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The map label for this gene is yogA [H]

Identifier: 183222461

GI number: 183222461

Start: 3228895

End: 3229908

Strand: Reverse

Name: yogA [H]

Synonym: LEPBI_I3115

Alternate gene names: 183222461

Gene position: 3229908-3228895 (Counterclockwise)

Preceding gene: 183222462

Following gene: 183222458

Centisome position: 89.73

GC content: 44.38

Gene sequence:

>1014_bases
TTGATGAGACAAGCCGAGATCAAACAATTTGGATTGGATAATTTAAAAGTCATTGAGGTTCCAGAACCAAAAGAAGTAGG
TCCCACAGACGTATTGGTGCGACTGCATGCGGCCTCTCTCAATTACCGAGACTCTCTTGTTGTGGAAGGAAAGTACAACC
CCAAGTTTCCTTTACCACTCGTTCCCTGTAGTGATGGGGCCGGGGAAGTGATCCAAATTGGATCCCAAGTCACGGAATGG
AATGTGGGAGATAAAGTCCTTCTCACATTTGCGCCCAAATGGATCGCAAAAGAAGCAACACATTCAGAAATACGACACAC
CATTGGTGGGCCACTCCCAGGAACACTGAGAGAATTGGCGATAGTTCCCGAAACGGGTCTTGTTAAGATGCCATCGCATT
TAACCTTCGAAGAAGGTGCGACATTGCCATGTGCAGCACTCACCGCATGGTCCGGATTATTCCAATACAGCCAACTCAAA
CCTGGTGAGTTTGTCGTCGTACAGGGGACAGGTGGTGTTTCTATTTTTGCCTTACAATTTGCAAAATTAATGGGTGCGAA
AGTCATTTTAACATCGTCTAGTGATGAAAAACTCGATCGTGGAAAATCATTAGGCGCCGATTTTTTCATCAATTATAAAG
AGACCAAGGATTGGGGGAAAGAAGTTCGACGGATCACAAATAAAGTGGGTGCTGATCATATCATCGAAGTGGGTGGAGCA
GGGACATTGGAGCAATCCATTGCCGCCTGTCGGCCGTTTGGTGTGATCCATTTGATAGGAATTTTAGCTGGTCGTTCCGG
GGAACTCAATTTACTTCCAGCAGTCATGAACAATTTAAAAATCCAAGGACTAGTGGTGGGTGGGAGAAAAGCCTTTATTG
AAATGAACCAAGCCATCGAACAATCTGGATTAAAACCAGTCGTAGACAAAGTTTTCCCATTGGAAAACTCAGTGGAAGCC
ATCCAATACTTACGATCAGGTTCTCATTTTGGAAAAATTGTGATTACGATTTGA

Upstream 100 bases:

>100_bases
ACTTAGCCTATACTAAACTTGTGTTGGATCTATTTATAATTTCAAAATTTGAGATCTTGCATTTATATTTGATAACGAAC
TATTTGAAAGGAAGATTTGA

Downstream 100 bases:

>100_bases
TTTCTGTTGGAGATTCCAAAATGGATTTTGTTTCGATATCCAATGCATTGACTGACAAATGGATTTCAATGAGAGCCAAA
ATAAGAGAGACCACCATACA

Product: putative NADPH:quinone reductase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MMRQAEIKQFGLDNLKVIEVPEPKEVGPTDVLVRLHAASLNYRDSLVVEGKYNPKFPLPLVPCSDGAGEVIQIGSQVTEW
NVGDKVLLTFAPKWIAKEATHSEIRHTIGGPLPGTLRELAIVPETGLVKMPSHLTFEEGATLPCAALTAWSGLFQYSQLK
PGEFVVVQGTGGVSIFALQFAKLMGAKVILTSSSDEKLDRGKSLGADFFINYKETKDWGKEVRRITNKVGADHIIEVGGA
GTLEQSIAACRPFGVIHLIGILAGRSGELNLLPAVMNNLKIQGLVVGGRKAFIEMNQAIEQSGLKPVVDKVFPLENSVEA
IQYLRSGSHFGKIVITI

Sequences:

>Translated_337_residues
MMRQAEIKQFGLDNLKVIEVPEPKEVGPTDVLVRLHAASLNYRDSLVVEGKYNPKFPLPLVPCSDGAGEVIQIGSQVTEW
NVGDKVLLTFAPKWIAKEATHSEIRHTIGGPLPGTLRELAIVPETGLVKMPSHLTFEEGATLPCAALTAWSGLFQYSQLK
PGEFVVVQGTGGVSIFALQFAKLMGAKVILTSSSDEKLDRGKSLGADFFINYKETKDWGKEVRRITNKVGADHIIEVGGA
GTLEQSIAACRPFGVIHLIGILAGRSGELNLLPAVMNNLKIQGLVVGGRKAFIEMNQAIEQSGLKPVVDKVFPLENSVEA
IQYLRSGSHFGKIVITI
>Mature_337_residues
MMRQAEIKQFGLDNLKVIEVPEPKEVGPTDVLVRLHAASLNYRDSLVVEGKYNPKFPLPLVPCSDGAGEVIQIGSQVTEW
NVGDKVLLTFAPKWIAKEATHSEIRHTIGGPLPGTLRELAIVPETGLVKMPSHLTFEEGATLPCAALTAWSGLFQYSQLK
PGEFVVVQGTGGVSIFALQFAKLMGAKVILTSSSDEKLDRGKSLGADFFINYKETKDWGKEVRRITNKVGADHIIEVGGA
GTLEQSIAACRPFGVIHLIGILAGRSGELNLLPAVMNNLKIQGLVVGGRKAFIEMNQAIEQSGLKPVVDKVFPLENSVEA
IQYLRSGSHFGKIVITI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=329, Percent_Identity=24.6200607902736, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI194239674, Length=343, Percent_Identity=25.6559766763848, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI13236495, Length=343, Percent_Identity=25.6559766763848, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI22538446, Length=348, Percent_Identity=26.1494252873563, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI22538444, Length=348, Percent_Identity=26.1494252873563, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI194239676, Length=333, Percent_Identity=25.5255255255255, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI156627571, Length=323, Percent_Identity=26.9349845201238, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI28557745, Length=345, Percent_Identity=26.9565217391304, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI67078404, Length=211, Percent_Identity=30.3317535545024, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4501933, Length=350, Percent_Identity=24.2857142857143, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI34577061, Length=355, Percent_Identity=23.6619718309859, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI47519420, Length=352, Percent_Identity=25.2840909090909, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789651, Length=259, Percent_Identity=28.1853281853282, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790485, Length=273, Percent_Identity=26.7399267399267, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081918, Length=318, Percent_Identity=25.1572327044025, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790045, Length=332, Percent_Identity=23.7951807228916, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562584, Length=336, Percent_Identity=25.5952380952381, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988145, Length=336, Percent_Identity=24.1071428571429, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17507255, Length=324, Percent_Identity=26.5432098765432, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562876, Length=295, Percent_Identity=27.7966101694915, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562582, Length=297, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562878, Length=214, Percent_Identity=28.0373831775701, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17556000, Length=290, Percent_Identity=25.1724137931034, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=288, Percent_Identity=28.4722222222222, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6323729, Length=289, Percent_Identity=27.3356401384083, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=335, Percent_Identity=26.865671641791, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324486, Length=335, Percent_Identity=25.0746268656716, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319955, Length=307, Percent_Identity=26.3843648208469, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=259, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322619, Length=307, Percent_Identity=26.3843648208469, Blast_Score=73, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36461; Mature: 36461

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRQAEIKQFGLDNLKVIEVPEPKEVGPTDVLVRLHAASLNYRDSLVVEGKYNPKFPLPL
CCCHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEEEECCCCCCCCEEEECCCCCCCCCEE
VPCSDGAGEVIQIGSQVTEWNVGDKVLLTFAPKWIAKEATHSEIRHTIGGPLPGTLRELA
EECCCCCCHHHECCCHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHEE
IVPETGLVKMPSHLTFEEGATLPCAALTAWSGLFQYSQLKPGEFVVVQGTGGVSIFALQF
ECCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHH
AKLMGAKVILTSSSDEKLDRGKSLGADFFINYKETKDWGKEVRRITNKVGADHIIEVGGA
HHHCCCEEEEECCCCHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCC
GTLEQSIAACRPFGVIHLIGILAGRSGELNLLPAVMNNLKIQGLVVGGRKAFIEMNQAIE
CCHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHCCCEEEEEEECCHHHHHHHHHHHH
QSGLKPVVDKVFPLENSVEAIQYLRSGSHFGKIVITI
HCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MMRQAEIKQFGLDNLKVIEVPEPKEVGPTDVLVRLHAASLNYRDSLVVEGKYNPKFPLPL
CCCHHHHHHCCCCCEEEEECCCCCCCCCHHEEEEEEECCCCCCCCEEEECCCCCCCCCEE
VPCSDGAGEVIQIGSQVTEWNVGDKVLLTFAPKWIAKEATHSEIRHTIGGPLPGTLRELA
EECCCCCCHHHECCCHHEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHEE
IVPETGLVKMPSHLTFEEGATLPCAALTAWSGLFQYSQLKPGEFVVVQGTGGVSIFALQF
ECCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHH
AKLMGAKVILTSSSDEKLDRGKSLGADFFINYKETKDWGKEVRRITNKVGADHIIEVGGA
HHHCCCEEEEECCCCHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCC
GTLEQSIAACRPFGVIHLIGILAGRSGELNLLPAVMNNLKIQGLVVGGRKAFIEMNQAIE
CCHHHHHHHHCCHHHHHHHHHHCCCCCCCEEHHHHHCCCEEEEEEECCHHHHHHHHHHHH
QSGLKPVVDKVFPLENSVEAIQYLRSGSHFGKIVITI
HCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]