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The map label for this gene is etfB [H]

Identifier: 182678725

GI number: 182678725

Start: 1983478

End: 1984227

Strand: Reverse

Name: etfB [H]

Synonym: Bind_1752

Alternate gene names: 182678725

Gene position: 1984227-1983478 (Counterclockwise)

Preceding gene: 182678726

Following gene: 182678724

Centisome position: 47.58

GC content: 53.73

Gene sequence:

>750_bases
ATGAAGGTGCTCGTCCCAATAAAGCGGGTCGTTGATTACAATGTCAAGATACGGGTCAAAGCGGATCATTCTGGCGTTGA
AACAGCTAATGTCAAATATTCCGCGAACCCTTTCGACGAAATCGCCGTCGAGGAGGCCGTGCGGCTCAAAGAGGCCGGAA
TCGTTTCTGAGATTGTGGTTGTATCCATAGGAGCCGCCGCGGCTCAGGATGTCCTCCGCAATGCGCTCGCCCTAGGCGCC
GATCGTGCAATATTGGTGCAGACCGATCATGAGATCCAGCCATTGGCGGTCGCCAAGCTTCTCAAGCTCTTGTGTCTGCA
GGAGTCACCTCAGCTTGTCATTCTTGGCAAACAAGCCATCGATGATGATTCAAATCAGACCGGCCAAGCGTTGGCCGCTT
TGCTGGACTGGCCACAAGGCACGTTCGCATCGAAACTTGTCATCAAGGACGGACGTGCTGAAGTCACGCGTGAAATAGAC
GGAGGCCTTGAGATCATATCGCTGGCTTTGCCGGCTGTGGTGACCACCGATCTGCGTCTGAACGAGCCTCGCTACCTGAG
CCTGCCCAATATCATGAAGGCCAAGAAGAAGCCATTGGAGATCAGGCCTGTCGCCAGCTTCGATATCAATGTCGAGCCGC
GTTTGATCACTGTAAGGGTCGAAGAGCCAATGCAACGCCAGGCCGGTATCAAGGTGGCGGATGTTGCGACTCTTCTGAAC
AAGCTGAAGCATGAAGCAAAGGTAATCTGA

Upstream 100 bases:

>100_bases
TTACACAATGGTCTGATCTTGATGGGAGTTTCGCGGGTCAGTTGGCATAAGTGATCGTTGGGGCCGTCGCGGAACGCAGG
CAGGACAGGAGAGAACGTGA

Downstream 100 bases:

>100_bases
AATGCGGGCGCTGGTTTTAGCCGAACATGATGGCCACTCTCTACGGGGAGCTACGTTGAATGCGATCACAGCCGCTGCCA
GCCTCGGAGGCAAGGTCGAT

Product: electron transfer flavoprotein alpha/beta-subunit

Products: NA

Alternate protein names: Beta-ETF; Electron transfer flavoprotein small subunit; ETFSS [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKVLVPIKRVVDYNVKIRVKADHSGVETANVKYSANPFDEIAVEEAVRLKEAGIVSEIVVVSIGAAAAQDVLRNALALGA
DRAILVQTDHEIQPLAVAKLLKLLCLQESPQLVILGKQAIDDDSNQTGQALAALLDWPQGTFASKLVIKDGRAEVTREID
GGLEIISLALPAVVTTDLRLNEPRYLSLPNIMKAKKKPLEIRPVASFDINVEPRLITVRVEEPMQRQAGIKVADVATLLN
KLKHEAKVI

Sequences:

>Translated_249_residues
MKVLVPIKRVVDYNVKIRVKADHSGVETANVKYSANPFDEIAVEEAVRLKEAGIVSEIVVVSIGAAAAQDVLRNALALGA
DRAILVQTDHEIQPLAVAKLLKLLCLQESPQLVILGKQAIDDDSNQTGQALAALLDWPQGTFASKLVIKDGRAEVTREID
GGLEIISLALPAVVTTDLRLNEPRYLSLPNIMKAKKKPLEIRPVASFDINVEPRLITVRVEEPMQRQAGIKVADVATLLN
KLKHEAKVI
>Mature_249_residues
MKVLVPIKRVVDYNVKIRVKADHSGVETANVKYSANPFDEIAVEEAVRLKEAGIVSEIVVVSIGAAAAQDVLRNALALGA
DRAILVQTDHEIQPLAVAKLLKLLCLQESPQLVILGKQAIDDDSNQTGQALAALLDWPQGTFASKLVIKDGRAEVTREID
GGLEIISLALPAVVTTDLRLNEPRYLSLPNIMKAKKKPLEIRPVASFDINVEPRLITVRVEEPMQRQAGIKVADVATLLN
KLKHEAKVI

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=252, Percent_Identity=54.3650793650794, Blast_Score=264, Evalue=6e-71,
Organism=Homo sapiens, GI62420877, Length=237, Percent_Identity=53.5864978902954, Blast_Score=242, Evalue=2e-64,
Organism=Escherichia coli, GI87081682, Length=232, Percent_Identity=25.8620689655172, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25141345, Length=255, Percent_Identity=54.1176470588235, Blast_Score=249, Evalue=7e-67,
Organism=Saccharomyces cerevisiae, GI6321646, Length=251, Percent_Identity=51.792828685259, Blast_Score=250, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24651147, Length=251, Percent_Identity=54.9800796812749, Blast_Score=251, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24651145, Length=251, Percent_Identity=54.9800796812749, Blast_Score=251, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 27106; Mature: 27106

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS01065 ETF_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVPIKRVVDYNVKIRVKADHSGVETANVKYSANPFDEIAVEEAVRLKEAGIVSEIVV
CCEEEECHHHHCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHH
VSIGAAAAQDVLRNALALGADRAILVQTDHEIQPLAVAKLLKLLCLQESPQLVILGKQAI
HCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHC
DDDSNQTGQALAALLDWPQGTFASKLVIKDGRAEVTREIDGGLEIISLALPAVVTTDLRL
CCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHEEECEEE
NEPRYLSLPNIMKAKKKPLEIRPVASFDINVEPRLITVRVEEPMQRQAGIKVADVATLLN
CCCCEECCCHHHHHCCCCCEEEEEEEEECCCCCEEEEEEECCCHHHHHCCCHHHHHHHHH
KLKHEAKVI
HHHHHHCCC
>Mature Secondary Structure
MKVLVPIKRVVDYNVKIRVKADHSGVETANVKYSANPFDEIAVEEAVRLKEAGIVSEIVV
CCEEEECHHHHCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHH
VSIGAAAAQDVLRNALALGADRAILVQTDHEIQPLAVAKLLKLLCLQESPQLVILGKQAI
HCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHC
DDDSNQTGQALAALLDWPQGTFASKLVIKDGRAEVTREIDGGLEIISLALPAVVTTDLRL
CCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHEEECEEE
NEPRYLSLPNIMKAKKKPLEIRPVASFDINVEPRLITVRVEEPMQRQAGIKVADVATLLN
CCCCEECCCHHHHHCCCCCEEEEEEEEECCCCCEEEEEEECCCHHHHHCCCHHHHHHHHH
KLKHEAKVI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]