Click here to switch to the map view.

The map label for this gene is fsr [C]

Identifier: 182678410

GI number: 182678410

Start: 1638382

End: 1639719

Strand: Direct

Name: fsr [C]

Synonym: Bind_1427

Alternate gene names: 182678410

Gene position: 1638382-1639719 (Clockwise)

Preceding gene: 182678409

Following gene: 182678412

Centisome position: 39.29

GC content: 56.05

Gene sequence:

>1338_bases
ATGAGCATTTACTCATGGATGGATGAGTATCCTTTAGTTGCTGAGAAAGTCGCCTTCTCTTTAAAGTTGGGGGGTGGGAA
GGCAGCCATCCGGATTGAATGGCTGCCTGCAATTCAACGGAGCGCGGGCGATAAGATGCTCAACGTGGATATGGCGCAGA
ATGTTGATGGAGCATCGAAAATGAAAGCCGCGAAGCAACGGCGCGATCTCGTCGGAGCCTGCCTTGCCCATACGCTGCAT
GATGGCTACACTGACCAACTCTACGCGCTGCTGCCGATCTGGCAGACAGAATTTGGGCTTTCCTATGCGGGCCTCGCGAT
AATCCGAGTGCTCTATTATGGTACGATGGGCTGTCTTCAGGTGCCTGGTGACAAGGTACTTGGACGAGTTACTGCACGCT
GGGCATTAGCATTGGCGACATTCGTGGCAGCTCTGGGATATCTGGTGATGGCTTTACCGGGCGGTCTGTTCGTTTTGAGT
GCGGGACTGATCGTTGCAGGCGTCGGATCGAGCACTCAGCATCCTCGCGCCTCCCTTCTCGTGACCAACGCCTATGGGAA
GGAATCACGAGGCCCGTTGGGAGTTTATAATTTCTCCGGTGACTTGGGCAAAGCCGTCCTGCCGGCACTTGTCGCGTTAC
TGCTCCCATTCTTGGCTTGGCGCGCAGTGATCACGCTGACAGCACTCCTGGGCTTCTTGGTCGCCGGAGTGTTGCTGGTG
CTCATTCCGCGCCAACGCACACTTCCGACCTTGCTCGACGAGAGACACATTGGGAATACGGCGAGCGGTAAAGGTTTTGG
TTTACTCCTCGCGATCGGCGCACTCGATACCGCGCCACGGATGGGTTATCTGCTGTTTCTGCCGTTTCTCATTCACGCCA
AAGGCGGAACACAAGCGATGGTTGGCGTCGGCTTGGCGCTGCTTTTTATCGGCGGCGCGCTGGGTAAAGCTGTCTGCGGC
TGGTTAGGACAGCGTCTCGGCGTCGTCTCGAGCGTGGTTATGACCGAGGCAGCCACTGCGTTGCTGATGATCGCAACTTT
GTTTTTCCCACTGGCTGTGACGCTTGCCTTGTTACCCTTGCTTGGCGTCGTCTTGAACGGCACTTCTTCCATCCTCTATG
GGACCGTTCCGGATTTGGCCCCGAAAGGTGATACCGGACGGGCGTTCGCGCTATTTTATACGGGTGTCATCGTCATGGGA
GGTTTCGCGCCAATCGCTTACGGCATGATTGCCGATCACACCAGTAGGGCCGTCGGTATATCGGCTTCGGCGTTGACGGC
GACCATAATCATTCCACTTGTTCTTGCGTTACGCCCGGCACTGATCAGACCCACATAA

Upstream 100 bases:

>100_bases
CGAAGGGGCGGGAGCGGCTACCCGCGATCGCATCGTTCAAGGAATGGATTGTTCAGGAGGCTCAGCAAGCACAGTCTACC
TACGACAGCGAGCAAGAGAT

Downstream 100 bases:

>100_bases
CCCAAGATTGCCGCGCTGAGCACGCCTAGCTAAAGAAGCCGGCGAAATGCCTGACAATGTTAAGAGAGCTATGGCGTGCC
TTAGGTAGCTATGGCGTAGG

Product: major facilitator transporter

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Facilitator Superfamily Protein; Transmembrane Efflux Protein; Transporter-Like Membrane Protein; Facilitator Family Protein

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MSIYSWMDEYPLVAEKVAFSLKLGGGKAAIRIEWLPAIQRSAGDKMLNVDMAQNVDGASKMKAAKQRRDLVGACLAHTLH
DGYTDQLYALLPIWQTEFGLSYAGLAIIRVLYYGTMGCLQVPGDKVLGRVTARWALALATFVAALGYLVMALPGGLFVLS
AGLIVAGVGSSTQHPRASLLVTNAYGKESRGPLGVYNFSGDLGKAVLPALVALLLPFLAWRAVITLTALLGFLVAGVLLV
LIPRQRTLPTLLDERHIGNTASGKGFGLLLAIGALDTAPRMGYLLFLPFLIHAKGGTQAMVGVGLALLFIGGALGKAVCG
WLGQRLGVVSSVVMTEAATALLMIATLFFPLAVTLALLPLLGVVLNGTSSILYGTVPDLAPKGDTGRAFALFYTGVIVMG
GFAPIAYGMIADHTSRAVGISASALTATIIIPLVLALRPALIRPT

Sequences:

>Translated_445_residues
MSIYSWMDEYPLVAEKVAFSLKLGGGKAAIRIEWLPAIQRSAGDKMLNVDMAQNVDGASKMKAAKQRRDLVGACLAHTLH
DGYTDQLYALLPIWQTEFGLSYAGLAIIRVLYYGTMGCLQVPGDKVLGRVTARWALALATFVAALGYLVMALPGGLFVLS
AGLIVAGVGSSTQHPRASLLVTNAYGKESRGPLGVYNFSGDLGKAVLPALVALLLPFLAWRAVITLTALLGFLVAGVLLV
LIPRQRTLPTLLDERHIGNTASGKGFGLLLAIGALDTAPRMGYLLFLPFLIHAKGGTQAMVGVGLALLFIGGALGKAVCG
WLGQRLGVVSSVVMTEAATALLMIATLFFPLAVTLALLPLLGVVLNGTSSILYGTVPDLAPKGDTGRAFALFYTGVIVMG
GFAPIAYGMIADHTSRAVGISASALTATIIIPLVLALRPALIRPT
>Mature_444_residues
SIYSWMDEYPLVAEKVAFSLKLGGGKAAIRIEWLPAIQRSAGDKMLNVDMAQNVDGASKMKAAKQRRDLVGACLAHTLHD
GYTDQLYALLPIWQTEFGLSYAGLAIIRVLYYGTMGCLQVPGDKVLGRVTARWALALATFVAALGYLVMALPGGLFVLSA
GLIVAGVGSSTQHPRASLLVTNAYGKESRGPLGVYNFSGDLGKAVLPALVALLLPFLAWRAVITLTALLGFLVAGVLLVL
IPRQRTLPTLLDERHIGNTASGKGFGLLLAIGALDTAPRMGYLLFLPFLIHAKGGTQAMVGVGLALLFIGGALGKAVCGW
LGQRLGVVSSVVMTEAATALLMIATLFFPLAVTLALLPLLGVVLNGTSSILYGTVPDLAPKGDTGRAFALFYTGVIVMGG
FAPIAYGMIADHTSRAVGISASALTATIIIPLVLALRPALIRPT

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46582; Mature: 46451

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYSWMDEYPLVAEKVAFSLKLGGGKAAIRIEWLPAIQRSAGDKMLNVDMAQNVDGASK
CCHHHHHHCCCHHHHHHHEEEEECCCCEEEEEEECHHHHHCCCCCEEEEHHHCCCCCHHH
MKAAKQRRDLVGACLAHTLHDGYTDQLYALLPIWQTEFGLSYAGLAIIRVLYYGTMGCLQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEE
VPGDKVLGRVTARWALALATFVAALGYLVMALPGGLFVLSAGLIVAGVGSSTQHPRASLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCEEEE
VTNAYGKESRGPLGVYNFSGDLGKAVLPALVALLLPFLAWRAVITLTALLGFLVAGVLLV
EEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIPRQRTLPTLLDERHIGNTASGKGFGLLLAIGALDTAPRMGYLLFLPFLIHAKGGTQAM
HCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHH
VGVGLALLFIGGALGKAVCGWLGQRLGVVSSVVMTEAATALLMIATLFFPLAVTLALLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVVLNGTSSILYGTVPDLAPKGDTGRAFALFYTGVIVMGGFAPIAYGMIADHTSRAVGI
HHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
SASALTATIIIPLVLALRPALIRPT
CHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
SIYSWMDEYPLVAEKVAFSLKLGGGKAAIRIEWLPAIQRSAGDKMLNVDMAQNVDGASK
CHHHHHHCCCHHHHHHHEEEEECCCCEEEEEEECHHHHHCCCCCEEEEHHHCCCCCHHH
MKAAKQRRDLVGACLAHTLHDGYTDQLYALLPIWQTEFGLSYAGLAIIRVLYYGTMGCLQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEE
VPGDKVLGRVTARWALALATFVAALGYLVMALPGGLFVLSAGLIVAGVGSSTQHPRASLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCEEEE
VTNAYGKESRGPLGVYNFSGDLGKAVLPALVALLLPFLAWRAVITLTALLGFLVAGVLLV
EEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIPRQRTLPTLLDERHIGNTASGKGFGLLLAIGALDTAPRMGYLLFLPFLIHAKGGTQAM
HCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHH
VGVGLALLFIGGALGKAVCGWLGQRLGVVSSVVMTEAATALLMIATLFFPLAVTLALLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVVLNGTSSILYGTVPDLAPKGDTGRAFALFYTGVIVMGGFAPIAYGMIADHTSRAVGI
HHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
SASALTATIIIPLVLALRPALIRPT
CHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA