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The map label for this gene is ribD [H]

Identifier: 182678211

GI number: 182678211

Start: 1423365

End: 1424570

Strand: Direct

Name: ribD [H]

Synonym: Bind_1226

Alternate gene names: 182678211

Gene position: 1423365-1424570 (Clockwise)

Preceding gene: 182678210

Following gene: 182678212

Centisome position: 34.13

GC content: 64.01

Gene sequence:

>1206_bases
ATGTTTCACCCGCCCATGCTTTCGCGCGGCTCTGGCATGCAGCCGATCGTCTCTCCCGACAGTGAGACCGATACGCATTA
TATGGCCGAGGCCTTGGCGTTGAGCCAGCAAGGTCTCGGCCGTACAGCGCCCAATCCTTCGGTCGGGGCAATCATCGTCA
AGGACGGAAAGATCGTCGGACGCGGTTGGACTCAGCCGGGAGGGCGGCCGCATGCCGAGACCGAGGCTTTGGCCGAGGCA
GGGGATGCGGCGCGTGGCGCGACGCTCTATGTCACTTTGGAACCGTGCAGCCATTTTGGTGTCACGCCGCCTTGTGCCTC
GGCGATCATCGCGGCGGGCGTCGCCCGCGTGGTCTGCGCGCTGGAAGATCCAGATCCCCGAGTGTCGGGGCGGGGCTATC
GCATGTTGCGGGAAGCCGGCATTGCCGTGACTCATGGCGTGCTGGAAGCCGAAGCACGCCGCGCCAATCTCGGCCATATC
CGGCGCGTGCAGGCTCAGCGCCCGATGGTGACCTTGAAACTCGCCATGACCGCTGACGGCTTCGTGGCCAGCACGGCGCC
ACGAGAAGGGCAGGCACCCCGGCTCAAAATCACCGGCGCGGCCGCCAATGAGCACGTCCATCGGATGCGTGCCCAGCATG
ATGCCATCATGATCGGCATCGGCACGGCGCTAGCCGATGATCCCATGCTGACGGTGCGGCTGTCAGGCCAGGAGGAGATG
GGTAAAGCGGAGATGGGTAAAGTGGCGGCCAGGCCGCGGCGCATCGTGCTCGACAGCCATTTACGCCTGCCGCTCCAATC
CCATCTCGTGCAGACTGCGGCCGATTATCCAACCCTTGTGCTGACGCGTGACGATGCCTCCGCCGAGGCCATGGCCCGGC
TGCGCGAGGCCTCCGTCGTGGTCGAAACGCTTGAAAGCGCGCAAAGCACGCCATCGCTTGATCTTTCCGCTGCCTTGCAG
CGTCTCGCCTCTCTCGGCCTGACACGGATTTTCTCTGAAGGGGGACCGCGTGTCGCGGAATCCTTGATTGGTCAGCATGC
CGCCGATGAGGTGATCCTGCTCGAATCGCCGGCGATTCTGGGTGCTGGCGTGGAGGGCCTTTCTCCCCGGGCGCGCGCCA
TTCTGGGTAACCTTACCCTTTATCGTCCTGCCGAGACACGGATGATCGAAGAGGACCGCCTCACCCGCTATGAAAGGATT
GATTGA

Upstream 100 bases:

>100_bases
CGTTGGACCACTCTTGAATTTTCGCCATCGCTTTGAAAAAGCGAAAATTCAAGAAAGGAACCAAAGGTCGTTCTTCACGA
CCTTTGGTATTAGAGGAAGG

Downstream 100 bases:

>100_bases
TCATGTTCACGGGGCTCATCAGCGATGTCGGTGAGGTTGGCGCGGTCGAGGAACGCGGACAATTGCGGCGCCTGCGGATT
TTCTGCTCCTATCCGGCGGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MFHPPMLSRGSGMQPIVSPDSETDTHYMAEALALSQQGLGRTAPNPSVGAIIVKDGKIVGRGWTQPGGRPHAETEALAEA
GDAARGATLYVTLEPCSHFGVTPPCASAIIAAGVARVVCALEDPDPRVSGRGYRMLREAGIAVTHGVLEAEARRANLGHI
RRVQAQRPMVTLKLAMTADGFVASTAPREGQAPRLKITGAAANEHVHRMRAQHDAIMIGIGTALADDPMLTVRLSGQEEM
GKAEMGKVAARPRRIVLDSHLRLPLQSHLVQTAADYPTLVLTRDDASAEAMARLREASVVVETLESAQSTPSLDLSAALQ
RLASLGLTRIFSEGGPRVAESLIGQHAADEVILLESPAILGAGVEGLSPRARAILGNLTLYRPAETRMIEEDRLTRYERI
D

Sequences:

>Translated_401_residues
MFHPPMLSRGSGMQPIVSPDSETDTHYMAEALALSQQGLGRTAPNPSVGAIIVKDGKIVGRGWTQPGGRPHAETEALAEA
GDAARGATLYVTLEPCSHFGVTPPCASAIIAAGVARVVCALEDPDPRVSGRGYRMLREAGIAVTHGVLEAEARRANLGHI
RRVQAQRPMVTLKLAMTADGFVASTAPREGQAPRLKITGAAANEHVHRMRAQHDAIMIGIGTALADDPMLTVRLSGQEEM
GKAEMGKVAARPRRIVLDSHLRLPLQSHLVQTAADYPTLVLTRDDASAEAMARLREASVVVETLESAQSTPSLDLSAALQ
RLASLGLTRIFSEGGPRVAESLIGQHAADEVILLESPAILGAGVEGLSPRARAILGNLTLYRPAETRMIEEDRLTRYERI
D
>Mature_401_residues
MFHPPMLSRGSGMQPIVSPDSETDTHYMAEALALSQQGLGRTAPNPSVGAIIVKDGKIVGRGWTQPGGRPHAETEALAEA
GDAARGATLYVTLEPCSHFGVTPPCASAIIAAGVARVVCALEDPDPRVSGRGYRMLREAGIAVTHGVLEAEARRANLGHI
RRVQAQRPMVTLKLAMTADGFVASTAPREGQAPRLKITGAAANEHVHRMRAQHDAIMIGIGTALADDPMLTVRLSGQEEM
GKAEMGKVAARPRRIVLDSHLRLPLQSHLVQTAADYPTLVLTRDDASAEAMARLREASVVVETLESAQSTPSLDLSAALQ
RLASLGLTRIFSEGGPRVAESLIGQHAADEVILLESPAILGAGVEGLSPRARAILGNLTLYRPAETRMIEEDRLTRYERI
D

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=346, Percent_Identity=42.7745664739884, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI145693172, Length=161, Percent_Identity=32.2981366459627, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 42692; Mature: 42692

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHPPMLSRGSGMQPIVSPDSETDTHYMAEALALSQQGLGRTAPNPSVGAIIVKDGKIVG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEE
RGWTQPGGRPHAETEALAEAGDAARGATLYVTLEPCSHFGVTPPCASAIIAAGVARVVCA
CCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEE
LEDPDPRVSGRGYRMLREAGIAVTHGVLEAEARRANLGHIRRVQAQRPMVTLKLAMTADG
ECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEEECCC
FVASTAPREGQAPRLKITGAAANEHVHRMRAQHDAIMIGIGTALADDPMLTVRLSGQEEM
CEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECHHHCCCCEEEEEECCHHHC
GKAEMGKVAARPRRIVLDSHLRLPLQSHLVQTAADYPTLVLTRDDASAEAMARLREASVV
CHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
VETLESAQSTPSLDLSAALQRLASLGLTRIFSEGGPRVAESLIGQHAADEVILLESPAIL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCEE
GAGVEGLSPRARAILGNLTLYRPAETRMIEEDRLTRYERID
ECCCCCCCHHHHHHHCCCEEECCHHHHEECHHHHHHHHCCC
>Mature Secondary Structure
MFHPPMLSRGSGMQPIVSPDSETDTHYMAEALALSQQGLGRTAPNPSVGAIIVKDGKIVG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEE
RGWTQPGGRPHAETEALAEAGDAARGATLYVTLEPCSHFGVTPPCASAIIAAGVARVVCA
CCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEE
LEDPDPRVSGRGYRMLREAGIAVTHGVLEAEARRANLGHIRRVQAQRPMVTLKLAMTADG
ECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEEECCC
FVASTAPREGQAPRLKITGAAANEHVHRMRAQHDAIMIGIGTALADDPMLTVRLSGQEEM
CEECCCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECHHHCCCCEEEEEECCHHHC
GKAEMGKVAARPRRIVLDSHLRLPLQSHLVQTAADYPTLVLTRDDASAEAMARLREASVV
CHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHH
VETLESAQSTPSLDLSAALQRLASLGLTRIFSEGGPRVAESLIGQHAADEVILLESPAIL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCEE
GAGVEGLSPRARAILGNLTLYRPAETRMIEEDRLTRYERID
ECCCCCCCHHHHHHHCCCEEECCHHHHEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]