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The map label for this gene is ackA

Identifier: 197294258

GI number: 197294258

Start: 134752

End: 135942

Strand: Direct

Name: ackA

Synonym: PAa_0121

Alternate gene names: 197294258

Gene position: 134752-135942 (Clockwise)

Preceding gene: 197294257

Following gene: 197294260

Centisome position: 15.31

GC content: 32.33

Gene sequence:

>1191_bases
ATGAAAATTATGTCGGTTAATTCAGGTAGCTCTTCTTTAAAATTTCAATTATTGGAAATGCCTCAAAAAAATTTAATCAC
TTCTGGTTTGATTGAAAGAATTGGTTCTAATAATGCCACTTTTACATTGAAAAACCAAAATCATAAAACTTCTAAAACCT
TAGAGATTAAAAACCATCAACAAGCAGTATCATTATTATTAACTTCTTTAATTGAAAATAAAATAATTGCTCGTTTAGAA
GATATTGATGGCGTGGGACATCGGATTGTTCAGGGTGGTGAATTGTTCCAAGATGCAACTGCTTTAAATGATGTAGAAAT
TGCCAAAATTGAAAGTCTTTGCGATTTGGCTCCTTTGCACAATCCAGCCAACCTCGTAAGTATTAAAGCTTTTCGCCAAG
TTTTGCCCTCTTTATTTCAAGTCGGCGTTTTTGATACTACCTTCCATCAAACTATTCCTGTAAAGAATTTTTTATATGCT
ACTCCTTATGCTTGGTATCAAAAATACAAAGTAAGAAAATACGGGTTTCATGGCATTTCTTACCAATATATTACCGAACA
AATGCAACAACTTTTGAATAAAAAAGATGCTAAATTAATTATTTGTCATGCTGGAAATGGTGTTTCTTTGTGTGCGGTTG
ATTCAGGTAAATCAATTGATACTTCAATGGGTTTCACTCCTTTAGAAGGTGTTCCTATGGGGACTCGTAGTGGTAATATT
GACCCTGCAGTAATTAAGTTTATCGCTGAAAAAGAAAACAAAGGTATTGCTGAAATAACAGATGATTTAAACAAAAAATC
GGGTTTACTTGGGGTTTCTACTATTTCCAACGATGCACGCGATATTCTTGCAGAAATTAAAAAGGGAAACCCTCAGGCTC
GTTTAGCTTTTGATATTCAAATAAAAAGAATTGTTGATTATATTGCTAGTTACTATGTTTTATTAAAAGGAATTGATGCT
TTAGTTTTTACTGCTGGTATTGGCGAGAATTCATCTTTTTTTAGATCAGAAATAATTAAGCGTTTATCTGTTTTGGGCTT
TCGATTAGATGAGCAAAAAAATGAAGTGCAAGGAAAAACTTCCGTTATTACTTCTTCTGATTCACTTCAGCAAGCTTTTG
TGGTTCCTACTAACGAAGAGCTTTCAATTGCTTGTGATGTTTTAAGGATTTATAAAAAAGTAAAAAAATAG

Upstream 100 bases:

>100_bases
TTTTAACTTTCATGTTTTATGATGAAAATAATTAAAATAAAATTTATAAAATCCAAATATTTACAAACTTTATATCTAAA
TAGAAAAGAGAAAAAAATAT

Downstream 100 bases:

>100_bases
TGTTTTTGAGTTTTTTATAATTTCAAAAATTCTTTTATGAGTTTTTCAAAAAAACTTTGTTTTTGTTTTTTTGGTGTGAT
TTTGTGATAAGTTTATTCAT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKIMSVNSGSSSLKFQLLEMPQKNLITSGLIERIGSNNATFTLKNQNHKTSKTLEIKNHQQAVSLLLTSLIENKIIARLE
DIDGVGHRIVQGGELFQDATALNDVEIAKIESLCDLAPLHNPANLVSIKAFRQVLPSLFQVGVFDTTFHQTIPVKNFLYA
TPYAWYQKYKVRKYGFHGISYQYITEQMQQLLNKKDAKLIICHAGNGVSLCAVDSGKSIDTSMGFTPLEGVPMGTRSGNI
DPAVIKFIAEKENKGIAEITDDLNKKSGLLGVSTISNDARDILAEIKKGNPQARLAFDIQIKRIVDYIASYYVLLKGIDA
LVFTAGIGENSSFFRSEIIKRLSVLGFRLDEQKNEVQGKTSVITSSDSLQQAFVVPTNEELSIACDVLRIYKKVKK

Sequences:

>Translated_396_residues
MKIMSVNSGSSSLKFQLLEMPQKNLITSGLIERIGSNNATFTLKNQNHKTSKTLEIKNHQQAVSLLLTSLIENKIIARLE
DIDGVGHRIVQGGELFQDATALNDVEIAKIESLCDLAPLHNPANLVSIKAFRQVLPSLFQVGVFDTTFHQTIPVKNFLYA
TPYAWYQKYKVRKYGFHGISYQYITEQMQQLLNKKDAKLIICHAGNGVSLCAVDSGKSIDTSMGFTPLEGVPMGTRSGNI
DPAVIKFIAEKENKGIAEITDDLNKKSGLLGVSTISNDARDILAEIKKGNPQARLAFDIQIKRIVDYIASYYVLLKGIDA
LVFTAGIGENSSFFRSEIIKRLSVLGFRLDEQKNEVQGKTSVITSSDSLQQAFVVPTNEELSIACDVLRIYKKVKK
>Mature_396_residues
MKIMSVNSGSSSLKFQLLEMPQKNLITSGLIERIGSNNATFTLKNQNHKTSKTLEIKNHQQAVSLLLTSLIENKIIARLE
DIDGVGHRIVQGGELFQDATALNDVEIAKIESLCDLAPLHNPANLVSIKAFRQVLPSLFQVGVFDTTFHQTIPVKNFLYA
TPYAWYQKYKVRKYGFHGISYQYITEQMQQLLNKKDAKLIICHAGNGVSLCAVDSGKSIDTSMGFTPLEGVPMGTRSGNI
DPAVIKFIAEKENKGIAEITDDLNKKSGLLGVSTISNDARDILAEIKKGNPQARLAFDIQIKRIVDYIASYYVLLKGIDA
LVFTAGIGENSSFFRSEIIKRLSVLGFRLDEQKNEVQGKTSVITSSDSLQQAFVVPTNEELSIACDVLRIYKKVKK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=394, Percent_Identity=36.8020304568528, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1788633, Length=398, Percent_Identity=38.4422110552764, Blast_Score=272, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_PHYAS (B1V924)

Other databases:

- EMBL:   AM422018
- RefSeq:   YP_001798799.1
- ProteinModelPortal:   B1V924
- SMR:   B1V924
- GeneID:   6799031
- GenomeReviews:   AM422018_GR
- HOGENOM:   HBG285863
- OMA:   WATEVAV
- ProtClustDB:   PRK00180
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43848; Mature: 43848

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMSVNSGSSSLKFQLLEMPQKNLITSGLIERIGSNNATFTLKNQNHKTSKTLEIKNHQ
CEEEEECCCCCCEEEHEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECHHH
QAVSLLLTSLIENKIIARLEDIDGVGHRIVQGGELFQDATALNDVEIAKIESLCDLAPLH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCC
NPANLVSIKAFRQVLPSLFQVGVFDTTFHQTIPVKNFLYATPYAWYQKYKVRKYGFHGIS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHEECCCHHHHHHHHHHHCCCCCCH
YQYITEQMQQLLNKKDAKLIICHAGNGVSLCAVDSGKSIDTSMGFTPLEGVPMGTRSGNI
HHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
DPAVIKFIAEKENKGIAEITDDLNKKSGLLGVSTISNDARDILAEIKKGNPQARLAFDIQ
CHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEE
IKRIVDYIASYYVLLKGIDALVFTAGIGENSSFFRSEIIKRLSVLGFRLDEQKNEVQGKT
HHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
SVITSSDSLQQAFVVPTNEELSIACDVLRIYKKVKK
EEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIMSVNSGSSSLKFQLLEMPQKNLITSGLIERIGSNNATFTLKNQNHKTSKTLEIKNHQ
CEEEEECCCCCCEEEHEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECHHH
QAVSLLLTSLIENKIIARLEDIDGVGHRIVQGGELFQDATALNDVEIAKIESLCDLAPLH
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCCC
NPANLVSIKAFRQVLPSLFQVGVFDTTFHQTIPVKNFLYATPYAWYQKYKVRKYGFHGIS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHEECCCHHHHHHHHHHHCCCCCCH
YQYITEQMQQLLNKKDAKLIICHAGNGVSLCAVDSGKSIDTSMGFTPLEGVPMGTRSGNI
HHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
DPAVIKFIAEKENKGIAEITDDLNKKSGLLGVSTISNDARDILAEIKKGNPQARLAFDIQ
CHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEE
IKRIVDYIASYYVLLKGIDALVFTAGIGENSSFFRSEIIKRLSVLGFRLDEQKNEVQGKT
HHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
SVITSSDSLQQAFVVPTNEELSIACDVLRIYKKVKK
EEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA