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The map label for this gene is 183222458

Identifier: 183222458

GI number: 183222458

Start: 3227644

End: 3228048

Strand: Reverse

Name: 183222458

Synonym: LEPBI_I3112

Alternate gene names: NA

Gene position: 3228048-3227644 (Counterclockwise)

Preceding gene: 183222461

Following gene: 183222453

Centisome position: 89.68

GC content: 45.68

Gene sequence:

>405_bases
ATGTTTACCCAAGAAAACGGGAAATTTTATGTCCGTATTGAAGGCCGGTTTGAGTCCGCGCATTTCCTCTACCAGTACTT
TGCCGATGGGACCGACGAGCCCATCCACGGCCATTCCTGGAAGGTTGAGGTCTATCTGGAAGGAAAAACGAACATCCGAC
CAGATGGGATATCCTATGACTTTTTGACAGCAAGGAACAAACTTTTGGCTCTTGTCCATTCCATCGATCACATCCTCATC
AATGACCACCCTGATTTCAAAGGGATCAATCCAACTTCTGAAAATGTGGCTCGTTGGTTTTATTCTGGGTTAAAAGAAGA
AGTGAAGGCTTCGGACGGGAAAATTCAGAGGATTGTCATCCACGAAGGTCCAGAAAATTTGGCCTTCTTCGAACCAGAAA
CCTAG

Upstream 100 bases:

>100_bases
TCTTTAAAAAAGCGTGGTTTGGTTGATTCAGTCATCTTCTAGAGTCCCCTTAGAGGAAATTACTATACAAATATTGGACG
ATACTCTATTCGTCAATGGA

Downstream 100 bases:

>100_bases
GAATCGCCTTCTCCCATCCAATGGGGCGAAACCTAGGAAAATTGGATTCTTCTGGATTGTATTTAAAAGTCTTCTCCAAA
ACTTTTCGAAAACTCAACTG

Product: putative 6-pyruvoyl tetrahydrobiopterin synthase

Products: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; CMP

Alternate protein names: 6-Pyruvoyl Tetrahydrobiopterin Synthase; 6-Pyruvoyl-Tetrahydropterin Synthase; Queuosine Biosynthesis Protein QueD; Preq(0) Biosynthesis Protein Qued; 6-Pyruvoyltetrahydropterin Synthase; Queuosine Biosynthesis Protein

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MFTQENGKFYVRIEGRFESAHFLYQYFADGTDEPIHGHSWKVEVYLEGKTNIRPDGISYDFLTARNKLLALVHSIDHILI
NDHPDFKGINPTSENVARWFYSGLKEEVKASDGKIQRIVIHEGPENLAFFEPET

Sequences:

>Translated_134_residues
MFTQENGKFYVRIEGRFESAHFLYQYFADGTDEPIHGHSWKVEVYLEGKTNIRPDGISYDFLTARNKLLALVHSIDHILI
NDHPDFKGINPTSENVARWFYSGLKEEVKASDGKIQRIVIHEGPENLAFFEPET
>Mature_134_residues
MFTQENGKFYVRIEGRFESAHFLYQYFADGTDEPIHGHSWKVEVYLEGKTNIRPDGISYDFLTARNKLLALVHSIDHILI
NDHPDFKGINPTSENVARWFYSGLKEEVKASDGKIQRIVIHEGPENLAFFEPET

Specific function: Unknown

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.6.1.12

Molecular weight: Translated: 15501; Mature: 15501

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTQENGKFYVRIEGRFESAHFLYQYFADGTDEPIHGHSWKVEVYLEGKTNIRPDGISYD
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCH
FLTARNKLLALVHSIDHILINDHPDFKGINPTSENVARWFYSGLKEEVKASDGKIQRIVI
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HEGPENLAFFEPET
EECCCCCEEECCCC
>Mature Secondary Structure
MFTQENGKFYVRIEGRFESAHFLYQYFADGTDEPIHGHSWKVEVYLEGKTNIRPDGISYD
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCH
FLTARNKLLALVHSIDHILINDHPDFKGINPTSENVARWFYSGLKEEVKASDGKIQRIVI
HHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HEGPENLAFFEPET
EECCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

Specific reaction: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA