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The map label for this gene is dtpT [H]

Identifier: 170756861

GI number: 170756861

Start: 2174189

End: 2175541

Strand: Reverse

Name: dtpT [H]

Synonym: CLD_2598

Alternate gene names: 170756861

Gene position: 2175541-2174189 (Counterclockwise)

Preceding gene: 170757363

Following gene: 170755208

Centisome position: 54.96

GC content: 34.22

Gene sequence:

>1353_bases
ATGGAAAACACAAGTAAAAAACCATTGGGGTTTTATGTATGCTCACTGGCTTTCACATTCGAAAGATTTGCATTCTATTC
AGCAAAATGGTTAATTGCAGTATTTGTAGTTGCTAAAGTAGCTAGTGGAGGACTTGGACTTTCAGCTGCAGAAGGGGCAA
AAATGTCTGCAAATTTAGTTGCATGGACATACTTTGCACCATTGATTGGGGCATATATATCTGATCGTAAAATAGGGGCA
AGATATCTTATTCCAGTAGGAATGATTTTAATGGGGGCAGGATACTTAGTAGGATGGAAGGCCTCAAGTGCTGGTATGGT
TAACTTAATGATTATTTTGGTTTCTATAGGGACAGGTTTATTTAAATGTCAAAACAATGCTATTACTGGAAGACTTTTTG
ATAACCAAGAAGAATTAGATAGTGCATTTTCTATTCAGTATTCCTATGTTAATGTAGGTTCTTTCATAGGTACAACAGTT
TTAGGTGTACTTGCAGGAAGTATGGGATATTCTTTCTGTTTCTTAATTTGTGCAATTATGATGTTTTTTGATGCTGCTTT
CTTTATCTTCGGATGGAGATATTTAGGAGAAGCGGGTAAAAAACCATTTAAGATTGATGAGCACAAAGAAGTAAAAGAAC
AGAAACAAGAAGAAAAGAAACCTCTTACAAAAATAGAAAAGAAAAGAATTGGAGCTATTATTTTAATATCTTTCTTCTCT
GTAATTTTCTGGGTATTCTGGCAATTAGCATATCTGCCTGTATATTACTACTGGGGCGGAGACAATGGACTTGCTAACTG
GATGATAGGTAGTTTTCAGGTACCGACAGCTTGGTTTGACTCATTAAATGCATTATGCTGTATTGTATTAGGACCAGTTC
TTGCTAAAGTATGGGAAAGATTAGCTAAAAGACCTAAAGGAGATATGAGTATGTTTAAGAAAACTGCTTTAGGTATGTTG
CTTTTAGGTTTATCTTATATAATATTTGCAATGGCAGATGTTACAAGAGGAAATAATCTTTTACCTCTTGCTTGGCTTGT
TGTATTTGGTATTGTATTAGCTCTTGGTGAAATGGTATTCTCACCACTTGGAAACTCATTTATAAGTAAATTTTCTCCTG
GTAGAATGTTGACAGCTATGATGAGTGTTTGGGTGCTTGCTAGCTTTGTTGCAGGAAAATCCTATGGATATGTATATGAA
TTTACACTAAAATTTAAATTTGCACCGACATATTTTGTAATAGCAGCAATTGCTATTGTGTGTGGCATTATTCTTTGGGC
ATTAGATGGAAAATTGAATAGTTTAGTTATAGATGAGAAGGTTGTGGAAGATAATTCTGTAAGTTTAAATTAA

Upstream 100 bases:

>100_bases
CTTTGGTATTTAAAACCATTGTACATAATCTTGAAAAAGATAGAGGCACATGGTTTTTAAAATACACATGCAATATTAAT
TATTAGAGGGGGAATAAAAA

Downstream 100 bases:

>100_bases
AATTCCACTTGCATACTTTACAATTGTAGATATTACTATTGTAAATGGTATCATTATTTAATCATTATATGAAATTTAAG
GGCAGTCATTTGACTGCCTT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MENTSKKPLGFYVCSLAFTFERFAFYSAKWLIAVFVVAKVASGGLGLSAAEGAKMSANLVAWTYFAPLIGAYISDRKIGA
RYLIPVGMILMGAGYLVGWKASSAGMVNLMIILVSIGTGLFKCQNNAITGRLFDNQEELDSAFSIQYSYVNVGSFIGTTV
LGVLAGSMGYSFCFLICAIMMFFDAAFFIFGWRYLGEAGKKPFKIDEHKEVKEQKQEEKKPLTKIEKKRIGAIILISFFS
VIFWVFWQLAYLPVYYYWGGDNGLANWMIGSFQVPTAWFDSLNALCCIVLGPVLAKVWERLAKRPKGDMSMFKKTALGML
LLGLSYIIFAMADVTRGNNLLPLAWLVVFGIVLALGEMVFSPLGNSFISKFSPGRMLTAMMSVWVLASFVAGKSYGYVYE
FTLKFKFAPTYFVIAAIAIVCGIILWALDGKLNSLVIDEKVVEDNSVSLN

Sequences:

>Translated_450_residues
MENTSKKPLGFYVCSLAFTFERFAFYSAKWLIAVFVVAKVASGGLGLSAAEGAKMSANLVAWTYFAPLIGAYISDRKIGA
RYLIPVGMILMGAGYLVGWKASSAGMVNLMIILVSIGTGLFKCQNNAITGRLFDNQEELDSAFSIQYSYVNVGSFIGTTV
LGVLAGSMGYSFCFLICAIMMFFDAAFFIFGWRYLGEAGKKPFKIDEHKEVKEQKQEEKKPLTKIEKKRIGAIILISFFS
VIFWVFWQLAYLPVYYYWGGDNGLANWMIGSFQVPTAWFDSLNALCCIVLGPVLAKVWERLAKRPKGDMSMFKKTALGML
LLGLSYIIFAMADVTRGNNLLPLAWLVVFGIVLALGEMVFSPLGNSFISKFSPGRMLTAMMSVWVLASFVAGKSYGYVYE
FTLKFKFAPTYFVIAAIAIVCGIILWALDGKLNSLVIDEKVVEDNSVSLN
>Mature_450_residues
MENTSKKPLGFYVCSLAFTFERFAFYSAKWLIAVFVVAKVASGGLGLSAAEGAKMSANLVAWTYFAPLIGAYISDRKIGA
RYLIPVGMILMGAGYLVGWKASSAGMVNLMIILVSIGTGLFKCQNNAITGRLFDNQEELDSAFSIQYSYVNVGSFIGTTV
LGVLAGSMGYSFCFLICAIMMFFDAAFFIFGWRYLGEAGKKPFKIDEHKEVKEQKQEEKKPLTKIEKKRIGAIILISFFS
VIFWVFWQLAYLPVYYYWGGDNGLANWMIGSFQVPTAWFDSLNALCCIVLGPVLAKVWERLAKRPKGDMSMFKKTALGML
LLGLSYIIFAMADVTRGNNLLPLAWLVVFGIVLALGEMVFSPLGNSFISKFSPGRMLTAMMSVWVLASFVAGKSYGYVYE
FTLKFKFAPTYFVIAAIAIVCGIILWALDGKLNSLVIDEKVVEDNSVSLN

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=436, Percent_Identity=23.394495412844, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789911, Length=439, Percent_Identity=22.3234624145786, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786927, Length=421, Percent_Identity=22.5653206650831, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790572, Length=449, Percent_Identity=20.9354120267261, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49755; Mature: 49755

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTSKKPLGFYVCSLAFTFERFAFYSAKWLIAVFVVAKVASGGLGLSAAEGAKMSANLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AWTYFAPLIGAYISDRKIGARYLIPVGMILMGAGYLVGWKASSAGMVNLMIILVSIGTGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCC
FKCQNNAITGRLFDNQEELDSAFSIQYSYVNVGSFIGTTVLGVLAGSMGYSFCFLICAIM
EEECCCCEEEEECCCHHHHCHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFFDAAFFIFGWRYLGEAGKKPFKIDEHKEVKEQKQEEKKPLTKIEKKRIGAIILISFFS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VIFWVFWQLAYLPVYYYWGGDNGLANWMIGSFQVPTAWFDSLNALCCIVLGPVLAKVWER
HHHHHHHHHHHHHEEEEECCCCCCHHHEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHH
LAKRPKGDMSMFKKTALGMLLLGLSYIIFAMADVTRGNNLLPLAWLVVFGIVLALGEMVF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SPLGNSFISKFSPGRMLTAMMSVWVLASFVAGKSYGYVYEFTLKFKFAPTYFVIAAIAIV
HHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHHH
CGIILWALDGKLNSLVIDEKVVEDNSVSLN
HHHHHHHHCCCCCCEEECHHHCCCCCCCCC
>Mature Secondary Structure
MENTSKKPLGFYVCSLAFTFERFAFYSAKWLIAVFVVAKVASGGLGLSAAEGAKMSANLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHH
AWTYFAPLIGAYISDRKIGARYLIPVGMILMGAGYLVGWKASSAGMVNLMIILVSIGTGL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCCC
FKCQNNAITGRLFDNQEELDSAFSIQYSYVNVGSFIGTTVLGVLAGSMGYSFCFLICAIM
EEECCCCEEEEECCCHHHHCHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFFDAAFFIFGWRYLGEAGKKPFKIDEHKEVKEQKQEEKKPLTKIEKKRIGAIILISFFS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VIFWVFWQLAYLPVYYYWGGDNGLANWMIGSFQVPTAWFDSLNALCCIVLGPVLAKVWER
HHHHHHHHHHHHHEEEEECCCCCCHHHEECCEECCHHHHHHHHHHHHHHHHHHHHHHHHH
LAKRPKGDMSMFKKTALGMLLLGLSYIIFAMADVTRGNNLLPLAWLVVFGIVLALGEMVF
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SPLGNSFISKFSPGRMLTAMMSVWVLASFVAGKSYGYVYEFTLKFKFAPTYFVIAAIAIV
HHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECHHHHHHHHHHHH
CGIILWALDGKLNSLVIDEKVVEDNSVSLN
HHHHHHHHCCCCCCEEECHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]