Click here to switch to the map view.

The map label for this gene is wrbA

Identifier: 170750229

GI number: 170750229

Start: 4076584

End: 4077186

Strand: Reverse

Name: wrbA

Synonym: Mrad2831_3831

Alternate gene names: 170750229

Gene position: 4077186-4076584 (Counterclockwise)

Preceding gene: 170750231

Following gene: 170750227

Centisome position: 67.08

GC content: 69.65

Gene sequence:

>603_bases
ATGGCGAAGGTTCTGGTGCTGTACTACTCGACCTACGGTCACGTGGAGCAGATGGCCTACGCCGTCGCCGAGGGCGCCCG
CGAGACGGGGGCCGAGGTCGTCGTGAAGCGCGTGCCCGAGCTGGTGCCGGAGGAGGTCGCCCGGCAGAACCACTTCAAGC
TGGATCAGGCGGCGCCGGTCGCGACCGTCGCCGAGCTCGCCGACTACGACGCGATCATCTTCGGCACGCCGACCCGCTAC
GGCAACATGGCCTCGCAGATGAAGCAGTTCATCGACCAGACCGGCGGGCTCTGGATGAAGGGCGCGCTGGTCGGCAAGGT
CGGTTCGGTCTTCACCTCCACGGCCTCGCAGCACGGCGGCCAGGAGACGACGCTGACAAGCTTCCACACGGTCCTGTTCC
ACCACGGCATGGTTGTGGTCGGCCTGCCCTACAGCTTCCAGGGACAGGCGGGCGTCGAGGCGGTGAAGGGCAACACGCCC
TACGGCGCCAGCACGATCGCGGACGGCGACGGGTCGCGCCAGCCGAGCGCCGTCGAGCTGGAGGGCGCGCGGTTCCAGGG
GCGCCACGTGGCCGGCATCGCGGCCAAGCTGGCCCGGGACTGA

Upstream 100 bases:

>100_bases
GCATGTCGGGGCATTCTTGCAAGACGGCAAATGCGCGATGCAGGGGCCATCCGCCGGCCGACGATTCGGCCGGACGTCCG
ACAGGCAGGAGAGACCACAC

Downstream 100 bases:

>100_bases
GGAGCCAAGAAAAAAGGCTCGGATTGCTCCGAGCCTGAAAGGAAAAAGGCCATTGGGGGCTGAGAAGGCCTTCGTGATCA
GTAAACGGGTCAGGCCGAAC

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MAKVLVLYYSTYGHVEQMAYAVAEGARETGAEVVVKRVPELVPEEVARQNHFKLDQAAPVATVAELADYDAIIFGTPTRY
GNMASQMKQFIDQTGGLWMKGALVGKVGSVFTSTASQHGGQETTLTSFHTVLFHHGMVVVGLPYSFQGQAGVEAVKGNTP
YGASTIADGDGSRQPSAVELEGARFQGRHVAGIAAKLARD

Sequences:

>Translated_200_residues
MAKVLVLYYSTYGHVEQMAYAVAEGARETGAEVVVKRVPELVPEEVARQNHFKLDQAAPVATVAELADYDAIIFGTPTRY
GNMASQMKQFIDQTGGLWMKGALVGKVGSVFTSTASQHGGQETTLTSFHTVLFHHGMVVVGLPYSFQGQAGVEAVKGNTP
YGASTIADGDGSRQPSAVELEGARFQGRHVAGIAAKLARD
>Mature_199_residues
AKVLVLYYSTYGHVEQMAYAVAEGARETGAEVVVKRVPELVPEEVARQNHFKLDQAAPVATVAELADYDAIIFGTPTRYG
NMASQMKQFIDQTGGLWMKGALVGKVGSVFTSTASQHGGQETTLTSFHTVLFHHGMVVVGLPYSFQGQAGVEAVKGNTPY
GASTIADGDGSRQPSAVELEGARFQGRHVAGIAAKLARD

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain

Homologues:

Organism=Escherichia coli, GI1787239, Length=198, Percent_Identity=64.1414141414141, Blast_Score=236, Evalue=8e-64,
Organism=Saccharomyces cerevisiae, GI6319849, Length=200, Percent_Identity=43.5, Blast_Score=166, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=40.7035175879397, Blast_Score=141, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6319526, Length=201, Percent_Identity=32.8358208955224, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): WRBA_METRJ (B1LY35)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001756489.1
- ProteinModelPortal:   B1LY35
- SMR:   B1LY35
- GeneID:   6139885
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_3831
- HOGENOM:   HBG686708
- OMA:   TITSFHT
- ProtClustDB:   PRK03767
- HAMAP:   MF_01017
- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025
- TIGRFAMs:   TIGR01755

Pfam domain/function: PF03358 FMN_red

EC number: NA

Molecular weight: Translated: 21274; Mature: 21143

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLVLYYSTYGHVEQMAYAVAEGARETGAEVVVKRVPELVPEEVARQNHFKLDQAAPV
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ATVAELADYDAIIFGTPTRYGNMASQMKQFIDQTGGLWMKGALVGKVGSVFTSTASQHGG
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCC
QETTLTSFHTVLFHHGMVVVGLPYSFQGQAGVEAVKGNTPYGASTIADGDGSRQPSAVEL
CCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCEEEE
EGARFQGRHVAGIAAKLARD
CCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AKVLVLYYSTYGHVEQMAYAVAEGARETGAEVVVKRVPELVPEEVARQNHFKLDQAAPV
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ATVAELADYDAIIFGTPTRYGNMASQMKQFIDQTGGLWMKGALVGKVGSVFTSTASQHGG
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCC
QETTLTSFHTVLFHHGMVVVGLPYSFQGQAGVEAVKGNTPYGASTIADGDGSRQPSAVEL
CCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCEEEE
EGARFQGRHVAGIAAKLARD
CCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA