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The map label for this gene is dtpT [H]

Identifier: 170757363

GI number: 170757363

Start: 2175858

End: 2177204

Strand: Reverse

Name: dtpT [H]

Synonym: CLD_2597

Alternate gene names: 170757363

Gene position: 2177204-2175858 (Counterclockwise)

Preceding gene: 170756275

Following gene: 170756861

Centisome position: 55.0

GC content: 36.3

Gene sequence:

>1347_bases
ATGGAAAACACAAACAAAAAACCATTTGGGTTTTATGTATGCTCAGTTGCTTTCACACTTGAAAGATTTGCATTCTACTC
AGCAAAATGGCTACTTGCAGTATTCGTAGTTGCTAAAATAGCGGACGGAGGACTTGGTCTTTCTGCTGCAGAAGCAGCAA
AAATGTCTGCAAACTTAGTTGCATTTACTTACGCTGCACCATTAATAGGGGCATTTATATCTGACCGTTTTGTAGGTGCT
AGATACCTTGTTCCAATCGGAATGGTTTTAATGGGGGCAGGTTATTTGGTAGGATGGCAAGCTTCAAGTGCTGGCATGGT
TAACTTAATGATTGTCCTAGTTTCTCTTGGTACAGGATTATTTAAATGTCAAACAAACGCTATTACAGGTAGACTTTTTG
ATGATCCAAGACAATTAGATAGTGCTTTCTCTGTTCAATATTCTTTTGTTAATATTGGTTCTTTCATTGGTACAACAATT
ATCGGTGTACTTGTAGGAACTAAGGGATATGCTTTCTGTTTCTTAGTTTGTGGAATAATGATGTTTATTGATGCCGCTTG
GTTTACCTTTGGATGGAGATTTTTAGGAGAAACAGGTAAAAAGCCATTCAAAATTGATGAACACGAAGAAGTAAAAGTAA
AAGAAACTAAGGAAGAAAAGAAGCCACTTACATCAATAGAAAAGAAAAGGGTTGCAGCAATTATATTAGTATCTTTCTTC
TCTGTAATTTTCTGGGTGTTCTGGTACTTAGCATATATGCCTGTATACTTCTACTGGGGCGGAGATAATGCAGCGGCTAA
CTGGATGATAGGTAATTTTCAAGTTCCAACAGCTTGGTTTGATTCATTAAATGCATTAGCATGTATCACATTAGGACCAA
TTCTTGGTAGAGTTTGGTCAAAATTAGCTAAAAGACCTCAAGGTGATTTAAGCATGTTTAAGAAAACTGCGTTAGGTATG
ATACTTTTAGGTTTATCCTATGTAATCTTTGCAATGGCAGATGTTACAAGAGGAGGTAATCTTGCATCACTTGCTTGGAT
TGTTGCATTTGGTATCGTATTATCTCTTGGTGAAATGGTATTCTCACCACTTGGAAACTCTTTCATTAGTAAATTTTCAC
CACCTAAATTATTATCAAGCATGATGAGTGTTTGGGTACTTGCGGTTTTCTTCGCAGCAAAATCTTATGGATGGGTATAT
GAATTTACACTAAAATTTAAATTCGCACCAACATACTTTGTAATCGCAGCTATTGCTGCTGGAGCAGGTGTAATACTTTG
GTTATTAGATGGGAAATTGAATAGCTTAGTTGTAGAAGAGGAAGAACCATTAAACGAAGCTGTTTAA

Upstream 100 bases:

>100_bases
TATGGTATTTGAAATTATTTCATATCCTCTGTAAAAAGAGGAGGGGGAATAGTTTTTAAAATACACACGCAATATTAATT
TTTTATAGGGGGAATAAAAA

Downstream 100 bases:

>100_bases
TTAATGTAAAAATTTATATTAATATGAAATTTTATAGAATATTTATTTAAAGAAGTCATTGTTTTTCAATGGCTTCTTTT
TTTATAACTTTTTTATTTTT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MENTNKKPFGFYVCSVAFTLERFAFYSAKWLLAVFVVAKIADGGLGLSAAEAAKMSANLVAFTYAAPLIGAFISDRFVGA
RYLVPIGMVLMGAGYLVGWQASSAGMVNLMIVLVSLGTGLFKCQTNAITGRLFDDPRQLDSAFSVQYSFVNIGSFIGTTI
IGVLVGTKGYAFCFLVCGIMMFIDAAWFTFGWRFLGETGKKPFKIDEHEEVKVKETKEEKKPLTSIEKKRVAAIILVSFF
SVIFWVFWYLAYMPVYFYWGGDNAAANWMIGNFQVPTAWFDSLNALACITLGPILGRVWSKLAKRPQGDLSMFKKTALGM
ILLGLSYVIFAMADVTRGGNLASLAWIVAFGIVLSLGEMVFSPLGNSFISKFSPPKLLSSMMSVWVLAVFFAAKSYGWVY
EFTLKFKFAPTYFVIAAIAAGAGVILWLLDGKLNSLVVEEEEPLNEAV

Sequences:

>Translated_448_residues
MENTNKKPFGFYVCSVAFTLERFAFYSAKWLLAVFVVAKIADGGLGLSAAEAAKMSANLVAFTYAAPLIGAFISDRFVGA
RYLVPIGMVLMGAGYLVGWQASSAGMVNLMIVLVSLGTGLFKCQTNAITGRLFDDPRQLDSAFSVQYSFVNIGSFIGTTI
IGVLVGTKGYAFCFLVCGIMMFIDAAWFTFGWRFLGETGKKPFKIDEHEEVKVKETKEEKKPLTSIEKKRVAAIILVSFF
SVIFWVFWYLAYMPVYFYWGGDNAAANWMIGNFQVPTAWFDSLNALACITLGPILGRVWSKLAKRPQGDLSMFKKTALGM
ILLGLSYVIFAMADVTRGGNLASLAWIVAFGIVLSLGEMVFSPLGNSFISKFSPPKLLSSMMSVWVLAVFFAAKSYGWVY
EFTLKFKFAPTYFVIAAIAAGAGVILWLLDGKLNSLVVEEEEPLNEAV
>Mature_448_residues
MENTNKKPFGFYVCSVAFTLERFAFYSAKWLLAVFVVAKIADGGLGLSAAEAAKMSANLVAFTYAAPLIGAFISDRFVGA
RYLVPIGMVLMGAGYLVGWQASSAGMVNLMIVLVSLGTGLFKCQTNAITGRLFDDPRQLDSAFSVQYSFVNIGSFIGTTI
IGVLVGTKGYAFCFLVCGIMMFIDAAWFTFGWRFLGETGKKPFKIDEHEEVKVKETKEEKKPLTSIEKKRVAAIILVSFF
SVIFWVFWYLAYMPVYFYWGGDNAAANWMIGNFQVPTAWFDSLNALACITLGPILGRVWSKLAKRPQGDLSMFKKTALGM
ILLGLSYVIFAMADVTRGGNLASLAWIVAFGIVLSLGEMVFSPLGNSFISKFSPPKLLSSMMSVWVLAVFFAAKSYGWVY
EFTLKFKFAPTYFVIAAIAAGAGVILWLLDGKLNSLVVEEEEPLNEAV

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=426, Percent_Identity=25.5868544600939, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789911, Length=436, Percent_Identity=24.3119266055046, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786927, Length=430, Percent_Identity=23.2558139534884, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790572, Length=423, Percent_Identity=22.2222222222222, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49183; Mature: 49183

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEEEEEECCCCCCEEECCCCCCCCCC
>Mature Secondary Structure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CCCEEEEEECCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]