Click here to switch to the map view.

The map label for this gene is yaeL [C]

Identifier: 183221969

GI number: 183221969

Start: 2700674

End: 2702380

Strand: Reverse

Name: yaeL [C]

Synonym: LEPBI_I2610

Alternate gene names: 183221969

Gene position: 2702380-2700674 (Counterclockwise)

Preceding gene: 183221970

Following gene: 183221968

Centisome position: 75.07

GC content: 39.89

Gene sequence:

>1707_bases
ATGATCATAATGATACTTGGCGCTGTATTCATGTTGGCTGTATCGATTTTTATCCATGAATTGGGGCACCTCTTATGTGG
AAAATTGGTGGGCGTTGAAGCCCGCATATTTTCGTTAGGTTACGGAAAAGGGATTTGGAAAAAAAGGATTGGAAAAACCA
TCTACCAAATCACTGCCATCCCAGTGGGTGGTTATGTTTTGTTTCGTGGAGATGATTATAGCAAAAACAAAAAACCAAGG
CAAGGTGATTTGCTTGCCACACCTCCACTGCGAAGGATGATCCCTGTACTCGGTGGTCCTTTCGCCAATTTGGTGTTAGG
TTTTATATTATTGTTTATTTTAGAACTATCGGGTGATAGTCCTTCTTCGAATCGTATTTTCATAGAAGATGCAAATAAGG
TTGCAAGCCCCGCATACAGTGCTGGCCTTCGAACTGGTGATTTGATCCTTTCTGTAAATGGAAAACCAACAGAAAGTTTT
GAAGATATTTTCACCAATGTGAGTTTGACATCAGGGGATCCGATTGAAGTCACTTTCAAACGTGGCGAAGAAACCAAGTC
CGTTTCGATCGTTCCCAATTTGTATTCGGCTGGTGGACACCCGACCATTGGTGTCATGCCATACGGCGAAAGAAGGGTAG
TCGCAACCTTTACCTATGGAGAACAAATCGGCCATTTTATGGCAAATGTTTTAGATAAAGAAGACAAATCTTCAGCCTAT
TTCCAGGAAAAAATAGAAGAACGGAAAACGGAAATCCCAGAAGAACTTCTAAAACAACATGAAATCGCAGAACGGGAAAA
ATCGCTCAGACGTCGAGCTTTGTCTTTTTTAAAAGATGGAGACATGATCCTCACTGTAGCGGGTGTAGACGTTCATACGG
TTCCTGAATTACAAACAGAATTAGGAAAACACCAAGGAAAAACCATTCCTGTGGAAGTGGAACGAAAAACTTACCCACTC
CTCACACCTTGGGCAACTGAAAAAGTAACGATTCAAATTCCAGTGTTAGGTGCCAATGTATTTGAATTTTGGAATATTGA
ACACCCAAAATTTCCAGAATTGGCAATCCCTTATTTTCGATTGGATAGTTATGACGCTGAAATCGAAAATCGTCTCTCGA
ATTTAAAAATCCAGAACCAAATGTTTGATTCCTCTGATTCGTTAACCAACTATTTGAAAACGAATGTTGGCAGAAAAGAA
ATTTGGATTGGGAATATGAGATACTTCGCTGATGTGAATTTAAAACCCATTGGTTTACTTGGATTTCGAGCTTCCATGAA
ATTTGAAGCTGAAAAATTACAAAAGGAATCTACCGTATACTCTTCGTTTGTTGGTGCTGGAAATAAAGTGTATGAGAATG
TTTCCACAACCTTAAAAGGGATTGGGATGTTGTTTTCGGGTTTGTTGTCTCCAAAAGAAAATTTATCTGGACCCATCGGG
ATTGTGCAAATCGCAGGGATTAGTTTGGAATATGGTTGGGTGACCTACCTTGATTTTGTTGCTAAAATTTCGTTGGCACT
TATGGTCATGAATTTACTTCCCATCCCCATGGCTGACGGCGGACACATTGTACTCTATGCATATGAAGCTATCACAGGAA
GACCACTTCCTAGAAAAGCCATTGAAGCCATCTTCCGTTTGGGATTTTTCTTTCTCATCGGACTTGGTCTTTATGTATCC
TTTAATGATGTGATGCGTATTTTTTAA

Upstream 100 bases:

>100_bases
TTGAGAACGTATTTCCAGAAACGTTAGATGGGTATTTGGAAAAAGACCAAGAAACACGAAATTATATCCAAAGAGAATTT
AATCAAGGGGGAGTGACTAC

Downstream 100 bases:

>100_bases
AGTATACTTTGAATTGTTAGATTGTTAATCAAAAAGAGAAAATTGATATGAAAGCTAGTTCCTATTTAATCCCTACTGCC
AAAGAAGACCCACAAGATGC

Product: membrane-associated Zn-dependent metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MIIMILGAVFMLAVSIFIHELGHLLCGKLVGVEARIFSLGYGKGIWKKRIGKTIYQITAIPVGGYVLFRGDDYSKNKKPR
QGDLLATPPLRRMIPVLGGPFANLVLGFILLFILELSGDSPSSNRIFIEDANKVASPAYSAGLRTGDLILSVNGKPTESF
EDIFTNVSLTSGDPIEVTFKRGEETKSVSIVPNLYSAGGHPTIGVMPYGERRVVATFTYGEQIGHFMANVLDKEDKSSAY
FQEKIEERKTEIPEELLKQHEIAEREKSLRRRALSFLKDGDMILTVAGVDVHTVPELQTELGKHQGKTIPVEVERKTYPL
LTPWATEKVTIQIPVLGANVFEFWNIEHPKFPELAIPYFRLDSYDAEIENRLSNLKIQNQMFDSSDSLTNYLKTNVGRKE
IWIGNMRYFADVNLKPIGLLGFRASMKFEAEKLQKESTVYSSFVGAGNKVYENVSTTLKGIGMLFSGLLSPKENLSGPIG
IVQIAGISLEYGWVTYLDFVAKISLALMVMNLLPIPMADGGHIVLYAYEAITGRPLPRKAIEAIFRLGFFFLIGLGLYVS
FNDVMRIF

Sequences:

>Translated_568_residues
MIIMILGAVFMLAVSIFIHELGHLLCGKLVGVEARIFSLGYGKGIWKKRIGKTIYQITAIPVGGYVLFRGDDYSKNKKPR
QGDLLATPPLRRMIPVLGGPFANLVLGFILLFILELSGDSPSSNRIFIEDANKVASPAYSAGLRTGDLILSVNGKPTESF
EDIFTNVSLTSGDPIEVTFKRGEETKSVSIVPNLYSAGGHPTIGVMPYGERRVVATFTYGEQIGHFMANVLDKEDKSSAY
FQEKIEERKTEIPEELLKQHEIAEREKSLRRRALSFLKDGDMILTVAGVDVHTVPELQTELGKHQGKTIPVEVERKTYPL
LTPWATEKVTIQIPVLGANVFEFWNIEHPKFPELAIPYFRLDSYDAEIENRLSNLKIQNQMFDSSDSLTNYLKTNVGRKE
IWIGNMRYFADVNLKPIGLLGFRASMKFEAEKLQKESTVYSSFVGAGNKVYENVSTTLKGIGMLFSGLLSPKENLSGPIG
IVQIAGISLEYGWVTYLDFVAKISLALMVMNLLPIPMADGGHIVLYAYEAITGRPLPRKAIEAIFRLGFFFLIGLGLYVS
FNDVMRIF
>Mature_568_residues
MIIMILGAVFMLAVSIFIHELGHLLCGKLVGVEARIFSLGYGKGIWKKRIGKTIYQITAIPVGGYVLFRGDDYSKNKKPR
QGDLLATPPLRRMIPVLGGPFANLVLGFILLFILELSGDSPSSNRIFIEDANKVASPAYSAGLRTGDLILSVNGKPTESF
EDIFTNVSLTSGDPIEVTFKRGEETKSVSIVPNLYSAGGHPTIGVMPYGERRVVATFTYGEQIGHFMANVLDKEDKSSAY
FQEKIEERKTEIPEELLKQHEIAEREKSLRRRALSFLKDGDMILTVAGVDVHTVPELQTELGKHQGKTIPVEVERKTYPL
LTPWATEKVTIQIPVLGANVFEFWNIEHPKFPELAIPYFRLDSYDAEIENRLSNLKIQNQMFDSSDSLTNYLKTNVGRKE
IWIGNMRYFADVNLKPIGLLGFRASMKFEAEKLQKESTVYSSFVGAGNKVYENVSTTLKGIGMLFSGLLSPKENLSGPIG
IVQIAGISLEYGWVTYLDFVAKISLALMVMNLLPIPMADGGHIVLYAYEAITGRPLPRKAIEAIFRLGFFFLIGLGLYVS
FNDVMRIF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=157, Percent_Identity=33.7579617834395, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 63259; Mature: 63259

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIMILGAVFMLAVSIFIHELGHLLCGKLVGVEARIFSLGYGKGIWKKRIGKTIYQITAI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHCCCEEEEEEE
PVGGYVLFRGDDYSKNKKPRQGDLLATPPLRRMIPVLGGPFANLVLGFILLFILELSGDS
EECCEEEEECCCCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
PSSNRIFIEDANKVASPAYSAGLRTGDLILSVNGKPTESFEDIFTNVSLTSGDPIEVTFK
CCCCEEEEECCCHHCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHCCEECCCCCEEEEEE
RGEETKSVSIVPNLYSAGGHPTIGVMPYGERRVVATFTYGEQIGHFMANVLDKEDKSSAY
CCCCCCEEEEECCHHCCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHHHCCCCCCHHH
FQEKIEERKTEIPEELLKQHEIAEREKSLRRRALSFLKDGDMILTVAGVDVHTVPELQTE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCHHHHHH
LGKHQGKTIPVEVERKTYPLLTPWATEKVTIQIPVLGANVFEFWNIEHPKFPELAIPYFR
HHHHCCCCCEEEECCCCCCEECCCCCCEEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEE
LDSYDAEIENRLSNLKIQNQMFDSSDSLTNYLKTNVGRKEIWIGNMRYFADVNLKPIGLL
ECCCCHHHHHHHHCCEEHHHHCCCHHHHHHHHHHCCCCCEEEECCEEEEEECCCCEEEEE
GFRASMKFEAEKLQKESTVYSSFVGAGNKVYENVSTTLKGIGMLFSGLLSPKENLSGPIG
EECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEE
IVQIAGISLEYGWVTYLDFVAKISLALMVMNLLPIPMADGGHIVLYAYEAITGRPLPRKA
EEEEECEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCCCCCCHHH
IEAIFRLGFFFLIGLGLYVSFNDVMRIF
HHHHHHHHHHHHHHHHHHEEHHHHHHCC
>Mature Secondary Structure
MIIMILGAVFMLAVSIFIHELGHLLCGKLVGVEARIFSLGYGKGIWKKRIGKTIYQITAI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHCCCEEEEEEE
PVGGYVLFRGDDYSKNKKPRQGDLLATPPLRRMIPVLGGPFANLVLGFILLFILELSGDS
EECCEEEEECCCCCCCCCCCCCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
PSSNRIFIEDANKVASPAYSAGLRTGDLILSVNGKPTESFEDIFTNVSLTSGDPIEVTFK
CCCCEEEEECCCHHCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHCCEECCCCCEEEEEE
RGEETKSVSIVPNLYSAGGHPTIGVMPYGERRVVATFTYGEQIGHFMANVLDKEDKSSAY
CCCCCCEEEEECCHHCCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHHHCCCCCCHHH
FQEKIEERKTEIPEELLKQHEIAEREKSLRRRALSFLKDGDMILTVAGVDVHTVPELQTE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCHHHHHH
LGKHQGKTIPVEVERKTYPLLTPWATEKVTIQIPVLGANVFEFWNIEHPKFPELAIPYFR
HHHHCCCCCEEEECCCCCCEECCCCCCEEEEEEEEECCCHHHHCCCCCCCCCCCCCCEEE
LDSYDAEIENRLSNLKIQNQMFDSSDSLTNYLKTNVGRKEIWIGNMRYFADVNLKPIGLL
ECCCCHHHHHHHHCCEEHHHHCCCHHHHHHHHHHCCCCCEEEECCEEEEEECCCCEEEEE
GFRASMKFEAEKLQKESTVYSSFVGAGNKVYENVSTTLKGIGMLFSGLLSPKENLSGPIG
EECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCEE
IVQIAGISLEYGWVTYLDFVAKISLALMVMNLLPIPMADGGHIVLYAYEAITGRPLPRKA
EEEEECEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCCCCCCHHH
IEAIFRLGFFFLIGLGLYVSFNDVMRIF
HHHHHHHHHHHHHHHHHHEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]