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The map label for this gene is chvG [H]

Identifier: 182680203

GI number: 182680203

Start: 3756679

End: 3758703

Strand: Reverse

Name: chvG [H]

Synonym: Bind_3301

Alternate gene names: 182680203

Gene position: 3758703-3756679 (Counterclockwise)

Preceding gene: 182680204

Following gene: 182680199

Centisome position: 90.13

GC content: 55.11

Gene sequence:

>2025_bases
ATGAAATCGATGCTGAAATCTCCAGCGATGATGGGCAAATGGCGTCCACCGCTCGCTTTGGTCGTGACCTGTCTTCTATG
TTTTGCTGTGGCCTTGCCACTGGGCGGCGTTTTTTTCTTTCGCATCTATGAAAATCAATTGGTGAGGCAGGCGGAAGCCG
AACTGATCGCGCAAAGCGCAGCGCTTGCGCCAGTCATCGCACGAGACATCGAAGCCGCCTTGCCAGCCGACACGCCCCTA
GGAGCCGCTGCGCCATTGGCAACTCCGACGCAGGAGGAGCCTTATCGCCCGATCATGCCGCATCTCGATCTCGCAGATAA
AGACCTCCTACCAAGCCGCCCGGATGCGCGCCCGCCGACAAGCCCTCCGGATCCCGCTCTTCTCGCGCTTGGCGTAAAAA
TTCTGCCCGATCTCCTTGCGATCCAGCGCACCACTTTAGCTGGCTTCCGGTTGCTCGATGCTGAGGGAACCGTCATTGCC
GGCCGTAACGAAATCGGTCTGTCGCTCGCTCATGTGGAGGAAATTGCGGCAGCCTTGAGAGGCGAATTTCGTTCCGTCAT
GCGCATGCGCATTTCGAAACATCCGCCGCCGCCGCTTTATTCGATGAGCCGTGGCACTGGCGTGCGCGTGTTTACTGCAA
TGCCTATCATTGTGCGCGATCATGTCACCGCCGTACTTTACGCCTCGCGCACGCCAGCGAATGTGTTCAAGAATCTCTAT
GAAGAGCGAAACAAAGTCATTCTCGCAAGTGTCTCAGTGATCCTGCTGACAGGCCTTGCAGGTTTTGTGTTTCATCGAAC
CATTACGCGCCCCGTGCGTGAACTCATCGCCCGAACACGCGCGATTTCTGCCGGAGATACTGCCGCCTTGCGGCCTCTGT
CCCATCACGGCACGGCAGAATTTGCCATGCTGTCACGAAGCTTTCTCGATATGGCGACGAGCCTCGCTCATCGCTCAGCT
TTCATCGCGACCTTTGCCGCCCATGTCTCACATGAGCTGAAGTCACCCCTGACATCAATAAAAGGCGCAGCCGAACTGTT
GCTTGACGATCTCGAAGCTAATCCCCAAACCATGGACGATAATGATCGGCGTCGCTTTCTCGATCATATTGTGGTCGATG
CGGCGCGTCTGACAGATCTCGTGAGCCGCCTGCGTGATCTCGCCCGTGCTGAAAACACGCCAATATCCGGCACAGCCACT
CTTGATCCTGTTTTGCAGGAGCTTCGAAAGCAATGGCCTCATCTGGAGATCAATGCGCAGGGTGATGTTCATCGACAGGC
GCGCATATCGACAGAAAACCTGCACATCATCCTTTCGCATCTGATCGACAATGCCACGCATCACGGCGCGAAAAAAGTTA
CCGTCGAAGCCTTTGCAGACAAGGAAATCCTGCAGATCACGATCAAGGATGACGGTAGCGGAATCTCACCGAATAATGCG
ACAAAAATCTTCGAGCCCTTCTTTACCACACGCCGCCTGGAAGGCGGCACAGGCATGGGGCTTTCAATTGTCCGCGCCAT
GATCGAAGCGCATAGCGGTTTTATCGATTGCCTTGATATAACAACCGGTGCAGCATTTGTGCTGAGGCTTCCTCTGGCGT
CTGGCGCAGAAAGCCTTTATGTGACGTACATCGGCTTGCGGCTTCGCCGGTTCTTGCTCTGCCTCATCGTCATTGCATCC
GGGCTCGCCTTACGCTGTTTCGGCGCTGACATTGGATTGCCTGTCGCTATCGTTAAATATGGCGGCTCGATTTTATGGGG
AGCGATGGTTTTCTTGCTGGCGGGAATGATCTTGGCACGCCAATCCCGATCGCAAATCGCATCCATTGCAGCCGTAATCG
CTCTCGTCGTCGAATTATCCAGGCTTTACCACACGCCGTGGCTCGACACCTTCCGCATCTCAACGGCGGGCGCCTTGCTA
TTGGGCCGGTTCTTTTCGATCTTCAATATCGTCGCTTACGGTGCCGGGATAATTCTCGGTCTCCTGATGGATAAGTTATG
TGAGAGAGATGCAGCAAGACTTTAG

Upstream 100 bases:

>100_bases
ATATCCGCAACATTCGCGCGAAGCTCGCTCTGGCTGGCGGCGGAGGATGTATCGAAACCGTGCATGGAATAGGATTCCGG
CTCGGCCCTTGCCAAGCATC

Downstream 100 bases:

>100_bases
CAATTGCCAGATATCCGCTCTGTGAGCAACTTCTAAGGATAGTCCTGGATATCTGAAAGCCTGCCTATGCATTTTGAAAA
TTCGCATCTGTCAATGGCTG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 674

Protein sequence:

>674_residues
MKSMLKSPAMMGKWRPPLALVVTCLLCFAVALPLGGVFFFRIYENQLVRQAEAELIAQSAALAPVIARDIEAALPADTPL
GAAAPLATPTQEEPYRPIMPHLDLADKDLLPSRPDARPPTSPPDPALLALGVKILPDLLAIQRTTLAGFRLLDAEGTVIA
GRNEIGLSLAHVEEIAAALRGEFRSVMRMRISKHPPPPLYSMSRGTGVRVFTAMPIIVRDHVTAVLYASRTPANVFKNLY
EERNKVILASVSVILLTGLAGFVFHRTITRPVRELIARTRAISAGDTAALRPLSHHGTAEFAMLSRSFLDMATSLAHRSA
FIATFAAHVSHELKSPLTSIKGAAELLLDDLEANPQTMDDNDRRRFLDHIVVDAARLTDLVSRLRDLARAENTPISGTAT
LDPVLQELRKQWPHLEINAQGDVHRQARISTENLHIILSHLIDNATHHGAKKVTVEAFADKEILQITIKDDGSGISPNNA
TKIFEPFFTTRRLEGGTGMGLSIVRAMIEAHSGFIDCLDITTGAAFVLRLPLASGAESLYVTYIGLRLRRFLLCLIVIAS
GLALRCFGADIGLPVAIVKYGGSILWGAMVFLLAGMILARQSRSQIASIAAVIALVVELSRLYHTPWLDTFRISTAGALL
LGRFFSIFNIVAYGAGIILGLLMDKLCERDAARL

Sequences:

>Translated_674_residues
MKSMLKSPAMMGKWRPPLALVVTCLLCFAVALPLGGVFFFRIYENQLVRQAEAELIAQSAALAPVIARDIEAALPADTPL
GAAAPLATPTQEEPYRPIMPHLDLADKDLLPSRPDARPPTSPPDPALLALGVKILPDLLAIQRTTLAGFRLLDAEGTVIA
GRNEIGLSLAHVEEIAAALRGEFRSVMRMRISKHPPPPLYSMSRGTGVRVFTAMPIIVRDHVTAVLYASRTPANVFKNLY
EERNKVILASVSVILLTGLAGFVFHRTITRPVRELIARTRAISAGDTAALRPLSHHGTAEFAMLSRSFLDMATSLAHRSA
FIATFAAHVSHELKSPLTSIKGAAELLLDDLEANPQTMDDNDRRRFLDHIVVDAARLTDLVSRLRDLARAENTPISGTAT
LDPVLQELRKQWPHLEINAQGDVHRQARISTENLHIILSHLIDNATHHGAKKVTVEAFADKEILQITIKDDGSGISPNNA
TKIFEPFFTTRRLEGGTGMGLSIVRAMIEAHSGFIDCLDITTGAAFVLRLPLASGAESLYVTYIGLRLRRFLLCLIVIAS
GLALRCFGADIGLPVAIVKYGGSILWGAMVFLLAGMILARQSRSQIASIAAVIALVVELSRLYHTPWLDTFRISTAGALL
LGRFFSIFNIVAYGAGIILGLLMDKLCERDAARL
>Mature_674_residues
MKSMLKSPAMMGKWRPPLALVVTCLLCFAVALPLGGVFFFRIYENQLVRQAEAELIAQSAALAPVIARDIEAALPADTPL
GAAAPLATPTQEEPYRPIMPHLDLADKDLLPSRPDARPPTSPPDPALLALGVKILPDLLAIQRTTLAGFRLLDAEGTVIA
GRNEIGLSLAHVEEIAAALRGEFRSVMRMRISKHPPPPLYSMSRGTGVRVFTAMPIIVRDHVTAVLYASRTPANVFKNLY
EERNKVILASVSVILLTGLAGFVFHRTITRPVRELIARTRAISAGDTAALRPLSHHGTAEFAMLSRSFLDMATSLAHRSA
FIATFAAHVSHELKSPLTSIKGAAELLLDDLEANPQTMDDNDRRRFLDHIVVDAARLTDLVSRLRDLARAENTPISGTAT
LDPVLQELRKQWPHLEINAQGDVHRQARISTENLHIILSHLIDNATHHGAKKVTVEAFADKEILQITIKDDGSGISPNNA
TKIFEPFFTTRRLEGGTGMGLSIVRAMIEAHSGFIDCLDITTGAAFVLRLPLASGAESLYVTYIGLRLRRFLLCLIVIAS
GLALRCFGADIGLPVAIVKYGGSILWGAMVFLLAGMILARQSRSQIASIAAVIALVVELSRLYHTPWLDTFRISTAGALL
LGRFFSIFNIVAYGAGIILGLLMDKLCERDAARL

Specific function: Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790346, Length=289, Percent_Identity=27.3356401384083, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=403, Percent_Identity=25.5583126550869, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1789808, Length=280, Percent_Identity=23.2142857142857, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=24.2105263157895, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=26.4822134387352, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI145693157, Length=282, Percent_Identity=27.3049645390071, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=304, Percent_Identity=23.3552631578947, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI87081816, Length=343, Percent_Identity=25.3644314868805, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=28.4518828451883, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1789149, Length=336, Percent_Identity=23.2142857142857, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI87082128, Length=306, Percent_Identity=24.5098039215686, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=24.2152466367713, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73280; Mature: 73280

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSMLKSPAMMGKWRPPLALVVTCLLCFAVALPLGGVFFFRIYENQLVRQAEAELIAQSA
CCHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAPVIARDIEAALPADTPLGAAAPLATPTQEEPYRPIMPHLDLADKDLLPSRPDARPPT
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPPDPALLALGVKILPDLLAIQRTTLAGFRLLDAEGTVIAGRNEIGLSLAHVEEIAAALR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEECCCCCCHHHHHHHHHHHHHH
GEFRSVMRMRISKHPPPPLYSMSRGTGVRVFTAMPIIVRDHVTAVLYASRTPANVFKNLY
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHEEEEECCCHHHHHHHHH
EERNKVILASVSVILLTGLAGFVFHRTITRPVRELIARTRAISAGDTAALRPLSHHGTAE
HHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHH
FAMLSRSFLDMATSLAHRSAFIATFAAHVSHELKSPLTSIKGAAELLLDDLEANPQTMDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NDRRRFLDHIVVDAARLTDLVSRLRDLARAENTPISGTATLDPVLQELRKQWPHLEINAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEECC
GDVHRQARISTENLHIILSHLIDNATHHGAKKVTVEAFADKEILQITIKDDGSGISPNNA
CCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHCCCEEEEEEEECCCCCCCCCCC
TKIFEPFFTTRRLEGGTGMGLSIVRAMIEAHSGFIDCLDITTGAAFVLRLPLASGAESLY
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEHHHCHHHHHHCCCCCCCCCHHH
VTYIGLRLRRFLLCLIVIASGLALRCFGADIGLPVAIVKYGGSILWGAMVFLLAGMILAR
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
QSRSQIASIAAVIALVVELSRLYHTPWLDTFRISTAGALLLGRFFSIFNIVAYGAGIILG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMDKLCERDAARL
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKSMLKSPAMMGKWRPPLALVVTCLLCFAVALPLGGVFFFRIYENQLVRQAEAELIAQSA
CCHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAPVIARDIEAALPADTPLGAAAPLATPTQEEPYRPIMPHLDLADKDLLPSRPDARPPT
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPPDPALLALGVKILPDLLAIQRTTLAGFRLLDAEGTVIAGRNEIGLSLAHVEEIAAALR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEEECCCCCCHHHHHHHHHHHHHH
GEFRSVMRMRISKHPPPPLYSMSRGTGVRVFTAMPIIVRDHVTAVLYASRTPANVFKNLY
HHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHEEEEECCCHHHHHHHHH
EERNKVILASVSVILLTGLAGFVFHRTITRPVRELIARTRAISAGDTAALRPLSHHGTAE
HHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHH
FAMLSRSFLDMATSLAHRSAFIATFAAHVSHELKSPLTSIKGAAELLLDDLEANPQTMDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NDRRRFLDHIVVDAARLTDLVSRLRDLARAENTPISGTATLDPVLQELRKQWPHLEINAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEECC
GDVHRQARISTENLHIILSHLIDNATHHGAKKVTVEAFADKEILQITIKDDGSGISPNNA
CCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHCCCEEEEEEEECCCCCCCCCCC
TKIFEPFFTTRRLEGGTGMGLSIVRAMIEAHSGFIDCLDITTGAAFVLRLPLASGAESLY
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEHHHCHHHHHHCCCCCCCCCHHH
VTYIGLRLRRFLLCLIVIASGLALRCFGADIGLPVAIVKYGGSILWGAMVFLLAGMILAR
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHH
QSRSQIASIAAVIALVVELSRLYHTPWLDTFRISTAGALLLGRFFSIFNIVAYGAGIILG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMDKLCERDAARL
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407839; 11743193; 11743194 [H]