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The map label for this gene is hisZ [H]

Identifier: 182678746

GI number: 182678746

Start: 2012027

End: 2013166

Strand: Reverse

Name: hisZ [H]

Synonym: Bind_1775

Alternate gene names: 182678746

Gene position: 2013166-2012027 (Counterclockwise)

Preceding gene: 182678747

Following gene: 182678745

Centisome position: 48.28

GC content: 60.96

Gene sequence:

>1140_bases
GTGCCCGTTTCCTCTCCCTCTCTTATCGATGAGCCGCTCTTCGAGATGGCGGTCGCCGCTCGCCTTGTTGCCGCTGGTTA
TCCGCGTTGCGAGCCAAAAATCCTGCAACCAGCCGCGATTTTCTTCGATTCGGGGGAGGATTTGCGCGGCCAACTTTATC
TAACGAGTGATATTTCCGGCGCTGATTATTGCCTACGGCCTGAATATACTATTCCGGTTTCCCGCCTTTATCTCGACTCT
CCGCAGGCTGGCTCGAGCGCCGGGTTTTCCTATTGCGGGCCGGTTTTCCGCTATCGCGGCGAACGGCCGAGCGAGTTCAT
CCAGGCTGGGATCGAAAGTTTCGGCCGGCAGGATCGCGAAGCCGCTGATGCCGAAATTTTGGGCCTGGCGCTGGAAGCTG
TTGGCGACTTCGCCGAGCGTCTTTCCGTTCGTATTACCGATGTCGGGCTGTTCACCGCTCTTCTCGACGCGCTGGAATTG
CCGCCTCCCTGGCGGCGGCGGCTTTTGCGGGCGCAGGTTCTTGGCACGCCGTTCGACATGATTTTTGCCCCCACGGGGGA
GAGCACGCAAACCGACCATTCTGGCGTGCTTGCGCTTCTCGATGGTGCCGACCGCCAGGGTGCGCGCGCGCTCGTCGAGG
ATTTGCTCTCCATAGCGGGATTTGCCTCCATCAGCGGGCGCACGCCGGCCGAGATCGCTGATCGTTTTCTCGAACAGGCT
GCCTTGAAATCGAGCCAGGGACTGGCATCTGAAAAGCGGCAGATTATCGAGCGCTTCCTCGCCATCGAGGGGGATCCTGA
CCAGGCCTCGGAGGCCATGCGCCGTCTCCTGTCGGAGGCGGGTCTCGACCTGACGAGCATTCTCGACAGTTTCGATGCGC
GGCTCGGCTTTATCGCCGCGCGCGGTCTCGATGTTTCGAGCCTGCATTTCGCGACGCGCTTCACCCGCAATCTGGATTAT
TATACGGGCTTCGTCTTCGAGGCGCATGATCGGCTGCGGCCGCAGGAAAAGCCCGTCATTGGCGGCGGCCGTTACGACAA
ATTATTGCGTCAACTGGGCGCGCCGCAGGATATTTCAGCGGTCGGCGCGGCGATCTGGATCGAGGCGCTTGACGCCATGA
ACAAGGGCGGAGCCGCTTGA

Upstream 100 bases:

>100_bases
TCTCCATCTTTGAAGAGAAAACGACATAATTTCTTTTCAAGAGAGAAAAGCATCCGGCCACATGGCATAAAGCAACTTGG
CCTCGCGACGAGAACAGACC

Downstream 100 bases:

>100_bases
TGAGTGAGATGCAGGCACCGCTCGTTCTGGCTGTCCCCTCCAAGGGGCGTTTACAGGAAAATGTCGCGGCCTTCTTCGCA
CGCGCCGGGCTCAGCCTCGT

Product: tRNA synthetase class II (G H P and S)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MPVSSPSLIDEPLFEMAVAARLVAAGYPRCEPKILQPAAIFFDSGEDLRGQLYLTSDISGADYCLRPEYTIPVSRLYLDS
PQAGSSAGFSYCGPVFRYRGERPSEFIQAGIESFGRQDREAADAEILGLALEAVGDFAERLSVRITDVGLFTALLDALEL
PPPWRRRLLRAQVLGTPFDMIFAPTGESTQTDHSGVLALLDGADRQGARALVEDLLSIAGFASISGRTPAEIADRFLEQA
ALKSSQGLASEKRQIIERFLAIEGDPDQASEAMRRLLSEAGLDLTSILDSFDARLGFIAARGLDVSSLHFATRFTRNLDY
YTGFVFEAHDRLRPQEKPVIGGGRYDKLLRQLGAPQDISAVGAAIWIEALDAMNKGGAA

Sequences:

>Translated_379_residues
MPVSSPSLIDEPLFEMAVAARLVAAGYPRCEPKILQPAAIFFDSGEDLRGQLYLTSDISGADYCLRPEYTIPVSRLYLDS
PQAGSSAGFSYCGPVFRYRGERPSEFIQAGIESFGRQDREAADAEILGLALEAVGDFAERLSVRITDVGLFTALLDALEL
PPPWRRRLLRAQVLGTPFDMIFAPTGESTQTDHSGVLALLDGADRQGARALVEDLLSIAGFASISGRTPAEIADRFLEQA
ALKSSQGLASEKRQIIERFLAIEGDPDQASEAMRRLLSEAGLDLTSILDSFDARLGFIAARGLDVSSLHFATRFTRNLDY
YTGFVFEAHDRLRPQEKPVIGGGRYDKLLRQLGAPQDISAVGAAIWIEALDAMNKGGAA
>Mature_378_residues
PVSSPSLIDEPLFEMAVAARLVAAGYPRCEPKILQPAAIFFDSGEDLRGQLYLTSDISGADYCLRPEYTIPVSRLYLDSP
QAGSSAGFSYCGPVFRYRGERPSEFIQAGIESFGRQDREAADAEILGLALEAVGDFAERLSVRITDVGLFTALLDALELP
PPWRRRLLRAQVLGTPFDMIFAPTGESTQTDHSGVLALLDGADRQGARALVEDLLSIAGFASISGRTPAEIADRFLEQAA
LKSSQGLASEKRQIIERFLAIEGDPDQASEAMRRLLSEAGLDLTSILDSFDARLGFIAARGLDVSSLHFATRFTRNLDYY
TGFVFEAHDRLRPQEKPVIGGGRYDKLLRQLGAPQDISAVGAAIWIEALDAMNKGGAA

Specific function: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine [H]

COG id: COG3705

COG function: function code E; ATP phosphoribosyltransferase involved in histidine biosynthesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004516 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41137; Mature: 41006

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSSPSLIDEPLFEMAVAARLVAAGYPRCEPKILQPAAIFFDSGEDLRGQLYLTSDISG
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEECCCCCCCEEEEEEECCCC
ADYCLRPEYTIPVSRLYLDSPQAGSSAGFSYCGPVFRYRGERPSEFIQAGIESFGRQDRE
CCEEECCCCCCCHHHEEECCCCCCCCCCCHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHH
AADAEILGLALEAVGDFAERLSVRITDVGLFTALLDALELPPPWRRRLLRAQVLGTPFDM
HHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHE
IFAPTGESTQTDHSGVLALLDGADRQGARALVEDLLSIAGFASISGRTPAEIADRFLEQA
EEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALKSSQGLASEKRQIIERFLAIEGDPDQASEAMRRLLSEAGLDLTSILDSFDARLGFIAA
HHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
RGLDVSSLHFATRFTRNLDYYTGFVFEAHDRLRPQEKPVIGGGRYDKLLRQLGAPQDISA
CCCCHHHHHHHHHHHHCCHHHHCEEEECHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHH
VGAAIWIEALDAMNKGGAA
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PVSSPSLIDEPLFEMAVAARLVAAGYPRCEPKILQPAAIFFDSGEDLRGQLYLTSDISG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEECCCCCCCEEEEEEECCCC
ADYCLRPEYTIPVSRLYLDSPQAGSSAGFSYCGPVFRYRGERPSEFIQAGIESFGRQDRE
CCEEECCCCCCCHHHEEECCCCCCCCCCCHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHH
AADAEILGLALEAVGDFAERLSVRITDVGLFTALLDALELPPPWRRRLLRAQVLGTPFDM
HHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHE
IFAPTGESTQTDHSGVLALLDGADRQGARALVEDLLSIAGFASISGRTPAEIADRFLEQA
EEECCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALKSSQGLASEKRQIIERFLAIEGDPDQASEAMRRLLSEAGLDLTSILDSFDARLGFIAA
HHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
RGLDVSSLHFATRFTRNLDYYTGFVFEAHDRLRPQEKPVIGGGRYDKLLRQLGAPQDISA
CCCCHHHHHHHHHHHHCCHHHHCEEEECHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHH
VGAAIWIEALDAMNKGGAA
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA