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The map label for this gene is rutG [H]

Identifier: 186474908

GI number: 186474908

Start: 151789

End: 153096

Strand: Direct

Name: rutG [H]

Synonym: Bphy_0138

Alternate gene names: 186474908

Gene position: 151789-153096 (Clockwise)

Preceding gene: 186474907

Following gene: 186474910

Centisome position: 4.36

GC content: 64.98

Gene sequence:

>1308_bases
ATGGCGGATTCCTATTTCCCGCGCTGGCGCGTCCAGCCAAAAAGCGTCGAAGGGCGCGTCGTCAATATCGACGAGCGCCT
GCCCTGGCCGCAAATGTTCGCAATGGGCGTCCAGCACGTCGTCGCGATGTTCGGCTCGACGGTGCTCGCGCCCCTGTTGA
TGGGCTTCGATCCCAATCTGTGCATCTTCATGTCGGGCATTGGCACGCTGCTGTTCTTCGTGCTGGTCGGCGGCCGCGTG
CCGAGCTATCTCGGGTCGAGCTTCGCGTTCATCGGGCTCGTGATCGCGATCACCGGTTACACGGGGCACGGACCAAACAT
GAATATACCCGTCGCGCTCGGCGGGATCATCGCGTGCGGCGTCGCTTACGTCGTCATTGGGCTGATCGTGTCGGCGATCG
GCACCGCATGGATCGAAACGCTGATGCCACCCGTCGTGACGGGCTCGATCGTCGCGGTGATCGGCCTGAATCTCGCGCCG
ATCGCCGTCAAGGGTGTGAGCGGCAGCGCGTTCGATTCGTACATGGCGCTGGTCACAGTGCTGTGCGTCGGCGCTGTCGC
CGTGTTCGCGCACGGCATGCTGCAGCGCCTGCTGATACTCGTCGGCCTGCTGATCGCGTACGCGATCTACGCCGTCGTGA
CGAATGGCATGGGCATGGGCAAGCCGATCGATTTTTCGATCGTTGCGAACGCGCCGTGGTTCGGCATGCCGCATTTCATG
GCGCCCGTCTTCAGCGGCCAGGCGATGGCGCTGCTGGCGCCCGTCGCGGTGATTCTCGTCGCGGAGAACCTCGGCCACAT
CAAGGCGGTGAGCGCGATGACGGGGCAGAACCTCGACGGCTACATCGGTCGCGCGTTCATCGGCGATGGACTGGCGACCG
TCCTCTCCGGCTTCGCAGGCGGCACGGGCGTGACGACCTACGCGGAAAACATCGGCGTGATGGCCGTCACGAAGATTTAC
TCGACGCTGGTGTTCGTGATTGCTGCGCTGATCGCGCTGGTGCTCGGCTTCTCGCCGAAGTTCGGCGCCGTGATCCAGAC
CATTCCGGGCCCGGTGCTGGGCGGCGTGTCGATCGTCGTGTTCGGGCTGATCGCGGTGACGGGCGCGCGCATCTGGGTCG
TCAACAAGGTCAACTTCTCGGACAACCGCAACCTGATCGTCGCGGCCGTGACGCTCGTGCTCGGCGCGGGCGACTTCTCG
CTGAAGTTCGGCGGCTTCGCGCTCGGCGGCATCGGCACGGCGACGTTCGGCGCGATCATCCTGTACGCGCTGCTGCGTCG
TAAAGGCCCGCAGGAGCCGGCCGTCTGA

Upstream 100 bases:

>100_bases
GCGCGTAGTTCAAGAGTCCCATCCTGGACGGCGCCGCCTTGCAACACACTGACGCGGCACTTCCATACAAGATCTACGCC
AATAGAGGAGAACCCCCGCG

Downstream 100 bases:

>100_bases
TCAGCCGCATGCACGAAACGAAACGGGCGCCCATCGCGGCGCCCGTTTTTTTGCTTCTACTTCTTCCCGCTTTATTTCTT
TCCCTTACCGCGTGTCTGCA

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MADSYFPRWRVQPKSVEGRVVNIDERLPWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAITGYTGHGPNMNIPVALGGIIACGVAYVVIGLIVSAIGTAWIETLMPPVVTGSIVAVIGLNLAP
IAVKGVSGSAFDSYMALVTVLCVGAVAVFAHGMLQRLLILVGLLIAYAIYAVVTNGMGMGKPIDFSIVANAPWFGMPHFM
APVFSGQAMALLAPVAVILVAENLGHIKAVSAMTGQNLDGYIGRAFIGDGLATVLSGFAGGTGVTTYAENIGVMAVTKIY
STLVFVIAALIALVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVNFSDNRNLIVAAVTLVLGAGDFS
LKFGGFALGGIGTATFGAIILYALLRRKGPQEPAV

Sequences:

>Translated_435_residues
MADSYFPRWRVQPKSVEGRVVNIDERLPWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRV
PSYLGSSFAFIGLVIAITGYTGHGPNMNIPVALGGIIACGVAYVVIGLIVSAIGTAWIETLMPPVVTGSIVAVIGLNLAP
IAVKGVSGSAFDSYMALVTVLCVGAVAVFAHGMLQRLLILVGLLIAYAIYAVVTNGMGMGKPIDFSIVANAPWFGMPHFM
APVFSGQAMALLAPVAVILVAENLGHIKAVSAMTGQNLDGYIGRAFIGDGLATVLSGFAGGTGVTTYAENIGVMAVTKIY
STLVFVIAALIALVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVNFSDNRNLIVAAVTLVLGAGDFS
LKFGGFALGGIGTATFGAIILYALLRRKGPQEPAV
>Mature_434_residues
ADSYFPRWRVQPKSVEGRVVNIDERLPWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNLCIFMSGIGTLLFFVLVGGRVP
SYLGSSFAFIGLVIAITGYTGHGPNMNIPVALGGIIACGVAYVVIGLIVSAIGTAWIETLMPPVVTGSIVAVIGLNLAPI
AVKGVSGSAFDSYMALVTVLCVGAVAVFAHGMLQRLLILVGLLIAYAIYAVVTNGMGMGKPIDFSIVANAPWFGMPHFMA
PVFSGQAMALLAPVAVILVAENLGHIKAVSAMTGQNLDGYIGRAFIGDGLATVLSGFAGGTGVTTYAENIGVMAVTKIYS
TLVFVIAALIALVLGFSPKFGAVIQTIPGPVLGGVSIVVFGLIAVTGARIWVVNKVNFSDNRNLIVAAVTLVLGAGDFSL
KFGGFALGGIGTATFGAIILYALLRRKGPQEPAV

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=444, Percent_Identity=24.5495495495495, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI44680143, Length=176, Percent_Identity=29.5454545454545, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI44680148, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI40316845, Length=171, Percent_Identity=29.8245614035088, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081818, Length=428, Percent_Identity=70.7943925233645, Blast_Score=593, Evalue=1e-171,
Organism=Escherichia coli, GI1788843, Length=429, Percent_Identity=36.8298368298368, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI87082181, Length=459, Percent_Identity=25.7080610021786, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082178, Length=407, Percent_Identity=26.044226044226, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790087, Length=414, Percent_Identity=24.3961352657005, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17541904, Length=209, Percent_Identity=29.1866028708134, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71993493, Length=214, Percent_Identity=29.4392523364486, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=181, Percent_Identity=30.3867403314917, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17542262, Length=176, Percent_Identity=28.4090909090909, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558856, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356175, Length=178, Percent_Identity=34.2696629213483, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44996; Mature: 44865

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCCCCCC
>Mature Secondary Structure 
ADSYFPRWRVQPKSVEGRVVNIDERLPWPQMFAMGVQHVVAMFGSTVLAPLLMGFDPNL
CCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
CIFMSGIGTLLFFVLVGGRVPSYLGSSFAFIGLVIAITGYTGHGPNMNIPVALGGIIACG
HHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
VAYVVIGLIVSAIGTAWIETLMPPVVTGSIVAVIGLNLAPIAVKGVSGSAFDSYMALVTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHH
LCVGAVAVFAHGMLQRLLILVGLLIAYAIYAVVTNGMGMGKPIDFSIVANAPWFGMPHFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHH
APVFSGQAMALLAPVAVILVAENLGHIKAVSAMTGQNLDGYIGRAFIGDGLATVLSGFAG
HHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHCCC
GTGVTTYAENIGVMAVTKIYSTLVFVIAALIALVLGFSPKFGAVIQTIPGPVLGGVSIVV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHH
FGLIAVTGARIWVVNKVNFSDNRNLIVAAVTLVLGAGDFSLKFGGFALGGIGTATFGAII
HHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEECCEEECCHHHHHHHHHH
LYALLRRKGPQEPAV
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]