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The map label for this gene is yfnH [H]

Identifier: 170757000

GI number: 170757000

Start: 2892390

End: 2893466

Strand: Reverse

Name: yfnH [H]

Synonym: CLD_1849

Alternate gene names: 170757000

Gene position: 2893466-2892390 (Counterclockwise)

Preceding gene: 170754997

Following gene: 170754454

Centisome position: 73.1

GC content: 30.45

Gene sequence:

>1077_bases
ATGAAAAATTTAGGTAATATTCTTGTATGCGAAAGTACAACCTTATTGGAAACTTTAAATGCTATTAATCTTAATCAAAA
AGGAACTGCTATAGTAGTTGACAAGGAAAATAAGCTTTTGGGTACAATTACGGATGGAGACATAAGGCGAGCCATATTGG
AAAATATTTCGTTAAACTCCAGCATAAAAAACATATACAATAAAAATTGCATATGTTTCAATGAAAGTTATGATTTAACA
AAAGCAATGCAGTATTTTACTAAATCAATTAAATTGATTCCTATTATCAACAAAAATCAAAAGGTAACAAGTTATCTGGA
ATTAACAGATGTTCTGTTGCTTGAGTCGAAAAATAACTATGTTATTATTATGGCGGGAGGACTTGGGACTAGGCTTAAGG
AGCTAACTAAGTCAACTCCTAAGCCTATGCTGAAAGTTGGAGAACATCCTATGCTCCAACATATAATAAATAACTTCAAG
CAATATGGATATGACAAAATGCTTATTTCAGTAAATTATAAAGCCGATATAATAGAAAATTACTTTCAAGATGGAGGTGC
TTACGGTGTTAAAATTGATTATATACGGGAAAAAAAGAGAATGGGAACTTGTGGGGGAATAAAGCTTGCAAAAGAATATT
TGAATGCTCCTTTTTTTGTTACTAATGGAGATATATTCACCAATCTTAATGTAGAAGACATGATGAACTTTCATATAAAA
AATGCATTTGATATAACGGTAGGAGTTAGAAAACATTCTTTTCAAATTCCTTATGGAGTAATAAACTCAGAAAATGATGT
TATTAGAAGCATAGAAGAAAAACCTACTATGGATTACTTGATAAACGGTGGAATTTACTGTGTGAATCCGCATGTTATTG
ACTACATACCAGATGATGAATATTATGAGATAACAGATTTAATAAATAGATGCATACAAGAAGGAAAAAAAGTAGGAAGT
TATGAAATAAGAGATTACTGGATGGATATAGGCAGGATAGAAGATTACTACAAAGCAAATGAAGATGTGTATGACTTAAT
AGCTTGTGAGAAATTAGGTGATGAAAGTGATAAATAA

Upstream 100 bases:

>100_bases
GAAGAAAAATGAAAAATTATCATATGAAGAATTTATAAATGAACAAGAGCATATTATTAAGGCTTTACTAAAGTGAATTA
ATTAAAGATGGAGAATGAAT

Downstream 100 bases:

>100_bases
TAAAAGTGTTCTCTCAATAATACCTGCAAGGGGCGGATCTAAAGAGGTTCCAAGAAAAAATATAAAAAATTTGAACGGCA
AGCCGCTTATTGCATACTCC

Product: nucleotidyl transferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKNLGNILVCESTTLLETLNAINLNQKGTAIVVDKENKLLGTITDGDIRRAILENISLNSSIKNIYNKNCICFNESYDLT
KAMQYFTKSIKLIPIINKNQKVTSYLELTDVLLLESKNNYVIIMAGGLGTRLKELTKSTPKPMLKVGEHPMLQHIINNFK
QYGYDKMLISVNYKADIIENYFQDGGAYGVKIDYIREKKRMGTCGGIKLAKEYLNAPFFVTNGDIFTNLNVEDMMNFHIK
NAFDITVGVRKHSFQIPYGVINSENDVIRSIEEKPTMDYLINGGIYCVNPHVIDYIPDDEYYEITDLINRCIQEGKKVGS
YEIRDYWMDIGRIEDYYKANEDVYDLIACEKLGDESDK

Sequences:

>Translated_358_residues
MKNLGNILVCESTTLLETLNAINLNQKGTAIVVDKENKLLGTITDGDIRRAILENISLNSSIKNIYNKNCICFNESYDLT
KAMQYFTKSIKLIPIINKNQKVTSYLELTDVLLLESKNNYVIIMAGGLGTRLKELTKSTPKPMLKVGEHPMLQHIINNFK
QYGYDKMLISVNYKADIIENYFQDGGAYGVKIDYIREKKRMGTCGGIKLAKEYLNAPFFVTNGDIFTNLNVEDMMNFHIK
NAFDITVGVRKHSFQIPYGVINSENDVIRSIEEKPTMDYLINGGIYCVNPHVIDYIPDDEYYEITDLINRCIQEGKKVGS
YEIRDYWMDIGRIEDYYKANEDVYDLIACEKLGDESDK
>Mature_358_residues
MKNLGNILVCESTTLLETLNAINLNQKGTAIVVDKENKLLGTITDGDIRRAILENISLNSSIKNIYNKNCICFNESYDLT
KAMQYFTKSIKLIPIINKNQKVTSYLELTDVLLLESKNNYVIIMAGGLGTRLKELTKSTPKPMLKVGEHPMLQHIINNFK
QYGYDKMLISVNYKADIIENYFQDGGAYGVKIDYIREKKRMGTCGGIKLAKEYLNAPFFVTNGDIFTNLNVEDMMNFHIK
NAFDITVGVRKHSFQIPYGVINSENDVIRSIEEKPTMDYLINGGIYCVNPHVIDYIPDDEYYEITDLINRCIQEGKKVGS
YEIRDYWMDIGRIEDYYKANEDVYDLIACEKLGDESDK

Specific function: Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate [H]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=226, Percent_Identity=30.5309734513274, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI11761619, Length=227, Percent_Identity=30.3964757709251, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI133931050, Length=229, Percent_Identity=30.1310043668122, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320148, Length=224, Percent_Identity=32.1428571428571, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355443, Length=222, Percent_Identity=31.5315315315315, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24644084, Length=222, Percent_Identity=31.5315315315315, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 40951; Mature: 40951

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLGNILVCESTTLLETLNAINLNQKGTAIVVDKENKLLGTITDGDIRRAILENISLNS
CCCCCCEEEECCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHCCCCH
SIKNIYNKNCICFNESYDLTKAMQYFTKSIKLIPIINKNQKVTSYLELTDVLLLESKNNY
HHHHHHCCCEEEECCCCCHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHEEEEEECCCCE
VIIMAGGLGTRLKELTKSTPKPMLKVGEHPMLQHIINNFKQYGYDKMLISVNYKADIIEN
EEEEECCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
YFQDGGAYGVKIDYIREKKRMGTCGGIKLAKEYLNAPFFVTNGDIFTNLNVEDMMNFHIK
HHHCCCCEEEEEHEEHHHHHCCCCCHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHHCC
NAFDITVGVRKHSFQIPYGVINSENDVIRSIEEKPTMDYLINGGIYCVNPHVIDYIPDDE
CEEEEEEEEEECEEECCEEEECCCCHHHHHHHCCCCEEEEECCCEEEECCEEEEECCCCC
YYEITDLINRCIQEGKKVGSYEIRDYWMDIGRIEDYYKANEDVYDLIACEKLGDESDK
CCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNLGNILVCESTTLLETLNAINLNQKGTAIVVDKENKLLGTITDGDIRRAILENISLNS
CCCCCCEEEECCHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHCCCCH
SIKNIYNKNCICFNESYDLTKAMQYFTKSIKLIPIINKNQKVTSYLELTDVLLLESKNNY
HHHHHHCCCEEEECCCCCHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHEEEEEECCCCE
VIIMAGGLGTRLKELTKSTPKPMLKVGEHPMLQHIINNFKQYGYDKMLISVNYKADIIEN
EEEEECCCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
YFQDGGAYGVKIDYIREKKRMGTCGGIKLAKEYLNAPFFVTNGDIFTNLNVEDMMNFHIK
HHHCCCCEEEEEHEEHHHHHCCCCCHHHHHHHHHCCCEEEECCCEEECCCHHHHHHHHCC
NAFDITVGVRKHSFQIPYGVINSENDVIRSIEEKPTMDYLINGGIYCVNPHVIDYIPDDE
CEEEEEEEEEECEEECCEEEECCCCHHHHHHHCCCCEEEEECCCEEEECCEEEEECCCCC
YYEITDLINRCIQEGKKVGSYEIRDYWMDIGRIEDYYKANEDVYDLIACEKLGDESDK
CCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]