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The map label for this gene is arnA [H]

Identifier: 170757334

GI number: 170757334

Start: 2890806

End: 2891693

Strand: Reverse

Name: arnA [H]

Synonym: CLD_1851

Alternate gene names: 170757334

Gene position: 2891693-2890806 (Counterclockwise)

Preceding gene: 170754454

Following gene: 170757542

Centisome position: 73.06

GC content: 29.5

Gene sequence:

>888_bases
ATGAGAATTGTGTATATTGGAGTTGTAGAATTCAGCCATATATGTTTGGAAGAAATCATAAAAAATAAGGGAGAGGTTGT
AGGGGTATTAACTAAAAAGCGATCTAAATATAATAGTGATTTTTGTGACTTAACTCCTATATCAGAAAAAAATAACATAG
ATATAAAGTATTTTGATAACATAAATGATAATGAAAATATTGAATGGATTAAAGCAAAAAAACCTGACATTATTTTTTGC
TTTGGATTATCACAATTAATTAAGGATGAAATTTTAAACATCGCTCCTATGGGAGTTATTGGTTGCCATGATACAATGCT
TCCGCAAAATAGAGGAAGACATCCAATTATATGGGCTCTTGCATTAGGCTTAAAAGAAACAGGACAAACATTTTTTGTTA
TGAATAAAGATGCAGATACTGGATTAATACTATCTCAAAGAAGTCTTAAAATTGAGGATAATGATAATGCAAAAACATTA
TATAATAAAATAAATCAATTGGCTTGCGAGCAAATAAGAGACTTTTTGCCTAAGTTAATAAATAAAACTTATGACTTGAT
TGAGCAGGATAAAAAATTAGCTAATTCGTGGAGAAAGAGAACTAGAAAAGATGGAATCATAGATTGGAGAATGAGCACAG
AAGCAATATTAAATTTAATAAAAGCATTAACAAAACCTTATCCAGGTGCTGAATTTGAATATAATGGTCAATTCATTACC
ATATGGGAAGCTACAAAATATGAATGTGATAAGTGTTATAACAATATTGAACCGGGAAAAGTTGTAAAGGTAATAGGAGA
TTGTCCTATAGTAAAGTGCTATGACAGTTTGATTAAATTGGTTGAATATGAGCCGCGGATAACTTTAAAGGAAGGTGAAT
ACTTGTAA

Upstream 100 bases:

>100_bases
TTACAGGATTCATTATGAGAAACAAGAAATCCTTGGATATTGATGATAATGAAGACTTTATGTTAGCTGATTTATTAATT
AAGAACAAAGGTGATGCAAA

Downstream 100 bases:

>100_bases
TGAAGGTATTAGTAATAGCAGTTCACCCAGACGATGAAACTTTAGGATGTGGAGGAACTATATTAAAACATGTTGATAAT
AATGATGAAGTTCATTGGTT

Product: bifunctional polymyxin resistance protein ArnA

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRIVYIGVVEFSHICLEEIIKNKGEVVGVLTKKRSKYNSDFCDLTPISEKNNIDIKYFDNINDNENIEWIKAKKPDIIFC
FGLSQLIKDEILNIAPMGVIGCHDTMLPQNRGRHPIIWALALGLKETGQTFFVMNKDADTGLILSQRSLKIEDNDNAKTL
YNKINQLACEQIRDFLPKLINKTYDLIEQDKKLANSWRKRTRKDGIIDWRMSTEAILNLIKALTKPYPGAEFEYNGQFIT
IWEATKYECDKCYNNIEPGKVVKVIGDCPIVKCYDSLIKLVEYEPRITLKEGEYL

Sequences:

>Translated_295_residues
MRIVYIGVVEFSHICLEEIIKNKGEVVGVLTKKRSKYNSDFCDLTPISEKNNIDIKYFDNINDNENIEWIKAKKPDIIFC
FGLSQLIKDEILNIAPMGVIGCHDTMLPQNRGRHPIIWALALGLKETGQTFFVMNKDADTGLILSQRSLKIEDNDNAKTL
YNKINQLACEQIRDFLPKLINKTYDLIEQDKKLANSWRKRTRKDGIIDWRMSTEAILNLIKALTKPYPGAEFEYNGQFIT
IWEATKYECDKCYNNIEPGKVVKVIGDCPIVKCYDSLIKLVEYEPRITLKEGEYL
>Mature_295_residues
MRIVYIGVVEFSHICLEEIIKNKGEVVGVLTKKRSKYNSDFCDLTPISEKNNIDIKYFDNINDNENIEWIKAKKPDIIFC
FGLSQLIKDEILNIAPMGVIGCHDTMLPQNRGRHPIIWALALGLKETGQTFFVMNKDADTGLILSQRSLKIEDNDNAKTL
YNKINQLACEQIRDFLPKLINKTYDLIEQDKKLANSWRKRTRKDGIIDWRMSTEAILNLIKALTKPYPGAEFEYNGQFIT
IWEATKYECDKCYNNIEPGKVVKVIGDCPIVKCYDSLIKLVEYEPRITLKEGEYL

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=275, Percent_Identity=26.9090909090909, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788589, Length=284, Percent_Identity=29.2253521126761, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789683, Length=289, Percent_Identity=24.9134948096886, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI133930964, Length=256, Percent_Identity=26.171875, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 34055; Mature: 34055

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVYIGVVEFSHICLEEIIKNKGEVVGVLTKKRSKYNSDFCDLTPISEKNNIDIKYFDN
CEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCEEEEEECC
INDNENIEWIKAKKPDIIFCFGLSQLIKDEILNIAPMGVIGCHDTMLPQNRGRHPIIWAL
CCCCCCEEEEECCCCCEEEEECHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEE
ALGLKETGQTFFVMNKDADTGLILSQRSLKIEDNDNAKTLYNKINQLACEQIRDFLPKLI
EHHHHHCCCEEEEEECCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NKTYDLIEQDKKLANSWRKRTRKDGIIDWRMSTEAILNLIKALTKPYPGAEFEYNGQFIT
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEECCCEEE
IWEATKYECDKCYNNIEPGKVVKVIGDCPIVKCYDSLIKLVEYEPRITLKEGEYL
EEECCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MRIVYIGVVEFSHICLEEIIKNKGEVVGVLTKKRSKYNSDFCDLTPISEKNNIDIKYFDN
CEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCCCCCCCCCEEEEEECC
INDNENIEWIKAKKPDIIFCFGLSQLIKDEILNIAPMGVIGCHDTMLPQNRGRHPIIWAL
CCCCCCEEEEECCCCCEEEEECHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEEE
ALGLKETGQTFFVMNKDADTGLILSQRSLKIEDNDNAKTLYNKINQLACEQIRDFLPKLI
EHHHHHCCCEEEEEECCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NKTYDLIEQDKKLANSWRKRTRKDGIIDWRMSTEAILNLIKALTKPYPGAEFEYNGQFIT
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEECCCEEE
IWEATKYECDKCYNNIEPGKVVKVIGDCPIVKCYDSLIKLVEYEPRITLKEGEYL
EEECCHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA