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The map label for this gene is yfcG [H]

Identifier: 170750878

GI number: 170750878

Start: 4769254

End: 4769934

Strand: Reverse

Name: yfcG [H]

Synonym: Mrad2831_4489

Alternate gene names: 170750878

Gene position: 4769934-4769254 (Counterclockwise)

Preceding gene: 170750879

Following gene: 170750872

Centisome position: 78.48

GC content: 69.16

Gene sequence:

>681_bases
GTGATTCGATTCTTCTACAATCTCAGCCCCAACCCCATGAAGGTCGCCCTCTGCCTCGAGGAGATGGGGCTGCCCTACGA
GCCGGTGCCGGTCGATACCCGCAAGGGCGAGCAGTTCGATCCGGCCTACACGGCCGTCAATCCGAACGGGAAGGTGCCGG
CGATCGTCGACGGCGACGTGACCGTGTTCGATTCGAACGCGATCCTGATGTACCTGGCGGGCAAGACCGGCCGGTTCCTG
CCGGAGGGCGAGCCCGTCCGCGGCGAGATGCTGTCCTGGCTGATGTTCGTGGCGACCGGCATCGGGCCGTTCTCCGGCCA
GTGCGTGCATTTCCGCCACTTCGCGCAGGACGGGGGTGCCTACGCCACCGAGCGCTACACCTTCGAGGCGCGCCGGCACT
GGGGCATCCTCGACCAGCGCCTCGCCGACCGCACCTACGTGCTGGGCGACACCTACACGATCGTCGACATGGCGGTCTGG
GGCTGGGCCCGGATGGTGCCCTTCATCCTCGGCGAGGGCGCCTTCGGGGACCTGCCCAACGTCAAGCGCCACCTCGACGC
GCTCAACGCGCGGCCGGCCGCCCAGGCCGCCGAGGCGCTGAAGGGCCGCCACGCCTTCAAGGCGGAGATGGACGCCGAGG
CGCGGAGCTTCATGTTCCGCGCCGTGCAGGGCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCGGCTACAAGATCGTCGTGGAATAGCCGCCCTGCGCGCCCGCGCCTTGTGCCGGCGCGGGGCCCGGACATCCTGCCCG
CGTCGTTCAGGGAGAGCGCG

Downstream 100 bases:

>100_bases
CACCACCGCGGACCGGTCCCGCGCCTCAGGGCGCGGGGGCGGTCACCGTGAGCATCGGCAGGGTGACGGAGAGCGTTCCG
GCCGGTGCATGTCCGGTGCC

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MIRFFYNLSPNPMKVALCLEEMGLPYEPVPVDTRKGEQFDPAYTAVNPNGKVPAIVDGDVTVFDSNAILMYLAGKTGRFL
PEGEPVRGEMLSWLMFVATGIGPFSGQCVHFRHFAQDGGAYATERYTFEARRHWGILDQRLADRTYVLGDTYTIVDMAVW
GWARMVPFILGEGAFGDLPNVKRHLDALNARPAAQAAEALKGRHAFKAEMDAEARSFMFRAVQGAA

Sequences:

>Translated_226_residues
MIRFFYNLSPNPMKVALCLEEMGLPYEPVPVDTRKGEQFDPAYTAVNPNGKVPAIVDGDVTVFDSNAILMYLAGKTGRFL
PEGEPVRGEMLSWLMFVATGIGPFSGQCVHFRHFAQDGGAYATERYTFEARRHWGILDQRLADRTYVLGDTYTIVDMAVW
GWARMVPFILGEGAFGDLPNVKRHLDALNARPAAQAAEALKGRHAFKAEMDAEARSFMFRAVQGAA
>Mature_226_residues
MIRFFYNLSPNPMKVALCLEEMGLPYEPVPVDTRKGEQFDPAYTAVNPNGKVPAIVDGDVTVFDSNAILMYLAGKTGRFL
PEGEPVRGEMLSWLMFVATGIGPFSGQCVHFRHFAQDGGAYATERYTFEARRHWGILDQRLADRTYVLGDTYTIVDMAVW
GWARMVPFILGEGAFGDLPNVKRHLDALNARPAAQAAEALKGRHAFKAEMDAEARSFMFRAVQGAA

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=204, Percent_Identity=37.2549019607843, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI87082195, Length=215, Percent_Identity=36.2790697674419, Blast_Score=119, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324100, Length=242, Percent_Identity=29.7520661157025, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571670, Length=168, Percent_Identity=27.3809523809524, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 25085; Mature: 25085

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFFYNLSPNPMKVALCLEEMGLPYEPVPVDTRKGEQFDPAYTAVNPNGKVPAIVDGDV
CEEEEEECCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCE
TVFDSNAILMYLAGKTGRFLPEGEPVRGEMLSWLMFVATGIGPFSGQCVHFRHFAQDGGA
EEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCC
YATERYTFEARRHWGILDQRLADRTYVLGDTYTIVDMAVWGWARMVPFILGEGAFGDLPN
EEEEEEEEHHHHHCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
VKRHLDALNARPAAQAAEALKGRHAFKAEMDAEARSFMFRAVQGAA
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRFFYNLSPNPMKVALCLEEMGLPYEPVPVDTRKGEQFDPAYTAVNPNGKVPAIVDGDV
CEEEEEECCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEECCCE
TVFDSNAILMYLAGKTGRFLPEGEPVRGEMLSWLMFVATGIGPFSGQCVHFRHFAQDGGA
EEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCC
YATERYTFEARRHWGILDQRLADRTYVLGDTYTIVDMAVWGWARMVPFILGEGAFGDLPN
EEEEEEEEHHHHHCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
VKRHLDALNARPAAQAAEALKGRHAFKAEMDAEARSFMFRAVQGAA
HHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]