| Definition | Beijerinckia indica subsp. indica ATCC 9039 chromosome, complete genome. |
|---|---|
| Accession | NC_010581 |
| Length | 4,170,153 |
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The map label for this gene is fabG [C]
Identifier: 182678207
GI number: 182678207
Start: 1419030
End: 1419806
Strand: Direct
Name: fabG [C]
Synonym: Bind_1222
Alternate gene names: 182678207
Gene position: 1419030-1419806 (Clockwise)
Preceding gene: 182678206
Following gene: 182678210
Centisome position: 34.03
GC content: 60.1
Gene sequence:
>777_bases ATGGCGGTCTATCGTGCGAGACCGAGAGATGGTGTGGCCTGGGTCACGGGGGCCAGTTCCGGCATCGGGCGGGCTGTGGC CATGGAACTGGCGCGGCGAGGCTACAGGGTCGCTGCCACGGCGCGGCGCAAGGGTGATCTCGAGGATCTTGCCGCCGCCA TGCCGAATATCATCAGCTTTCCGGGCGATGTGACCGATCTCGCTGGCATGCGGGCGATGGTCAAACGCATTGAGCGTCAG CTTGGGCCTATCGCGCTCGCCTTTTTCAATGCTGGCGTCTATTTCATTCAGGAGCGCAAGGGGCTGGCGGCGGAAATCGC GTGGCGGACTTTCGAGGTCAATACGGGCGGCGTCCTGAATTGCCTCGATCCTTTGCTGCCGGAAATGCGTCGAAGACGCT TTGGGCAGATCGTTCTGAATGCCTCGCTTGCAGGTTATGGCGGCATTCCGGGTTCGCTCGCCTATGGCGCGAGCAAGGCG GCTTTGATTTCACTCGCCGAAACCTTGAAGCTGACGGAAGAGCGGGCCGGGATCAATGTCCAGGTCGTCAATCCGGGTTT CGTCGAAACGCCGATGACAGCTCCCAATGATTTCTTCGAGATGCCGTTCCTGATGGATGCCGATGGCGCCGCCAGAAGAA TCTGCGATGGATTCGAAAGAGGCGGGTTCGAAATCACTTTCCCCAAGCGTCTTGCCTGGAGCTTCAAATTCGCCTGCCTG CTGCCTTATCCGCTGTTCTTTGCGATCATGCGGCGGGCGACGCGGCGCGTGCAATAA
Upstream 100 bases:
>100_bases CGGTGGATCAAGGGCGCAGTTTGATGAAAGACATCTTTCGTCAGCGTTGATTTGGTTTAGACTTGTGCCCCAATGGGGCA GGTGGAAGGTTTTCGGAAGC
Downstream 100 bases:
>100_bases GTCACGCGTCGGGATCCTCGGGCGCAAGCTCCTTGAGGCTTTCGGCGATCACGCCTACTTCCGTCCAATCGAGAGGGAGT GGCGGCTGGCGTGCCTGCAG
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 258; Mature: 257
Protein sequence:
>258_residues MAVYRARPRDGVAWVTGASSGIGRAVAMELARRGYRVAATARRKGDLEDLAAAMPNIISFPGDVTDLAGMRAMVKRIERQ LGPIALAFFNAGVYFIQERKGLAAEIAWRTFEVNTGGVLNCLDPLLPEMRRRRFGQIVLNASLAGYGGIPGSLAYGASKA ALISLAETLKLTEERAGINVQVVNPGFVETPMTAPNDFFEMPFLMDADGAARRICDGFERGGFEITFPKRLAWSFKFACL LPYPLFFAIMRRATRRVQ
Sequences:
>Translated_258_residues MAVYRARPRDGVAWVTGASSGIGRAVAMELARRGYRVAATARRKGDLEDLAAAMPNIISFPGDVTDLAGMRAMVKRIERQ LGPIALAFFNAGVYFIQERKGLAAEIAWRTFEVNTGGVLNCLDPLLPEMRRRRFGQIVLNASLAGYGGIPGSLAYGASKA ALISLAETLKLTEERAGINVQVVNPGFVETPMTAPNDFFEMPFLMDADGAARRICDGFERGGFEITFPKRLAWSFKFACL LPYPLFFAIMRRATRRVQ >Mature_257_residues AVYRARPRDGVAWVTGASSGIGRAVAMELARRGYRVAATARRKGDLEDLAAAMPNIISFPGDVTDLAGMRAMVKRIERQL GPIALAFFNAGVYFIQERKGLAAEIAWRTFEVNTGGVLNCLDPLLPEMRRRRFGQIVLNASLAGYGGIPGSLAYGASKAA LISLAETLKLTEERAGINVQVVNPGFVETPMTAPNDFFEMPFLMDADGAARRICDGFERGGFEITFPKRLAWSFKFACLL PYPLFFAIMRRATRRVQ
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=28.8557213930348, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=28.4263959390863, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI40254992, Length=193, Percent_Identity=34.1968911917098, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI210032110, Length=240, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI226371731, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI109715829, Length=198, Percent_Identity=31.3131313131313, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=31.0526315789474, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.8722466960352, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=30, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI223718074, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=30.4812834224599, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI126723750, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=33.6898395721925, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI87082100, Length=221, Percent_Identity=30.316742081448, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI2367175, Length=199, Percent_Identity=34.6733668341709, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786812, Length=182, Percent_Identity=34.0659340659341, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1786701, Length=186, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1789378, Length=196, Percent_Identity=29.5918367346939, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=27.8409090909091, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17567345, Length=230, Percent_Identity=28.695652173913, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17538486, Length=197, Percent_Identity=32.48730964467, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=28.0612244897959, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17565030, Length=202, Percent_Identity=32.6732673267327, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=29.0816326530612, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17551412, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538182, Length=195, Percent_Identity=31.2820512820513, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17560332, Length=201, Percent_Identity=31.8407960199005, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193204405, Length=197, Percent_Identity=29.9492385786802, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17538480, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17561402, Length=191, Percent_Identity=25.6544502617801, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=28.6458333333333, Blast_Score=68, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=34.5360824742268, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6320089, Length=205, Percent_Identity=27.8048780487805, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24649181, Length=246, Percent_Identity=28.0487804878049, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=30.3664921465969, Blast_Score=87, Evalue=2e-17, Organism=Drosophila melanogaster, GI116007236, Length=219, Percent_Identity=29.6803652968037, Blast_Score=84, Evalue=9e-17, Organism=Drosophila melanogaster, GI21355631, Length=252, Percent_Identity=26.984126984127, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28574402, Length=195, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24584744, Length=195, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=31.0880829015544, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI281364892, Length=246, Percent_Identity=26.8292682926829, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21356301, Length=186, Percent_Identity=31.1827956989247, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24643142, Length=186, Percent_Identity=36.5591397849462, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007238, Length=174, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=34.9206349206349, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24580925, Length=212, Percent_Identity=29.2452830188679, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571387, Length=223, Percent_Identity=28.6995515695067, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI28571526, Length=189, Percent_Identity=29.1005291005291, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24641232, Length=211, Percent_Identity=29.3838862559242, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24581726, Length=253, Percent_Identity=24.901185770751, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI116007234, Length=220, Percent_Identity=31.3636363636364, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 28303; Mature: 28172
Theoretical pI: Translated: 10.38; Mature: 10.38
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAVYRARPRDGVAWVTGASSGIGRAVAMELARRGYRVAATARRKGDLEDLAAAMPNIISF CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHCC PGDVTDLAGMRAMVKRIERQLGPIALAFFNAGVYFIQERKGLAAEIAWRTFEVNTGGVLN CCCHHHHHHHHHHHHHHHHHHCCEEEEEHHCCEEEEECCCCCEEEEEEEEEEECCCCHHH CLDPLLPEMRRRRFGQIVLNASLAGYGGIPGSLAYGASKAALISLAETLKLTEERAGINV HHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCEE QVVNPGFVETPMTAPNDFFEMPFLMDADGAARRICDGFERGGFEITFPKRLAWSFKFACL EEECCCCCCCCCCCCCCHHCCCEEECCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH LPYPLFFAIMRRATRRVQ HHHHHHHHHHHHHHHCCC >Mature Secondary Structure AVYRARPRDGVAWVTGASSGIGRAVAMELARRGYRVAATARRKGDLEDLAAAMPNIISF CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHCCCCHHHHHHHHHHHHCC PGDVTDLAGMRAMVKRIERQLGPIALAFFNAGVYFIQERKGLAAEIAWRTFEVNTGGVLN CCCHHHHHHHHHHHHHHHHHHCCEEEEEHHCCEEEEECCCCCEEEEEEEEEEECCCCHHH CLDPLLPEMRRRRFGQIVLNASLAGYGGIPGSLAYGASKAALISLAETLKLTEERAGINV HHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCEE QVVNPGFVETPMTAPNDFFEMPFLMDADGAARRICDGFERGGFEITFPKRLAWSFKFACL EEECCCCCCCCCCCCCCHHCCCEEECCCHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH LPYPLFFAIMRRATRRVQ HHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1730672 [H]