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The map label for this gene is ntrY [H]

Identifier: 182678496

GI number: 182678496

Start: 1720870

End: 1723143

Strand: Direct

Name: ntrY [H]

Synonym: Bind_1520

Alternate gene names: 182678496

Gene position: 1720870-1723143 (Clockwise)

Preceding gene: 182678495

Following gene: 182678497

Centisome position: 41.27

GC content: 59.41

Gene sequence:

>2274_bases
ATGCCTGATCTCGACGTAACGCATCATGCTCCAGCCTCCGGCGCTTCCAAACTCGAGCGCCGCTGGACGACCCCGCTTGG
CGCCTCCTTCGTCCTTCTGGCGCTGGTGACCGCGCTCAGCAGCTTTCTGATCTTCGCCGGCTATACGCCGATCCCGGTGA
ATGACACGATCGTCCTCAGCCTGTTCGTCGCCAATATCGCCAGCATTCTCCTTCTCTTCGGCCTCGTTCTCGTTGAAGCC
TACAGGCTTTATGCCGCCTGGCGCAGCAAGGTCGCGGGCGCGCGGCTGCATTTGCGGATCGTCGCTCTATTCTCGATCGT
CGCGGCGGCGCCGGCCTTGCTCATGGCCTGGGTCGGTTCGGTTACCCTGGAACGCAGTCTCAACCCGTCCTTCATGCAGG
ATGTGCGAGGCTTCGTGCTCAATACGATCGATGCGGCGCGGCTGTTCCGCGAGGGTCAGTGCAAGGCCTTGCTGCAAGAA
GCTTCCTTGACCGCGGCCGATCTCGATCGCGCCAAAACCGTGATGTTCGAGGGACACCGCGAATTGTTTCGCGATTTCTT
TGCCTCGCGGGCGAAATTCCTGGGCTTTACCGCCGCGGCGCTCATGAAATCCGATGGCCAGATCGTGGAGAGGATCGATA
CTCATGCGGCTATGGGCACGGCGGTGGTGCAGCCGGAACCAAGCGACTTCGAGGATGCTCGCAAGAACGAGCCTTTGTGC
CTGATCCTCGACGAGGGTGGGACCTTTGTCGCCTTACGGCCGGTTTCGGGATTTCCTGATACATTTCTCTATGTCGCTCG
GCCGGTCGATCGTTTCACCGTCGCCTTCCCGCGCGAGGCTTCCAAGCTCGTTGCGATTTATGATGCCTTCGACAGCCACC
GGCGCGGCATTCAGATCGCCTTTGCCGCCATGTTCGTCTCGATCGCGCTGATCATGGTTCTAGCGGCAACCTGGCTCGGC
CTTTCTTTCGCCAATCAGCTCGTCGCACCGATCCGCCGACTGATCGCCGCGACCGACCAGGTCGCTTCCGGCAATCTGTC
CGTTCAGGTCGCGGTCTATCGTGACGAGGGGGATCTCGCCCGGCTTGGCGAGACCTTCAACAAGATGATCGCGGAATTGC
GTCTGCAGCAAAATCGATTGATCGCCGCCAGCAATCTGATCGATGAAAGGCGTTTGTTTACCGAGGCGGTGCTGTCCGGC
GTGCCGGTCGCCGTGGTTGGCATCGGTCCAAAGGGCCTGGTTACGGTGCTGAATGCCTCGGCCGAAAAACTCGTGCCCAT
GGGCGCGGAGGAATTGACCACCGTGACAGGCCAGCCGGTTGAGGCTGTGCTGCCGGAAATCGCGGATCTGTTCAATGAGG
CGCGGGCCAGTACGATGCGGCTGATGCAGGGTCAGATCAGCCTTGATCGTGGCGGCCGTGATCGGCTTTTCAATGTCAGC
ATCACATCCGAGCCGACCGCGCGGACCGATAAAAGCTATGTTGTGACGCTCGACGATATTACCGATCTCGTGACGGCCCA
GCGCACTGCCGCCTGGGCGGATGTCGCCCGCAGAATTGCTCACGAAATCAAAAATCCCCTGACACCGATCCAGCTTTCGG
CGGAACGCCTGAAACGCAAATATGGACGCGTGATTGTCCAGGATCGCGATATTTTCGATCAATGCATCGATACGATCGTG
CGGCAGGTCGATGACATCAAACGCATGGTCGATGAATTTTCTTCCTTCGCACGGATGCCCAAGGCCAAACTTGATTCCGA
TGATCTGACTGATTGCCTGCGCCGCGTCCTGTTTCTCATGCGCGTGGCGCATCCGGACATCACCTTCGATGAGGATTTGC
CGGAGAAATCCGTCATCGGCCGCTTCGACAGGCGGCTTTTGTCCCAGGCCGTGACCAATATTCTTAAAAACGCTGCCGAA
GGCATAGCAGCCGTAGCGGAAACAGAGCAGGGTAACCGGGCGCCGGGCCGCATCCTCCTCAGGCTTCTCGTGCGCGGTGA
TCAAGCGGAAATCGATATTATCGATAATGGCAAGGGTTTCCCGCGCGAAAACCGGCACCGTCTGCTCGAGCCCTATATGA
CGACTCGCGCCGAGGGGACAGGACTTGGCCTGCCGATTGTCGCCAAGATTCTGGAGGATCACGGCGGATCTCTCGAACTC
CTGGATGCGCCTGATGGACAGGGCGCCTTCGTCAAACTGCTTCTGCCACTTGGCGGAGCTCAGGAAAAGGAACCACGCGC
GCCGGTTGCGCTTCTCTCGATGAACGAGGAATGA

Upstream 100 bases:

>100_bases
TCCGAGCCTTGGCCCCGCCTCGACACCGGGGCCAAGACTTTTTCATTTCCTGCGCGTTCATTCCTTGTGCGACTATACGG
CTTTGAAACCTAAGGGCCTG

Downstream 100 bases:

>100_bases
GACACCAATGGTCACGCTTGCGGCACGCCGTTTTTTTCGTTTCTGTCTGTCTGACGAATCTCCTTTTCGCCAGTGGTCGA
TAGGAAAGCGCATAGCGTGC

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 756

Protein sequence:

>757_residues
MPDLDVTHHAPASGASKLERRWTTPLGASFVLLALVTALSSFLIFAGYTPIPVNDTIVLSLFVANIASILLLFGLVLVEA
YRLYAAWRSKVAGARLHLRIVALFSIVAAAPALLMAWVGSVTLERSLNPSFMQDVRGFVLNTIDAARLFREGQCKALLQE
ASLTAADLDRAKTVMFEGHRELFRDFFASRAKFLGFTAAALMKSDGQIVERIDTHAAMGTAVVQPEPSDFEDARKNEPLC
LILDEGGTFVALRPVSGFPDTFLYVARPVDRFTVAFPREASKLVAIYDAFDSHRRGIQIAFAAMFVSIALIMVLAATWLG
LSFANQLVAPIRRLIAATDQVASGNLSVQVAVYRDEGDLARLGETFNKMIAELRLQQNRLIAASNLIDERRLFTEAVLSG
VPVAVVGIGPKGLVTVLNASAEKLVPMGAEELTTVTGQPVEAVLPEIADLFNEARASTMRLMQGQISLDRGGRDRLFNVS
ITSEPTARTDKSYVVTLDDITDLVTAQRTAAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRVIVQDRDIFDQCIDTIV
RQVDDIKRMVDEFSSFARMPKAKLDSDDLTDCLRRVLFLMRVAHPDITFDEDLPEKSVIGRFDRRLLSQAVTNILKNAAE
GIAAVAETEQGNRAPGRILLRLLVRGDQAEIDIIDNGKGFPRENRHRLLEPYMTTRAEGTGLGLPIVAKILEDHGGSLEL
LDAPDGQGAFVKLLLPLGGAQEKEPRAPVALLSMNEE

Sequences:

>Translated_757_residues
MPDLDVTHHAPASGASKLERRWTTPLGASFVLLALVTALSSFLIFAGYTPIPVNDTIVLSLFVANIASILLLFGLVLVEA
YRLYAAWRSKVAGARLHLRIVALFSIVAAAPALLMAWVGSVTLERSLNPSFMQDVRGFVLNTIDAARLFREGQCKALLQE
ASLTAADLDRAKTVMFEGHRELFRDFFASRAKFLGFTAAALMKSDGQIVERIDTHAAMGTAVVQPEPSDFEDARKNEPLC
LILDEGGTFVALRPVSGFPDTFLYVARPVDRFTVAFPREASKLVAIYDAFDSHRRGIQIAFAAMFVSIALIMVLAATWLG
LSFANQLVAPIRRLIAATDQVASGNLSVQVAVYRDEGDLARLGETFNKMIAELRLQQNRLIAASNLIDERRLFTEAVLSG
VPVAVVGIGPKGLVTVLNASAEKLVPMGAEELTTVTGQPVEAVLPEIADLFNEARASTMRLMQGQISLDRGGRDRLFNVS
ITSEPTARTDKSYVVTLDDITDLVTAQRTAAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRVIVQDRDIFDQCIDTIV
RQVDDIKRMVDEFSSFARMPKAKLDSDDLTDCLRRVLFLMRVAHPDITFDEDLPEKSVIGRFDRRLLSQAVTNILKNAAE
GIAAVAETEQGNRAPGRILLRLLVRGDQAEIDIIDNGKGFPRENRHRLLEPYMTTRAEGTGLGLPIVAKILEDHGGSLEL
LDAPDGQGAFVKLLLPLGGAQEKEPRAPVALLSMNEE
>Mature_756_residues
PDLDVTHHAPASGASKLERRWTTPLGASFVLLALVTALSSFLIFAGYTPIPVNDTIVLSLFVANIASILLLFGLVLVEAY
RLYAAWRSKVAGARLHLRIVALFSIVAAAPALLMAWVGSVTLERSLNPSFMQDVRGFVLNTIDAARLFREGQCKALLQEA
SLTAADLDRAKTVMFEGHRELFRDFFASRAKFLGFTAAALMKSDGQIVERIDTHAAMGTAVVQPEPSDFEDARKNEPLCL
ILDEGGTFVALRPVSGFPDTFLYVARPVDRFTVAFPREASKLVAIYDAFDSHRRGIQIAFAAMFVSIALIMVLAATWLGL
SFANQLVAPIRRLIAATDQVASGNLSVQVAVYRDEGDLARLGETFNKMIAELRLQQNRLIAASNLIDERRLFTEAVLSGV
PVAVVGIGPKGLVTVLNASAEKLVPMGAEELTTVTGQPVEAVLPEIADLFNEARASTMRLMQGQISLDRGGRDRLFNVSI
TSEPTARTDKSYVVTLDDITDLVTAQRTAAWADVARRIAHEIKNPLTPIQLSAERLKRKYGRVIVQDRDIFDQCIDTIVR
QVDDIKRMVDEFSSFARMPKAKLDSDDLTDCLRRVLFLMRVAHPDITFDEDLPEKSVIGRFDRRLLSQAVTNILKNAAEG
IAAVAETEQGNRAPGRILLRLLVRGDQAEIDIIDNGKGFPRENRHRLLEPYMTTRAEGTGLGLPIVAKILEDHGGSLELL
DAPDGQGAFVKLLLPLGGAQEKEPRAPVALLSMNEE

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=399, Percent_Identity=24.812030075188, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=27.8481012658228, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790300, Length=332, Percent_Identity=25, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82986; Mature: 82855

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLDVTHHAPASGASKLERRWTTPLGASFVLLALVTALSSFLIFAGYTPIPVNDTIVLS
CCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LFVANIASILLLFGLVLVEAYRLYAAWRSKVAGARLHLRIVALFSIVAAAPALLMAWVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTLERSLNPSFMQDVRGFVLNTIDAARLFREGQCKALLQEASLTAADLDRAKTVMFEGHR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ELFRDFFASRAKFLGFTAAALMKSDGQIVERIDTHAAMGTAVVQPEPSDFEDARKNEPLC
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEECCCCCCHHHHHCCCCEE
LILDEGGTFVALRPVSGFPDTFLYVARPVDRFTVAFPREASKLVAIYDAFDSHRRGIQIA
EEEECCCCEEEEECCCCCCHHHHHHHCCHHHHEEECCCCCCHHEEHHHHHHHHCCCHHHH
FAAMFVSIALIMVLAATWLGLSFANQLVAPIRRLIAATDQVASGNLSVQVAVYRDEGDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH
RLGETFNKMIAELRLQQNRLIAASNLIDERRLFTEAVLSGVPVAVVGIGPKGLVTVLNAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCC
AEKLVPMGAEELTTVTGQPVEAVLPEIADLFNEARASTMRLMQGQISLDRGGRDRLFNVS
HHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEE
ITSEPTARTDKSYVVTLDDITDLVTAQRTAAWADVARRIAHEIKNPLTPIQLSAERLKRK
ECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YGRVIVQDRDIFDQCIDTIVRQVDDIKRMVDEFSSFARMPKAKLDSDDLTDCLRRVLFLM
HCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RVAHPDITFDEDLPEKSVIGRFDRRLLSQAVTNILKNAAEGIAAVAETEQGNRAPGRILL
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RLLVRGDQAEIDIIDNGKGFPRENRHRLLEPYMTTRAEGTGLGLPIVAKILEDHGGSLEL
HHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEE
LDAPDGQGAFVKLLLPLGGAQEKEPRAPVALLSMNEE
EECCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCC
>Mature Secondary Structure 
PDLDVTHHAPASGASKLERRWTTPLGASFVLLALVTALSSFLIFAGYTPIPVNDTIVLS
CCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
LFVANIASILLLFGLVLVEAYRLYAAWRSKVAGARLHLRIVALFSIVAAAPALLMAWVGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTLERSLNPSFMQDVRGFVLNTIDAARLFREGQCKALLQEASLTAADLDRAKTVMFEGHR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ELFRDFFASRAKFLGFTAAALMKSDGQIVERIDTHAAMGTAVVQPEPSDFEDARKNEPLC
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEECCCCCCHHHHHCCCCEE
LILDEGGTFVALRPVSGFPDTFLYVARPVDRFTVAFPREASKLVAIYDAFDSHRRGIQIA
EEEECCCCEEEEECCCCCCHHHHHHHCCHHHHEEECCCCCCHHEEHHHHHHHHCCCHHHH
FAAMFVSIALIMVLAATWLGLSFANQLVAPIRRLIAATDQVASGNLSVQVAVYRDEGDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHH
RLGETFNKMIAELRLQQNRLIAASNLIDERRLFTEAVLSGVPVAVVGIGPKGLVTVLNAS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCC
AEKLVPMGAEELTTVTGQPVEAVLPEIADLFNEARASTMRLMQGQISLDRGGRDRLFNVS
HHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEE
ITSEPTARTDKSYVVTLDDITDLVTAQRTAAWADVARRIAHEIKNPLTPIQLSAERLKRK
ECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YGRVIVQDRDIFDQCIDTIVRQVDDIKRMVDEFSSFARMPKAKLDSDDLTDCLRRVLFLM
HCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
RVAHPDITFDEDLPEKSVIGRFDRRLLSQAVTNILKNAAEGIAAVAETEQGNRAPGRILL
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RLLVRGDQAEIDIIDNGKGFPRENRHRLLEPYMTTRAEGTGLGLPIVAKILEDHGGSLEL
HHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEE
LDAPDGQGAFVKLLLPLGGAQEKEPRAPVALLSMNEE
EECCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]