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The map label for this gene is fadE25 [H]

Identifier: 170750227

GI number: 170750227

Start: 4073575

End: 4075314

Strand: Reverse

Name: fadE25 [H]

Synonym: Mrad2831_3829

Alternate gene names: 170750227

Gene position: 4075314-4073575 (Counterclockwise)

Preceding gene: 170750229

Following gene: 170750226

Centisome position: 67.05

GC content: 74.37

Gene sequence:

>1740_bases
ATGAGTTACCGCGCCCCGGTCCCCGAGATGCTCTTCACGCTGCGGCACGTGGCCGGGCTCGACGCGGTCGATCCCGACGA
CGCCGAGGCGATCCTGACCGAGGCCGGCCGGATCGCCGCCGGCGTGATCGCGCCGCTCAACCGGGTCGGCGACCGGCACG
GCACCCCCTTCGCGGACGGGCAGGTCACCACGCCGCCGGGCTGGCGCGAGGCGTACCGCACCTTCACGGAGGGCGGCTGG
AACGGGCTCTCGGCCGAGGCCGATCACGGCGGCCAGGGCCTGCCGAAGCTGATCGAGGCCGCCTGCACCGAGATGTGGAA
CGGTGCCAACCTCGCCTTCGGCCTCTGCCCGCTCCTGACCCAGGGCGGCATCGAGGCGCTCGCCGCCCACGGCTCCGACG
ACCTGAAGGCGCGCTACCTCGAGAAGCTGGTCTCGGGCGCGTGGCCCGCCACCATGAACCTGACCGAGCCGCAGGCGGGC
TCCGACCTCGCCCTGCTGCGCACCCGGGCCGTGCCGGCGGGCGACGGCACCTACCGGATCACCGGCAACAAGATCTACAT
CACCTACGGCGAGCACGATCTCGCCGACAACATCGTCCACCTCGTCCTGGCGCGCCTGCCCGACGCGCCCGCCGGCACGC
GGGGCATCTCCCTGTTCCTGGTGCCGAAGGTGCTACCGGACGGCACCCGCAACGACCTGCGCTGCTCCGGCATCGAGCAC
AAGCTCGGCATCCACGCCTCGCCGACCTGCTCCATGGCGTTCGGCGACCAGGTCGGCGCGACCGGCTGGCTGATCGGCCA
GGAGAACAAGGGGCTGGCCTGCATGTTCACGATGATGAACGCGGCCCGGCTCAATGTCGGCCTGCAGGGCGTCGGCGTCG
CCGAGGCCGCGACCCAGCGCGCGCTCGCCTACGCGCAGGAGCGCCGCCAGGGCAAGGCCGTCGGCGCCGCCGAGGCGACG
AGCCCGATCGCCGCCCATCCGGACGTGCAGCGCATGCTGCTTACCATGAAGGCCTCGACGGCGGCCGCCCGCGCCATCTG
CTACCTCACCGCCGCGGCCCTCGACGCCGCGAAGGGGCCGGAGGGGCAGGCCGCCCTGGACCGCGCCTCGCTGCTGACCC
CGGTGGCGAAGGCCTTCGCCACCGACCTCGCCAACGAGGTGACCTCGCTCGGCGTGCAGGTCCACGGCGGCATGGGCTTC
GTGGAGGAGACCGGGGCGGCGCAGCTCATGCGCGACGCCCGGATCCTCGGCATCTACGAGGGGACCAACGGCATCCAGGC
CATCGACCTCGCCGCCCGCAAGCTGCCGCTGAACGGTGGGGGCACCGCGCGGTCGCAGATCGCCTGGATGCGCCGGGCCG
CGGAGGGGCTGCTCAAGGCCGGCGACCCCGCCTTCGGCCACATGGCGGCGCGGCTGCGCGACGGGATCGGCAGCCTCGAC
CGGGCGACGAGCCACCAGCTCGCCGCGCTGAGCTCGAACCGCCCCGAGGCGGCGCTCGCCGGCGCGACGCCGTACCTGCG
CCTGTTCGGCCTGACGCTGGGCGCCGCCTGCCTCGCGCGCAGCGCGCTCGCCGCGAGCGCCGCCCGGAAGGCGGGCGAGA
CGGACCCGGCGCACGCGGCCCGCATCGCGCTCGCCCGGTTCTACGCCGAGAACCTCCTGGTGGCCGCTTCCGGCCTGGAG
CAGGCGGTGGTCGAGGGCGGCGCCTTCACGGACGACGCCGCCCTGGCGCTGGCGGTTTGA

Upstream 100 bases:

>100_bases
CCGCGCGCCTATCCTCGCCCCGCCCTAGCGCCGGTGCGCGGGCGCGGTCAAACCCGCCCCGGACCGAACGAGCGGGCGGG
CCGCCACACGGGAGGATCGT

Downstream 100 bases:

>100_bases
GGAGCGGACCATGGCCGAACCCGTCACGATCGACGACCTCGCGGGCGGCGTCCGCCTGATCACCCTGAACCGTCCGGAGA
AGAAGAACGCCCTCACGGGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSYRAPVPEMLFTLRHVAGLDAVDPDDAEAILTEAGRIAAGVIAPLNRVGDRHGTPFADGQVTTPPGWREAYRTFTEGGW
NGLSAEADHGGQGLPKLIEAACTEMWNGANLAFGLCPLLTQGGIEALAAHGSDDLKARYLEKLVSGAWPATMNLTEPQAG
SDLALLRTRAVPAGDGTYRITGNKIYITYGEHDLADNIVHLVLARLPDAPAGTRGISLFLVPKVLPDGTRNDLRCSGIEH
KLGIHASPTCSMAFGDQVGATGWLIGQENKGLACMFTMMNAARLNVGLQGVGVAEAATQRALAYAQERRQGKAVGAAEAT
SPIAAHPDVQRMLLTMKASTAAARAICYLTAAALDAAKGPEGQAALDRASLLTPVAKAFATDLANEVTSLGVQVHGGMGF
VEETGAAQLMRDARILGIYEGTNGIQAIDLAARKLPLNGGGTARSQIAWMRRAAEGLLKAGDPAFGHMAARLRDGIGSLD
RATSHQLAALSSNRPEAALAGATPYLRLFGLTLGAACLARSALAASAARKAGETDPAHAARIALARFYAENLLVAASGLE
QAVVEGGAFTDDAALALAV

Sequences:

>Translated_579_residues
MSYRAPVPEMLFTLRHVAGLDAVDPDDAEAILTEAGRIAAGVIAPLNRVGDRHGTPFADGQVTTPPGWREAYRTFTEGGW
NGLSAEADHGGQGLPKLIEAACTEMWNGANLAFGLCPLLTQGGIEALAAHGSDDLKARYLEKLVSGAWPATMNLTEPQAG
SDLALLRTRAVPAGDGTYRITGNKIYITYGEHDLADNIVHLVLARLPDAPAGTRGISLFLVPKVLPDGTRNDLRCSGIEH
KLGIHASPTCSMAFGDQVGATGWLIGQENKGLACMFTMMNAARLNVGLQGVGVAEAATQRALAYAQERRQGKAVGAAEAT
SPIAAHPDVQRMLLTMKASTAAARAICYLTAAALDAAKGPEGQAALDRASLLTPVAKAFATDLANEVTSLGVQVHGGMGF
VEETGAAQLMRDARILGIYEGTNGIQAIDLAARKLPLNGGGTARSQIAWMRRAAEGLLKAGDPAFGHMAARLRDGIGSLD
RATSHQLAALSSNRPEAALAGATPYLRLFGLTLGAACLARSALAASAARKAGETDPAHAARIALARFYAENLLVAASGLE
QAVVEGGAFTDDAALALAV
>Mature_578_residues
SYRAPVPEMLFTLRHVAGLDAVDPDDAEAILTEAGRIAAGVIAPLNRVGDRHGTPFADGQVTTPPGWREAYRTFTEGGWN
GLSAEADHGGQGLPKLIEAACTEMWNGANLAFGLCPLLTQGGIEALAAHGSDDLKARYLEKLVSGAWPATMNLTEPQAGS
DLALLRTRAVPAGDGTYRITGNKIYITYGEHDLADNIVHLVLARLPDAPAGTRGISLFLVPKVLPDGTRNDLRCSGIEHK
LGIHASPTCSMAFGDQVGATGWLIGQENKGLACMFTMMNAARLNVGLQGVGVAEAATQRALAYAQERRQGKAVGAAEATS
PIAAHPDVQRMLLTMKASTAAARAICYLTAAALDAAKGPEGQAALDRASLLTPVAKAFATDLANEVTSLGVQVHGGMGFV
EETGAAQLMRDARILGIYEGTNGIQAIDLAARKLPLNGGGTARSQIAWMRRAAEGLLKAGDPAFGHMAARLRDGIGSLDR
ATSHQLAALSSNRPEAALAGATPYLRLFGLTLGAACLARSALAASAARKAGETDPAHAARIALARFYAENLLVAASGLEQ
AVVEGGAFTDDAALALAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI76496475, Length=361, Percent_Identity=28.5318559556787, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4557235, Length=361, Percent_Identity=28.5318559556787, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4501859, Length=413, Percent_Identity=27.1186440677966, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226958412, Length=363, Percent_Identity=27.5482093663912, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI21361497, Length=357, Percent_Identity=26.6106442577031, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI226958414, Length=363, Percent_Identity=27.2727272727273, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4501857, Length=312, Percent_Identity=29.4871794871795, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4557231, Length=305, Percent_Identity=31.4754098360656, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI187960098, Length=305, Percent_Identity=31.4754098360656, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=28.3746556473829, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI4557233, Length=305, Percent_Identity=29.8360655737705, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI87082384, Length=384, Percent_Identity=28.90625, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081958, Length=320, Percent_Identity=27.5, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=314, Percent_Identity=31.5286624203822, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=395, Percent_Identity=27.3417721518987, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71985184, Length=391, Percent_Identity=27.8772378516624, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=31.6076294277929, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=296, Percent_Identity=30.4054054054054, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=346, Percent_Identity=30.9248554913295, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI86563381, Length=331, Percent_Identity=28.7009063444109, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI86563383, Length=331, Percent_Identity=28.7009063444109, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=303, Percent_Identity=29.3729372937294, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17533517, Length=430, Percent_Identity=26.7441860465116, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=364, Percent_Identity=26.3736263736264, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=364, Percent_Identity=26.0989010989011, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=349, Percent_Identity=26.0744985673352, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=187, Percent_Identity=30.4812834224599, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=235, Percent_Identity=27.6595744680851, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=322, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24660351, Length=307, Percent_Identity=33.8762214983713, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21355753, Length=435, Percent_Identity=26.6666666666667, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356377, Length=305, Percent_Identity=30.1639344262295, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281363737, Length=382, Percent_Identity=25.6544502617801, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666513, Length=353, Percent_Identity=28.6118980169972, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646207, Length=362, Percent_Identity=26.5193370165746, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19920834, Length=306, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 60055; Mature: 59924

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRAPVPEMLFTLRHVAGLDAVDPDDAEAILTEAGRIAAGVIAPLNRVGDRHGTPFADG
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
QVTTPPGWREAYRTFTEGGWNGLSAEADHGGQGLPKLIEAACTEMWNGANLAFGLCPLLT
EEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
QGGIEALAAHGSDDLKARYLEKLVSGAWPATMNLTEPQAGSDLALLRTRAVPAGDGTYRI
HCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEE
TGNKIYITYGEHDLADNIVHLVLARLPDAPAGTRGISLFLVPKVLPDGTRNDLRCSGIEH
ECCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCC
KLGIHASPTCSMAFGDQVGATGWLIGQENKGLACMFTMMNAARLNVGLQGVGVAEAATQR
CCCCCCCCCCCEECCCCCCCCEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHH
ALAYAQERRQGKAVGAAEATSPIAAHPDVQRMLLTMKASTAAARAICYLTAAALDAAKGP
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGQAALDRASLLTPVAKAFATDLANEVTSLGVQVHGGMGFVEETGAAQLMRDARILGIYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCHHHHHHCCEEEEEEE
GTNGIQAIDLAARKLPLNGGGTARSQIAWMRRAAEGLLKAGDPAFGHMAARLRDGIGSLD
CCCCCEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
RATSHQLAALSSNRPEAALAGATPYLRLFGLTLGAACLARSALAASAARKAGETDPAHAA
HHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RIALARFYAENLLVAASGLEQAVVEGGAFTDDAALALAV
HHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCCEEEEC
>Mature Secondary Structure 
SYRAPVPEMLFTLRHVAGLDAVDPDDAEAILTEAGRIAAGVIAPLNRVGDRHGTPFADG
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
QVTTPPGWREAYRTFTEGGWNGLSAEADHGGQGLPKLIEAACTEMWNGANLAFGLCPLLT
EEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
QGGIEALAAHGSDDLKARYLEKLVSGAWPATMNLTEPQAGSDLALLRTRAVPAGDGTYRI
HCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEE
TGNKIYITYGEHDLADNIVHLVLARLPDAPAGTRGISLFLVPKVLPDGTRNDLRCSGIEH
ECCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCC
KLGIHASPTCSMAFGDQVGATGWLIGQENKGLACMFTMMNAARLNVGLQGVGVAEAATQR
CCCCCCCCCCCEECCCCCCCCEEEEECCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHH
ALAYAQERRQGKAVGAAEATSPIAAHPDVQRMLLTMKASTAAARAICYLTAAALDAAKGP
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGQAALDRASLLTPVAKAFATDLANEVTSLGVQVHGGMGFVEETGAAQLMRDARILGIYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCHHHHHHCCEEEEEEE
GTNGIQAIDLAARKLPLNGGGTARSQIAWMRRAAEGLLKAGDPAFGHMAARLRDGIGSLD
CCCCCEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHH
RATSHQLAALSSNRPEAALAGATPYLRLFGLTLGAACLARSALAASAARKAGETDPAHAA
HHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RIALARFYAENLLVAASGLEQAVVEGGAFTDDAALALAV
HHHHHHHHHHHHHEECCCHHHHHHCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]