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The map label for this gene is yfgC [C]

Identifier: 170750879

GI number: 170750879

Start: 4770008

End: 4771492

Strand: Reverse

Name: yfgC [C]

Synonym: Mrad2831_4490

Alternate gene names: 170750879

Gene position: 4771492-4770008 (Counterclockwise)

Preceding gene: 170750880

Following gene: 170750878

Centisome position: 78.51

GC content: 75.69

Gene sequence:

>1485_bases
ATGGGCGGGATCACGGGGCACATCATCGCGGGGCGGACCCGCGCGGCGGGCCGGCGCGCCCTCGGCGCGGCGGCGCTGGG
CGGCCTCGCCCTGCTGCTCGGCGCCTGCGTCGCCGACCAGACCGAGGCGACCGTGCGGCCGGCCGTGGTGCGGGTGCCCG
CGGAGGCGCCGCGCACCACCGGCCGCGAGCGCGCCGCGGATGCCGACCACCTCAAGCTCGTGGCCTCCTTCGGGGGCGAG
GCCCGGGCCCCCAACGTCACGCGGATGCTGACCGAGGTGACCGACCGCCTCGTGAAGGCGAGCGACCGGCCCGACCAGGC
CTACACGGTGACGCTCCTCGACTCGCCGGTGGTCAACGCCTTCGCGCTGCCGAACGGGCGGCTCTACGTCACCCGCGGCC
TCGTGGCCCTGGCGAGCGACACCTCCGAGGTGGCGGCCGTGCTGGCCCACGAGATGGCCCACGTGACCCTCAACCACGCC
ACCGCCCGCAGCGAGCTCGAGCTGCGCTCGGCGCTCGTCAGCCGCGTCGTGGCCGACGTGCTGAACGACCCCGATACCGG
CGCGCAGCTGCAGAGCCAGTCGCGCTTCGCGCTCGCCCGGTTCTCCCGCGAGCAGGAGCTGGAGGCCGACGCCACCGGCG
TGCGCACCCTCGCCAAGGCCGGCTACGATCCGTTCGCGGCCGGGCGCTTCCTCGCCGCGCTCAACCGCTCGACGGGGCTG
AAGTCCGGCAGCGCCGGCGCGCCCGACATGCTGGCGACCCACCCGGGCACGGCCGAGCGCATCAATCAGGTCACCCGGGC
GGCCCGCCGCATCGGCGCGCCGGGCATCGGCACCGACGACCGCGCCGCCTACCTCGCGGCGGTGGACGGGCTCGCCTACG
GCGACAACCCGCGCGACGGCGCGGTGCGCGGGCACCGCTTCATCCATCCCGGCCTCGGCATCGCCTTCGAGGTGCCGGAG
GGCTTCACCCTGGAGAACACCCGCTCGGCGGTGCTCGGGACCACCCAGGACGGCGGCCGGCGCCTGCTGTTCGATCAGAT
CGAGGCGAAGGACGGCCAGCCCCTCGAGGCGGTGCTCAAGGCGAGCTGGAACGACGCCTTCGACCCGGCCGGCTTCGAGA
CCCGGGACGTCGCCGGCCACCCGGCGGCCTTCGCGCTGTCGCGGGGGAAGGAGTGGACCTTCCGCCTCGCGGCCATCCGG
ATCGGGGACTCGACCTACCGGATGATCATGGCCGCCAAGGGCGCCACCGACCCCGACCCGGCCTTCCGCCGCTGGACCGC
GACCCTGGTCGCGGTCGCGCCCGACGAGGCGGTCCTGCGCCCCCTGCGGCTGCAGGTGGTCCAGGCCGCCTCGACCAGCG
CCGAGGACCTCGCCCGCCGCATGGCGGTGCCCGACCGGGCGCTCGACCGGTTCCTCGTCCTCAACGGGCTGGAGCGGGGC
GCCGCGCTGGTGCCGGGACGCGGCTACAAGATCGTCGTGGAATAG

Upstream 100 bases:

>100_bases
CGACCCTGGAGGTCGCCCTCGACGGGCTCGAGACGCTCGGGGAGACGGACCGGCCGGAGGCCGATTCGGACGGGGAACGG
GGATTGCGGCGCTGATCGCG

Downstream 100 bases:

>100_bases
CCGCCCTGCGCGCCCGCGCCTTGTGCCGGCGCGGGGCCCGGACATCCTGCCCGCGTCGTTCAGGGAGAGCGCGGTGATTC
GATTCTTCTACAATCTCAGC

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MGGITGHIIAGRTRAAGRRALGAAALGGLALLLGACVADQTEATVRPAVVRVPAEAPRTTGRERAADADHLKLVASFGGE
ARAPNVTRMLTEVTDRLVKASDRPDQAYTVTLLDSPVVNAFALPNGRLYVTRGLVALASDTSEVAAVLAHEMAHVTLNHA
TARSELELRSALVSRVVADVLNDPDTGAQLQSQSRFALARFSREQELEADATGVRTLAKAGYDPFAAGRFLAALNRSTGL
KSGSAGAPDMLATHPGTAERINQVTRAARRIGAPGIGTDDRAAYLAAVDGLAYGDNPRDGAVRGHRFIHPGLGIAFEVPE
GFTLENTRSAVLGTTQDGGRRLLFDQIEAKDGQPLEAVLKASWNDAFDPAGFETRDVAGHPAAFALSRGKEWTFRLAAIR
IGDSTYRMIMAAKGATDPDPAFRRWTATLVAVAPDEAVLRPLRLQVVQAASTSAEDLARRMAVPDRALDRFLVLNGLERG
AALVPGRGYKIVVE

Sequences:

>Translated_494_residues
MGGITGHIIAGRTRAAGRRALGAAALGGLALLLGACVADQTEATVRPAVVRVPAEAPRTTGRERAADADHLKLVASFGGE
ARAPNVTRMLTEVTDRLVKASDRPDQAYTVTLLDSPVVNAFALPNGRLYVTRGLVALASDTSEVAAVLAHEMAHVTLNHA
TARSELELRSALVSRVVADVLNDPDTGAQLQSQSRFALARFSREQELEADATGVRTLAKAGYDPFAAGRFLAALNRSTGL
KSGSAGAPDMLATHPGTAERINQVTRAARRIGAPGIGTDDRAAYLAAVDGLAYGDNPRDGAVRGHRFIHPGLGIAFEVPE
GFTLENTRSAVLGTTQDGGRRLLFDQIEAKDGQPLEAVLKASWNDAFDPAGFETRDVAGHPAAFALSRGKEWTFRLAAIR
IGDSTYRMIMAAKGATDPDPAFRRWTATLVAVAPDEAVLRPLRLQVVQAASTSAEDLARRMAVPDRALDRFLVLNGLERG
AALVPGRGYKIVVE
>Mature_493_residues
GGITGHIIAGRTRAAGRRALGAAALGGLALLLGACVADQTEATVRPAVVRVPAEAPRTTGRERAADADHLKLVASFGGEA
RAPNVTRMLTEVTDRLVKASDRPDQAYTVTLLDSPVVNAFALPNGRLYVTRGLVALASDTSEVAAVLAHEMAHVTLNHAT
ARSELELRSALVSRVVADVLNDPDTGAQLQSQSRFALARFSREQELEADATGVRTLAKAGYDPFAAGRFLAALNRSTGLK
SGSAGAPDMLATHPGTAERINQVTRAARRIGAPGIGTDDRAAYLAAVDGLAYGDNPRDGAVRGHRFIHPGLGIAFEVPEG
FTLENTRSAVLGTTQDGGRRLLFDQIEAKDGQPLEAVLKASWNDAFDPAGFETRDVAGHPAAFALSRGKEWTFRLAAIRI
GDSTYRMIMAAKGATDPDPAFRRWTATLVAVAPDEAVLRPLRLQVVQAASTSAEDLARRMAVPDRALDRFLVLNGLERGA
ALVPGRGYKIVVE

Specific function: Unknown

COG id: COG4784

COG function: function code R; Putative Zn-dependent protease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TPR repeat [H]

Homologues:

Organism=Homo sapiens, GI21686999, Length=168, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1788840, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915
- InterPro:   IPR011716
- InterPro:   IPR011990 [H]

Pfam domain/function: PF01435 Peptidase_M48; PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 52237; Mature: 52106

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGITGHIIAGRTRAAGRRALGAAALGGLALLLGACVADQTEATVRPAVVRVPAEAPRTT
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCC
GRERAADADHLKLVASFGGEARAPNVTRMLTEVTDRLVKASDRPDQAYTVTLLDSPVVNA
CHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
FALPNGRLYVTRGLVALASDTSEVAAVLAHEMAHVTLNHATARSELELRSALVSRVVADV
EECCCCCEEEEECEEEEECCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
LNDPDTGAQLQSQSRFALARFSREQELEADATGVRTLAKAGYDPFAAGRFLAALNRSTGL
HCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
KSGSAGAPDMLATHPGTAERINQVTRAARRIGAPGIGTDDRAAYLAAVDGLAYGDNPRDG
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
AVRGHRFIHPGLGIAFEVPEGFTLENTRSAVLGTTQDGGRRLLFDQIEAKDGQPLEAVLK
CCCCCEEECCCCCEEEECCCCCEECCCCCEEEECCCCCCCEEEEHHHCCCCCCCHHHHHH
ASWNDAFDPAGFETRDVAGHPAAFALSRGKEWTFRLAAIRIGDSTYRMIMAAKGATDPDP
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEEEEEECCCCEEEEEEECCCCCCCH
AFRRWTATLVAVAPDEAVLRPLRLQVVQAASTSAEDLARRMAVPDRALDRFLVLNGLERG
HHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCC
AALVPGRGYKIVVE
CEECCCCCCEEEEC
>Mature Secondary Structure 
GGITGHIIAGRTRAAGRRALGAAALGGLALLLGACVADQTEATVRPAVVRVPAEAPRTT
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCC
GRERAADADHLKLVASFGGEARAPNVTRMLTEVTDRLVKASDRPDQAYTVTLLDSPVVNA
CHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEE
FALPNGRLYVTRGLVALASDTSEVAAVLAHEMAHVTLNHATARSELELRSALVSRVVADV
EECCCCCEEEEECEEEEECCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
LNDPDTGAQLQSQSRFALARFSREQELEADATGVRTLAKAGYDPFAAGRFLAALNRSTGL
HCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
KSGSAGAPDMLATHPGTAERINQVTRAARRIGAPGIGTDDRAAYLAAVDGLAYGDNPRDG
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCC
AVRGHRFIHPGLGIAFEVPEGFTLENTRSAVLGTTQDGGRRLLFDQIEAKDGQPLEAVLK
CCCCCEEECCCCCEEEECCCCCEECCCCCEEEECCCCCCCEEEEHHHCCCCCCCHHHHHH
ASWNDAFDPAGFETRDVAGHPAAFALSRGKEWTFRLAAIRIGDSTYRMIMAAKGATDPDP
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEEEEEEECCCCEEEEEEECCCCCCCH
AFRRWTATLVAVAPDEAVLRPLRLQVVQAASTSAEDLARRMAVPDRALDRFLVLNGLERG
HHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCCCCC
AALVPGRGYKIVVE
CEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]