Click here to switch to the map view.

The map label for this gene is gap [H]

Identifier: 182680368

GI number: 182680368

Start: 3943324

End: 3944331

Strand: Reverse

Name: gap [H]

Synonym: Bind_3468

Alternate gene names: 182680368

Gene position: 3944331-3943324 (Counterclockwise)

Preceding gene: 182680376

Following gene: 182680367

Centisome position: 94.58

GC content: 58.23

Gene sequence:

>1008_bases
ATGGCGGTTAAAGTCGCGATCAATGGATTCGGTCGCATCGGGCGGAATGTCTTGCGGGCCATTGCCGAATCCGGTCGTAA
AGACATCGAAGTTGTCGCCATCAATGATCTCGGCCCCGTCGAAACCAACGCCCATCTGCTGCGCTTCGATTCCGTGCATG
GCCGTTTTCCGGGCGAGGTCAAGGTCGATGGCGATACGATCGATATCGGTTTCGGGCCGATCAAGGTCACGGCGGTTCGT
GATCCGCATGAATTGCCGCATGCCGCGCTGGGGATTGATGTTGCCCTCGAATGTACCGGCATTTTCACCGCCCGCGACAA
GGCGGCCGCGCATTTGAAGGCAGGCGCCAAGCGCGTGCTGGTTTCGGCCCCCGCCGACAATGCCGATCTCACCGTGGTCT
ATGGCGTCAATCACGACAAGCTGACCAAGGATCACCTCGTCGTTTCCAACGCCTCCTGCACCACCAATTGCCTCGCGCCC
GTCGCCAAGGTTCTGAATGAGGCGGTCGGCATCGAGCACGGCTTCATGACCACCGTGCATTCCTATACGGGCGATCAGCC
GACGCTCGACACGATGCATAAGGACCTTTACCGCGCCCGCGCCGCTGCTTTGTCGATGATTCCCACCACGACCGGTGCCG
CCAAGGCTGTCGGGCTCGTCTTGCCGGAACTCAATGGCAAGCTCGCCGGCTCGTCTGTCCGCGTTCCGACCCCCAATGTT
TCTGTCGTCGATTTCACCTTCGTCGCCAAACGGCCGACCACGGCGGAAGAGATCAATGCCGCGATAAAACAGGCCGCCAC
CCAGCATTTGAAGGGCATTCTTGGCTTCACCGAAAGCCCTAATGTCTCAATCGATTTCAACCATGATCCGCATTCCTCGG
TCTTCCATATGGATCAGACCAAGGTTCTGGAAGGCACCTTCGTGCGTATCCTCTCCTGGTATGACAACGAATGGGGCTTT
TCCAACCGGATGAGTGATACCGCTGTCGCAATCGGGAAGCTTATATGA

Upstream 100 bases:

>100_bases
GAATTTCTCGTCAAATGCTTGACGACTTGCTTGCGGGCACGTCATAAAAAGCAAAATGCGGCTCGCAATGGGCCGGTTCT
TGTGGAAAGGAGCTTATCGG

Downstream 100 bases:

>100_bases
CCAGAACCGTGCCAGCCTCGCCTTTCCCCACCCTCGACGATGTCGTCGTCACCGGCAAGCGCGTCCTCGTGCGGGTCGAT
CTCAACGTTCCGATGGATAA

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVKVAINGFGRIGRNVLRAIAESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPGEVKVDGDTIDIGFGPIKVTAVR
DPHELPHAALGIDVALECTGIFTARDKAAAHLKAGAKRVLVSAPADNADLTVVYGVNHDKLTKDHLVVSNASCTTNCLAP
VAKVLNEAVGIEHGFMTTVHSYTGDQPTLDTMHKDLYRARAAALSMIPTTTGAAKAVGLVLPELNGKLAGSSVRVPTPNV
SVVDFTFVAKRPTTAEEINAAIKQAATQHLKGILGFTESPNVSIDFNHDPHSSVFHMDQTKVLEGTFVRILSWYDNEWGF
SNRMSDTAVAIGKLI

Sequences:

>Translated_335_residues
MAVKVAINGFGRIGRNVLRAIAESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPGEVKVDGDTIDIGFGPIKVTAVR
DPHELPHAALGIDVALECTGIFTARDKAAAHLKAGAKRVLVSAPADNADLTVVYGVNHDKLTKDHLVVSNASCTTNCLAP
VAKVLNEAVGIEHGFMTTVHSYTGDQPTLDTMHKDLYRARAAALSMIPTTTGAAKAVGLVLPELNGKLAGSSVRVPTPNV
SVVDFTFVAKRPTTAEEINAAIKQAATQHLKGILGFTESPNVSIDFNHDPHSSVFHMDQTKVLEGTFVRILSWYDNEWGF
SNRMSDTAVAIGKLI
>Mature_334_residues
AVKVAINGFGRIGRNVLRAIAESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPGEVKVDGDTIDIGFGPIKVTAVRD
PHELPHAALGIDVALECTGIFTARDKAAAHLKAGAKRVLVSAPADNADLTVVYGVNHDKLTKDHLVVSNASCTTNCLAPV
AKVLNEAVGIEHGFMTTVHSYTGDQPTLDTMHKDLYRARAAALSMIPTTTGAAKAVGLVLPELNGKLAGSSVRVPTPNVS
VVDFTFVAKRPTTAEEINAAIKQAATQHLKGILGFTESPNVSIDFNHDPHSSVFHMDQTKVLEGTFVRILSWYDNEWGFS
NRMSDTAVAIGKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=326, Percent_Identity=49.3865030674847, Blast_Score=301, Evalue=8e-82,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=45.7055214723926, Blast_Score=273, Evalue=2e-73,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=49.1017964071856, Blast_Score=334, Evalue=5e-93,
Organism=Escherichia coli, GI1788079, Length=334, Percent_Identity=50, Blast_Score=310, Evalue=6e-86,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=49.2447129909366, Blast_Score=301, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=48.9425981873112, Blast_Score=301, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=49.8489425981873, Blast_Score=295, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=49.8489425981873, Blast_Score=295, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=51.5243902439024, Blast_Score=311, Evalue=7e-86,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=50.4477611940299, Blast_Score=310, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=50.7462686567164, Blast_Score=308, Evalue=9e-85,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=50.4615384615385, Blast_Score=297, Evalue=6e-81,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=50.4615384615385, Blast_Score=297, Evalue=6e-81,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=50.4615384615385, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=50.4615384615385, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=44, Blast_Score=266, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35783; Mature: 35652

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVAINGFGRIGRNVLRAIAESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPGEV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEE
KVDGDTIDIGFGPIKVTAVRDPHELPHAALGIDVALECTGIFTARDKAAAHLKAGAKRVL
EECCCEEEECCCCEEEEEECCCHHCCHHHCCEEEEEEEEEEEEECCHHHHHHHCCCEEEE
VSAPADNADLTVVYGVNHDKLTKDHLVVSNASCTTNCLAPVAKVLNEAVGIEHGFMTTVH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHEEEH
SYTGDQPTLDTMHKDLYRARAAALSMIPTTTGAAKAVGLVLPELNGKLAGSSVRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEECCCCEECCCEEECCCCCC
SVVDFTFVAKRPTTAEEINAAIKQAATQHLKGILGFTESPNVSIDFNHDPHSSVFHMDQT
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCH
KVLEGTFVRILSWYDNEWGFSNRMSDTAVAIGKLI
HHHHHHHEEHHHHHCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AVKVAINGFGRIGRNVLRAIAESGRKDIEVVAINDLGPVETNAHLLRFDSVHGRFPGEV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEE
KVDGDTIDIGFGPIKVTAVRDPHELPHAALGIDVALECTGIFTARDKAAAHLKAGAKRVL
EECCCEEEECCCCEEEEEECCCHHCCHHHCCEEEEEEEEEEEEECCHHHHHHHCCCEEEE
VSAPADNADLTVVYGVNHDKLTKDHLVVSNASCTTNCLAPVAKVLNEAVGIEHGFMTTVH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHEEEH
SYTGDQPTLDTMHKDLYRARAAALSMIPTTTGAAKAVGLVLPELNGKLAGSSVRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEECCCCEECCCEEECCCCCC
SVVDFTFVAKRPTTAEEINAAIKQAATQHLKGILGFTESPNVSIDFNHDPHSSVFHMDQT
EEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCH
KVLEGTFVRILSWYDNEWGFSNRMSDTAVAIGKLI
HHHHHHHEEHHHHHCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]