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The map label for this gene is nuoC [H]

Identifier: 182679351

GI number: 182679351

Start: 2738401

End: 2739039

Strand: Reverse

Name: nuoC [H]

Synonym: Bind_2397

Alternate gene names: 182679351

Gene position: 2739039-2738401 (Counterclockwise)

Preceding gene: 182679352

Following gene: 182679350

Centisome position: 65.68

GC content: 54.93

Gene sequence:

>639_bases
ATGGATAATGATCGTCGGGAATTGCTGCATCAGGAATTGACGCGGCAGGGCGAGGCGATTGGCGCGGCCCTGCCTGGAGC
GATAAAAGCTGCCACGGTCGCCTTCGGTGAATTGACCTTGACGGTCGAAGCCGGTCGCCTGATCGAAACAATCACTTATT
TGCGTGATGATCCGAGCGCTTTGTATGTGTCCTTCATCGATCTGACGGCGGTGGATTATCCCTTGCGGGAACGGCGTTTC
GATGTCGTGACGCATCTCTTATCGCCGAAACATAATCGCCGGATCCGCATCAAGGTGGAAACCGACGAGAATACGCCCGT
TCCTTCGTTGTCCTCGTTCTATCCCGCAGCCAATTGGTTCGAACGCGAGGCTTACGACTTTTTCGGTGTCTTGTTTTCCG
GCCATCCCGACTTGCGGCGCCTGCTGACCGATTATGGTTTCGACGGTCATCCCCTGCGCAAGGATTTTCCGATGACCGGC
TATGCCGAGGTCCGTTACGACGACGAACAGAAGCGTGTCGTCTACGAACCCGTGCAACTGGTTCAGGAGTTCCGCAGTTT
CGATTTTCTGTCTCCCTGGGAAGGCGCGATCGACTACATCCTGCCGGGTGATGAGAAGGTCAAACATAATCCTCAATGA

Upstream 100 bases:

>100_bases
TGCAGAAAAAGATCCGCCGTACAGGCACGATCGAACGATAAGAGCCCATCTTGCGCCATGATCTTTCACCATGGCGCAAG
ATATCCTCGAGGAAGATGCG

Downstream 100 bases:

>100_bases
ATCGATGCCTCATCGAGGCATGGCTCGCCTGAGAATCATGAGCGAATATCATGAACGATAATCCGGTCCGCAATTTCGCG
ATCAATTTCGGCCCCCAGCA

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MDNDRRELLHQELTRQGEAIGAALPGAIKAATVAFGELTLTVEAGRLIETITYLRDDPSALYVSFIDLTAVDYPLRERRF
DVVTHLLSPKHNRRIRIKVETDENTPVPSLSSFYPAANWFEREAYDFFGVLFSGHPDLRRLLTDYGFDGHPLRKDFPMTG
YAEVRYDDEQKRVVYEPVQLVQEFRSFDFLSPWEGAIDYILPGDEKVKHNPQ

Sequences:

>Translated_212_residues
MDNDRRELLHQELTRQGEAIGAALPGAIKAATVAFGELTLTVEAGRLIETITYLRDDPSALYVSFIDLTAVDYPLRERRF
DVVTHLLSPKHNRRIRIKVETDENTPVPSLSSFYPAANWFEREAYDFFGVLFSGHPDLRRLLTDYGFDGHPLRKDFPMTG
YAEVRYDDEQKRVVYEPVQLVQEFRSFDFLSPWEGAIDYILPGDEKVKHNPQ
>Mature_212_residues
MDNDRRELLHQELTRQGEAIGAALPGAIKAATVAFGELTLTVEAGRLIETITYLRDDPSALYVSFIDLTAVDYPLRERRF
DVVTHLLSPKHNRRIRIKVETDENTPVPSLSSFYPAANWFEREAYDFFGVLFSGHPDLRRLLTDYGFDGHPLRKDFPMTG
YAEVRYDDEQKRVVYEPVQLVQEFRSFDFLSPWEGAIDYILPGDEKVKHNPQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=192, Percent_Identity=53.125, Blast_Score=216, Evalue=1e-56,
Organism=Escherichia coli, GI145693162, Length=141, Percent_Identity=38.2978723404255, Blast_Score=97, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=195, Percent_Identity=44.1025641025641, Blast_Score=180, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI32563621, Length=195, Percent_Identity=44.1025641025641, Blast_Score=180, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24656494, Length=179, Percent_Identity=48.0446927374302, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 24438; Mature: 24438

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNDRRELLHQELTRQGEAIGAALPGAIKAATVAFGELTLTVEAGRLIETITYLRDDPSA
CCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHEEEEEEEEEEECCHHHHHHHHHCCCCCE
LYVSFIDLTAVDYPLRERRFDVVTHLLSPKHNRRIRIKVETDENTPVPSLSSFYPAANWF
EEEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHCCCHHHH
EREAYDFFGVLFSGHPDLRRLLTDYGFDGHPLRKDFPMTGYAEVRYDDEQKRVVYEPVQL
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
VQEFRSFDFLSPWEGAIDYILPGDEKVKHNPQ
HHHHHHCCCCCCCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MDNDRRELLHQELTRQGEAIGAALPGAIKAATVAFGELTLTVEAGRLIETITYLRDDPSA
CCCHHHHHHHHHHHHCCCHHHHCCCCHHHHHHEEEEEEEEEEECCHHHHHHHHHCCCCCE
LYVSFIDLTAVDYPLRERRFDVVTHLLSPKHNRRIRIKVETDENTPVPSLSSFYPAANWF
EEEEEHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHCCCHHHH
EREAYDFFGVLFSGHPDLRRLLTDYGFDGHPLRKDFPMTGYAEVRYDDEQKRVVYEPVQL
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
VQEFRSFDFLSPWEGAIDYILPGDEKVKHNPQ
HHHHHHCCCCCCCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA