequences:

>Translated_172_residues
MASVNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDKQSGEFKEMTEWHRISFFGRLAEIVSEYLKKGSSVYIEG
RIRTRKYQAQDGTDRYSTEIVADQMQMLGGRSGGGGGGDDGGYSRGEPMERGGGRMSGGGGGRVAGGGGGGQSRPSAPAG
GGFDEMDDDIPF
>Mature_171_residues
ASVNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDKQSGEFKEMTEWHRISFFGRLAEIVSEYLKKGSSVYIEGR
IRTRKYQAQDGTDRYSTEIVADQMQMLGGRSGGGGGGDDGGYSRGEPMERGGGRMSGGGGGRVAGGGGGGQSRPSAPAGG
GFDEMDDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=116, Percent_Identity=33.6206896551724, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1790494, Length=182, Percent_Identity=53.8461538461538, Blast_Score=172, Evalue=1e-44,
Organism=Drosophila melanogaster, GI85725234, Length=102, Percent_Identity=36.2745098039216, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24647376, Length=102, Percent_Identity=36.2745098039216, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 18152; Mature: 18021

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDKQSGEFKEMTEWHRISFFG
CCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RLAEIVSEYLKKGSSVYIEGRIRTRKYQAQDGTDRYSTEIVADQMQMLGGRSGGGGGGDD
HHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
GGYSRGEPMERGGGRMSGGGGGRVAGGGGGGQSRPSAPAGGGFDEMDDDIPF
CCCCCCCCHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASVNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDKQSGEFKEMTEWHRISFFG
CCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RLAEIVSEYLKKGSSVYIEGRIRTRKYQAQDGTDRYSTEIVADQMQMLGGRSGGGGGGDD
HHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
GGYSRGEPMERGGGRMSGGGGGRVAGGGGGGQSRPSAPAGGGFDEMDDDIPF
CCCCCCCCHHHCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948488 [H]