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The map label for this gene is tagA [H]

Identifier: 170754771

GI number: 170754771

Start: 3335607

End: 3336323

Strand: Reverse

Name: tagA [H]

Synonym: CLD_1448

Alternate gene names: 170754771

Gene position: 3336323-3335607 (Counterclockwise)

Preceding gene: 170757232

Following gene: 170756850

Centisome position: 84.29

GC content: 26.78

Gene sequence:

>717_bases
ATGAAAACAGAAATGTTAGGATATAGTATATTTAATGGTAGTAAAGAAGAACTTTTAAATATAATAGATAAATATGAAAA
AGTTAATATAATTTCTGGTAATCCAGAAGTTTTATATAATGGACTAAATAATGAAGAGTTATTCAAAAATTTTACAGATA
AAGATTCTATAATTATACCAGACGGAGTAGGTGTGGTTTTGGCTTCAAAAATTATAAAAAGTCCTGTAAAAGAAAAAATT
GCAGGGATTGAAGTAATGGATTCTATATTGAAAAAGTGTAATGAGAATGGTAAAGCTGTGTATTTGCTAGGAACTACGGA
AGATGTATTAAAAGAATGTGAGAGAAAGTTATTAATAAAGTACAAGAACTTAAATATTGTAGGTAAGCACAATGGTTTTT
TTGATATGGATAATTGTAAGGATATATTAGAAGATATTAAAGAGTCAAAACCTTATGCTTTATTTATAGCTATGGGATGT
CCAAGACAAGAAAAATTTATAAGTAGATATATGAACGAACTTCCTTGTAATATTTATATGGGTGTAGGAGGAAGTTTTGA
TGTGTTTGCTGGAAAAGTAAAAAGAGCACCTAGATGGATGATAAATTGTAATTTAGAGTGGTTATATAGAGTGGTTAAAG
AGCCTTATAGAATAAAAAGATTAGCATCTATACCTAAATTTTTATTAAAAGCAGCATTAAATAAAAGAAGCTATTAA

Upstream 100 bases:

>100_bases
ATTACTGCACAAGTATCATTAATTATAGTTTATTTACAAAGTTTGATATAATAACTATAATTAATGTATATTGTGCATTT
TTAATTTTAGGGGTGAATAA

Downstream 100 bases:

>100_bases
TATTTATTTTTAAATTAAAAAGCTACGAATTTGCAATATTATATTGTTAAACTCATAGCTTTTTATTATAAAAACTTATA
TTTTAATTGACTATTTTTTA

Product: WecB/TagA/CpsF family glycosyl transferase

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKTEMLGYSIFNGSKEELLNIIDKYEKVNIISGNPEVLYNGLNNEELFKNFTDKDSIIIPDGVGVVLASKIIKSPVKEKI
AGIEVMDSILKKCNENGKAVYLLGTTEDVLKECERKLLIKYKNLNIVGKHNGFFDMDNCKDILEDIKESKPYALFIAMGC
PRQEKFISRYMNELPCNIYMGVGGSFDVFAGKVKRAPRWMINCNLEWLYRVVKEPYRIKRLASIPKFLLKAALNKRSY

Sequences:

>Translated_238_residues
MKTEMLGYSIFNGSKEELLNIIDKYEKVNIISGNPEVLYNGLNNEELFKNFTDKDSIIIPDGVGVVLASKIIKSPVKEKI
AGIEVMDSILKKCNENGKAVYLLGTTEDVLKECERKLLIKYKNLNIVGKHNGFFDMDNCKDILEDIKESKPYALFIAMGC
PRQEKFISRYMNELPCNIYMGVGGSFDVFAGKVKRAPRWMINCNLEWLYRVVKEPYRIKRLASIPKFLLKAALNKRSY
>Mature_238_residues
MKTEMLGYSIFNGSKEELLNIIDKYEKVNIISGNPEVLYNGLNNEELFKNFTDKDSIIIPDGVGVVLASKIIKSPVKEKI
AGIEVMDSILKKCNENGKAVYLLGTTEDVLKECERKLLIKYKNLNIVGKHNGFFDMDNCKDILEDIKESKPYALFIAMGC
PRQEKFISRYMNELPCNIYMGVGGSFDVFAGKVKRAPRWMINCNLEWLYRVVKEPYRIKRLASIPKFLLKAALNKRSY

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=161, Percent_Identity=36.6459627329193, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 27240; Mature: 27240

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEMLGYSIFNGSKEELLNIIDKYEKVNIISGNPEVLYNGLNNEELFKNFTDKDSIIIP
CCCCCCCHHHCCCCHHHHHHHHHHHHEEEEECCCHHEEECCCCHHHHHHCCCCCCCEEEC
DGVGVVLASKIIKSPVKEKIAGIEVMDSILKKCNENGKAVYLLGTTEDVLKECERKLLIK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHEEE
YKNLNIVGKHNGFFDMDNCKDILEDIKESKPYALFIAMGCPRQEKFISRYMNELPCNIYM
ECCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEE
GVGGSFDVFAGKVKRAPRWMINCNLEWLYRVVKEPYRIKRLASIPKFLLKAALNKRSY
ECCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTEMLGYSIFNGSKEELLNIIDKYEKVNIISGNPEVLYNGLNNEELFKNFTDKDSIIIP
CCCCCCCHHHCCCCHHHHHHHHHHHHEEEEECCCHHEEECCCCHHHHHHCCCCCCCEEEC
DGVGVVLASKIIKSPVKEKIAGIEVMDSILKKCNENGKAVYLLGTTEDVLKECERKLLIK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHEEE
YKNLNIVGKHNGFFDMDNCKDILEDIKESKPYALFIAMGCPRQEKFISRYMNELPCNIYM
ECCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEE
GVGGSFDVFAGKVKRAPRWMINCNLEWLYRVVKEPYRIKRLASIPKFLLKAALNKRSY
ECCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]