Click here to switch to the map view.

The map label for this gene is 170757489

Identifier: 170757489

GI number: 170757489

Start: 2887967

End: 2888971

Strand: Reverse

Name: 170757489

Synonym: CLD_1854

Alternate gene names: NA

Gene position: 2888971-2887967 (Counterclockwise)

Preceding gene: 170756742

Following gene: 170756683

Centisome position: 72.99

GC content: 40.4

Gene sequence:

>1005_bases
ATGTCAGTATTAATAATTGCAGAAGCGGGAGTCAATCATAATGGAGATGTCAAAATAGCAAAAGAACTTGTGGACATGGC
TGTTGAATGTGGAGCAGATGCCATAAAGTTTCAAACCTTCAAGGCTGAAGAAAGCACAGGCTCATTTGCTGAAAAAGCGC
AGTATCAGAAGGAAAATGATCAAACTGAGGAATCACAGCTTGAAATGATAAAAAAACTTGAATTGCCCTTTGAACAGTTT
GATGGAATTCAAAGTTACTGCAATGAAAAAAACATTGTTTTCATATCCACCCCCGACGGTATGGGAAGCTTGAATTATTT
AGTCGGGTTGAATGTACCGTTAATTAAAATAGGATCTACTGAAGTTACAAATTATGAGTTTCTGAGGAAGATAGGAGAAA
CAGAAAAGCCTGTAATTTTGTCTACAGGAATGAGTACCTTGGGAGAAGTGGAAAAAGCACTGGAGGTCATATCTTCTACA
GGAAACAAGGATGTGAAGCTGATGCATTGTACCACGGATTATCCGACAGCTGTCGAGGATGTGAACTTGAGAGCCATGGT
TACCATGAGGGAAGCTTTCAAAGTGCCTGTTGGATTGTCCGATCATACCACAGGCTCTGAAGCTGCAATAGCAGCAGTGG
CATTGGGAGCTGAATTCATAGAAAAACACATCACCCTTGATAGAAACATGGAAGGGCCGGACCATAAGGCATCCATGCCT
CCAGAAGAGTTCAAGGGATATGTTCGTCATATAAGAAATGCTGAAAAATTGCTGGGTGATGGAATAAAGAAGCCTACTGA
AAGAGAAATTATCATAATGCAGGACATAAGAAGAAGCATTGTTGCTGGGTGTGACTTGAAAAAAGGAACCAATATAGAAG
TACACATGCTTTCGTATAAGAGACCTGGTACTGGAATAAAGCCAGAATTGGCCCATGTTCTAGTTGGCAGAGAACTAAAG
AGAGATTTGAAAAAGGGTGAGGTCATACAATGGAAGGACATATGA

Upstream 100 bases:

>100_bases
TATGGAGAAGGAAATACCAGTGAAGAAATAGTCAAGGTGCTGGAAAGCATCGAAATTAATGATGAATTATTAAAAAAGAA
ACTTGTTTGGAGTTGATAAC

Downstream 100 bases:

>100_bases
AACCCATAGGTGGAGAACTTTGGTTTGACGAAATCATATTTAATGATGCTGAAAACAATTTTCAACATTTGAATGCAGTA
TTTTTAAATGGCGGGCAAAG

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSVLIIAEAGVNHNGDVKIAKELVDMAVECGADAIKFQTFKAEESTGSFAEKAQYQKENDQTEESQLEMIKKLELPFEQF
DGIQSYCNEKNIVFISTPDGMGSLNYLVGLNVPLIKIGSTEVTNYEFLRKIGETEKPVILSTGMSTLGEVEKALEVISST
GNKDVKLMHCTTDYPTAVEDVNLRAMVTMREAFKVPVGLSDHTTGSEAAIAAVALGAEFIEKHITLDRNMEGPDHKASMP
PEEFKGYVRHIRNAEKLLGDGIKKPTEREIIIMQDIRRSIVAGCDLKKGTNIEVHMLSYKRPGTGIKPELAHVLVGRELK
RDLKKGEVIQWKDI

Sequences:

>Translated_334_residues
MSVLIIAEAGVNHNGDVKIAKELVDMAVECGADAIKFQTFKAEESTGSFAEKAQYQKENDQTEESQLEMIKKLELPFEQF
DGIQSYCNEKNIVFISTPDGMGSLNYLVGLNVPLIKIGSTEVTNYEFLRKIGETEKPVILSTGMSTLGEVEKALEVISST
GNKDVKLMHCTTDYPTAVEDVNLRAMVTMREAFKVPVGLSDHTTGSEAAIAAVALGAEFIEKHITLDRNMEGPDHKASMP
PEEFKGYVRHIRNAEKLLGDGIKKPTEREIIIMQDIRRSIVAGCDLKKGTNIEVHMLSYKRPGTGIKPELAHVLVGRELK
RDLKKGEVIQWKDI
>Mature_333_residues
SVLIIAEAGVNHNGDVKIAKELVDMAVECGADAIKFQTFKAEESTGSFAEKAQYQKENDQTEESQLEMIKKLELPFEQFD
GIQSYCNEKNIVFISTPDGMGSLNYLVGLNVPLIKIGSTEVTNYEFLRKIGETEKPVILSTGMSTLGEVEKALEVISSTG
NKDVKLMHCTTDYPTAVEDVNLRAMVTMREAFKVPVGLSDHTTGSEAAIAAVALGAEFIEKHITLDRNMEGPDHKASMPP
EEFKGYVRHIRNAEKLLGDGIKKPTEREIIIMQDIRRSIVAGCDLKKGTNIEVHMLSYKRPGTGIKPELAHVLVGRELKR
DLKKGEVIQWKDI

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=320, Percent_Identity=34.0625, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21357081, Length=353, Percent_Identity=31.728045325779, Blast_Score=167, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 36996; Mature: 36865

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLIIAEAGVNHNGDVKIAKELVDMAVECGADAIKFQTFKAEESTGSFAEKAQYQKEND
CEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
QTEESQLEMIKKLELPFEQFDGIQSYCNEKNIVFISTPDGMGSLNYLVGLNVPLIKIGST
CCHHHHHHHHHHHCCCHHHHCCHHHHHCCCCEEEEECCCCCCCCEEEEECCCCEEEECCC
EVTNYEFLRKIGETEKPVILSTGMSTLGEVEKALEVISSTGNKDVKLMHCTTDYPTAVED
CCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHC
VNLRAMVTMREAFKVPVGLSDHTTGSEAAIAAVALGAEFIEKHITLDRNMEGPDHKASMP
CCHHEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEEFKGYVRHIRNAEKLLGDGIKKPTEREIIIMQDIRRSIVAGCDLKKGTNIEVHMLSYK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEEEEEEC
RPGTGIKPELAHVLVGRELKRDLKKGEVIQWKDI
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECC
>Mature Secondary Structure 
SVLIIAEAGVNHNGDVKIAKELVDMAVECGADAIKFQTFKAEESTGSFAEKAQYQKEND
EEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
QTEESQLEMIKKLELPFEQFDGIQSYCNEKNIVFISTPDGMGSLNYLVGLNVPLIKIGST
CCHHHHHHHHHHHCCCHHHHCCHHHHHCCCCEEEEECCCCCCCCEEEEECCCCEEEECCC
EVTNYEFLRKIGETEKPVILSTGMSTLGEVEKALEVISSTGNKDVKLMHCTTDYPTAVED
CCCCHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHC
VNLRAMVTMREAFKVPVGLSDHTTGSEAAIAAVALGAEFIEKHITLDRNMEGPDHKASMP
CCHHEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PEEFKGYVRHIRNAEKLLGDGIKKPTEREIIIMQDIRRSIVAGCDLKKGTNIEVHMLSYK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEEEEEEC
RPGTGIKPELAHVLVGRELKRDLKKGEVIQWKDI
CCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]