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The map label for this gene is tcp [H]

Identifier: 186474907

GI number: 186474907

Start: 150067

End: 151614

Strand: Direct

Name: tcp [H]

Synonym: Bphy_0137

Alternate gene names: 186474907

Gene position: 150067-151614 (Clockwise)

Preceding gene: 186474906

Following gene: 186474908

Centisome position: 4.31

GC content: 67.05

Gene sequence:

>1548_bases
ATGATGAAGTGGTTTGACCGCATGTCCGTCTGGAAGAAACTGCTGATCGCGTTTGCCGCCGTGATCGGCTTCGGTGTCGC
CGTTGGTGCGGCAGGATTGTCGGCGCTGGCGTCGATGCACGGCATGACGGAGGAGATTTCGAGCCGGCACATGGACGGCC
TCTACTGGATGGAAGAGGCGAACCGCTACAAGATCGACACTGACCTCGATGCGGCGAATCTCGGCTACGCGCCGGACGAA
GCGGCGCGTAAGAAGCTCAAGGACGACATCGTCGCGTCGCTGAAAAACATGCACGACGCGTACGGCCTCTATCGCGCGAC
GATCGCCGGCGCCGACGGCCAGGCGCTCTACGACGACGTGCTGCGCAAGACCGACGCGTGGGAGGCGATCGTGCATCAGC
AGATCGGTTTGCAGCCGGTTCCCTCAGGCGTCGACGAACTGGTGCGGCGCGCGATCGCCGCGAGCGAGACGCTGCGCGAC
GCGATCGTCGTACTGATCGATTACCGGCGCAAGCAGGCGAACGCCGCGCAGCACGAAGCGGGCGCCGAATACGCGCGCAT
GCGGGTCGTGCTGTCGCTGCTGGTGCTGGCGTCGATGGCAGTCGGCGCGGCATTCGCGTGGCTGATCGCGCGGCGTCTGA
CCCGCCAGCTTGGCGGCGAGCCCGGCTACGCGATGCAGATCGCGAGGCGGATCGCGGCGGGCGATCTCACCGTGCGCGTC
GACACGAAACCCGGCGACACCGCGAGTCTGATGCACGCGCTGGCCAACATGCGCGCGCAACTGGCGGCGATCGTCGGCAA
GATCAACGAGTCGAGCGAATCGATCCTGCTTGCATCGGGTGAAATCGAACAGGGCAACACGGACCTGTCGCAGCGTACCG
AGGAGCAGGCCGCGTCGCTGGAAGAAACGGCGTCGAGCATGGAGCAACTGACGGCGACCGTCCGCCAGAACGCCGACAAC
GCGCAGCAGGCAGGGGGTGTCGCACGCGGCGCGTCGGAAGTGGCGCTGCGCGGCAGCGGCCTCGTGCGCGAAGTGGTCGA
CACGATGCGCGAACTCGCGTCCGGCTCGAAGCGGATGACGGACATCATCGGCGTAATCGAGAGCATTGCGTTCCAGACCA
ACATTCTCGCGCTCAACGCGGCCGTCGAAGCCGCGCGCGCGGGCGAGCAGGGGCGCGGTTTCGCCGTCGTCGCGGCCGAG
GTGCGTGCGCTCGCGCAGCGCAGCGCGGTATCGGCGAAGGAGATCAAGGAACTGATCGAAAGCTCGACCTCGCGCGTGGA
CAGCGGCGCGGTGCTCGCCGAGCGCGCGGGCCGCACGATGGCGGAAGTCACGCAGGCCGTGCGGCGGATGACGGACCTCA
TGGGTGAGATATCGGCGGCCTCGAGCGAGCAGAGCACGGGCATCGAACAGGTGAACCGGGCCGTCGCGCAGATGGACGAA
GTCACCCAACAAAACGCCGCGCTCGTCGAGCAGGCGGCGGCTGCGGCGGGCGCGATGGCCGGTCAGGCGCGTCATCTGAA
GACGGCCGTCGCGGTATTTTCGCTTTGA

Upstream 100 bases:

>100_bases
CCGGCATCCATTCATCAAGTCCGCATAACGGGCGCCGTAAAGCATTGCAGCTTGCCGGCCCATTGCCTGCCCATCCGGCT
GATGAACTGTCGAGGATCGC

Downstream 100 bases:

>100_bases
TACAACAGCGAGACAACGCGAACCCGCGCAGCAGTTTGCGCGGCTTGTCAGCGCCAGGCGCTCTCCGTACACTCGCGCGT
AGTTCAAGAGTCCCATCCTG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MMKWFDRMSVWKKLLIAFAAVIGFGVAVGAAGLSALASMHGMTEEISSRHMDGLYWMEEANRYKIDTDLDAANLGYAPDE
AARKKLKDDIVASLKNMHDAYGLYRATIAGADGQALYDDVLRKTDAWEAIVHQQIGLQPVPSGVDELVRRAIAASETLRD
AIVVLIDYRRKQANAAQHEAGAEYARMRVVLSLLVLASMAVGAAFAWLIARRLTRQLGGEPGYAMQIARRIAAGDLTVRV
DTKPGDTASLMHALANMRAQLAAIVGKINESSESILLASGEIEQGNTDLSQRTEEQAASLEETASSMEQLTATVRQNADN
AQQAGGVARGASEVALRGSGLVREVVDTMRELASGSKRMTDIIGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAE
VRALAQRSAVSAKEIKELIESSTSRVDSGAVLAERAGRTMAEVTQAVRRMTDLMGEISAASSEQSTGIEQVNRAVAQMDE
VTQQNAALVEQAAAAAGAMAGQARHLKTAVAVFSL

Sequences:

>Translated_515_residues
MMKWFDRMSVWKKLLIAFAAVIGFGVAVGAAGLSALASMHGMTEEISSRHMDGLYWMEEANRYKIDTDLDAANLGYAPDE
AARKKLKDDIVASLKNMHDAYGLYRATIAGADGQALYDDVLRKTDAWEAIVHQQIGLQPVPSGVDELVRRAIAASETLRD
AIVVLIDYRRKQANAAQHEAGAEYARMRVVLSLLVLASMAVGAAFAWLIARRLTRQLGGEPGYAMQIARRIAAGDLTVRV
DTKPGDTASLMHALANMRAQLAAIVGKINESSESILLASGEIEQGNTDLSQRTEEQAASLEETASSMEQLTATVRQNADN
AQQAGGVARGASEVALRGSGLVREVVDTMRELASGSKRMTDIIGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAE
VRALAQRSAVSAKEIKELIESSTSRVDSGAVLAERAGRTMAEVTQAVRRMTDLMGEISAASSEQSTGIEQVNRAVAQMDE
VTQQNAALVEQAAAAAGAMAGQARHLKTAVAVFSL
>Mature_515_residues
MMKWFDRMSVWKKLLIAFAAVIGFGVAVGAAGLSALASMHGMTEEISSRHMDGLYWMEEANRYKIDTDLDAANLGYAPDE
AARKKLKDDIVASLKNMHDAYGLYRATIAGADGQALYDDVLRKTDAWEAIVHQQIGLQPVPSGVDELVRRAIAASETLRD
AIVVLIDYRRKQANAAQHEAGAEYARMRVVLSLLVLASMAVGAAFAWLIARRLTRQLGGEPGYAMQIARRIAAGDLTVRV
DTKPGDTASLMHALANMRAQLAAIVGKINESSESILLASGEIEQGNTDLSQRTEEQAASLEETASSMEQLTATVRQNADN
AQQAGGVARGASEVALRGSGLVREVVDTMRELASGSKRMTDIIGVIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAE
VRALAQRSAVSAKEIKELIESSTSRVDSGAVLAERAGRTMAEVTQAVRRMTDLMGEISAASSEQSTGIEQVNRAVAQMDE
VTQQNAALVEQAAAAAGAMAGQARHLKTAVAVFSL

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=289, Percent_Identity=58.477508650519, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI2367378, Length=288, Percent_Identity=59.375, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788194, Length=332, Percent_Identity=49.6987951807229, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1787690, Length=416, Percent_Identity=43.9903846153846, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI1789453, Length=326, Percent_Identity=35.2760736196319, Blast_Score=181, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 54841; Mature: 54841

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]