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The map label for this gene is nuoE [H]

Identifier: 183220690

GI number: 183220690

Start: 1353998

End: 1354492

Strand: Direct

Name: nuoE [H]

Synonym: LEPBI_I1300

Alternate gene names: 183220690

Gene position: 1353998-1354492 (Clockwise)

Preceding gene: 183220689

Following gene: 183220691

Centisome position: 37.61

GC content: 41.21

Gene sequence:

>495_bases
TTGTTAATGGCGTATCAATTTTCACAAGAATCCGAAACAAGGTTCCAAAGGCTCATCCCACAATTCCCAAGCAAACGTTC
TCTCATTTTGCCCTGTTTATTTTTGTTACAAGCTGACAAGGGTTTTGTGGACACAGAAGGCATGCAGTACATTGCCGATC
GAATCGGCGAACCAGTGTCCTTAGCACACGTTCACGGTGTGGCAACCTTTTACACCATGTACAATAAAAAACCAGTTGGG
AAGTTCCACATCCAAATTTGTGCCAATATTTCCTGTTACCTGGCTGGTTCCGATTCCATCACAGAACATGTATGTTCCAA
ATTGGGAATGAAGAAGGGTGAAACCACAAAAGACAAAAAATACACCGTGGATGAAGTGCAGTGCCTCGGTGCTTGTGGAT
TTGGTCCTGTTGCCCAAATCAATGACAAATATTATGAAAATTTAACTCCAGAATCCATCGAAAAGATTCTTTCTGAATTG
GAAAAAGAAGGATAA

Upstream 100 bases:

>100_bases
TTTGGTACTACCAGGCATTTCCGGAAATGGTGAAAGGTGGTTTACTGGCGGATACTATCGCCACCATGTCATCGCTCAAT
GTCATCGCAGGGGAGCTTGA

Downstream 100 bases:

>100_bases
CATGGGACTAAAAACCTTACTTACAACTCATATTGATGCTTCTGATTCGCATACTTTGAAACACTACCAGTCGGTCGGCG
GATATGAAAGTCTAAAAAAG

Product: NADH-quinone oxidoreductase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MLMAYQFSQESETRFQRLIPQFPSKRSLILPCLFLLQADKGFVDTEGMQYIADRIGEPVSLAHVHGVATFYTMYNKKPVG
KFHIQICANISCYLAGSDSITEHVCSKLGMKKGETTKDKKYTVDEVQCLGACGFGPVAQINDKYYENLTPESIEKILSEL
EKEG

Sequences:

>Translated_164_residues
MLMAYQFSQESETRFQRLIPQFPSKRSLILPCLFLLQADKGFVDTEGMQYIADRIGEPVSLAHVHGVATFYTMYNKKPVG
KFHIQICANISCYLAGSDSITEHVCSKLGMKKGETTKDKKYTVDEVQCLGACGFGPVAQINDKYYENLTPESIEKILSEL
EKEG
>Mature_164_residues
MLMAYQFSQESETRFQRLIPQFPSKRSLILPCLFLLQADKGFVDTEGMQYIADRIGEPVSLAHVHGVATFYTMYNKKPVG
KFHIQICANISCYLAGSDSITEHVCSKLGMKKGETTKDKKYTVDEVQCLGACGFGPVAQINDKYYENLTPESIEKILSEL
EKEG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=159, Percent_Identity=45.9119496855346, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1788621, Length=154, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561328, Length=159, Percent_Identity=40.8805031446541, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859877, Length=163, Percent_Identity=39.8773006134969, Blast_Score=136, Evalue=6e-33,
Organism=Drosophila melanogaster, GI21355353, Length=163, Percent_Identity=31.2883435582822, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18430; Mature: 18430

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMAYQFSQESETRFQRLIPQFPSKRSLILPCLFLLQADKGFVDTEGMQYIADRIGEPVS
CCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCH
LAHVHGVATFYTMYNKKPVGKFHIQICANISCYLAGSDSITEHVCSKLGMKKGETTKDKK
HHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
YTVDEVQCLGACGFGPVAQINDKYYENLTPESIEKILSELEKEG
CCHHHHHHHHCCCCCCHHHHCHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLMAYQFSQESETRFQRLIPQFPSKRSLILPCLFLLQADKGFVDTEGMQYIADRIGEPVS
CCEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCH
LAHVHGVATFYTMYNKKPVGKFHIQICANISCYLAGSDSITEHVCSKLGMKKGETTKDKK
HHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
YTVDEVQCLGACGFGPVAQINDKYYENLTPESIEKILSELEKEG
CCHHHHHHHHCCCCCCHHHHCHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA