Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 182678724

GI number: 182678724

Start: 1982541

End: 1983476

Strand: Reverse

Name: etfA [H]

Synonym: Bind_1751

Alternate gene names: 182678724

Gene position: 1983476-1982541 (Counterclockwise)

Preceding gene: 182678725

Following gene: 182678723

Centisome position: 47.56

GC content: 55.66

Gene sequence:

>936_bases
ATGCGGGCGCTGGTTTTAGCCGAACATGATGGCCACTCTCTACGGGGAGCTACGTTGAATGCGATCACAGCCGCTGCCAG
CCTCGGAGGCAAGGTCGATCTTTTGGTCGCTGGCCATGATGTTCGTGCCATAGGCGAGGCAGGGACCACCATAGCCGGCG
TCGATAAGGTTCTGATCGCAGACGACCCGGTATATGCTCACCCGCTTGCCGAGACGGTCGCGGCCTTGCTAATAGAACAT
GCGCGAAACTATGAAGCGATCGTCGCTGCTGCCACGACATTTGGCAAAAATGTGCTGCCGCGTGTTGCCGCAACGCTCGA
TGTCCAGCAAATTTCGGAGGTCACGGGCGTGGTCTCTCCGGATACGTTCATTCGTCCTATTTATGCGGGCAATGCACTGG
CAACCGTGCGCTCACAGGATGCATTGAAAGTCATCACAATTCGCACGACAGCTTTTGAGCCTGCTGATGCCGAGACGGGT
AGGGCGACCATTTCCCAGATCCCTGCGGTCCATGCGCCCATCAATGTGCAGTTCATTCGAGAGGAACTGACGACATCGGA
GCGTCCGGATCTGACATCCGCACGGATTATCATTTCGGGCGGACGGGGCATGCAGAGTGGAGAAAATTTCAAGATGCTCG
AACCGATCGCTGAGAAGTTGGGTGCGGCCATCGGTGCCAGCAGAGCCGCTGTTGATGCCGGTTTTGTATCCAATGATCTC
CAGGTCGGCCAAACAGGCAAGATCGTCGCGCCGCAGCTTTATATCGCGGTTGGGATTTCCGGCGCCATTCAGCATCTTGC
AGGGATGAGTGGCTCGAAGGTGATTGTCGCCATCAATAAAGACGAAGACGCTCCCATTTTTCAGGTCGCCGATTATGGTC
TTGTTGGGGATCTGTTCAAGGTTTTACCCGAGTTGACCGCGTCACTTTCGGATTAG

Upstream 100 bases:

>100_bases
GTAAGGGTCGAAGAGCCAATGCAACGCCAGGCCGGTATCAAGGTGGCGGATGTTGCGACTCTTCTGAACAAGCTGAAGCA
TGAAGCAAAGGTAATCTGAA

Downstream 100 bases:

>100_bases
TAACTCCCGTTAGGTGATTTGGCAGGTAAATGTGGTCTGCTCCTCCCCGGGCCACAACAGGTGGGTCCTCTTCTCCCACG
GAGGACCCACCTTCTGCAAG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRALVLAEHDGHSLRGATLNAITAAASLGGKVDLLVAGHDVRAIGEAGTTIAGVDKVLIADDPVYAHPLAETVAALLIEH
ARNYEAIVAAATTFGKNVLPRVAATLDVQQISEVTGVVSPDTFIRPIYAGNALATVRSQDALKVITIRTTAFEPADAETG
RATISQIPAVHAPINVQFIREELTTSERPDLTSARIIISGGRGMQSGENFKMLEPIAEKLGAAIGASRAAVDAGFVSNDL
QVGQTGKIVAPQLYIAVGISGAIQHLAGMSGSKVIVAINKDEDAPIFQVADYGLVGDLFKVLPELTASLSD

Sequences:

>Translated_311_residues
MRALVLAEHDGHSLRGATLNAITAAASLGGKVDLLVAGHDVRAIGEAGTTIAGVDKVLIADDPVYAHPLAETVAALLIEH
ARNYEAIVAAATTFGKNVLPRVAATLDVQQISEVTGVVSPDTFIRPIYAGNALATVRSQDALKVITIRTTAFEPADAETG
RATISQIPAVHAPINVQFIREELTTSERPDLTSARIIISGGRGMQSGENFKMLEPIAEKLGAAIGASRAAVDAGFVSNDL
QVGQTGKIVAPQLYIAVGISGAIQHLAGMSGSKVIVAINKDEDAPIFQVADYGLVGDLFKVLPELTASLSD
>Mature_311_residues
MRALVLAEHDGHSLRGATLNAITAAASLGGKVDLLVAGHDVRAIGEAGTTIAGVDKVLIADDPVYAHPLAETVAALLIEH
ARNYEAIVAAATTFGKNVLPRVAATLDVQQISEVTGVVSPDTFIRPIYAGNALATVRSQDALKVITIRTTAFEPADAETG
RATISQIPAVHAPINVQFIREELTTSERPDLTSARIIISGGRGMQSGENFKMLEPIAEKLGAAIGASRAAVDAGFVSNDL
QVGQTGKIVAPQLYIAVGISGAIQHLAGMSGSKVIVAINKDEDAPIFQVADYGLVGDLFKVLPELTASLSD

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=55.8823529411765, Blast_Score=335, Evalue=3e-92,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=55.6363636363636, Blast_Score=304, Evalue=8e-83,
Organism=Escherichia coli, GI1787990, Length=252, Percent_Identity=34.5238095238095, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786226, Length=186, Percent_Identity=38.1720430107527, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87082157, Length=247, Percent_Identity=32.3886639676113, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=309, Percent_Identity=55.0161812297735, Blast_Score=329, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6325261, Length=271, Percent_Identity=49.4464944649446, Blast_Score=260, Evalue=2e-70,
Organism=Drosophila melanogaster, GI17136898, Length=309, Percent_Identity=56.6343042071197, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI24652801, Length=309, Percent_Identity=56.6343042071197, Blast_Score=337, Evalue=6e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32299; Mature: 32299

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALVLAEHDGHSLRGATLNAITAAASLGGKVDLLVAGHDVRAIGEAGTTIAGVDKVLIA
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCEEECCCEEEEE
DDPVYAHPLAETVAALLIEHARNYEAIVAAATTFGKNVLPRVAATLDVQQISEVTGVVSP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHCHHHHHHHHCCCCC
DTFIRPIYAGNALATVRSQDALKVITIRTTAFEPADAETGRATISQIPAVHAPINVQFIR
CHHCCEEECCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCHHHHHCCEECCCCCHHHHH
EELTTSERPDLTSARIIISGGRGMQSGENFKMLEPIAEKLGAAIGASRAAVDAGFVSNDL
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMSGSKVIVAINKDEDAPIFQVADYGLVGDLFK
EECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHH
VLPELTASLSD
HHHHHHHHCCC
>Mature Secondary Structure
MRALVLAEHDGHSLRGATLNAITAAASLGGKVDLLVAGHDVRAIGEAGTTIAGVDKVLIA
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCEEECCCEEEEE
DDPVYAHPLAETVAALLIEHARNYEAIVAAATTFGKNVLPRVAATLDVQQISEVTGVVSP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHHHHHHHCHHHHHHHHCCCCC
DTFIRPIYAGNALATVRSQDALKVITIRTTAFEPADAETGRATISQIPAVHAPINVQFIR
CHHCCEEECCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCHHHHHCCEECCCCCHHHHH
EELTTSERPDLTSARIIISGGRGMQSGENFKMLEPIAEKLGAAIGASRAAVDAGFVSNDL
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMSGSKVIVAINKDEDAPIFQVADYGLVGDLFK
EECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCHHHHHHH
VLPELTASLSD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]