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The map label for this gene is cof

Identifier: 197294558

GI number: 197294558

Start: 506757

End: 507551

Strand: Reverse

Name: cof

Synonym: PAa_0513

Alternate gene names: NA

Gene position: 507551-506757 (Counterclockwise)

Preceding gene: 197294559

Following gene: 197294557

Centisome position: 57.68

GC content: 28.18

Gene sequence:

>795_bases
ATGAAACCAGCCAAAAAGATGTTTTTCTTTGATATTGACGGTACCCTTTTGAGTTCTAAATATAAACAAATTTTTTCTCA
AACTACTGAAGCAATCAAAAAATTAGCAAAACAGCCTGAAGTTATTTTAGGAATAGCTACCGGAAGAAATATAAAAAGAA
TTGATGTTTTAGGAGATTTGTTGCCTTATTTTAAACATTTAATTTTATTTAACGGAGGTTTGACGAAAGTTTTTGATAAA
ATCATCGATGATAGACCTTTTAAAAAAGAAGTAGTACAAGAATTAATAACAAAAGCACATGAAGCAAAAATTTATATTGG
TCTTACAGGTTTTGATCAAGAAATTATTCCGAGTGAAAAAGACTTAATCCCTACTTCTTTGCAAAAACTTTATTTTACTA
ATAAAAATTCTTTAGTTGATCCTGAATTTCATCTTCACAATAATGTTTATCAGGTTTGGTTATTTGAACCTAATCGCCAA
AAATTAGATAATTTTTTAAAAGATTTTCCTTATTTACAAAAATATTATTGGAGAAGTGATGGGGGGGCTGATTTAGTTCC
TGCAAATGTCAATAAAGTTACCGGAATCAAATTAATTAAAGATTTATATAAAGATTATCAATTGATTTGTGTAGGCGACG
GCCATAACGATGTTGATATGTTAAAGTACGCCGACATTGGTATAGGAATGAGTAACACTAGTTGCCAAGAAGTCAAAGAT
AACGCAGATCTTTTAGCTCCTAGTGTGGATAATAATAAATTTTATGATTTTTTAAAAGAAAATAATTTAATTTAA

Upstream 100 bases:

>100_bases
TTCTTAATTACAATTCGAAAACAGAATTAAAATCGTTAAAATAACAAATAATTTTTTGATTTTTATTTTTAAAGATAACA
ATAAGGAGTTTTTTTTGAAA

Downstream 100 bases:

>100_bases
AAAATGTGGTTTTATTTTTATCTTTTTCTAATTAGGAAATAATTTATTAATAATGATTTGAAATCAAAGAAAGCGTAAAA
TGAAATGTTAACTTCAGATA

Product: Putative hydrolases of the HAD superfamily subfamily IIB

Products: NA

Alternate protein names: Phosphatase; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKPAKKMFFFDIDGTLLSSKYKQIFSQTTEAIKKLAKQPEVILGIATGRNIKRIDVLGDLLPYFKHLILFNGGLTKVFDK
IIDDRPFKKEVVQELITKAHEAKIYIGLTGFDQEIIPSEKDLIPTSLQKLYFTNKNSLVDPEFHLHNNVYQVWLFEPNRQ
KLDNFLKDFPYLQKYYWRSDGGADLVPANVNKVTGIKLIKDLYKDYQLICVGDGHNDVDMLKYADIGIGMSNTSCQEVKD
NADLLAPSVDNNKFYDFLKENNLI

Sequences:

>Translated_264_residues
MKPAKKMFFFDIDGTLLSSKYKQIFSQTTEAIKKLAKQPEVILGIATGRNIKRIDVLGDLLPYFKHLILFNGGLTKVFDK
IIDDRPFKKEVVQELITKAHEAKIYIGLTGFDQEIIPSEKDLIPTSLQKLYFTNKNSLVDPEFHLHNNVYQVWLFEPNRQ
KLDNFLKDFPYLQKYYWRSDGGADLVPANVNKVTGIKLIKDLYKDYQLICVGDGHNDVDMLKYADIGIGMSNTSCQEVKD
NADLLAPSVDNNKFYDFLKENNLI
>Mature_264_residues
MKPAKKMFFFDIDGTLLSSKYKQIFSQTTEAIKKLAKQPEVILGIATGRNIKRIDVLGDLLPYFKHLILFNGGLTKVFDK
IIDDRPFKKEVVQELITKAHEAKIYIGLTGFDQEIIPSEKDLIPTSLQKLYFTNKNSLVDPEFHLHNNVYQVWLFEPNRQ
KLDNFLKDFPYLQKYYWRSDGGADLVPANVNKVTGIKLIKDLYKDYQLICVGDGHNDVDMLKYADIGIGMSNTSCQEVKD
NADLLAPSVDNNKFYDFLKENNLI

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR002130 [H]

Pfam domain/function: PF08282 Hydrolase_3; PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 30338; Mature: 30338

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAKKMFFFDIDGTLLSSKYKQIFSQTTEAIKKLAKQPEVILGIATGRNIKRIDVLGDL
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHH
LPYFKHLILFNGGLTKVFDKIIDDRPFKKEVVQELITKAHEAKIYIGLTGFDQEIIPSEK
HHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCC
DLIPTSLQKLYFTNKNSLVDPEFHLHNNVYQVWLFEPNRQKLDNFLKDFPYLQKYYWRSD
CCCHHHHHHHEEECCCCCCCCCCEECCCEEEEEEECCCHHHHHHHHHHCHHHHHHHHCCC
GGADLVPANVNKVTGIKLIKDLYKDYQLICVGDGHNDVDMLKYADIGIGMSNTSCQEVKD
CCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHC
NADLLAPSVDNNKFYDFLKENNLI
CCHHCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MKPAKKMFFFDIDGTLLSSKYKQIFSQTTEAIKKLAKQPEVILGIATGRNIKRIDVLGDL
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEHHHHHHHH
LPYFKHLILFNGGLTKVFDKIIDDRPFKKEVVQELITKAHEAKIYIGLTGFDQEIIPSEK
HHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCC
DLIPTSLQKLYFTNKNSLVDPEFHLHNNVYQVWLFEPNRQKLDNFLKDFPYLQKYYWRSD
CCCHHHHHHHEEECCCCCCCCCCEECCCEEEEEEECCCHHHHHHHHHHCHHHHHHHHCCC
GGADLVPANVNKVTGIKLIKDLYKDYQLICVGDGHNDVDMLKYADIGIGMSNTSCQEVKD
CCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHC
NADLLAPSVDNNKFYDFLKENNLI
CCHHCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA