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The map label for this gene is yjcC [H]

Identifier: 186474910

GI number: 186474910

Start: 155217

End: 156491

Strand: Direct

Name: yjcC [H]

Synonym: Bphy_0140

Alternate gene names: 186474910

Gene position: 155217-156491 (Clockwise)

Preceding gene: 186474908

Following gene: 186474911

Centisome position: 4.46

GC content: 63.53

Gene sequence:

>1275_bases
ATGACCATTGCGCAACAGGAAAAAACCACGGTGCCGCACGGCTTCGAGCTCAGCATGACCTCGGGCCTGCAGCGCTATTC
GGTGCAACACGGCGAGCTGACGCTCACGAGCGTCTTCCAGCCGATATTCAGTCTGTCGCACATGCGTGCCGTGGGCTATG
AAGGCTTGTTGCGCGCGCATGACCCGTTCGACCGTGCCGTGTCGCCCGTCGATGTGTTCGGCCACGCGGCGCGCGTCGGC
GATGTGCTGCATGTCGACCGGCTCGCGCAGTCGCTGCATCTCGAGAACTTCAAGGTGCTCGGCGCGGAGCGCGAGTGGCT
GTTTCTGAACGTCCATCCGGGCGTGCTGATCGACTCGTATCATTCGGCTGCACTGCTCGCAAATTTGCGTCGTTTGAACC
TGTCGCCGCGCCGCATCGTGCTCGAAGTGCTCGAACAGAGCGCGGAAGATATCGAACGTCTTGCCGACGCCGTGCGCCAG
TTCCGCGAGCGCGGCTTTCTGATCGCGCTCGATGACTTCGGCGCGGGGCATTCGAATATCGAACGCATCTGGCAGCTCAA
TCCCGACATCGTCAAGCTCGATCGCATCATGCTGTCGCACGCGGCGCATCGTGCGGATGTCGCGTCGATTCTGCCCGGGC
TCGTCGCATTGCTGCACGAGGCGGGCAAGCTGGTGCTGATCGAAGGCGTCGAGACGGAGCACGAAGCGCACATGGCAATG
GAGTGCAATGTCGATTTCGTGCAGGGTTTTTTCTTTGGGCGTCCGCATCCTGGTCTCGCGGACGCCGCGCACGCGGCCGC
CTGCATCGGCGAGCTGACCGAGCGTTATCAGACGCAAACGGAACAGCGCGAGCGACGCAACGCGTCGCGGCTCGCGCCAT
ACATTCGCGCATTCGAGCGCGCGGCGGAACGGCTTGCCGCGGGTGAACTGCTCGATGAAGTGTGCTGGAATTTTCTCGCG
CTCGATCACGCGGCGCGCTGCTATCTGCTCGACGACAAGGGCCGTCAGGCGGGACGCAACGTGGTGTTGCGCGCGGACCG
CGCGTCGCACGAAACGCGCTTCCTGCCGCTATCCGATGCGCAGGGCGCGAACTGGCTGCGCCGGCCGTATTTCCGCGCGG
CAATCGAGGCACCTGAACGCGTGCATGTGACGCGGCCTTATCTGTCGATTAACGAAGCGGTGCCCTGCGTCACGTTGTCG
GTGGCGACGCAGATCGGCAGTCGCATGTGCGTGCTGTGCGGCGATATCGACTGGTTCGAGGAGCCGCACTTCTGA

Upstream 100 bases:

>100_bases
TGGAGCTTGCTTAAGGGGGCAACAACGCACATTCCGAGAACGGCCGCGGCTCTTTCGCATTCGCGACGCGCGCGCCGTGA
CTCCTGCGTCAGAGGATTGC

Downstream 100 bases:

>100_bases
CATCATGTCTGTCTTGTTCTTCTTGACGACGTGACTTCCTTGACATGCGAAACGAACGGGTATTGCTCGAAGTCATCGCG
ACGACGGTTGCCGATGCGAA

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTIAQQEKTTVPHGFELSMTSGLQRYSVQHGELTLTSVFQPIFSLSHMRAVGYEGLLRAHDPFDRAVSPVDVFGHAARVG
DVLHVDRLAQSLHLENFKVLGAEREWLFLNVHPGVLIDSYHSAALLANLRRLNLSPRRIVLEVLEQSAEDIERLADAVRQ
FRERGFLIALDDFGAGHSNIERIWQLNPDIVKLDRIMLSHAAHRADVASILPGLVALLHEAGKLVLIEGVETEHEAHMAM
ECNVDFVQGFFFGRPHPGLADAAHAAACIGELTERYQTQTEQRERRNASRLAPYIRAFERAAERLAAGELLDEVCWNFLA
LDHAARCYLLDDKGRQAGRNVVLRADRASHETRFLPLSDAQGANWLRRPYFRAAIEAPERVHVTRPYLSINEAVPCVTLS
VATQIGSRMCVLCGDIDWFEEPHF

Sequences:

>Translated_424_residues
MTIAQQEKTTVPHGFELSMTSGLQRYSVQHGELTLTSVFQPIFSLSHMRAVGYEGLLRAHDPFDRAVSPVDVFGHAARVG
DVLHVDRLAQSLHLENFKVLGAEREWLFLNVHPGVLIDSYHSAALLANLRRLNLSPRRIVLEVLEQSAEDIERLADAVRQ
FRERGFLIALDDFGAGHSNIERIWQLNPDIVKLDRIMLSHAAHRADVASILPGLVALLHEAGKLVLIEGVETEHEAHMAM
ECNVDFVQGFFFGRPHPGLADAAHAAACIGELTERYQTQTEQRERRNASRLAPYIRAFERAAERLAAGELLDEVCWNFLA
LDHAARCYLLDDKGRQAGRNVVLRADRASHETRFLPLSDAQGANWLRRPYFRAAIEAPERVHVTRPYLSINEAVPCVTLS
VATQIGSRMCVLCGDIDWFEEPHF
>Mature_423_residues
TIAQQEKTTVPHGFELSMTSGLQRYSVQHGELTLTSVFQPIFSLSHMRAVGYEGLLRAHDPFDRAVSPVDVFGHAARVGD
VLHVDRLAQSLHLENFKVLGAEREWLFLNVHPGVLIDSYHSAALLANLRRLNLSPRRIVLEVLEQSAEDIERLADAVRQF
RERGFLIALDDFGAGHSNIERIWQLNPDIVKLDRIMLSHAAHRADVASILPGLVALLHEAGKLVLIEGVETEHEAHMAME
CNVDFVQGFFFGRPHPGLADAAHAAACIGELTERYQTQTEQRERRNASRLAPYIRAFERAAERLAAGELLDEVCWNFLAL
DHAARCYLLDDKGRQAGRNVVLRADRASHETRFLPLSDAQGANWLRRPYFRAAIEAPERVHVTRPYLSINEAVPCVTLSV
ATQIGSRMCVLCGDIDWFEEPHF

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=249, Percent_Identity=26.5060240963855, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082096, Length=154, Percent_Identity=30.5194805194805, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788502, Length=228, Percent_Identity=28.0701754385965, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787055, Length=243, Percent_Identity=24.2798353909465, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081743, Length=231, Percent_Identity=25.1082251082251, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787541, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=26.4705882352941, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788849, Length=248, Percent_Identity=24.5967741935484, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081921, Length=252, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786507, Length=223, Percent_Identity=24.6636771300448, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081980, Length=225, Percent_Identity=24.8888888888889, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI226510982, Length=235, Percent_Identity=26.3829787234043, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 47634; Mature: 47503

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAQQEKTTVPHGFELSMTSGLQRYSVQHGELTLTSVFQPIFSLSHMRAVGYEGLLRAH
CCCCCCCCCCCCCCEEEHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCC
DPFDRAVSPVDVFGHAARVGDVLHVDRLAQSLHLENFKVLGAEREWLFLNVHPGVLIDSY
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEECH
HSAALLANLRRLNLSPRRIVLEVLEQSAEDIERLADAVRQFRERGFLIALDDFGAGHSNI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
ERIWQLNPDIVKLDRIMLSHAAHRADVASILPGLVALLHEAGKLVLIEGVETEHEAHMAM
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEE
ECNVDFVQGFFFGRPHPGLADAAHAAACIGELTERYQTQTEQRERRNASRLAPYIRAFER
ECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
AAERLAAGELLDEVCWNFLALDHAARCYLLDDKGRQAGRNVVLRADRASHETRFLPLSDA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCEEEEECCCC
QGANWLRRPYFRAAIEAPERVHVTRPYLSINEAVPCVTLSVATQIGSRMCVLCGDIDWFE
CCCCHHHHHHHHHHHCCCCEEEEECCCEECCCCCCEEHHHHHHHHCCCEEEEECCCCCCC
EPHF
CCCC
>Mature Secondary Structure 
TIAQQEKTTVPHGFELSMTSGLQRYSVQHGELTLTSVFQPIFSLSHMRAVGYEGLLRAH
CCCCCCCCCCCCCEEEHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCC
DPFDRAVSPVDVFGHAARVGDVLHVDRLAQSLHLENFKVLGAEREWLFLNVHPGVLIDSY
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEECH
HSAALLANLRRLNLSPRRIVLEVLEQSAEDIERLADAVRQFRERGFLIALDDFGAGHSNI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHH
ERIWQLNPDIVKLDRIMLSHAAHRADVASILPGLVALLHEAGKLVLIEGVETEHEAHMAM
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEE
ECNVDFVQGFFFGRPHPGLADAAHAAACIGELTERYQTQTEQRERRNASRLAPYIRAFER
ECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
AAERLAAGELLDEVCWNFLALDHAARCYLLDDKGRQAGRNVVLRADRASHETRFLPLSDA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCEEEEECCCC
QGANWLRRPYFRAAIEAPERVHVTRPYLSINEAVPCVTLSVATQIGSRMCVLCGDIDWFE
CCCCHHHHHHHHHHHCCCCEEEEECCCEECCCCCCEEHHHHHHHHCCCEEEEECCCCCCC
EPHF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]