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The map label for this gene is nuoD1

Identifier: 182679350

GI number: 182679350

Start: 2737160

End: 2738350

Strand: Reverse

Name: nuoD1

Synonym: Bind_2396

Alternate gene names: 182679350

Gene position: 2738350-2737160 (Counterclockwise)

Preceding gene: 182679351

Following gene: 182679349

Centisome position: 65.67

GC content: 57.6

Gene sequence:

>1191_bases
ATGAACGATAATCCGGTCCGCAATTTCGCGATCAATTTCGGCCCCCAGCATCCGGCGGCGCATGGCGTGTTGCGGCTCGT
GCTCGAACTCGACGGCGAAGTGGTCGAGCGTGTCGATCCGCATATCGGCCTCCTGCACCGGGGTACTGAGAAGCTGATGG
AGGCGCGTACCTATCTGCAGAACGTGCCTTATTTCGATCGGCTCGATTATGTCGCGCCGATGAATCAGGAACATGCCTTC
TGCCTCGCCATTGAGAAGCTGCTTGGCATCGAAGTCCCGCGCCGTGGGCAATTGCTGCGGGTTCTGTGGTGTGAAATCGG
CCGCATTCTCTCGCATCTTCTCAATGTCACGACGCAGGCCATGGACGTTGGCGCTCTGACGCCACCGCTCTGGGGCTTTG
AGGAACGCGAAAAGCTGATGGTCTTCTATGAGCGGGCCTCCGGCGCGCGCATGCATGCCAATTATTTCCGGCCGGGCGGC
GTGCATATCGATTGTCCGCAGCAGCTCATTGATGATATTGGCGCCTGGTGCGATCCCTTCCTGAAGGTCTGCGATGATCT
CAATGATCTCTTCATTGAGAATCGCATTTTCAAGCAGCGCAATGTCGATATTGGCGTCATCAGCCTCGAGGATTGCTGGC
GCTGGGGTTTTTCGGGCGTCATGGTGCGCGGCTCGGGCGCCGCTTGGGATTTGCGCAAGGCGCAGCCCTATGAATGCTAC
GAGGAAATGGATTTCGACATTCCCGTTGGCCGGCATGGCGATAATTATGATCGCCAGGTGATCCGCATGGAAGAAATGCG
GCAATCGACGAAAATCATGAAGCAATGCGTCGAGAAGCTCTCGCAGGCGAGTGGCAAGGGGCCCGTCGCCACGCCGCAGC
ACAAGGTCGTGCCGCCCTCGCGCGCCGAAATGAAGCGCTCGATGGAAGCTCTGATCCATCATTTCAAGCTTTATACCGAA
GGTTTCCACGTTCCAGCCGGCGAAGTCTATTGTGGTGTCGAAGCGCCCAAGGGTGAATTCGGCGTCTATCTCGTCTCGGA
CGGCACCGACAAACCCTATCGGTGCAAGATCAGGGCCCCCGGTTTCGCGCATCTATCGGCCATGGATTTTCTCTGCCGTA
AATCCATGCTCGCCGATGTCAGCGCCATTTTGGGTTCGCTCGACATCGTGTTCGGCGAGGTCGATCGATGA

Upstream 100 bases:

>100_bases
TCGACTACATCCTGCCGGGTGATGAGAAGGTCAAACATAATCCTCAATGAATCGATGCCTCATCGAGGCATGGCTCGCCT
GAGAATCATGAGCGAATATC

Downstream 100 bases:

>100_bases
GCTTTGCGGCCCGTAAGACAATTTTCCAAGAGGTGCACGCATGAGTAACCGCCGCTTGGCCGAAATCCAGCCAGACTCTT
TTGCCTTCACGCCGGAAAGC

Product: NADH dehydrogenase I, D subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D 1; NDH-1 subunit D 1

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNDNPVRNFAINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARTYLQNVPYFDRLDYVAPMNQEHAF
CLAIEKLLGIEVPRRGQLLRVLWCEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERASGARMHANYFRPGG
VHIDCPQQLIDDIGAWCDPFLKVCDDLNDLFIENRIFKQRNVDIGVISLEDCWRWGFSGVMVRGSGAAWDLRKAQPYECY
EEMDFDIPVGRHGDNYDRQVIRMEEMRQSTKIMKQCVEKLSQASGKGPVATPQHKVVPPSRAEMKRSMEALIHHFKLYTE
GFHVPAGEVYCGVEAPKGEFGVYLVSDGTDKPYRCKIRAPGFAHLSAMDFLCRKSMLADVSAILGSLDIVFGEVDR

Sequences:

>Translated_396_residues
MNDNPVRNFAINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARTYLQNVPYFDRLDYVAPMNQEHAF
CLAIEKLLGIEVPRRGQLLRVLWCEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERASGARMHANYFRPGG
VHIDCPQQLIDDIGAWCDPFLKVCDDLNDLFIENRIFKQRNVDIGVISLEDCWRWGFSGVMVRGSGAAWDLRKAQPYECY
EEMDFDIPVGRHGDNYDRQVIRMEEMRQSTKIMKQCVEKLSQASGKGPVATPQHKVVPPSRAEMKRSMEALIHHFKLYTE
GFHVPAGEVYCGVEAPKGEFGVYLVSDGTDKPYRCKIRAPGFAHLSAMDFLCRKSMLADVSAILGSLDIVFGEVDR
>Mature_396_residues
MNDNPVRNFAINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARTYLQNVPYFDRLDYVAPMNQEHAF
CLAIEKLLGIEVPRRGQLLRVLWCEIGRILSHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERASGARMHANYFRPGG
VHIDCPQQLIDDIGAWCDPFLKVCDDLNDLFIENRIFKQRNVDIGVISLEDCWRWGFSGVMVRGSGAAWDLRKAQPYECY
EEMDFDIPVGRHGDNYDRQVIRMEEMRQSTKIMKQCVEKLSQASGKGPVATPQHKVVPPSRAEMKRSMEALIHHFKLYTE
GFHVPAGEVYCGVEAPKGEFGVYLVSDGTDKPYRCKIRAPGFAHLSAMDFLCRKSMLADVSAILGSLDIVFGEVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=395, Percent_Identity=60.7594936708861, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI260898743, Length=389, Percent_Identity=59.8971722365039, Blast_Score=481, Evalue=1e-136,
Organism=Escherichia coli, GI145693162, Length=387, Percent_Identity=38.2428940568475, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1789076, Length=391, Percent_Identity=25.3196930946292, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788832, Length=389, Percent_Identity=25.1928020565553, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17555284, Length=391, Percent_Identity=60.8695652173913, Blast_Score=501, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17568379, Length=391, Percent_Identity=59.846547314578, Blast_Score=498, Evalue=1e-141,
Organism=Drosophila melanogaster, GI24638644, Length=394, Percent_Identity=60.1522842639594, Blast_Score=510, Evalue=1e-145,
Organism=Drosophila melanogaster, GI221459469, Length=394, Percent_Identity=54.0609137055838, Blast_Score=453, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD1_BEII9 (B2IHW4)

Other databases:

- EMBL:   CP001016
- RefSeq:   YP_001833496.1
- GeneID:   6200274
- GenomeReviews:   CP001016_GR
- KEGG:   bid:Bind_2396
- HOGENOM:   HBG459705
- OMA:   RNFAINF
- ProtClustDB:   CLSK2405715
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 44950; Mature: 44950

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00535 COMPLEX1_49K; PS00503 PECTINESTERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNPVRNFAINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARTYLQ
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
NVPYFDRLDYVAPMNQEHAFCLAIEKLLGIEVPRRGQLLRVLWCEIGRILSHLLNVTTQA
CCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MDVGALTPPLWGFEEREKLMVFYERASGARMHANYFRPGGVHIDCPQQLIDDIGAWCDPF
HHCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHH
LKVCDDLNDLFIENRIFKQRNVDIGVISLEDCWRWGFSGVMVRGSGAAWDLRKAQPYECY
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHH
EEMDFDIPVGRHGDNYDRQVIRMEEMRQSTKIMKQCVEKLSQASGKGPVATPQHKVVPPS
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
RAEMKRSMEALIHHFKLYTEGFHVPAGEVYCGVEAPKGEFGVYLVSDGTDKPYRCKIRAP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCEEEEEECC
GFAHLSAMDFLCRKSMLADVSAILGSLDIVFGEVDR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure
MNDNPVRNFAINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEARTYLQ
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
NVPYFDRLDYVAPMNQEHAFCLAIEKLLGIEVPRRGQLLRVLWCEIGRILSHLLNVTTQA
CCCCHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MDVGALTPPLWGFEEREKLMVFYERASGARMHANYFRPGGVHIDCPQQLIDDIGAWCDPF
HHCCCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCEEECCHHHHHHHHHHHHHHH
LKVCDDLNDLFIENRIFKQRNVDIGVISLEDCWRWGFSGVMVRGSGAAWDLRKAQPYECY
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHH
EEMDFDIPVGRHGDNYDRQVIRMEEMRQSTKIMKQCVEKLSQASGKGPVATPQHKVVPPS
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
RAEMKRSMEALIHHFKLYTEGFHVPAGEVYCGVEAPKGEFGVYLVSDGTDKPYRCKIRAP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCEEEEEECC
GFAHLSAMDFLCRKSMLADVSAILGSLDIVFGEVDR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA